SCOPUS 정보 검색 플랫폼

Volumn 54, Issue , 2012, Pages 709-720

Synthesis, benzodiazepine receptor binding and molecular modelling of isochromeno[4,3-c]pyrazol-5(1H)-one derivatives

(10) Maggio, B a Raffa, D a Raimondi, M V a Plescia, F a Trincavelli, M L b Martini, C b Meneghetti, F c Basile, L e Guccione, S d,e Daidone, G a

a UNIVERSITY OF PALERMO (Italy)

b UNIVERSITY OF PISA (Italy)

c UNIVERSITY OF MILAN (Italy)

d UNIVERSITY OF CATANIA (Italy)

e SCUOLA SUPERIORE DI CATANIA (Italy)

Author keywords

Benzodiazepine receptor; Dihydrospiro isoindole 1,3' pyrazol 3(2H) ones; Isochromeno 4,3 c pirazoles

Indexed keywords

1 PHENYLISOCHROMENO [4,3 C] PYRAZOLE 5(1H) ONE; 1(3 CHLOROPHENYL) 3 METHYLISOCHROMENO [4,3 C] PYRAZOLE 5(1H) ONE; 1(3 METHYLPHENYL) 3 METHYLISOCHROMENO [4,3 C] PYRAZOLE 5(1H) ONE; 1(4 METHYLPHENYL) 3 METHYLISOCHROMENO [4,3 C] PYRAZOLE 5(1H) ONE; 3,7 DIMETHYL 1 PHENYLISOCHROMENO [4,3 C] PYRAZOLE 5(1H) ONE; 7 CHLORO 3 METHYL 1 PHENYLISOCHROMENO [4,3 C] PYRAZOLE 5(1H) ONE; 8 CHLORO 3 METHYL 1 PHENYLISOCHROMENO [4,3 C] PYRAZOLE 5(1H) ONE; BENZODIAZEPINE RECEPTOR; CHROMENO [4,3 C] PYRAZOL 5(1H) ONE DERIVATIVE; DIAZEPAM; FLUNITRAZEPAM; ISOCHROMENO [4,3 C] PYRAZOL 5(1H) ONE DERIVATIVE; PYRAZOLE DERIVATIVE; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; BRAIN MEMBRANE; COMPARATIVE STUDY; CONTROLLED STUDY; COW; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERISM; MOLECULAR MODEL; NONHUMAN; RECEPTOR AFFINITY; RECEPTOR BINDING;

ANIMALS; BENZOPYRANS; CATTLE; CHEMISTRY TECHNIQUES, SYNTHETIC; HUMANS; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; PYRAZOLES; RECEPTORS, GABA-A;

EID: 84864417084 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.06.028 Document Type: Article

Times cited : (22)

References (28)

1
- 0036676629
- E. Sigel Curr. Top. Med. Chem. 2 2002 833 839
- (2002) Curr. Top. Med. Chem. , vol.2 , pp. 833-839
- Sigel, E.¹

2
- 16444387677
- M.H. Akabas Int. Rev. Neurobiol. 62 2004 1 43
- (2004) Int. Rev. Neurobiol. , vol.62 , pp. 1-43
- Akabas, M.H.¹

3
- 0025967183
- H.O. Villar, M.F. Davies, G.H. Loew, and P.A. Marguire Life Sci. 48 1991 593 602
- (1991) Life Sci. , vol.48 , pp. 593-602
- Villar, H.O.¹ Davies, M.F.² Loew, G.H.³ Marguire, P.A.⁴

4
- 33748654451
- G. Daidone, B. Maggio, D. Raffa, S. Plescia, F. Benetollo, and G. Bombieri J. Chem. Soc., Perkin Trans. 1 1998 2891 2897
- (1998) J. Chem. Soc., Perkin Trans. 1 , pp. 2891-2897
- Daidone, G.¹ Maggio, B.² Raffa, D.³ Plescia, S.⁴ Benetollo, F.⁵ Bombieri, G.⁶

5
- 15244351637
- G. Daidone, S. Plescia, and J. Fabra J. Heterocycl. Chem. 17 1980 1409 1411
- (1980) J. Heterocycl. Chem. , vol.17 , pp. 1409-1411
- Daidone, G.¹ Plescia, S.² Fabra, J.³

6
- 0021046255
- S. Plescia, G. Daidone, and V. Sprio Boll. Chim. Farm. 122 1983 190 195
- (1983) Boll. Chim. Farm. , vol.122 , pp. 190-195
- Plescia, S.¹ Daidone, G.² Sprio, V.³

7
- 33747004017
- C.K. Johnson ORTEP II Report ORNL-5138 1976 Oak Ridge National Laboratory TN
- (1976) ORTEP II Report ORNL-5138 1976 Oak Ridge National Laboratory TN
- Johnson, C.K.¹

8
- 1842692143
- D. Cremer, and J.A. Pople J. Am. Chem. Soc. 97 1975 1354 1358
- (1975) J. Am. Chem. Soc. , vol.97 , pp. 1354-1358
- Cremer, D.¹ Pople, J.A.²

9
- 84864397789
- V. Colotta, L. Cecchi, G. Filacchioni, F. Melani, G. Palazzino, C. Martini, G. Giannaccini, and A. Lucacchini J. Med. Chem. 31 1988 3 5
- (1988) J. Med. Chem. , vol.31 , pp. 3-5
- Colotta, V.¹ Cecchi, L.² Filacchioni, G.³ Melani, F.⁴ Palazzino, G.⁵ Martini, C.⁶ Giannaccini, G.⁷ Lucacchini, A.⁸

10
- 56749163600
- S.M. Hanson, E.V. Morlock, K.A. Satyshur, and C. Czajkowski J. Med. Chem. 51 2008 7243 7252
- (2008) J. Med. Chem. , vol.51 , pp. 7243-7252
- Hanson, S.M.¹ Morlock, E.V.² Satyshur, K.A.³ Czajkowski, C.⁴

11
- 67650815229
- D. Berezhnoy, T.T. Gibbs, and D.H. Farb Mol Pharmacol. 76 2009 440 450
- (2009) Mol Pharmacol. , vol.76 , pp. 440-450
- Berezhnoy, D.¹ Gibbs, T.T.² Farb, D.H.³

12
- 84859881146
- L. Richter, C. de Graaf, W. Sieghart, Z. Varagic, M. Mörzinger, I. J. P. de Esch, G. F. Ecker, and M. Ernst. Nat. Chem. Biol. 8 (2012) 455-464.
- (2012) Nat. Chem. Biol. , vol.8 , pp. 455-464
- Richter, L.¹

13
- 77954548982
- C. Alberti, and C. Tironi Il Farmaco-Ed. Sci. 19 1964 618 637
- (1964) Il Farmaco-Ed. Sci. , vol.19 , pp. 618-637
- Alberti, C.¹ Tironi, C.²

14
- 84864415890
- C. Alberti, and C. Tironi Il Farmaco-Ed. Sci. 19 1964 638651
- (1964) Il Farmaco-Ed. Sci. , vol.19 , pp. 638651
- Alberti, C.¹ Tironi, C.²

15
- 0002714675
- W.C. Still, M. Kahn, and A. Mitra J. Org. Chem. 43 1978 2923 2925
- (1978) J. Org. Chem. , vol.43 , pp. 2923-2925
- Still, W.C.¹ Kahn, M.² Mitra, A.³

16
- 84985234225
- S. Plescia, G. Daidone, V. Sprio, E. Aiello, G. Dattolo, and G. Cirrincione J. Heterocycl. Chem. 15 1978 1287 1290
- (1978) J. Heterocycl. Chem. , vol.15 , pp. 1287-1290
- Plescia, S.¹ Daidone, G.² Sprio, V.³ Aiello, E.⁴ Dattolo, G.⁵ Cirrincione, G.⁶

17
- 0000604488
- A. Altomare, M.C. Burla, M. Camalli, G. Cascarano, C. Giacovazzo, A. Gagliardi, and G. Polidori J. Appl. Crystallogr. 27 1994 435
- (1994) J. Appl. Crystallogr. , vol.27 , pp. 435
- Altomare, A.¹ Burla, M.C.² Camalli, M.³ Cascarano, G.⁴ Giacovazzo, C.⁵ Gagliardi, A.⁶ Polidori, G.⁷

18
- 0003517974
- University of Göttingen Germany
- G.M. Sheldrick SHELX-97, Program for Crystal Structure Refinement 1997 University of Göttingen Germany
- (1997) SHELX-97, Program for Crystal Structure Refinement
- Sheldrick, G.M.¹

19
- 0141452964
- G.X. Win, and J.L. Farrugia J. Appl. Cryst. 32 1999 837 838
- (1999) J. Appl. Cryst. , vol.32 , pp. 837-838
- Win, G.X.¹ Farrugia, J.L.²

20
- 0001117612
- M. Nardelli J. Appl. Crystallogr. 28 1995 659
- (1995) J. Appl. Crystallogr. , vol.28 , pp. 659
- Nardelli, M.¹

21
- 7544226311
- PRODRG: A tool for high-throughput crystallography of protein-ligand complexes
- DOI 10.1107/S0907444904011679
- A.W. Schüttelkopf, and D.M.F. van Aalten PRODRG - a tool for high-throughput crystallography of protein-ligand complexes Acta Crystallogr. D60 2004 1355 1363 (Pubitemid 41079731)
- (2004) Acta Crystallographica Section D: Biological Crystallography , vol.60 , Issue.8 , pp. 1355-1363
- Schuttelkopf, A.W.¹ Van Aalten, D.M.F.²

22
- 33744826819
- R. Thomsen, and M.H. Christensen J. Med. Chem. 49 2006 3315 3321
- (2006) J. Med. Chem. , vol.49 , pp. 3315-3321
- Thomsen, R.¹ Christensen, M.H.²

23
- 84872430712
- Hoegh-Guldbergs Gade 10, Bldg. 1090, DK-8000 Aarhus C, Denmark)
- Molegro ApS, Hoegh-Guldbergs Gade 10, Bldg. 1090, DK-8000 Aarhus C, Denmark).
- Molegro ApS

24
- 0028695270
- J.G. Vinter J. Comp-Aid. Mol. Des. 8 1994 653 668
- (1994) J. Comp-Aid. Mol. Des. , vol.8 , pp. 653-668
- Vinter, J.G.¹

25
- 0030255292
- J.G. Vinter J. Comp-Aid. Mol. Des. 10 1996 417 426
- (1996) J. Comp-Aid. Mol. Des. , vol.10 , pp. 417-426
- Vinter, J.G.¹

26
- 76149120388
- O. Trott, and A.J. Olson J. Comp. Chem. 31 2010 455 461
- (2010) J. Comp. Chem. , vol.31 , pp. 455-461
- Trott, O.¹ Olson, A.J.²

27
- 0022645046
- F. Melani, L. Cecchi, G. Palazzino, G. Filacchioni, C. Martini, E. Pennacchi, and A. Lucacchini J. Med. Chem. 29 1986 291 295
- (1986) J. Med. Chem. , vol.29 , pp. 291-295
- Melani, F.¹ Cecchi, L.² Palazzino, G.³ Filacchioni, G.⁴ Martini, C.⁵ Pennacchi, E.⁶ Lucacchini, A.⁷

28
- 71849104860
- O.H. Lovry, N.J. Roserbrough, A.L. Farr, and R.J. Randall J. Biol. Chem. 193 1951 265 275
- (1951) J. Biol. Chem. , vol.193 , pp. 265-275
- Lovry, O.H.¹ Roserbrough, N.J.² Farr, A.L.³ Randall, R.J.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.