Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors

Oncotarget

Volumn 7, Issue 6, 2016, Pages 6891-6901

  Nunes Xavier, Caroline E ^a   Karlsen, Karine Flem ^a   Tekle, Christina ^a   Pedersen, Cathrine ^a   Øyjord, Tove ^a   Hongisto, Vesa ^b   Nesland, Jahn M ^a   Tan, Ming ^c   Sahlberg, Kristine Kleivi ^d,e   Fodstad, Øystein ^a,e  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b Misvik Biology Corporation   (Finland)

^c UNIVERSITY OF SOUTH ALABAMA   (United States)

^d Vestre Viken ^*  (Norway)

^e UNIVERSITY OF OSLO   (Norway)

Author keywords

API 2; Breast cancer cells; CD276 B7 H3; Everolimus; Glycolysis

Indexed keywords

EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRICIRIBINE; B7 ANTIGEN; CD276 PROTEIN, HUMAN; MTOR PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B7 H3 GENE; BREAST CANCER CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG SENSITIVITY; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; GLYCOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; ONCOGENE; PHASE 1 CLINICAL TRIAL (TOPIC); PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST CANCER; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BIOSYNTHESIS; GENETICS; METABOLISM; NUDE MOUSE; PHOSPHORYLATION; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR CELL LINE;

ANIMALS; B7 ANTIGENS; CELL LINE, TUMOR; FEMALE; GLYCOLYSIS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 84980727921     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6902     Document Type: Article

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