Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 311, Issue 1, 2016, Pages L124-L134

  Nozik Grayck, Eva ^a,b   Woods, Crystal ^a,b   Stearman, Robert S ^f   Venkataraman, Sujatha ^a   Ferguson, Bradley S ^c   Swain, Kalin ^a,b   Bowler, Russell P ^d   Geraci, Mark W ^f   Ihida Stansbury, Kaori ^e   Stenmark, Kurt R ^a,b,c   McKinsey, Timothy A ^c   Domann, Frederick E ^g  

^a University of Colorado Denver and Children s Hospital Colorado   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f INDIANA UNIVERSITY   (United States)

^g UNIVERSITY OF IOWA   (United States)

Author keywords

DNA methylation; Extracellular superoxide dismutase; Histone deacetylation; Idiopathic pulmonary arterial hypertension

Indexed keywords

EXTRACELLULAR SUPEROXIDE DISMUTASE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE 3; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; HISTONE; HISTONE DEACETYLASE INHIBITOR; SOD3 PROTEIN, HUMAN; SUPEROXIDE DISMUTASE;

ADULT; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; FEMALE; HISTONE DEACETYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY SMOOTH MUSCLE CELL; PULMONARY HYPERTENSION; ACETYLATION; ANIMAL; CELL CULTURE; ENZYME REPRESSION; ENZYMOLOGY; GENE EXPRESSION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PROMOTER REGION; PROTEIN PROCESSING; RAT; SMOOTH MUSCLE CELL; VASCULAR SMOOTH MUSCLE; YOUNG ADULT;

ACETYLATION; ADULT; ANIMALS; CELLS, CULTURED; ENZYME REPRESSION; FEMALE; GENE EXPRESSION; HISTONE DEACETYLASE INHIBITORS; HISTONES; HUMANS; HYPERTENSION, PULMONARY; MALE; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; SUPEROXIDE DISMUTASE; YOUNG ADULT;

EID: 84982177978     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00263.2015     Document Type: Article

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