Optimisation of an ultrasound-assisted extraction followed by RP-HPLC separation for the simultaneous determination of oleanolic acid, ursolic acid and oridonin content in Rabdosia rubescens

Phytochemical Analysis

Volumn 23, Issue 6, 2012, Pages 627-636

  Yang, Yu Chiao ^a   Wei, Ming Chi ^b   Huang, Ting Chia ^c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

HPLC; Isodon rubescens; oleanolic acid; oridonin; Rabdosia rubescens; ursolic acid

Indexed keywords

CARBOXYLIC ACIDS; GEOGRAPHICAL REGIONS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MEDICINE; ULTRASONIC APPLICATIONS;

BIOACTIVE COMPOUNDS; HPLC; HPLC METHOD; ISODON RUBESCEN; OLEANOLIC ACIDS; OPTIMISATIONS; ORIDONIN; RABDOSIUM RUBESCEN; ULTRASOUND-ASSISTED EXTRACTION; URSOLIC ACID;

EXTRACTION;

OLEANOLIC ACID; ORIDONIN; URSOLIC ACID;

ABSORPTION; ACCURACY; AQUEOUS SOLUTION; ARTICLE; CELL WALL; DRY WEIGHT; EXTRACTION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; NONHUMAN; PARTICLE SIZE; QUANTITATIVE ANALYSIS; RABDOSIA; RABDOSIA RUBESCENS; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLUBILITY; TEMPERATURE; ULTRASOUND ASSISTED EXTRACTION;

RABDOSIA RUBESCENS;

EID: 84867573635     PISSN: 09580344     EISSN: 10991565     Source Type: Journal    
DOI: 10.1002/pca.2365     Document Type: Article

References (25)

1. Büchele B, Zugmaier W, Simmet T,. 2003. Analysis of pentacyclic triterpenic acids from frankincense gum resins and related phytopharmaceuticals by high-performance liquid chromatography. Identification of lupeolic acid, a novel pentacyclic triterpene. J Chromatogr B Analyt Technol Biomed Life Sci 791: 21-30.
2. Claude B, Morin P, Lafosse M, Andre P,. 2004. Evaluation of apparent formation constants of pentacyclic triterpene acids complexes with derivatised beta- and gamma-cyclodextrins by reversed phase liquid chromatography. J Chromatogr A 1049: 37-42.
3. Hsu YL, Kuo PL, Lin CC,. 2004. Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells. Life Sci 75: 2303-2316.
4. Hu HZ, Yang YB, Xu XD, Shen HW, Shu YM, Ren Z, Li XM, Shen HM, Zeng HT,. 2007. Oridonin induces apoptosis via PI3K/Akt pathway in cervical carcinoma HeLa cell line. Acta Pharmacol Sin 28: 1819-1826.
5. Huang MT, Ho CT, Wang ZY, Ferraro T, Lou YR, Stauber K, Ma W, Georgiadis C, Laskin JD, Conney AH,. 1994. Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid. Cancer Res 54: 701-708.
6. Ikezoe T, Chen SS, Tong XJ, Heber D, Taguchi H, Koeffler HP,. 2003. Oridonin induces growth inhibition and apoptosis of a variety of human cancer cells. Int J Oncol 23: 1187-1193.
7. Jin H, Tan X, Liu X, Ding Y,. 2011. Downregulation of AP-1 gene expression is an initial event in the oridonin-mediated inhibition of colorectal cancer: studies in vitro and in vivo. J Gastroenterol Hepatol 26: 706-715.
8. Kang N, Zhang JH, Qiu F, Tashiro S, Onodera S, Ikejima T,. 2010. Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways. Cancer Lett 294: 147-158.
9. Li D, Wu LJ, Tashiro S, Onodera S, Ikejima T,. 2007. Oridonin inhibited the tyrosine kinase activity and induced apoptosis in human epidermoid carcinoma A431 cells. Biol Pharm Bull 30: 254-260.
10. Lu Y, Sun C, Liu R, Pan Y,. 2007. Effective two-dimensional counter-current chromatographic method for simultaneous isolation and purification of oridonin and ponicidin from the crude extract of Rabdosia rubescens. J Chromatogr A 1146: 125-130.
11. Mei Y, Xu J, Zhao J, Feng N, Liu Y, Wei L,. 2008. An HPLC method for determination of oridonin in rabbits using isopsoralen as an internal standard and its application to pharmacokinetic studies for oridonin-loaded nanoparticles. J Chromatogr B Analyt Technol Biomed Life Sci 869: 138-141.
12. Mirzajani F, Ghassempour A, Jalali-Heravi M, Mirjalili MH,. 2010. Optimisation of a microwave-assisted method for extracting withaferin A from Withania somnifera Dunal. using central composite design. Phytochem Anal 21: 544-549.
13. Ovesná Z, Kozics K, Slameňová D,. 2006. Protective effects of ursolic acid and oleanolic acid in leukemic cells. Mutat Res 600: 131-137.
14. Ramos AA, Pereira-Wilson C, Collins AR,. 2010. Protective effects of ursolic acid and luteolin against oxidative DNA damage include enhancement of DNA repair in Caco-2 cells. Mutat Res 692: 6-11.
15. Ren KK, Wang HZ, Xie LP, Chen DW, Liu X, Sun J, Nie YC, Zhang RQ,. 2006. The effects of oridonin on cell growth, cell cycle, cell migration and differentiation in melanoma cells. J Ethnopharmacol 103: 176-180.
16. Sun Y, Liu D, Chen J, Ye X, Yu D,. 2011. Effects of different factors of ultrasound treatment on the extraction yield of the all-trans-β-carotene from citrus peels. Ultrason Sonochem 18: 243-249.
17. Tang J, Zhao M, Wang Y, Kang G, Wu J, Zheng M, Peng S,. 2011. One single HPLC-PDA/(-)ESI-MS/MS analysis to simultaneously determine 30 components of the aqueous extract of Rabdosia rubescens. J Chromatogr B Analyt Technol Biomed Life Sci 879: 2783-2793.
18. Wang H, Ye Y, Pan SY, Zhu GY, Li YW, Fong DW, Yu ZL,. 2011. Proteomic identification of proteins involved in the anticancer activities of oridonin in HepG2 cells. Phytomedicine 18: 163-169.
19. Xia EQ, Yu YY, Xu XR, Deng GF, Guo YJ, Li HB,. 2012. Ultrasound-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum Ait. Ultrason Sonochem 19: 772-776.
20. Yan SL, Huang CY, Wu ST, Yin MC,. 2010. Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines. Toxicol In Vitro 24: 842-848.
21. Yim EK, Lee KH, Namkoong SE, Um SJ, Park JS,. 2006. Proteomic analysis of ursolic acid-induced apoptosis in cervical carcinoma cells. Cancer Lett 235: 209-220.
22. Zhai DD, Zhong JJ,. 2010. Simultaneous analysis of three bioactive compounds in Artemisia annua hairy root cultures by reversed-phase high-performance liquid chromatography-diode array detector. Phytochem Anal 21: 524-530.
23. Zhang S, Zu YG, Fu YJ, Luo M, Liu W, Li J, Efferth T,. 2010. Supercritical carbon dioxide extraction of seed oil from yellow horn (Xanthoceras sorbifolia Bunge.) and its anti-oxidant activity. Bioresour Technol 101: 2537-2544.
24. Zhang YX, Kong CZ, Wang HQ, Wang LH, Xu CL, Sun YH,. 2009. Phosphorylation of Bcl-2 and activation of caspase-3 via the c-Jun N-terminal kinase pathway in ursolic acid-induced DU145 cells apoptosis. Biochimie 91: 1173-1179.
25. Zhou C, Sheng Y, Zhao D, Wang Z, Tao J,. 2010. Variation of oleanolic and ursolic acid in the flesh of persimmon fruit among different cultivars. Molecules 15: 6580-6587.