The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome

Free Radical Biology and Medicine

Volumn 99, Issue , 2016, Pages 153-166

  Reeg, Sandra ^a   Jung, Tobias ^a,b   Castro, José P ^a,b   Davies, Kelvin J A ^c   Henze, Andrea ^d   Grune, Tilman ^a,b  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UNIVERSITY OF POTSDAM   (Germany)

Author keywords

Chaperone; HSP70; Proteasome; Protein oxidation

Indexed keywords

HEAT SHOCK PROTEIN 70; PROTEASOME; PROTEIN; ATP DEPENDENT 26S PROTEASE; GREEN FLUORESCENT PROTEIN; HYDROGEN PEROXIDE; NERVE PROTEIN; PROTEIN AGGREGATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CELL VIABILITY; CONTROLLED STUDY; DISSOCIATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENETICS; HIPPOCAMPUS; METABOLISM; NERVE CELL; OXIDATION REDUCTION REACTION; REPORTER GENE;

ANIMALS; CELL LINE; CELL SURVIVAL; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; HSP70 HEAT-SHOCK PROTEINS; HYDROGEN PEROXIDE; MALE; MICE; NERVE TISSUE PROTEINS; NEURONS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN AGGREGATES; PROTEOLYSIS;

EID: 84982103066     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2016.08.002     Document Type: Article

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