A Mutation in the 16S rRNA decoding region attenuates the virulence of Mycobacterium tuberculosis

Infection and Immunity

Volumn 84, Issue 8, 2016, Pages 2264-2273

  Watanabe, Shinya ^a,g   Matsumura, Kazunori ^a   Iwai, Hiroki ^a   Funatogawa, Keiji ^b   Haishima, Yuji ^c   Fukui, Chie ^c   Okumura, Kayo ^d   Kato Miyazawa, Masako ^a   Hashimoto, Masahito ^e   Teramoto, Kanae ^f   Kirikae, Fumiko ^a   Miyoshi Akiyama, Tohru ^a   Kirikaea, Teruo ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b Tochigi Prefectural Institute of Public Health and Environmental Science   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

^e KAGOSHIMA UNIVERSITY   (Japan)

^f JEOL LTD   (Japan)

^g JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; EARLY SECRETORY ANTIGENIC TARGET 6; ETHAMBUTOL; HYGROMYCIN B; ISONIAZID; KANAMYCIN; LEVOFLOXACIN; MYCOLIC ACID; RIFABUTIN; RIFAMPICIN; RNA 16S; STREPTOMYCIN; VIRULENCE FACTOR; TUBERCULOSTATIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BINDING SITE; ENZYME SYNTHESIS; GENOTYPE; IN VITRO STUDY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OPERON; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIBOSOME; TRANSLATION INITIATION; ANIMAL; CHEMISTRY; CONFORMATION; DRUG EFFECTS; GENETIC COMPLEMENTATION; GENETICS; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIAL VIABILITY; MICROBIOLOGY; MUTATION; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PROCEDURES; PROTEOMICS; TUBERCULOSIS; VIRULENCE;

ANIMALS; ANTITUBERCULAR AGENTS; BASE SEQUENCE; DRUG RESISTANCE, BACTERIAL; GENETIC COMPLEMENTATION TEST; MICE; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MUTATION; MYCOBACTERIUM TUBERCULOSIS; NUCLEIC ACID CONFORMATION; PROTEOMICS; RNA, RIBOSOMAL, 16S; TUBERCULOSIS; VIRULENCE; VIRULENCE FACTORS;

EID: 84979759210     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00417-16     Document Type: Article

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