-
1
-
-
84881027019
-
Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital
-
Antoine D.J., Dear J.W., Lewis P.S., Platt V., Coyle J., Masson M., Thanacoody R.H., Gray A.J., Webb D.J., Moggs J.G., Bateman D.N., Goldring C.E., Park B.K. Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital. Hepatology 2013, 58(2):777-787. 10.1002/hep.26294.
-
(2013)
Hepatology
, vol.58
, Issue.2
, pp. 777-787
-
-
Antoine, D.J.1
Dear, J.W.2
Lewis, P.S.3
Platt, V.4
Coyle, J.5
Masson, M.6
Thanacoody, R.H.7
Gray, A.J.8
Webb, D.J.9
Moggs, J.G.10
Bateman, D.N.11
Goldring, C.E.12
Park, B.K.13
-
2
-
-
0022911277
-
Evaluating toxin-induced hepatic injury in rats by laboratory results and discriminant analysis
-
Carakostas M.C., Gossett K.A., Church G.E., Cleghorn B.L. Evaluating toxin-induced hepatic injury in rats by laboratory results and discriminant analysis. Vet. Pathol. 1986, 23(3):264-269.
-
(1986)
Vet. Pathol.
, vol.23
, Issue.3
, pp. 264-269
-
-
Carakostas, M.C.1
Gossett, K.A.2
Church, G.E.3
Cleghorn, B.L.4
-
3
-
-
77957176666
-
One-year dietary toxicity study with methidathion in beagle dogs
-
Chang J.C., Walberg J.A., Campbell W.R. One-year dietary toxicity study with methidathion in beagle dogs. Fundam. Appl. Toxicol. 1992, 19(2):307-314.
-
(1992)
Fundam. Appl. Toxicol.
, vol.19
, Issue.2
, pp. 307-314
-
-
Chang, J.C.1
Walberg, J.A.2
Campbell, W.R.3
-
4
-
-
84896450857
-
Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives
-
Fontana R.J. Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives. Gastroenterology 2013, 10.1053/j.gastro.2013.12.032.
-
(2013)
Gastroenterology
-
-
Fontana, R.J.1
-
5
-
-
84864151938
-
The effects of heparins on the liver: application of mechanistic serum biomarkers in a randomized study in healthy volunteers
-
Harrill A.H., Roach J., Fier I., Eaddy J.S., Kurtz C.L., Antoine D.J., Spencer D.M., Kishimoto T.K., Pisetsky D.S., Park B.K., Watkins P.B. The effects of heparins on the liver: application of mechanistic serum biomarkers in a randomized study in healthy volunteers. Clin. Pharmacol. Ther. 2012, 92(2):214-220. 10.1038/clpt.2012.40.
-
(2012)
Clin. Pharmacol. Ther.
, vol.92
, Issue.2
, pp. 214-220
-
-
Harrill, A.H.1
Roach, J.2
Fier, I.3
Eaddy, J.S.4
Kurtz, C.L.5
Antoine, D.J.6
Spencer, D.M.7
Kishimoto, T.K.8
Pisetsky, D.S.9
Park, B.K.10
Watkins, P.B.11
-
6
-
-
84884207257
-
Sensitivity of species to chemicals: dose-response characteristics for various test types (LC(50), LR(50) and LD(50)) and modes of action
-
Hendriks A.J., Awkerman J.A., de Zwart D., Huijbregts M.A. Sensitivity of species to chemicals: dose-response characteristics for various test types (LC(50), LR(50) and LD(50)) and modes of action. Ecotoxicol. Environ. Saf. 2013, 97:10-16. 10.1016/j.ecoenv.2013.06.020.
-
(2013)
Ecotoxicol. Environ. Saf.
, vol.97
, pp. 10-16
-
-
Hendriks, A.J.1
Awkerman, J.A.2
de Zwart, D.3
Huijbregts, M.A.4
-
7
-
-
77649205818
-
Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR)
-
Kroh E.M., Parkin R.K., Mitchell P.S., Tewari M. Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR). Methods 2010, 50(4):298-301. 10.1016/j.ymeth.2010.01.032.
-
(2010)
Methods
, vol.50
, Issue.4
, pp. 298-301
-
-
Kroh, E.M.1
Parkin, R.K.2
Mitchell, P.S.3
Tewari, M.4
-
8
-
-
0037197803
-
Identification of tissue-specific microRNAs from mouse
-
Lagos-Quintana M., Rauhut R., Yalcin A., Meyer J., Lendeckel W., Tuschl T. Identification of tissue-specific microRNAs from mouse. Curr. Biol. 2002, 12(9):735-739.
-
(2002)
Curr. Biol.
, vol.12
, Issue.9
, pp. 735-739
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Yalcin, A.3
Meyer, J.4
Lendeckel, W.5
Tuschl, T.6
-
9
-
-
0036066905
-
Advantages of glutamate dehydrogenase as a blood biomarker of acute hepatic injury in rats
-
O'Brien P.J., Slaughter M.R., Polley S.R., Kramer K. Advantages of glutamate dehydrogenase as a blood biomarker of acute hepatic injury in rats. Lab Anim. 2002, 36(3):313-321.
-
(2002)
Lab Anim.
, vol.36
, Issue.3
, pp. 313-321
-
-
O'Brien, P.J.1
Slaughter, M.R.2
Polley, S.R.3
Kramer, K.4
-
10
-
-
39649094514
-
The current state of serum biomarkers of hepatotoxicity
-
Ozer J., Ratner M., Shaw M., Bailey W., Schomaker S. The current state of serum biomarkers of hepatotoxicity. Toxicology 2008, 245(3):194-205. 10.1016/j.tox.2007.11.021.
-
(2008)
Toxicology
, vol.245
, Issue.3
, pp. 194-205
-
-
Ozer, J.1
Ratner, M.2
Shaw, M.3
Bailey, W.4
Schomaker, S.5
-
11
-
-
0023833030
-
Glutamate dehydrogenase: biochemical and clinical aspects of an interesting enzyme
-
Schmidt E.S., Schmidt F.W. Glutamate dehydrogenase: biochemical and clinical aspects of an interesting enzyme. Clin. Chim. Acta 1988, 173(1):43-55.
-
(1988)
Clin. Chim. Acta
, vol.173
, Issue.1
, pp. 43-55
-
-
Schmidt, E.S.1
Schmidt, F.W.2
-
12
-
-
84865404634
-
Serum microRNA biomarkers for drug-induced liver injury
-
Starkey Lewis P.J., Merz M., Couttet P., Grenet O., Dear J., Antoine D.J., Goldring C., Park B.K., Moggs J.G. Serum microRNA biomarkers for drug-induced liver injury. Clin. Pharmacol. Ther. 2012, 92(3):291-293. 10.1038/clpt.2012.101.
-
(2012)
Clin. Pharmacol. Ther.
, vol.92
, Issue.3
, pp. 291-293
-
-
Starkey, L.P.J.1
Merz, M.2
Couttet, P.3
Grenet, O.4
Dear, J.5
Antoine, D.J.6
Goldring, C.7
Park, B.K.8
Moggs, J.G.9
-
13
-
-
84893665111
-
Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts
-
Thulin P., Nordahl G., Gry M., Yimer G., Aklillu E., Makonnen E., Aderaye G., Lindquist L., Mattsson C.M., Ekblom B., Antoine D.J., Park B.K., Linder S., Harrill A.H., Watkins P.B., Glinghammar B., Schuppe-Koistinen I. Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts. Liver Int 2013, 10.1111/liv.12322.
-
(2013)
Liver Int
-
-
Thulin, P.1
Nordahl, G.2
Gry, M.3
Yimer, G.4
Aklillu, E.5
Makonnen, E.6
Aderaye, G.7
Lindquist, L.8
Mattsson, C.M.9
Ekblom, B.10
Antoine, D.J.11
Park, B.K.12
Linder, S.13
Harrill, A.H.14
Watkins, P.B.15
Glinghammar, B.16
Schuppe-Koistinen, I.17
-
14
-
-
84867816814
-
Dogs are more sensitive to antagonists of inhibitor of apoptosis proteins than rats and humans: a translational toxicokinetic/toxicodynamic analysis
-
Wong H., Budha N.R., West K., Blackwood E., Ware J.A., Yu R., Darbonne W.C., Gould S.E., Steigerwalt R., Erickson R., Hop C.E., LoRusso P., Eckhardt S.G., Wagner A., Chan I.T., Mamounas M., Flygare J.A., Fairbrother W.J. Dogs are more sensitive to antagonists of inhibitor of apoptosis proteins than rats and humans: a translational toxicokinetic/toxicodynamic analysis. Toxicol. Sci. 2012, 130(1):205-213. 10.1093/toxsci/kfs235.
-
(2012)
Toxicol. Sci.
, vol.130
, Issue.1
, pp. 205-213
-
-
Wong, H.1
Budha, N.R.2
West, K.3
Blackwood, E.4
Ware, J.A.5
Yu, R.6
Darbonne, W.C.7
Gould, S.E.8
Steigerwalt, R.9
Erickson, R.10
Hop, C.E.11
LoRusso, P.12
Eckhardt, S.G.13
Wagner, A.14
Chan, I.T.15
Mamounas, M.16
Flygare, J.A.17
Fairbrother, W.J.18
-
15
-
-
78649837734
-
Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases
-
Zhang Y., Jia Y., Zheng R., Guo Y., Wang Y., Guo H., Fei M., Sun S. Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases. Clin. Chem. 2010, 56(12):1830-1838. 10.1373/clinchem.2010.147850.
-
(2010)
Clin. Chem.
, vol.56
, Issue.12
, pp. 1830-1838
-
-
Zhang, Y.1
Jia, Y.2
Zheng, R.3
Guo, Y.4
Wang, Y.5
Guo, H.6
Fei, M.7
Sun, S.8
-
16
-
-
84867835551
-
Serum levels of microRNAs can specifically predict liver injury of chronic hepatitis B
-
Zhang H., Li Q.Y., Guo Z.Z., Guan Y., Du J., Lu Y.Y., Hu Y.Y., Liu P., Huang S., Su S.B. Serum levels of microRNAs can specifically predict liver injury of chronic hepatitis B. World J. Gastroenterol. 2012, 18(37):5188-5196. 10.3748/wjg.v18.i37.5188.
-
(2012)
World J. Gastroenterol.
, vol.18
, Issue.37
, pp. 5188-5196
-
-
Zhang, H.1
Li, Q.Y.2
Guo, Z.Z.3
Guan, Y.4
Du, J.5
Lu, Y.Y.6
Hu, Y.Y.7
Liu, P.8
Huang, S.9
Su, S.B.10
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