Angiotensin II Induces an Increase in Matrix Metalloproteinase 2 Expression in Aortic Smooth Muscle Cells of Ascending Thoracic Aortic Aneurysms Through JNK, ERK1/2, and p38 MAPK Activation

Journal of Cardiovascular Pharmacology

Volumn 66, Issue 3, 2015, Pages 285-293

  Wang, Chunmao ^a   Chang, Qian ^a   Sun, Xiaogang ^a   Qian, Xiangyang ^a   Liu, Penghong ^a   Pei, Huawei ^a   Guo, Xiaobo ^a   Liu, Wenzhi ^a  

^a FUWAI HOSPITAL   (China)

Author keywords

angiotensin II; aortic aneurysm; ERK1 2; JNK; matrix metalloproteinase 2; p38 MAPK; thoracic

Indexed keywords

ANGIOTENSIN II; ANGIOTENSINOGEN; GELATINASE A; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; MAPK1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

ARTICLE; ASCENDING AORTA; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; ISCHEMIC HEART DISEASE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; SMOOTH MUSCLE FIBER; THORACIC AORTA ANEURYSM; UPREGULATION; WESTERN BLOTTING; ADULT; AGED; AORTA; BLOOD; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; MIDDLE AGED; PHOSPHORYLATION; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CELL;

ADULT; AGED; ANGIOTENSIN II; AORTA; AORTIC ANEURYSM, THORACIC; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, SMOOTH MUSCLE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PRIMARY CELL CULTURE; UP-REGULATION;

EID: 84942032547     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0000000000000276     Document Type: Article

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