메뉴 건너뛰기




Volumn 47, Issue 6, 2015, Pages 2045-2056

Inhibition of caspase-9 by oridonin, a diterpenoid isolated from Rabdosia rubescens, augments apoptosis in human laryngeal cancer cells

Author keywords

Apoptosis; Autophagy; Caspase 9; Oridonin; Reactive oxygen species

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; DEATH RECEPTOR; FAS ASSOCIATED DEATH DOMAIN PROTEIN; ORIDONIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; ANTINEOPLASTIC AGENT; CASP9 PROTEIN, HUMAN; KAURANE DERIVATIVE;

EID: 84982076524     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2015.3186     Document Type: Article
Times cited : (34)

References (50)
  • 1
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN and Korsmeyer SJ: Cell death: Critical control points. Cell 116:205-219, 2004.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 2
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan J and Yankner BA: Apoptosis in the nervous system. Nature 407:802-809, 2000.
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 3
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D and Weinberg RA: The hallmarks of cancer. Cell 100:57-70, 2000.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 0037365968 scopus 로고    scopus 로고
    • Specificity of a third kind: Reactive oxygen and nitrogen intermediates in cell signaling
    • Nathan C: Specificity of a third kind: Reactive oxygen and nitrogen intermediates in cell signaling. J Clin Invest 111:769-778, 2003.
    • (2003) J Clin Invest , vol.111 , pp. 769-778
    • Nathan, C.1
  • 6
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • Pelicano H, Carney D and Huang P: ROS stress in cancer cells and therapeutic implications. Drug Resist Updat 7:97-110, 2004.
    • (2004) Drug Resist Updat , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 7
    • 0036463736 scopus 로고    scopus 로고
    • Autophagy in the eukaryotic cell
    • Reggiori F and Klionsky DJ: Autophagy in the eukaryotic cell. Eukaryot Cell 1:11-21, 2002.
    • (2002) Eukaryot Cell , vol.1 , pp. 11-21
    • Reggiori, F.1    Klionsky, D.J.2
  • 9
    • 37549056216 scopus 로고    scopus 로고
    • The roles of therapy-induced autophagy and necrosis in cancer treatment
    • Amaravadi RK and Thompson CB: The roles of therapy-induced autophagy and necrosis in cancer treatment. Clin Cancer Res 13:7271-7279, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 7271-7279
    • Amaravadi, R.K.1    Thompson, C.B.2
  • 10
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM and Klionsky DJ: Autophagy fights disease through cellular self-digestion. Nature 451:1069-1075, 2008.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 13
    • 84864957283 scopus 로고    scopus 로고
    • Emerging glycolysis targeting and drug discovery from Chinese medicine in cancer therapy
    • Wang Z, Wang N, Chen J and Shen J: Emerging glycolysis targeting and drug discovery from Chinese medicine in cancer therapy. Evid Based Complement Alternat Med 2012:873175, 2012.
    • (2012) Evid Based Complement Alternat Med , vol.2012 , pp. 873175
    • Wang, Z.1    Wang, N.2    Chen, J.3    Shen, J.4
  • 14
    • 84867573635 scopus 로고    scopus 로고
    • Optimisation of an ultrasound-assisted extraction followed by RP-HPLC separation for the simultaneous determination of oleanolic acid, ursolic acid and oridonin content in Rabdosia rubescens
    • Yang YC, Wei MC and Huang TC: Optimisation of an ultrasound-assisted extraction followed by RP-HPLC separation for the simultaneous determination of oleanolic acid, ursolic acid and oridonin content in Rabdosia rubescens. Phytochem Anal 23:627-636, 2012.
    • (2012) Phytochem Anal , vol.23 , pp. 627-636
    • Yang, Y.C.1    Wei, M.C.2    Huang, T.C.3
  • 16
    • 50149087699 scopus 로고    scopus 로고
    • Reactive oxygen species mediate oridonin-induced HepG2 apoptosis through p53, MAPK, and mitochondrial signaling pathways
    • Huang J, Wu L, Tashiro S, Onodera S and Ikejima T: Reactive oxygen species mediate oridonin-induced HepG2 apoptosis through p53, MAPK, and mitochondrial signaling pathways. J Pharmacol Sci 107:370-379, 2008.
    • (2008) J Pharmacol Sci , vol.107 , pp. 370-379
    • Huang, J.1    Wu, L.2    Tashiro, S.3    Onodera, S.4    Ikejima, T.5
  • 17
    • 77954071961 scopus 로고    scopus 로고
    • Induction of G (2)/m phase arrest and apoptosis by oridonin in human laryngeal carcinoma cells
    • Kang N, Zhang JH, Qiu F, Chen S, Tashiro S, Onodera S and Ikejima T: Induction of G (2)/m phase arrest and apoptosis by oridonin in human laryngeal carcinoma cells. J Nat Prod 73:1058-1063, 2010.
    • (2010) J Nat Prod , vol.73 , pp. 1058-1063
    • Kang, N.1    Zhang, J.H.2    Qiu, F.3    Chen, S.4    Tashiro, S.5    Onodera, S.6    Ikejima, T.7
  • 18
    • 52949092696 scopus 로고    scopus 로고
    • Caspase inhibition augmented oridonin-induced cell death in murine fibrosarcoma l929 by enhancing reactive oxygen species generation
    • Wu JN, Huang J, Yang J, Tashiro S, Onodera S and Ikejima T: Caspase inhibition augmented oridonin-induced cell death in murine fibrosarcoma l929 by enhancing reactive oxygen species generation. J Pharmacol Sci 108:32-39, 2008.
    • (2008) J Pharmacol Sci , vol.108 , pp. 32-39
    • Wu, J.N.1    Huang, J.2    Yang, J.3    Tashiro, S.4    Onodera, S.5    Ikejima, T.6
  • 19
    • 7244243900 scopus 로고    scopus 로고
    • Enhancement of stress-induced apoptosis in B-lineage cells by caspase-9 inhibitor
    • Shah N, Asch RJ, Lysholm AS and Lebien TW: Enhancement of stress-induced apoptosis in B-lineage cells by caspase-9 inhibitor. Blood 104:2873-2878, 2004.
    • (2004) Blood , vol.104 , pp. 2873-2878
    • Shah, N.1    Asch, R.J.2    Lysholm, A.S.3    Lebien, T.W.4
  • 20
    • 77953359873 scopus 로고    scopus 로고
    • Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways
    • Kang N, Zhang JH, Qiu F, Tashiro S, Onodera S and Ikejima T: Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways. Cancer Lett 294:147-158, 2010.
    • (2010) Cancer Lett , vol.294 , pp. 147-158
    • Kang, N.1    Zhang, J.H.2    Qiu, F.3    Tashiro, S.4    Onodera, S.5    Ikejima, T.6
  • 21
    • 33644526582 scopus 로고    scopus 로고
    • Isolation and purification of oridonin from Rabdosia rubescens using upright counter-current chromatography
    • Lu Y, Sun C and Pan Y: Isolation and purification of oridonin from Rabdosia rubescens using upright counter-current chromatography. J Sep. Sci 29:314-318, 2006.
    • (2006) J Sep. Sci , vol.29 , pp. 314-318
    • Lu, Y.1    Sun, C.2    Pan, Y.3
  • 25
    • 47749110951 scopus 로고    scopus 로고
    • Inhibition of insulin-like growth factor 1 receptor signaling enhanced silibinin-induced activation of death receptor and mitochondrial apoptotic pathways in human breast cancer MCF-7 cells
    • Wang HJ, Tashiro S, Onodera S and Ikejima T: Inhibition of insulin-like growth factor 1 receptor signaling enhanced silibinin-induced activation of death receptor and mitochondrial apoptotic pathways in human breast cancer MCF-7 cells. J Pharmacol Sci 107:260-269, 2008.
    • (2008) J Pharmacol Sci , vol.107 , pp. 260-269
    • Wang, H.J.1    Tashiro, S.2    Onodera, S.3    Ikejima, T.4
  • 26
    • 33748165596 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer cells: Live by the sword, die by the sword
    • Schumacker PT: Reactive oxygen species in cancer cells: Live by the sword, die by the sword. Cancer Cell 10:175-176, 2006.
    • (2006) Cancer Cell , vol.10 , pp. 175-176
    • Schumacker, P.T.1
  • 28
    • 33644766960 scopus 로고    scopus 로고
    • Relationship between levels of oxidative DNA damage, lipid peroxidation and mitochondrial membrane potential in young and old F344 rats
    • Wong YT, Ruan R and Tay FE: Relationship between levels of oxidative DNA damage, lipid peroxidation and mitochondrial membrane potential in young and old F344 rats. Free Radic Res 40:393-402, 2006.
    • (2006) Free Radic Res , vol.40 , pp. 393-402
    • Wong, Y.T.1    Ruan, R.2    Tay, F.E.3
  • 29
    • 0033056950 scopus 로고    scopus 로고
    • Functional differences of two forms of the inhibitor of caspase-activated DNase, ICAD-L, and ICAD-S
    • Sakahira H, Enari M and Nagata S: Functional differences of two forms of the inhibitor of caspase-activated DNase, ICAD-L, and ICAD-S. J Biol Chem 274:15740-15744, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 15740-15744
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 31
    • 0034105784 scopus 로고    scopus 로고
    • Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes
    • Cain K, Bratton SB, Langlais C, Walker G, Brown DG, Sun XM and Cohen GM: Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes. J Biol Chem 275:6067-6070, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 6067-6070
    • Cain, K.1    Bratton, S.B.2    Langlais, C.3    Walker, G.4    Brown, D.G.5    Sun, X.M.6    Cohen, G.M.7
  • 32
    • 0344348821 scopus 로고    scopus 로고
    • Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
    • Hu Y, Benedict MA, Ding L and Núñez G: Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. EMBO J 18:3586-3595, 1999.
    • (1999) EMBO J , vol.18 , pp. 3586-3595
    • Hu, Y.1    Benedict, M.A.2    Ding, L.3    Núñez, G.4
  • 34
    • 0036468550 scopus 로고    scopus 로고
    • Dysfunctional apoptosome activation in ovarian cancer: Implications for chemoresistance
    • Liu JR, Opipari AW, Tan L, Jiang Y, Zhang Y, Tang H and Nuñez G: Dysfunctional apoptosome activation in ovarian cancer: Implications for chemoresistance. Cancer Res 62:924-931, 2002.
    • (2002) Cancer Res , vol.62 , pp. 924-931
    • Liu, J.R.1    Opipari, A.W.2    Tan, L.3    Jiang, Y.4    Zhang, Y.5    Tang, H.6    Nuñez, G.7
  • 35
    • 0032777463 scopus 로고    scopus 로고
    • Anticancer drug design based on plant-derived natural products
    • Lee KH: Anticancer drug design based on plant-derived natural products. J Biomed Sci 6:236-250, 1999.
    • (1999) J Biomed Sci , vol.6 , pp. 236-250
    • Lee, K.H.1
  • 36
    • 0035078341 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) mediates the mitochondrial-dependent apoptosis induced by transforming growth factor (beta) in fetal hepatocytes
    • Herrera B, Alvarez AM, Sánchez A, Fernández M, Roncero C, Benito M and Fabregat I: Reactive oxygen species (ROS) mediates the mitochondrial-dependent apoptosis induced by transforming growth factor (beta) in fetal hepatocytes. FASEB J 15:741-751, 2001.
    • (2001) FASEB J , vol.15 , pp. 741-751
    • Herrera, B.1    Alvarez, A.M.2    Sánchez, A.3    Fernández, M.4    Roncero, C.5    Benito, M.6    Fabregat, I.7
  • 37
    • 0034874036 scopus 로고    scopus 로고
    • Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor beta in rat fetal hepatocytes
    • Herrera B, Fernández M, Alvarez AM, Roncero C, Benito M, Gil J and Fabregat I: Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor beta in rat fetal hepatocytes. Hepatology 34:548-556, 2001.
    • (2001) Hepatology , vol.34 , pp. 548-556
    • Herrera, B.1    Fernández, M.2    Alvarez, A.M.3    Roncero, C.4    Benito, M.5    Gil, J.6    Fabregat, I.7
  • 38
    • 0038297002 scopus 로고    scopus 로고
    • The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction
    • Chen Q, Chai YC, Mazumder S, Jiang C, Macklis RM, Chisolm GM and Almasan A: The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction. Cell Death Differ 10:323-334, 2003.
    • (2003) Cell Death Differ , vol.10 , pp. 323-334
    • Chen, Q.1    Chai, Y.C.2    Mazumder, S.3    Jiang, C.4    Macklis, R.M.5    Chisolm, G.M.6    Almasan, A.7
  • 39
    • 0034617449 scopus 로고    scopus 로고
    • Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis
    • Daugas E, Nochy D, Ravagnan L, Loeffler M, Susin SA, Zamzami N and Kroemer G: Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett 476:118-123, 2000.
    • (2000) FEBS Lett , vol.476 , pp. 118-123
    • Daugas, E.1    Nochy, D.2    Ravagnan, L.3    Loeffler, M.4    Susin, S.A.5    Zamzami, N.6    Kroemer, G.7
  • 41
    • 0033805296 scopus 로고    scopus 로고
    • Triggering and modulation of apoptosis by oxidative stress
    • Chandra J, Samali A and Orrenius S: Triggering and modulation of apoptosis by oxidative stress. Free Radic Biol Med 29:323-333, 2000.
    • (2000) Free Radic Biol Med , vol.29 , pp. 323-333
    • Chandra, J.1    Samali, A.2    Orrenius, S.3
  • 43
    • 78649251041 scopus 로고    scopus 로고
    • The in vitro cleavage of the hAtg proteins by cell death proteases
    • Norman JM, Cohen GM and Bampton ET: The in vitro cleavage of the hAtg proteins by cell death proteases. Autophagy 6:1042-1056, 2010.
    • (2010) Autophagy , vol.6 , pp. 1042-1056
    • Norman, J.M.1    Cohen, G.M.2    Bampton, E.T.3
  • 44
    • 84859480341 scopus 로고    scopus 로고
    • Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis
    • Young MM, Takahashi Y, Khan O, Park S, Hori T, Yun J, Sharma AK, Amin S, Hu CD, Zhang J, et al: Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. J Biol Chem 287:12455-12468, 2012.
    • (2012) J Biol Chem , vol.287 , pp. 12455-12468
    • Young, M.M.1    Takahashi, Y.2    Khan, O.3    Park, S.4    Hori, T.5    Yun, J.6    Sharma, A.K.7    Amin, S.8    Hu, C.D.9    Zhang, J.10
  • 45
    • 57749089665 scopus 로고    scopus 로고
    • Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells
    • Cho DH, Jo YK, Hwang JJ, Lee YM, Roh SA and Kim JC: Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells. Cancer Lett 274:95-100, 2009.
    • (2009) Cancer Lett , vol.274 , pp. 95-100
    • Cho, D.H.1    Jo, Y.K.2    Hwang, J.J.3    Lee, Y.M.4    Roh, S.A.5    Kim, J.C.6
  • 46
    • 34848845834 scopus 로고    scopus 로고
    • Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells
    • Wang ZH, Xu L, Duan ZL, Zeng LQ, Yan NH and Peng ZL: Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells. Gynecol Oncol 107:107-113, 2007.
    • (2007) Gynecol Oncol , vol.107 , pp. 107-113
    • Wang, Z.H.1    Xu, L.2    Duan, Z.L.3    Zeng, L.Q.4    Yan, N.H.5    Peng, Z.L.6
  • 47
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T and Thompson CB: Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120:237-248, 2005.
    • (2005) Cell , vol.120 , pp. 237-248
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3    Harris, M.H.4    Li, C.5    Lindsten, T.6    Thompson, C.B.7
  • 49
    • 0033573020 scopus 로고    scopus 로고
    • Caspase-9 and APAF-1 form an active holoenzyme
    • Rodriguez J and Lazebnik Y: Caspase-9 and APAF-1 form an active holoenzyme. Genes Dev 13:3179-3184, 1999.
    • (1999) Genes Dev , vol.13 , pp. 3179-3184
    • Rodriguez, J.1    Lazebnik, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.