The altered expression profile of microRNAs in cardiopulmonary bypass canine models and the effects of mir-499 on myocardial ischemic reperfusion injury

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Qin, Han ^a   Chen, Guang xian ^a   Liang, Meng ya ^a   Rong, Jian ^a   Yao, Jian ping ^a   Liu, Hai ^a   Wu, Zhong kai ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cardiopulmonary bypass; Ischemia reperfusion injury; MicroRNA; Mir 499

Indexed keywords

CREATINE KINASE MB; MICRORNA; MICRORNA 499; TROPONIN T; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CLAMPING; ARTICLE; CARDIOPLEGIA; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; CORRELATION ANALYSIS; DOG; DRUG TARGETING; FEMALE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE DP-DT; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MALE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN HEART SURGERY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; ANIMAL; BLOOD; DISEASE MODEL; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; HEMODYNAMICS; METABOLISM; PATHOPHYSIOLOGY; REPRODUCIBILITY;

ANIMALS; BIOLOGICAL MARKERS; CARDIOPULMONARY BYPASS; CREATINE KINASE, MB FORM; DISEASE MODELS, ANIMAL; DOGS; FEMALE; GENE EXPRESSION PROFILING; HEMODYNAMICS; MALE; MICRORNAS; MYOCARDIAL REPERFUSION INJURY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REPRODUCIBILITY OF RESULTS; TIME FACTORS; TROPONIN T;

EID: 84879123880     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-154     Document Type: Article

References (48)

1. Ambros V. The functions of animal microRNAs. Nature 2004, 431(7006):350-355. 10.1038/nature02871, 15372042.
2. Bala S, Tilahun Y, Taha O, Alao H, Kodys K, Catalano D, Szabo G. Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection. J Transl Med 2012, 10:151. 10.1186/1479-5876-10-151, 3477071, 22846613.
3. Callis TE, Wang DZ. Taking microRNAs to heart. Trends Mol Med 2008, 14(6):254-260. 10.1016/j.molmed.2008.03.006, 18457996.
4. Hu S, Huang M, Li Z, Jia F, Ghosh Z, Lijkwan MA, Fasanaro P, Sun N, Wang X, Martelli F, et al. MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation 2010, 122(11 Suppl):S124-S131. 2952325, 20837903.
5. Belevych AE, Sansom SE, Terentyeva R, Ho HT, Nishijima Y, Martin MM, Jindal HK, Rochira JA, Kunitomo Y, Abdellatif M, et al. MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex. PLoS One 2011, 6(12):e28324. 10.1371/journal.pone.0028324, 3232211, 22163007.
6. Wang C, Wang S, Zhao P, Wang X, Wang J, Wang Y, Song L, Zou Y, Hui R. MiR-221 promotes cardiac hypertrophy in vitro through the modulation of p27 expression. J Cell Biochem 2012, 113(6):2040-2046. 10.1002/jcb.24075, 22275134.
7. Cooley N, Cowley MJ, Lin RC, Marasco S, Wong C, Kaye DM, Dart AM, Woodcock EA. Influence of atrial fibrillation on microRNA expression profiles in left and right atria from patients with valvular heart disease. Physiol Genomics 2012, 44(3):211-219. 10.1152/physiolgenomics.00111.2011, 22147268.
8. Shi B, Guo Y, Wang J, Gao W. Altered expression of microRNAs in the myocardium of rats with acute myocardial infarction. BMC Cardiovasc Disord 2010, 10:11. 10.1186/1471-2261-10-11, 2844352, 20187981.
9. Fichtlscherer S, De Rosa S, Fox H, Schwietz T, Fischer A, Liebetrau C, Weber M, Hamm CW, Roxe T, Muller-Ardogan M, et al. Circulating microRNAs in patients with coronary artery disease. Circ Res 2010, 107(5):677-684. 10.1161/CIRCRESAHA.109.215566, 20595655.
10. Hullinger TG, Montgomery RL, Seto AG, Dickinson BA, Semus HM, Lynch JM, Dalby CM, Robinson K, Stack C, Latimer PA, et al. Inhibition of miR-15 protects against cardiac ischemic injury. Circ Res 2012, 110(1):71-81. 10.1161/CIRCRESAHA.111.244442, 3354618, 22052914.
11. Lu Y, Zhang Y, Shan H, Pan Z, Li X, Li B, Xu C, Zhang B, Zhang F, Dong D, et al. MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection. Cardiovasc Res 2009, 84(3):434-441. 10.1093/cvr/cvp232, 19581315.
12. Fasanaro P, Greco S, Ivan M, Capogrossi MC, Martelli F. microRNA: emerging therapeutic targets in acute ischemic diseases. Pharmacol Ther 2010, 125(1):92-104. 10.1016/j.pharmthera.2009.10.003, 19896977.
13. Bostjancic E, Zidar N, Stajer D, Glavac D. MicroRNAs miR-1, miR-133a, miR-133b and miR-208 are dysregulated in human myocardial infarction. Cardiology 2010, 115(3):163-169. 10.1159/000268088, 20029200.
14. Rong J, Ye S, Wu ZK, Chen GX, Liang MY, Liu H, Zhang JX, Huang WM. Controlled oxygen reperfusion protects the lung against early ischemia-reperfusion injury in cardiopulmonary bypasses by downregulating high mobility group box 1. Exp Lung Res 2011, 38(4):183-191.
15. Gao X, Gulari E, Zhou X. In situ synthesis of oligonucleotide microarrays. Biopolymers 2004, 73(5):579-596. 10.1002/bip.20005, 15048782.
16. Zhu Q, Hong A, Sheng N, Zhang X, Matejko A, Jun KY, Srivannavit O, Gulari E, Gao X, Zhou X. microParaflo biochip for nucleic acid and protein analysis. Methods Mol Biol 2007, 382:287-312. 10.1007/978-1-59745-304-2_19, 18220239.
17. Bolstad BM, Irizarry RA, Astrand M, Speed TP. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 2003, 19(2):185-193. 10.1093/bioinformatics/19.2.185, 12538238.
18. Boggs RM, Wright ZM, Stickney MJ, Porter WW, Murphy KE. MicroRNA expression in canine mammary cancer. Mamm Genome 2008, 19(7-8):561-569.
19. Mortarino M, Gioia G, Gelain ME, Albonico F, Roccabianca P, Ferri E, Comazzi S. Identification of suitable endogenous controls and differentially expressed microRNAs in canine fresh-frozen and FFPE lymphoma samples. Leuk Res 2010, 34(8):1070-1077. 10.1016/j.leukres.2009.10.023, 19945163.
20. Wang X, Zhang X, Ren XP, Chen J, Liu H, Yang J, Medvedovic M, Hu Z, Fan GC. MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injury. Circulation 2010, 122(13):1308-1318. 10.1161/CIRCULATIONAHA.110.964684, 2956502, 20837890.
21. D'Alessandra Y, Pompilio G, Capogrossi MC. MicroRNAs and myocardial infarction. Curr Opin Cardiol 2012, 27(3):228-235. 10.1097/HCO.0b013e3283522052, 22476028.
22. Wang JX, Jiao JQ, Li Q, Long B, Wang K, Liu JP, Li YR, Li PF. miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1. Nat Med 2011, 17(1):71-78. 10.1038/nm.2282, 21186368.
23. Elyakim E, Sitbon E, Faerman A, Tabak S, Montia E, Belanis L, Dov A, Marcusson EG, Bennett CF, Chajut A, et al. hsa-miR-191 is a candidate oncogene target for hepatocellular carcinoma therapy. Cancer Res 2010, 70(20):8077-8087. 10.1158/0008-5472.CAN-10-1313, 20924108.
24. Xu XD, Song XW, Li Q, Wang GK, Jing Q, Qin YW. Attenuation of microRNA-22 derepressed PTEN to effectively protect rat cardiomyocytes from hypertrophy. J Cell Physiol 2012, 227(4):1391-1398. 10.1002/jcp.22852, 21618527.
25. Li J, Donath S, Li Y, Qin D, Prabhakar BS, Li P. miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway. PLoS Genet 2010, 6(1):e1000795. 10.1371/journal.pgen.1000795, 2793031, 20062521.
26. Qian L, Van Laake LW, Huang Y, Liu S, Wendland MF, Srivastava D. miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. J Exp Med 2011, 208(3):549-560. 10.1084/jem.20101547, 3058576, 21383058.
27. Godlewski J, Nowicki MO, Bronisz A, Nuovo G, Palatini J, De Lay M, Van Brocklyn J, Ostrowski MC, Chiocca EA, Lawler SE. MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. Mol Cell 2010, 37(5):620-632. 10.1016/j.molcel.2010.02.018, 3125113, 20227367.
28. Kulshreshtha R, Ferracin M, Wojcik SE, Garzon R, Alder H, Agosto-Perez FJ, Davuluri R, Liu CG, Croce CM, Negrini M, et al. A microRNA signature of hypoxia. Mol Cell Biol 2007, 27(5):1859-1867. 10.1128/MCB.01395-06, 1820461, 17194750.
29. Kikkawa N, Hanazawa T, Fujimura L, Nohata N, Suzuki H, Chazono H, Sakurai D, Horiguchi S, Okamoto Y, Seki N. miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC). Br J Cancer 2010, 103(6):877-884. 10.1038/sj.bjc.6605811, 2966617, 20700123.
30. Buechner J, Tomte E, Haug BH, Henriksen JR, Lokke C, Flaegstad T, Einvik C. Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma. Br J Cancer 2011, 105(2):296-303. 10.1038/bjc.2011.220, 3142803, 21654684.
31. Zhu H, Fan GC. Extracellular/circulating microRNAs and their potential role in cardiovascular disease. Am J Cardiovasc Dis 2011, 1(2):138-149. 3207246,3207246, 22059153.
32. Yu S, Li G. MicroRNA expression and function in cardiac ischemic injury. J Cardiovasc Transl Res 2010, 3(3):241-245. 10.1007/s12265-010-9168-8, 2882299, 20535240.
33. Xu C, Lu Y, Pan Z, Chu W, Luo X, Lin H, Xiao J, Shan H, Wang Z, Yang B. The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J Cell Sci 2007, 120(Pt 17):3045-3052.
34. Zhou X, Mao A, Wang X, Duan X, Yao Y, Zhang C. Urine and serum microRNA-1 as novel biomarkers for myocardial injury in open-heart surgeries with cardiopulmonary bypass. PLoS One 2013, 8(4):e62245. 10.1371/journal.pone.0062245, 3632512, 23630629.
35. Malmberg M, Parkka J, Vahasilta T, Saraste A, Laitio T, Kiss J, Latva-Hirvela J, Saukko P, Savunen T. Cardiomyocyte apoptosis after cardioplegic ischemia: comparison to unprotected regional ischemia-reperfusion. Eur Surg Res 2011, 46(1):19-25. 10.1159/000321875, 21150207.
36. Valen G. The basic biology of apoptosis and its implications for cardiac function and viability. Ann Thorac Surg 2003, 75(2):S656-S660. 10.1016/S0003-4975(02)04687-8, 12607708.
37. Kinoshita T, Asai T. Preservation of myocardium during coronary artery bypass surgery. Curr Cardiol Rep 2012, 14(4):418-423. 10.1007/s11886-012-0271-0, 22528557.
38. Kloosterman WP, Steiner FA, Berezikov E, de Bruijn E, van de Belt J, Verheul M, Cuppen E, Plasterk RH. Cloning and expression of new microRNAs from zebrafish. Nucleic Acids Res 2006, 34(9):2558-2569. 10.1093/nar/gkl278, 3303176, 16698962.
39. Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007, 129(7):1401-1414. 10.1016/j.cell.2007.04.040, 2681231, 17604727.
40. Liang Y, Ridzon D, Wong L, Chen C. Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 2007, 8:166. 10.1186/1471-2164-8-166, 1904203, 17565689.
41. Reddy AM, Zheng Y, Jagadeeswaran G, Macmil SL, Graham WB, Roe BA, Desilva U, Zhang W, Sunkar R. Cloning, characterization and expression analysis of porcine microRNAs. BMC Genomics 2009, 10:65. 10.1186/1471-2164-10-65, 2644714, 19196471.
42. Kim HJ, Cui XS, Kim EJ, Kim WJ, Kim NH. New porcine microRNA genes found by homology search. Genome 2006, 49(10):1283-1286. 10.1139/g06-120, 17213910.
43. van Rooij E, Quiat D, Johnson BA, Sutherland LB, Qi X, Richardson JA, Kelm RJ, Olson EN. A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev Cell 2009, 17(5):662-673. 10.1016/j.devcel.2009.10.013, 2796371, 19922871.
44. Yeung F, Chung E, Guess MG, Bell ML, Leinwand LA. Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Res 2012, 40(15):7303-7318. 10.1093/nar/gks466, 3424578, 22638570.
45. De Rosa S, Fichtlscherer S, Lehmann R, Assmus B, Dimmeler S, Zeiher AM. Transcoronary concentration gradients of circulating microRNAs. Circulation 2011, 124(18):1936-1944. 10.1161/CIRCULATIONAHA.111.037572, 21969012.
46. Kovacevic M, Simic O, Jonjic N, Stifter S. Apoptosis and cardiopulmonary bypass. J Card Surg 2007, 22(2):129-134. 10.1111/j.1540-8191.2006.00355.x, 17338746.
47. Widera C, Gupta SK, Lorenzen JM, Bang C, Bauersachs J, Bethmann K, Kempf T, Wollert KC, Thum T. Diagnostic and prognostic impact of six circulating microRNAs in acute coronary syndrome. J Mol Cell Cardiol 2011, 51(5):872-875. 10.1016/j.yjmcc.2011.07.011, 21806992.
48. Adachi T, Nakanishi M, Otsuka Y, Nishimura K, Hirokawa G, Goto Y, Nonogi H, Iwai N. Plasma microRNA 499 as a biomarker of acute myocardial infarction. Clin Chem 2010, 56(7):1183-1185. 10.1373/clinchem.2010.144121, 20395621.