Synthesis and biofilm formation reduction of pyrazole-4-carboxamide derivatives in some Staphylococcus aureus strains

European Journal of Medicinal Chemistry

Volumn 123, Issue , 2016, Pages 58-68

  Cascioferro, Stella ^a,b   Maggio, Benedetta ^a   Raffa, Demetrio ^a   Raimondi, Maria Valeria ^a   Cusimano, Maria Grazia ^a   Schillaci, Domenico ^a   Manachini, Barbara ^a   Plescia, Fabiana ^a   Daidone, Giuseppe ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b Istituto EuroMediterraneo di Scienza e Tecnologia   (Italy)

Author keywords

Anti virulence; Inhibition of biofilm formation; N phenyl 1H pyrazole 4 carboxamides; S. aureus; Wax moth larva model

Indexed keywords

1 (2,5 3 DIFLUOROPHENYL) 5 METHYL N PHENYL 1H PYRAZOLE 4 CARBOXAMIDE; 1 (2,5 DICHLOROPHENYL) 5 METHYL N PHENYL 1H PYRAZOLE 4 CARBOXAMIDE; 1 (3 CHLOROPHENYL) 5 METHYL N PHENYL 1H PYRAZOLE 4 CARBOXAMIDE; 1 (4 CHLOROPHENYL) 5 METHYL N PHENYL 1H PYRAZOLE 4 CARBOXAMIDE; 2 [[2 (2,5 DICHLOROPHENYL)HYDRAZINYL]METHYLENE] 3 OXO N PHENYLBUTANAMIDE; 3 METHYL N,1 DIPHENYL 1H PYRAZOLE 5 CARBOXAMIDE; 5 METHYL 1 (3 NITROPHENYL) N PHENYL 1H PYRAZOLE 4 CARBOXAMIDE; 5 METHYL N PHENYL 1 [4 (TRIFLUOROMETHYL)PHENY]) 1H PYRAZOLE 4 CARBOXAMIDE; 5 METHYL N,1 DIPHENYL 1H PYRAZOLE 3 CARBOXAMIDE; ANTIBIOTIC AGENT; PYRAZOLE 4 CARBOXAMIDE DERIVATIVE; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG; 2-((2-(2,5-DICHLOROPHENYL)HYDRAZINYL)METHYLENE)-3-OXO-N-PHENYLBUTANAMIDE; ANTIINFECTIVE AGENT; HYDRAZINE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BIOFILM; DRUG SYNTHESIS; GALLERIA MELLONELLA; IC50; LARVA; NONHUMAN; STAPHYLOCOCCUS AUREUS; SURVIVAL; ANIMAL; DRUG EFFECTS; MICROBIOLOGY; MOTH; PHYSIOLOGY; STAPHYLOCOCCAL INFECTIONS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; VIRULENCE;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; HYDRAZINES; LARVA; MOTHS; PYRAZOLES; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRULENCE;

EID: 84979633614     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2016.07.030     Document Type: Article

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