A Novel MMP-2 Inhibitor 3-azidowithaferin A (3-azidoWA) Abrogates Cancer Cell Invasion and Angiogenesis by Modulating Extracellular Par-4

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Rah, Bilal ^a   Amin, Hina ^a   Yousuf, Khalid ^a   Khan, Sheema ^a   Jamwal, Gayatri ^a   Mukherjee, Debaraj ^a   Goswami, Anindya ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

3 AZIDOWITHAFERIN A; GELATIN; GELATINASE A; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR 4; UNCLASSIFIED DRUG; WITHAFERIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL INVASION; CELL MOTILITY; CHEMOSENSITIVITY; COLONY FORMATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROSTATE CANCER; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UTERINE CERVIX CANCER; WOUND HEALING; ZYMOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AZIDES; BIOLOGICAL ASSAY; CELL LINE, TUMOR; CELL MOVEMENT; COLLAGEN; DRUG COMBINATIONS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LAMININ; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE INHIBITORS; MICE; MICE, INBRED C57BL; NEOPLASM INVASIVENESS; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHORYLATION; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION; WITHANOLIDES;

ANIMALIA;

EID: 84866052111     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044039     Document Type: Article

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