메뉴 건너뛰기




Volumn 10, Issue , 2015, Pages 4937-4946

Nanoemulsions as novel oral carriers of stiripentol: Insights into the protective effect and absorption enhancement

Author keywords

Bioavailability; Intestinal permeability; Nanoemulsions; Stability; Stiripentol

Indexed keywords

MEDIUM CHAIN TRIACYLGLYCEROL; STIRIPENTOL; 1,3 DIOXOLANE DERIVATIVE; DRUG CARRIER; EMULSION; NANOPARTICLE;

EID: 84981722657     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/ijn.s87471     Document Type: Article
Times cited : (25)

References (35)
  • 3
    • 84925334416 scopus 로고    scopus 로고
    • Epilepsy treatment. Targeting LDH enzymes with a stiripentol analog to treat epilepsy
    • Sada N, Lee S, Katsu T, Otsuki T, Inoue T. Epilepsy treatment. Targeting LDH enzymes with a stiripentol analog to treat epilepsy. Science. 2015;347(6228):1362–1367.
    • (2015) Science , vol.347 , Issue.6228 , pp. 1362-1367
    • Sada, N.1    Lee, S.2    Katsu, T.3    Otsuki, T.4    Inoue, T.5
  • 4
    • 84903941333 scopus 로고    scopus 로고
    • Exploring the potential of self-assembled mixed micelles in enhancing the stability and oral bioavailability of an acid-labile drug
    • Zhang X, Wang H, Zhang T, Zhou X, Wu B. Exploring the potential of self-assembled mixed micelles in enhancing the stability and oral bioavailability of an acid-labile drug. Eur J Pharm Sci. 2014;62:301–308.
    • (2014) Eur J Pharm Sci , vol.62 , pp. 301-308
    • Zhang, X.1    Wang, H.2    Zhang, T.3    Zhou, X.4    Wu, B.5
  • 5
    • 39649099134 scopus 로고    scopus 로고
    • Physical characterization of lansoprazole/PVP solid dispersion prepared by fluid-bed coating technique
    • Zhang X, Sun N, Wu B, Lu Y, Guan T, Wu W. Physical characterization of lansoprazole/PVP solid dispersion prepared by fluid-bed coating technique. Powder Technol. 2008;182(3):480–485.
    • (2008) Powder Technol , vol.182 , Issue.3 , pp. 480-485
    • Zhang, X.1    Sun, N.2    Wu, B.3    Lu, Y.4    Guan, T.5    Wu, W.6
  • 6
    • 84897954465 scopus 로고    scopus 로고
    • Preparation of osthole-polymer solid dispersions by hot-melt extrusion for dissolution and bioavailability enhancement
    • Yun F, Kang A, Shan J, et al. Preparation of osthole-polymer solid dispersions by hot-melt extrusion for dissolution and bioavailability enhancement. Int J Pharm. 2014;465(1–2):436–443.
    • (2014) Int J Pharm , vol.465 , Issue.1-2 , pp. 436-443
    • Yun, F.1    Kang, A.2    Shan, J.3
  • 7
    • 59149106998 scopus 로고    scopus 로고
    • Piroxicam/2-hydroxypropyl-beta-cyclodextrin inclusion complex prepared by a new fluid-bed coating technique
    • Zhang X, Wu D, Lai J, Lu Y, Yin Z, Wu W. Piroxicam/2-hydroxypropyl-beta-cyclodextrin inclusion complex prepared by a new fluid-bed coating technique. J Pharm Sci. 2009;98(2):665–675.
    • (2009) J Pharm Sci , vol.98 , Issue.2 , pp. 665-675
    • Zhang, X.1    Wu, D.2    Lai, J.3    Lu, Y.4    Yin, Z.5    Wu, W.6
  • 8
    • 84878368922 scopus 로고    scopus 로고
    • Physicochemical characterization and pharmacokinetics evaluation of beta-caryophyllene/beta-cyclodextrin inclusion complex
    • Liu H, Yang G, Tang Y, et al. Physicochemical characterization and pharmacokinetics evaluation of beta-caryophyllene/beta-cyclodextrin inclusion complex. Int J Pharm. 2013;450(1–2):304–310.
    • (2013) Int J Pharm , vol.450 , Issue.1-2 , pp. 304-310
    • Liu, H.1    Yang, G.2    Tang, Y.3
  • 9
    • 84881234825 scopus 로고    scopus 로고
    • Solidification of nanostructured lipid carriers (NLCs) onto pellets by fluid-bed coating: Preparation, in vitro characterization and bioavailability in dogs
    • Tian Z, Yi Y, Yuan H, et al. Solidification of nanostructured lipid carriers (NLCs) onto pellets by fluid-bed coating: Preparation, in vitro characterization and bioavailability in dogs. Powder Technol. 2013;247:120–127.
    • (2013) Powder Technol , vol.247 , pp. 120-127
    • Tian, Z.1    Yi, Y.2    Yuan, H.3
  • 10
    • 84862291314 scopus 로고    scopus 로고
    • Solid self-nanoemulsifying cyclosporine A pellets prepared by fluid-bed coating: Stability and bioavailability study
    • Lei Y, Qi J, Nie S, et al. Solid self-nanoemulsifying cyclosporine A pellets prepared by fluid-bed coating: stability and bioavailability study. J Biomed Nanotechnol. 2012;8(3):515–521.
    • (2012) J Biomed Nanotechnol , vol.8 , Issue.3 , pp. 515-521
    • Lei, Y.1    Qi, J.2    Nie, S.3
  • 11
    • 84861702785 scopus 로고    scopus 로고
    • Development and characterization of a novel drug nanocarrier for oral delivery, based on self-assembled beta-casein micelles
    • Bachar M, Mandelbaum A, Portnaya I, et al. Development and characterization of a novel drug nanocarrier for oral delivery, based on self-assembled beta-casein micelles. J Control Release. 2012;160(2):164–171.
    • (2012) J Control Release , vol.160 , Issue.2 , pp. 164-171
    • Bachar, M.1    Mandelbaum, A.2    Portnaya, I.3
  • 12
    • 84877267457 scopus 로고    scopus 로고
    • Improved transport and absorption through gastrointestinal tract by PEGylated solid lipid nanoparticles
    • Yuan H, Chen CY, Chai GH, Du YZ, Hu FQ. Improved transport and absorption through gastrointestinal tract by PEGylated solid lipid nanoparticles. Mol Pharm. 2013;10(5):1865–1873.
    • (2013) Mol Pharm , vol.10 , Issue.5 , pp. 1865-1873
    • Yuan, H.1    Chen, C.Y.2    Chai, G.H.3    Du, Y.Z.4    Hu, F.Q.5
  • 13
    • 84912113254 scopus 로고    scopus 로고
    • Effects of PEGylated lipid nanoparticles on the oral absorption of one BCS II drug: A mechanistic investigation
    • Zhang X, Chen G, Zhang T, Ma Z, Wu B. Effects of PEGylated lipid nanoparticles on the oral absorption of one BCS II drug: a mechanistic investigation. Int J Nanomedicine. 2014;9:5503–5514.
    • (2014) Int J Nanomedicine , vol.9 , pp. 5503-5514
    • Zhang, X.1    Chen, G.2    Zhang, T.3    Ma, Z.4    Wu, B.5
  • 14
    • 85047286768 scopus 로고    scopus 로고
    • Polymeric micelles, a promising drug delivery system to enhance bioavailability of poorly water-soluble drugs
    • Xu W, Ling P, Zhang T. Polymeric micelles, a promising drug delivery system to enhance bioavailability of poorly water-soluble drugs. J Drug Deliv. 2013;2013:1–15.
    • (2013) J Drug Deliv , vol.2013 , pp. 1-15
    • Xu, W.1    Ling, P.2    Zhang, T.3
  • 16
    • 84938372331 scopus 로고    scopus 로고
    • Biodegradable polymeric nanoparticles for oral delivery of epirubicin: In vitro, ex vivo, and in vivo investigations
    • Tariq M, Alam MA, Singh AT, Iqbal Z, Panda AK, Talegaonkar S. Biodegradable polymeric nanoparticles for oral delivery of epirubicin: in vitro, ex vivo, and in vivo investigations. Colloids Surf B Biointerfaces. 2015;128:448–456.
    • (2015) Colloids Surf B Biointerfaces , vol.128 , pp. 448-456
    • Tariq, M.1    Alam, M.A.2    Singh, A.T.3    Iqbal, Z.4    Panda, A.K.5    Talegaonkar, S.6
  • 17
    • 84862833264 scopus 로고    scopus 로고
    • Liposomes containing glycocholate as potential oral insulin delivery systems: Preparation, in vitro characterization, and improved protection against enzymatic degradation
    • Niu M, Lu Y, Hovgaard L, Wu W. Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation. Int J Nanomedicine. 2011;6:1155–1166.
    • (2011) Int J Nanomedicine , vol.6 , pp. 1155-1166
    • Niu, M.1    Lu, Y.2    Hovgaard, L.3    Wu, W.4
  • 18
    • 84891002990 scopus 로고    scopus 로고
    • Biotinylated liposomes as potential carriers for the oral delivery of insulin
    • Zhang X, Qi J, Lu Y, He W, Li X, Wu W. Biotinylated liposomes as potential carriers for the oral delivery of insulin. Nanomedicine. 2014;10(1):167–176.
    • (2014) Nanomedicine , vol.10 , Issue.1 , pp. 167-176
    • Zhang, X.1    Qi, J.2    Lu, Y.3    He, W.4    Li, X.5    Wu, W.6
  • 19
    • 4344578729 scopus 로고    scopus 로고
    • Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation
    • Porter CJ, Kaukonen AM, Boyd BJ, Edwards GA, Charman WN. Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation. Pharm Res. 2004;21(8):1405–1412.
    • (2004) Pharm Res , vol.21 , Issue.8 , pp. 1405-1412
    • Porter, C.J.1    Kaukonen, A.M.2    Boyd, B.J.3    Edwards, G.A.4    Charman, W.N.5
  • 20
    • 84907236277 scopus 로고    scopus 로고
    • Porter CJ. ‘Stealth’ lipid-based formulations: Poly(ethylene glycol)-mediated digestion inhibition improves oral bioavailability of a model poorly water soluble drug
    • Feeney OM, Williams HD, Pouton CW, Porter CJ. ‘Stealth’ lipid-based formulations: Poly(ethylene glycol)-mediated digestion inhibition improves oral bioavailability of a model poorly water soluble drug. J Control Release. 2014;192:219–227.
    • (2014) J Control Release , vol.192 , pp. 219-227
    • Feeney, O.M.1    Williams, H.D.2    Pouton, C.W.3
  • 21
    • 84911443901 scopus 로고    scopus 로고
    • Effects of pharmaceutical PEGylation on drug metabolism and its clinical concerns
    • Zhang X, Wang H, Ma Z, Wu B. Effects of pharmaceutical PEGylation on drug metabolism and its clinical concerns. Expert Opin Drug Metab Toxicol. 2014;10(12):1691–1702.
    • (2014) Expert Opin Drug Metab Toxicol , vol.10 , Issue.12 , pp. 1691-1702
    • Zhang, X.1    Wang, H.2    Ma, Z.3    Wu, B.4
  • 22
    • 84921328529 scopus 로고    scopus 로고
    • Nanostructured lipid carriers used for oral delivery of oridonin: An effect of ligand modification on absorption
    • Zhou X, Zhang X, Ye Y, et al. Nanostructured lipid carriers used for oral delivery of oridonin: an effect of ligand modification on absorption. Int J Pharm. 2015;479(2):391–398.
    • (2015) Int J Pharm , vol.479 , Issue.2 , pp. 391-398
    • Zhou, X.1    Zhang, X.2    Ye, Y.3
  • 23
    • 79959486527 scopus 로고    scopus 로고
    • Prediction of human intestinal absorption of the prodrug temocapril by in situ single-pass perfusion using rat intestine with modified hydrolase activity
    • Nozawa T, Imai T. Prediction of human intestinal absorption of the prodrug temocapril by in situ single-pass perfusion using rat intestine with modified hydrolase activity. Drug Metab Dispos. 2011;39(7):1263–1269.
    • (2011) Drug Metab Dispos , vol.39 , Issue.7 , pp. 1263-1269
    • Nozawa, T.1    Imai, T.2
  • 24
    • 84901272511 scopus 로고    scopus 로고
    • Enhancement of oral bioavailability of tripterine through lipid nanospheres: Preparation, characterization, and absorption evaluation
    • Zhang X, Zhang T, Zhou X, et al. Enhancement of oral bioavailability of tripterine through lipid nanospheres: preparation, characterization, and absorption evaluation. J Pharm Sci. 2014;103(6):1711–1719.
    • (2014) J Pharm Sci , vol.103 , Issue.6 , pp. 1711-1719
    • Zhang, X.1    Zhang, T.2    Zhou, X.3
  • 25
    • 84866161947 scopus 로고    scopus 로고
    • Size-dependent absorption mechanism of polymeric nanoparticles for oral delivery of protein drugs
    • He C, Yin L, Tang C, Yin C. Size-dependent absorption mechanism of polymeric nanoparticles for oral delivery of protein drugs. Biomaterials. 2012;33(33):8569–8578.
    • (2012) Biomaterials , vol.33 , Issue.33 , pp. 8569-8578
    • He, C.1    Yin, L.2    Tang, C.3    Yin, C.4
  • 26
    • 59349092521 scopus 로고    scopus 로고
    • Localization and quantification of biodegradable particles in an intestinal cell model: The influence of particle size
    • Gaumet M, Gurny R, Delie F. Localization and quantification of biodegradable particles in an intestinal cell model: The influence of particle size. Eur J Pharm Sci. 2009;36(4–5):465–473.
    • (2009) Eur J Pharm Sci , vol.36 , Issue.45 , pp. 465-473
    • Gaumet, M.1    Gurny, R.2    Delie, F.3
  • 27
    • 84904660041 scopus 로고    scopus 로고
    • Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-alpha-tocopheryl polyethylene glycol 1000 succinate nanoemulsions
    • Sun D, Wei X, Xue X, et al. Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-alpha-tocopheryl polyethylene glycol 1000 succinate nanoemulsions. Int J Nanomedicine. 2014;9:3413–3423.
    • (2014) Int J Nanomedicine , vol.9 , pp. 3413-3423
    • Sun, D.1    Wei, X.2    Xue, X.3
  • 28
    • 84885070935 scopus 로고    scopus 로고
    • Nanoemulsion improves the oral bioavailability of baicalin in rats: In vitro and in vivo evaluation
    • Zhao L, Wei Y, Fu J, Huang Y, He B, Zhou Y. Nanoemulsion improves the oral bioavailability of baicalin in rats: in vitro and in vivo evaluation. Int J Nanomedicine. 2013;8:3769–3779.
    • (2013) Int J Nanomedicine , vol.8 , pp. 3769-3779
    • Zhao, L.1    Wei, Y.2    Fu, J.3    Huang, Y.4    He, B.5    Zhou, Y.6
  • 29
    • 33847394968 scopus 로고    scopus 로고
    • Lipids and lipid-based formulations: Optimizing the oral delivery of lipophilic drugs
    • Porter CJ, Trevaskis NL, Charman WN. Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. Nat Rev Drug Discov. 2007;6(3):231–248.
    • (2007) Nat Rev Drug Discov , vol.6 , Issue.3 , pp. 231-248
    • Porter, C.J.1    Trevaskis, N.L.2    Charman, W.N.3
  • 30
    • 0031958251 scopus 로고    scopus 로고
    • Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(Ethylene glycol) and D-peptides
    • He YL, Murby S, Warhurst G, et al. Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-peptides. J Pharm Sci. 1998;87(5):626–633.
    • (1998) J Pharm Sci , vol.87 , Issue.5 , pp. 626-633
    • He, Y.L.1    Murby, S.2    Warhurst, G.3
  • 31
    • 84865731585 scopus 로고    scopus 로고
    • Nanoemulsion delivery systems: Influence of carrier oil on beta-carotene bioaccessibility
    • Qian C, Decker EA, Xiao H, McClements DJ. Nanoemulsion delivery systems: influence of carrier oil on beta-carotene bioaccessibility. Food Chem. 2012;135(3):1440–1447.
    • (2012) Food Chem , vol.135 , Issue.3 , pp. 1440-1447
    • Qian, C.1    Decker, E.A.2    Xiao, H.3    McClements, D.J.4
  • 32
    • 39149108776 scopus 로고    scopus 로고
    • Lipid-based delivery systems and intestinal lymphatic drug transport: A mechanistic update
    • Trevaskis NL, Charman WN, Porter CJ. Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update. Adv Drug Del Rev. 2008;60(6):702–716.
    • (2008) Adv Drug Del Rev , vol.60 , Issue.6 , pp. 702-716
    • Trevaskis, N.L.1    Charman, W.N.2    Porter, C.J.3
  • 33
    • 84902206847 scopus 로고    scopus 로고
    • Optimizing surfactant content to improve oral bioavailability of ibuprofen in microemulsions: Just enough or more than enough?
    • You X, Xing Q, Tuo J, Song W, Zeng Y, Hu H. Optimizing surfactant content to improve oral bioavailability of ibuprofen in microemulsions: just enough or more than enough? Int J Pharm. 2014;471(1–2):276–284.
    • (2014) Int J Pharm , vol.471 , Issue.1-2 , pp. 276-284
    • You, X.1    Xing, Q.2    Tuo, J.3    Song, W.4    Zeng, Y.5    Hu, H.6
  • 34
    • 0031885344 scopus 로고    scopus 로고
    • Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells
    • Lindmark T, Kimura Y, Artursson P. Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells. J Pharmacol Exp Ther. 1998;284(1):362–369.
    • (1998) J Pharmacol Exp Ther , vol.284 , Issue.1 , pp. 362-369
    • Lindmark, T.1    Kimura, Y.2    Artursson, P.3
  • 35
    • 34848857371 scopus 로고    scopus 로고
    • Predicting human intestinal permeability using single-pass intestinal perfusion in rat
    • Zakeri-Milani P, Valizadeh H, Tajerzadeh H, et al. Predicting human intestinal permeability using single-pass intestinal perfusion in rat. J Pharm Pharm Sci. 2007;10(3):368–379.
    • (2007) J Pharm Pharm Sci , vol.10 , Issue.3 , pp. 368-379
    • Zakeri-Milani, P.1    Valizadeh, H.2    Tajerzadeh, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.