Silencing of hypoxia inducible factor-1α gene attenuated angiotensin Ⅱ-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice

Atherosclerosis

Volumn 252, Issue , 2016, Pages 40-49

  Yang, Le ^a   Shen, Lin ^b   Li, Gang ^a   Yuan, Hai ^a   Jin, Xing ^a   Wu, Xuejun ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Abdominal aortic aneurysm; HIF 1 ; Inflammation; MMP; Neovascularity

Indexed keywords

ANGIOGENIC FACTOR; ANGIOTENSIN II; APOLIPOPROTEIN E; GELATINASE A; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LENTIVIRUS VECTOR; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; SHORT HAIRPIN RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TUMOR NECROSIS FACTOR ALPHA; HIF1A PROTEIN, MOUSE; SMALL INTERFERING RNA;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; GENE SILENCING; GENETIC TRANSFECTION; HYPERLIPOPROTEINEMIA TYPE 3; IN VIVO STUDY; MACROPHAGE; MICROVASCULATURE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; UPREGULATION; VIRAL GENE THERAPY; ABDOMINAL AORTIC ANEURYSM; ANIMAL; APOLIPOPROTEIN E KNOCKOUT MOUSE; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; GENETICS; HYPOXIA; INFLAMMATION; LENTIVIRINAE; MALE; METABOLISM; MICROCIRCULATION; SIGNAL TRANSDUCTION; TIME FACTOR;

ANGIOTENSIN II; ANIMALS; AORTIC ANEURYSM, ABDOMINAL; DISEASE MODELS, ANIMAL; GENE SILENCING; HYPOXIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION; LENTIVIRUS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT, APOE; MICROCIRCULATION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS; UP-REGULATION;

EID: 84980331985     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2016.07.010     Document Type: Article

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