Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype: Implications for GI Infection, IBD, POI, Neurological, Motility, and GI Disorders

Inflammatory Bowel Diseases

Volumn 22, Issue 8, 2016, Pages 1812-1834

  Liñán Rico, Andromeda ^a   Turco, Fabio ^b   Ochoa Cortes, Fernando ^a   Harzman, Alan ^a   Needleman, Bradley J ^a   Arsenescu, Razvan ^a   Abdel Rasoul, Mahmoud ^a   Fadda, Paolo ^c   Grants, Iveta ^a   Whitaker, Emmett ^d   Cuomo, Rosario ^b   Christofi, Fievos L ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c OHIO STATE UNIVERSITY   (United States)

^d NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

adenosine; ATP; bacterial lipopolysaccharide; Ca 2+ signaling; human enteric glial cells; mechanosensitivity; purinergic signaling

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; CALCIUM ION; CATION CHANNEL; CXCL2 CHEMOKINE; FLUO 4; FLUORESCENT DYE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 22; INTERLEUKIN 33; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN S100B; PURINERGIC P2Y2 RECEPTOR; PURINERGIC P2Y6 RECEPTOR; PURINERGIC RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VESICULAR TRANSPORT PROTEIN; CALCIUM; CALCIUM CHANNEL; CARRIER PROTEIN; CASP3 PROTEIN, HUMAN; CASPASE 3; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEME OXYGENASE 1; HMOX1 PROTEIN, HUMAN; IGFBP5-INTERACTING PROTEIN, HUMAN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE A; MANGANESE SUPEROXIDE DISMUTASE; NOS2 PROTEIN, HUMAN; S100B PROTEIN, HUMAN; SIGNAL PEPTIDE; SUPEROXIDE DISMUTASE; TPH2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRYPTOPHAN HYDROXYLASE;

ARTICLE; CALCIUM SIGNALING; CLINICAL ARTICLE; COLON RESECTION; CONTROLLED STUDY; ENTERIC GLIAL CELL; FLOW RATE; GASTROINTESTINAL DISEASE; GASTROINTESTINAL INFECTION; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL MOTILITY DISORDER; GENE EXPRESSION; GLIA CELL; GLIAL CELL CULTURE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INFLAMMATORY BOWEL DISEASE; MECHANOTRANSDUCTION; NEUROLOGIC DISEASE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SECRETION; SIGNAL TRANSDUCTION; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; GLIA; INTESTINE INNERVATION; JEJUNUM; METABOLISM; SIGMOID; UPREGULATION;

ADENOSINE TRIPHOSPHATE; CALCIUM; CALCIUM CHANNELS; CARRIER PROTEINS; CASPASE 3; CELLS, CULTURED; COLON, SIGMOID; CYTOKINES; ENTERIC NERVOUS SYSTEM; GASTROINTESTINAL DISEASES; GASTROINTESTINAL MOTILITY; GENE EXPRESSION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEME OXYGENASE-1; HUMANS; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERFERON-GAMMA; JEJUNUM; LIPOPOLYSACCHARIDES; MECHANOTRANSDUCTION, CELLULAR; NEUROGLIA; NITRIC OXIDE SYNTHASE TYPE II; PHENOTYPE; RECEPTORS, PURINERGIC; S100 CALCIUM BINDING PROTEIN BETA SUBUNIT; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS; TRYPTOPHAN HYDROXYLASE; UP-REGULATION; VESICULAR TRANSPORT PROTEINS;

EID: 84979884714     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0000000000000854     Document Type: Article

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