Synthetic recombinase-based State machines in living cells

Science

Volumn 353, Issue 6297, 2016, Pages

  Roquet, Nathaniel ^a,b,c,d   Soleimany, Ava P ^a,b,c   Ferris, Alyssa C ^a,b,c,e   Aaronson, Scott ^c   Lu, Timothy K ^a,b,c,d  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c USA   (United States)

^d HARVARD UNIVERSITY   (United States)

^e WELLESLEY COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DINUCLEOTIDE; GREEN FLUORESCENT PROTEIN; RECOMBINASE; RNA POLYMERASE; DNA;

BIOENGINEERING; CELLS AND CELL COMPONENTS; COLIFORM BACTERIUM; DNA; ENZYME ACTIVITY; GENE EXPRESSION; RECOMBINATION;

ARTICLE; BIOENGINEERING; BIOINFORMATICS; CELL DIFFERENTIATION; CELL FUNCTION; CELL LINEAGE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONCEPTUAL FRAMEWORK; DNA REPLICATION ORIGIN; DNA SEQUENCE; ESCHERICHIA COLI; FLOW CYTOMETRY; FOUR GENE REGULATION; GENE CONTROL; GENE EXPRESSION; HUMAN; INFORMATION SCIENCE; MATHEMATICAL MODEL; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; RECOMBINASE BASED STATE MACHINE; SANGER SEQUENCING; SEQUENCE ANALYSIS; SINGLE GENE REGULATION; STEM CELL; TWO GENE REGULATION; CELLS; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GENETICS; MOLECULAR COMPUTER; NUCLEOTIDE SEQUENCE; SYNTHETIC BIOLOGY;

ESCHERICHIA COLI;

BASE SEQUENCE; CELLS; COMPUTERS, MOLECULAR; DNA; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; RECOMBINASES; SYNTHETIC BIOLOGY;

EID: 84979524762     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad8559     Document Type: Article

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