A new class of phenylhydrazinylidene derivatives as inhibitors of Staphylococcus aureus biofilm formation

Medicinal Chemistry Research

Volumn 25, Issue 5, 2016, Pages 870-878

  Cascioferro, Stella ^a,b   Maggio, Benedetta ^a   Raffa, Demetrio ^a   Raimondi, Maria Valeria ^a   Cusimano, Maria Grazia ^a   Schillaci, Domenico ^a   Manachini, Barbara ^a   Leonchiks, Ainars ^c   Daidone, Giuseppe ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b Istituto EuroMediterraneo di Scienza e Tecnologia   (Italy)

^c LATVIAN BIOMEDICAL RESEARCH AND STUDY CENTRE   (Latvia)

Author keywords

Antibiofilm agents; Antivirulence agents; Bacterial adhesion; Phenylhydrazinylidene derivatives; Sortase A

Indexed keywords

2 [2 (2,6 DIFLUOROPHENYL)HYDRAZINYLIDENE] 3 (5 METHYL 1, 2 OXAZOL 3 YL) 3 OXOPROPANOIC ACID; 2 [2 (3,4 DICHLOROPHENYL)HYDRAZINYLIDENE] 3 (1 ETHYL 3 METHYL 1H PYRAZOL 5 YL) 3 OXOPROPANOIC ACID; 2 [2 (3,4 DICHLOROPHENYL)HYDRAZINYLIDENE] 3 (5 METHYL 1,2 OXAZOL 3 YL) 3 OXOPROPANOIC ACID; 3 (5 METHYL 1,2 OXAZOL 3 YL) 2 [2 (2 NITROPHENYL)HYDRAZINYLIDENE] 3 OXOPROPANOIC ACID; 3 (5 METHYL 1,2 OXAZOL 3 YL) 2 [2 (4 NITROPHENYL)HYDRAZINYLIDENE] 3 OXOPROPANOIC ACID; ANTIBIOTIC AGENT; DEUTERIUM OXIDE; DIAZONIUM COMPOUND; ESTER DERIVATIVE; ETHYL 2 [2 (2,6 DIFLUOROPHENYL)HYDRAZINYLIDENE] 3 (1 ETHYL 3 METHYL 1H PYRAZOL 5 YL) 3 OXOPROPANOATE; ETHYL 2 [2 (2,6 DIFLUOROPHENYL)HYDRAZINYLIDENE] 3 (5 METHYL 1,2 OXAZOL 3 YL) 3 OXOPROPANOATE; ETHYL 2 [2 (3,4 DICHLOROPHENYL)HYDRAZINYLIDENE] 3 (1 ETHYL 3 METHYL 1H PYRAZOL 5 YL) 3 OXOPROPANOATE; ETHYL 2 [2 (3,4 DICHLOROPHENYL)HYDRAZINYLIDENE] 3 (5 METHYL 1,2 OXAZOL 3 YL) 3 OXOPROPANOATE; ETHYL 3 (5 METHYL 1,2 OXAZOL 3 YL) 2 [2 (2 NITROPHENYL)HYDRAZINYLIDENE] 3 OXOPROPANOATE; ETHYL 3 (5 METHYL 1,2 OXAZOL 3 YL) 2 [2 (4 NITROPHENYL)HYDRAZINYLIDENE] 3 OXOPROPANOATE; GAMMA GLUTAMYLTRANSFERASE; PHENYLHYDRAZONE DERIVATIVE; SORTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOFILM; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME INHIBITION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GALLERIA MELLONELLA; IC50; INFRARED SPECTROSCOPY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS;

EID: 84959148714     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-016-1535-9     Document Type: Article

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