Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition

Neuropsychopharmacology

Volumn 39, Issue 11, 2014, Pages 2646-2653

  Koo, Ja Wook ^a   Lobo, Mary Kay ^b   Chaudhury, Dipesh ^a   Labonté, Benoit ^a   Friedman, Allyson ^a   Heller, Elizabeth ^a   Peña, Catherine Jensen ^a   Han, Ming Hu ^a   Nestler, Eric J ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; MORPHINE; NARCOTIC AGENT;

ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENETICS; INHIBITORY POSTSYNAPTIC POTENTIAL; KNOCKOUT MOUSE; METABOLISM; NUCLEUS ACCUMBENS; PHYSIOLOGY; REWARD; TISSUE CULTURE TECHNIQUE;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; GABA-A RECEPTOR ANTAGONISTS; GABAERGIC NEURONS; GAMMA-AMINOBUTYRIC ACID; INHIBITORY POSTSYNAPTIC POTENTIALS; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHINE; NARCOTICS; NUCLEUS ACCUMBENS; RECEPTOR, TRKB; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; RECEPTORS, GABA-A; REWARD; TISSUE CULTURE TECHNIQUES;

EID: 84939893302     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.118     Document Type: Article

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