Decreased incidence of prostate cancer with selenium supplementation: Results of a double-blind cancer prevention trial

British Journal of Urology

Volumn 81, Issue 5, 1998, Pages 730-734

  Clark, L C ^a,h,i   Dalkin, B ^b,h   Krongrad, A ^b,h   Combs Jr , G F ^c,h   Turnbull, B W ^c,h   Slate, E H ^c,h   Witherington, R ^d   Herlong, J H ^e   Janosko, E ^f   Carpenter, D ^g   Borosso, C ^g   Falk, S ^g   Rounder, J ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c Cornell University ^*  (United States)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

^e UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f EAST CAROLINA UNIVERSITY   (United States)

^g UNIVERSITY OF CONNECTICUT   (United States)

^h Department of Epidemiology ^*

ⁱ UNIVERSITY OF ARIZONA   (United States)

Author keywords

Cancer screening; Chemoprevention; Clinical trials; Diet; Epidemiology; Nutrition; Prostate cancer; Selenium; Trace minerals

Indexed keywords

PROSTATE SPECIFIC ANTIGEN; SELENIUM; SELENO PRECISE; TRACE ELEMENT; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CANCER MORTALITY; CANCER PREVENTION; CLINICAL TRIAL; COLORECTAL CANCER; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROSTATE CANCER; RANDOMIZED CONTROLLED TRIAL; SKIN CARCINOMA; SQUAMOUS CELL CARCINOMA;

CARCINOMA, BASAL CELL; CARCINOMA, SQUAMOUS CELL; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PROSTATIC NEOPLASMS; SELENIUM; TREATMENT OUTCOME;

EID: 0031819215     PISSN: 00071331     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-410X.1998.00630.x     Document Type: Article

References (21)

1. Parker SL, Tong T, Bolden S, Wingo PA. Cancer statistics, 1996. CA Cancer J Clin 1996; 46: 5-7
2. Whittemore AS, Kolonel LN, Wu AH et al. Prostate cancer in blacks, whites, and Asians in the United States and Canada. J Nat Cancer Inst 1995; 87: 652-61
3. Kolonel LN. Nutrition and prostate cancer. Cancer Cause Control 1996; 7: 83-94
4. Wynder EL, Rose DP, Cohen LA. Nutrition and prostate cancer, a proposal for dietary intervention. Nutr Cancer 1994; 22: 1
5. Giovannucci E, Rimm EB, Colditz GA et al. A prospective study of dietary fat and risk of prostate cancer. J Nat Cancer Inst 1993; 85: 1571
6. Adlercreutz H, Honjo H, Higashi A et al. Urinary excretion of ligands and isoflavonoid phytoestrogens in Japanese men and women. Am J Clin Nutr 1991; 54: 1093-5
7. Wynder EL. Editorial: prostate cancer - nutrition adjunct therapy. J Urol 1996; 56: 1364-6
8. Rohan TE, Howe GR, Burch JD, Jain M. Dietary factors and risk of prostate cancer. A case-control study in Ontario, Canada. Cancer Causes Control 1995; 6: 145-54
9. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. New Engl J Med 1994; 330: 1029
10. Criqui MH. Selenium, retinol, retinol-binding protein and uric acid associations with cancer mortality in a population based prospective case-control study. Ann Epidemiol 1991; 1: 385-93
11. Hardell L, Degerman A, Tomic R, Marklund SL, Bergfors M. Levels of selenium in plasma and glutathione peroxidase in erythrocytes in patients with prostate cancer or benign hyperplasia. Eur J Cancer Prev 1995; 4: 91-5
12. Brawley OW, Thompson IM. Chemoprevention of prostate cancer. Urology 1994; 43: 594-9
13. Tsukamoto S, Akaza H, Imada S et al. Chemoprevention of rat prostate carcinogenesis by use of finasteride or casodex. J Nat Cancer Inst 1995; 87: 842-3
14. Clark LC. The epidemiology of selenium and cancer. Fed Proc 1985; 44: 2584-9
15. Bedwal RS, Nair N, Sharma MP, Mathur RS. Selenium - its biological perspectives. Med Hypoth 1993; 41: 150-9
16. Potmis A, Nonavinakere VK, Rasek HR, Early JL. Effect of selenium (Se) on plasma ACTH, beta-androphin, corticosterone and glucose in rat: Influence of adrenal enucleation and metyrapone pretreatment. Toxicol 1993; 79: 1-9
17. Kalckloxch M, Kyriakopoulos A, Hammel C, Behne D. A new selenoprotein found in the glandular epithelial cells of the rat prostate. Biochem Biophys Res Comm 1995; 217: 162-70
18. Olson OE, Palmer IS, Cary EE. Modification of the official fluorometric method for selenium in plants. J Assoc Off Anal Chem 1975; 58: 117-26
19. McShane LM, Clark LC, Combs GF Jr, Turnbull BW. Reporting the accuracy of biochemical measurements for epidemiologic and nutrition studies. Am J Clin Nutr 1991; 53: 1354-60
20. Clark LC, Combs GF Jr, Turnbull BW et al. For The Nutritional Prevention of Cancer Study Group. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: a randomized clinical trial. JAMA 1996; 76: 1957-6
21. Rayman MP. Dietary selenium. Time to act. Br Med J 1997; 114: 387-8