The beagle dog MicroRNA tissue atlas: Identifying translatable biomarkers of organ toxicity

BMC Genomics

Volumn 17, Issue 1, 2016, Pages

  Koenig, Erik M ^a   Fisher, Craig ^a   Bernard, Hugues ^a   Wolenski, Francis S ^a   Gerrein, Joseph ^a   Carsillo, Mary ^a   Gallacher, Matt ^a   Tse, Aimy ^a   Peters, Rachel ^a   Smith, Aaron ^b   Meehan, Alexa ^a   Tirrell, Stephen ^a   Kirby, Patrick ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CERULETIDE; MICRORNA; MICRORNA 122; MICRORNA 885; UNCLASSIFIED DRUG; TRANSCRIPTOME;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BEAGLE; BRAIN INJURY; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENETIC SCREENING; HEART INJURY; IN VIVO STUDY; KIDNEY INJURY; LIVER INJURY; LIVER TOXICITY; MICROSCOPY; NEXT GENERATION SEQUENCING; NONHUMAN; ORGAN INJURY; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA SEQUENCE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; VALIDATION PROCESS; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGY; CLUSTER ANALYSIS; DOG; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SEQUENCING; MALE; MOLECULAR GENETICS; PROCEDURES;

ANIMALS; BIOMARKERS; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; DOGS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; MALE; MICRORNAS; MOLECULAR SEQUENCE ANNOTATION; ORGAN SPECIFICITY; TRANSCRIPTOME;

EID: 84982190021     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-016-2958-x     Document Type: Article

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