B7-H3 and its relevance in cancer; Immunological and non-immunological perspectives

Frontiers in Bioscience - Elite

Volumn 3 E, Issue 3, 2011, Pages 989-993

  Nygren, Marit Kveine ^a   Tekle, Christina ^a   Ingebrigtsen, Vibeke Anett ^a   Fodstad, Oystein ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

B7 H3; Chemosensitivity; Metastasis; Review; Signaling Pathways

Indexed keywords

B LYMPHOCYTE RECEPTOR; B7 H3 PROTEIN; CD3 ANTIBODY; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GLYCOPROTEIN; MEMBRANE PROTEIN; STAT3 PROTEIN; T LYMPHOCYTE RECEPTOR; TUMOR ANTIGEN; UNCLASSIFIED DRUG; CD276 PROTEIN, HUMAN; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN;

ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER IMMUNOLOGY; CANCER INHIBITION; CANCER PROGNOSIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CHEMOSENSITIVITY; COLORECTAL CANCER; CYTOKINE PRODUCTION; GENE SILENCING; GLIOMA; HUMAN; LUNG NON SMALL CELL CANCER; LYMPHOCYTE PROLIFERATION; MELANOMA; METASTASIS; METASTASIS POTENTIAL; NEOPLASM; NEUROBLASTOMA; NONHUMAN; OSTEOSARCOMA; PHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; STOMACH CARCINOMA; T LYMPHOCYTE ACTIVATION; TUMOR IMMUNITY; WILD TYPE; ANIMAL; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD; HUMANS; LYMPHOCYTE ACTIVATION; NEOPLASMS; RECEPTORS, IMMUNOLOGIC; T-LYMPHOCYTES;

EID: 80053592476     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: 10.2741/e304     Document Type: Article

References (36)

1. B. Seliger, F. M. Marincola, S. Ferrone and H. Abken: The complex role of B7 molecules in tumor immunology. Trends Mol Med, 14, 550-9(2008)
2. B. M. Carreno and M. Collins: The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu Rev Immunol, 20, 29-53(2002) (Pubitemid 34293419)
3. M. Collins, V. Ling and B. M. Carreno: The B7 family of immune-regulatory ligands. Genome Biol, 6, 223(2005)
4. A. Hutloff, A. M. Dittrich, K. C. Beier, B. Eljaschewitsch, R. Kraft, I. Anagnostopoulos and R. A. Kroczek: ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature, 397, 263-6(1999)
5. T. W. Mak, A. Shahinian, S. K. Yoshinaga, A. Wakeham, L. M. Boucher, M. Pintilie, G. Duncan, B. U. Gajewska, M. Gronski, U. Eriksson, B. Odermatt, A. Ho, D. Bouchard, J. S. Whorisky, M. Jordana, P. S. Ohashi, T. Pawson, F. Bladt and A. Tafuri: Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses. Nat Immunol, 4, 765-72(2003) (Pubitemid 36986760)
6. S. Wang, G. Zhu, A. I. Chapoval, H. Dong, K. Tamada, J. Ni and L. Chen: Costimulation of T cells by B7-H2, a B7- like molecule that binds ICOS. Blood, 96, 2808-13(2000)
7. H. Dong, G. Zhu, K. Tamada and L. Chen: B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med, 5, 1365-9(1999)
8. A. Augello., R. Tasso, S. M. Negrini, A. Amateis, F. Indiveri, R. Cancedda and G. Pennesi: Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur J Immunol, 35, 1482-90(2005) (Pubitemid 40691430)
9. J. Hori, M. Wang, M. Miyashita, K. Tanemoto, H. Takahashi, T. Takemori, K. Okumura, H. Yagita and M. Azuma: B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts. J Immunol, 177, 5928-35(2006) (Pubitemid 44628806)
10. M. M. Mazanet and C. C. Hughes: B7-H1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis. J Immunol, 169, 3581-8(2002)
11. A. Saudemont, N. Jouy, D. Hetuin and B. Quesnel: NK cells that are activated by CXCL10 can kill dormant tumor cells that resist CTL-mediated lysis and can express B7-H1 that stimulates T cells. Blood, 105, 2428-35(2005) (Pubitemid 40387042)
12. L. Carter, L. A. Fouser, J. Jussif, L. Fitz, B. Deng, C. R. Wood, M. Collins, T. Honjo, G. J. Freeman and B. M. Carreno: PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2. Eur J Immunol, 32, 634-43(2002) (Pubitemid 34257540)
13. V. Ling, P. W. Wu, V. Spaulding, J. Kieleczawa, D. Luxenberg, B. M. Carreno and M. Collins: Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss. Genomics, 82, 365-77(2003) (Pubitemid 36952307)
14. A. I. Chapoval, J. Ni, J. S. Lau, R. A. Wilcox, D. B. Flies, D. Liu, H. Dong, G. L. Sica, G. Zhu, K. Tamada and L. Chen: B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Nat Immunol, 2, 269-74(2001) (Pubitemid 33706005)
15. G. L. Sica, I. H. Choi, G. Zhu, K. Tamada, S. D. Wang, H. Tamura, A. I. Chapoval, D. B. Flies, J. Bajorath and L. Chen: B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. Immunity, 18, 849-61(2003) (Pubitemid 36776432)
16. A. Fukushima, T. Sumi, K. Fukuda, N. Kumagai, T. Nishida, T. Yamazaki, H. Akiba, K. Okumura, H. Yagita and H. Ueno: B7-H3 regulates the development of experimental allergic conjunctivitis in mice. Immunol Lett, 113, 52-7(2007) (Pubitemid 47464618)
17. D. V. Prasad, T. Nguyen, Z. Li, Y. Yang, J. Duong, Y. Wang and C. Dong: Murine B7-H3 is a negative regulator of T cells. J Immunol, 173, 2500-6(2004) (Pubitemid 39063108)
18. W. K. Suh, B. U. Gajewska, H. Okada, M. A. Gronski, E. M. Bertram, W. Dawicki, G. S. Duncan, J. Bukczynski, S. Plyte, A. Elia, A. Wakeham, A. Itie, S. Chung, J. Da Costa, S. Arya, T. Horan, P. Campbell, K. Gaida, P. S. Ohashi, T. H. Watts, S. K. Yoshinaga, M. R. Bray, M. Jordana and T. W. Mak: The B7 family member B7-H3 preferentially downregulates T helper type 1-mediated immune responses. Nat Immunol, 4, 899-906(2003) (Pubitemid 37098661)
19. C. M. Lupu, C. Eisenbach, M. A. Kuefner, J. Schmidt, A. D. Lupu, W. Stremmel and J. Encke: An orthotopic colon cancer model for studying the B7-H3 antitumor effect in vivo. J Gastrointest Surg, 10, 635-45(2006) (Pubitemid 43711146)
20. L. Luo, A. I. Chapoval, D. B. Flies, G. Zhu, F. Hirano, S. Wang, J. S. Lau, H. Dong, K. Tamada, A. S. Flies, Y. Liu and L. Chen: B7-H3 enhances tumor immunity in vivo by costimulating rapid clonal expansion of antigen-specific CD8+ cytolytic T cells. J Immunol, 173, 5445-50(2004) (Pubitemid 39392128)
21. L. Luo, H. Qiao, F. Meng, X. Dong, B. Zhou, H. Jiang, J. R. Kanwar, G. W. Krissansen and X. Sun: Arsenic trioxide synergizes with B7H3-mediated immunotherapy to eradicate hepatocellular carcinomas. Int J Cancer, 118, 1823-30(2006) (Pubitemid 43376449)
22. C. P. Wu, J. T. Jiang, M. Tan, Y. B. Zhu, M. Ji, K. F. Xu, J. M. Zhao, G. B. Zhang and X. G. Zhang: Relationship between costimulatory molecule B7-H3 expression and gastric carcinoma histology and prognosis. World J Gastroenterol, 12, 457-9(2006) (Pubitemid 43329266)
23. M. Loos, D. M. Hedderich, M. Ottenhausen, N. A. Giese, M. Laschinger, I. Esposito, J. Kleeff and H. Friess: Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer. BMC Cancer, 9, 463(2009)
24. X. Zang, P. S. Sullivan, R. A. Soslow, R. Waitz, V. E. Reuter, A. Wilton, H. T. Thaler, M. Arul, S. F. Slovin, J. Wei, D. R. Spriggs, J. Dupont and J. P. Allison: Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas. Mod Pathol (2010)
25. P. L. Crispen, Y. Sheinin, T. J. Roth, C. M. Lohse, S. M. Kuntz, X. Frigola, R. H. Thompson, S. A. Boorjian, H. Dong, B. C. Leibovich, M. L. Blute and E. D. Kwon: Tumor cell and tumor vasculature expression of B7-H3 predict survival in clear cell renal cell carcinoma. Clin Cancer Res, 14, 5150-7(2008)
26. Y. Sun, Y. Wang, J. Zhao, M. Gu, R. Giscombe, A. K. Lefvert and X. Wang: B7-H3 and B7-H4 expression in non-small-cell lung cancer. Lung Cancer, 53, 143-51(2006) (Pubitemid 43994236)
27. I. Yamato, M. Sho, T. Nomi, T. Akahori, K. Shimada, K. Hotta, H. Kanehiro, N. Konishi, H. Yagita and Y. Nakajima: Clinical importance of B7-H3 expression in human pancreatic cancer. Br J Cancer, 101, 1709-16(2009)
28. G. Zhang, Y. Xu, X. Lu, H. Huang, Y. Zhou, B. Lu and X. Zhang: Diagnosis value of serum B7-H3 expression in nonsmall cell lung cancer. Lung Cancer, 66, 245-9(2009)
29. H. Lee, J. H. Kim, S. Y. Yang, J. Kong, M. Oh, D. H. Jeong, J. I. Chung, K. B. Bae, J. Y. Shin, K. H. Hong and I. Choi: Peripheral blood gene expression of B7 and CD28 family members associated with tumor progression and microscopic lymphovascular invasion in colon cancer patients. J Cancer Res Clin Oncol (2010)
30. R. Brackenbury: Molecular mechanisms of cell adhesion in normal and transformed cells. Cancer Metastasis Rev, 4, 41-58(1985)
31. O. Merimsky, Y. Shoenfeld, S. Chaitchik, G. Yecheskel and P. Fishman: Antigens and antibodies in malignant melanoma. Tumour Biol, 15, 188-202(1994) (Pubitemid 24321990)
32. A. J. Miller and M. C. Mihm, Jr.: Melanoma. N Engl J Med, 355, 51-65(2006)
33. M. Streit and M. Detmar: Angiogenesis, lymphangiogenesis, and melanoma metastasis. Oncogene, 22, 3172-9(2003) (Pubitemid 36713769)
34. S. Tveito, G. M. Maelandsmo, H. K. Hoifodt, H. Rasmussen and O. Fodstad: Specific isolation of disseminated cancer cells: a new method permitting sensitive detection of target molecules of diagnostic and therapeutic value. Clin Exp Metastasis, 24, 317-27(2007) (Pubitemid 47124933)
35. Y. W. Chen, C. Tekle and O. Fodstad: The immunoregulatory protein human B7H3 is a tumorassociated antigen that regulates tumor cell migration and invasion. Curr Cancer Drug Targets, 8, 404-13(2008)
36. E. Devarajan and S. Huang: STAT3 as a central regulator of tumor metastases. Curr Mol Med, 9, 626-33(2009)