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Volumn 24, Issue 15, 2014, Pages 3321-3325
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Structure-guided discovery of 1,3,5-triazine-pyrazole conjugates as antibacterial and antibiofilm agent against pathogens causing human diseases with favorable metabolic fate
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Author keywords
1,3,5 Triazine; Antibacterial; In silico studies; Pyrazole
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Indexed keywords
ANTIINFECTIVE AGENT;
CEFIXIME;
PYRAZOLE DERIVATIVE;
TRIAZINE DERIVATIVE;
VANCOMYCIN;
ANTIBIOTIC AGENT;
PYRAZOLE;
TRIAZINE;
ANTIBACTERIAL ACTIVITY;
ARTICLE;
BACILLUS CEREUS;
BACILLUS SUBTILIS;
BIOFILM;
CONTROLLED STUDY;
DRUG DESIGN;
DRUG METABOLISM;
DRUG STRUCTURE;
EPOXIDATION;
ESCHERICHIA COLI;
HYDROLYSIS;
HYDROXYLATION;
MINIMUM INHIBITORY CONCENTRATION;
NONHUMAN;
POLYMERIZATION;
PREDICTION;
PROTEUS VULGARIS;
PSEUDOMONAS AERUGINOSA;
REACTION ANALYSIS;
STAPHYLOCOCCUS AUREUS;
STRUCTURE ACTIVITY RELATION;
TOXICITY TESTING;
CHEMICAL STRUCTURE;
CHEMISTRY;
DOSE RESPONSE;
DRUG DEVELOPMENT;
DRUG EFFECTS;
GRAM NEGATIVE BACTERIUM;
GRAM POSITIVE BACTERIUM;
HUMAN;
METABOLISM;
MICROBIAL SENSITIVITY TEST;
DRUG CONJUGATION;
DRUG HYDROXYLATION;
DRUG POTENCY;
DRUG SYNTHESIS;
MICROBIAL DIVERSITY;
PATHOGENESIS;
PROTON TRANSPORT;
NEGIBACTERIA;
POSIBACTERIA;
ANTI-BACTERIAL AGENTS;
BIOFILMS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DRUG DISCOVERY;
GRAM-NEGATIVE BACTERIA;
GRAM-POSITIVE BACTERIA;
HUMANS;
MICROBIAL SENSITIVITY TESTS;
MOLECULAR STRUCTURE;
PYRAZOLES;
STRUCTURE-ACTIVITY RELATIONSHIP;
TRIAZINES;
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EID: 84904052757
PISSN: 0960894X
EISSN: 14643405
Source Type: Journal
DOI: 10.1016/j.bmcl.2014.05.103 Document Type: Article |
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Times cited : (59)
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References (16)
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