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Volumn 17, Issue 12, 2016, Pages 1611-1622

Treatment and prevention of cytomegalovirus infection in heart and lung transplantation: an update

Author keywords

Cytomegalovirus; ganciclovir; heart transplant; lung transplant; prevention; therapy

Indexed keywords

ACICLOVIR; ACICLOVIR TRIPHOSPHATE; BRINCIDOFOVIR; CIDOFOVIR; CYTOMEGALOVIRUS ANTIBODY; FOSCARNET; GANCICLOVIR; VALGANCICLOVIR; ANTIVIRUS AGENT; IMMUNOSUPPRESSIVE AGENT; VIRUS ANTIBODY;

EID: 84979300132     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1080/14656566.2016.1199684     Document Type: Review
Times cited : (28)

References (119)
  • 1
    • 34250660941 scopus 로고    scopus 로고
    • Frequent occult infection with Cytomegalovirus in cardiac transplant recipients despite antiviral prophylaxis
    • L.Potena, C.T.Holweg, M.L.Vana, et al. Frequent occult infection with Cytomegalovirus in cardiac transplant recipients despite antiviral prophylaxis. J Clin Microbiol. 2007;45:1804–1810.
    • (2007) J Clin Microbiol , vol.45 , pp. 1804-1810
    • Potena, L.1    Holweg, C.T.2    Vana, M.L.3
  • 2
    • 84883455574 scopus 로고    scopus 로고
    • Updated international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation
    • C.N.Kotton, D.Kumar, A.M.Caliendo, et al. Updated international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation. Transplantation. 2013;96:333–360.• This document represents an important reference point for CMV management and its supportive evidences.
    • (2013) Transplantation , vol.96 , pp. 333-360
    • Kotton, C.N.1    Kumar, D.2    Caliendo, A.M.3
  • 4
    • 0036646149 scopus 로고    scopus 로고
    • Immunomodulation by cytomegaloviruses: manipulative strategies beyond evasion
    • E.S.MocarskiJr. Immunomodulation by cytomegaloviruses: manipulative strategies beyond evasion. Trends Microbiol. 2002;10:332–339.
    • (2002) Trends Microbiol , vol.10 , pp. 332-339
    • Mocarski, E.S.1
  • 5
    • 4644252994 scopus 로고    scopus 로고
    • Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase
    • S.B.Kudchodkar, Y.Yu, T.G.Maguire, et al. Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase. J Virol. 2004;78:11030–11039.
    • (2004) J Virol , vol.78 , pp. 11030-11039
    • Kudchodkar, S.B.1    Yu, Y.2    Maguire, T.G.3
  • 6
    • 14044278803 scopus 로고    scopus 로고
    • Clinical and immunologic aspects of cytomegalovirus infection in solid organ transplant recipients
    • Rowshani AT, Bemelman FJ, van Leeuwen EM, van Lier RA, ten Berge IJ. Clinical and immunologic aspects of cytomegalovirus infection in solid organ transplant recipients. Transplantation. 2005;79:381–386.
    • (2005) Transplantation , vol.79 , pp. 381-386
  • 7
    • 68349131578 scopus 로고    scopus 로고
    • Long-term outcomes of cytomegalovirus infection and disease after lung or heart-lung transplantation with a delayed ganciclovir regimen
    • L.D.Thomas, A.P.Milstone, G.G.Miller, et al. Long-term outcomes of cytomegalovirus infection and disease after lung or heart-lung transplantation with a delayed ganciclovir regimen. Clin Transplant. 2009;23:476–483.
    • (2009) Clin Transplant , vol.23 , pp. 476-483
    • Thomas, L.D.1    Milstone, A.P.2    Miller, G.G.3
  • 8
    • 34347386490 scopus 로고    scopus 로고
    • Cytomegalovirus-associated allograft rejection in heart transplant patients
    • L.Potena, H.A.Valantine. Cytomegalovirus-associated allograft rejection in heart transplant patients. Curr Opin Infect Dis. 2007;20:425–431.
    • (2007) Curr Opin Infect Dis , vol.20 , pp. 425-431
    • Potena, L.1    Valantine, H.A.2
  • 9
    • 84927642861 scopus 로고    scopus 로고
    • Viral infections in lung transplant recipients: devils or trolls?
    • P.Solidoro, E.Balestro, M.Boffini. Viral infections in lung transplant recipients: devils or trolls? Minerva Med. 2014;105(Suppl 2–3):15–21.
    • (2014) Minerva Med
    • Solidoro, P.1    Balestro, E.2    Boffini, M.3
  • 10
    • 77952723344 scopus 로고    scopus 로고
    • Respiratory viral infections in transplant and oncology patients
    • D.Kumar, A.Humar. Respiratory viral infections in transplant and oncology patients. Infect Dis Clin North Am. 2010;24:395–412.
    • (2010) Infect Dis Clin North Am , vol.24 , pp. 395-412
    • Kumar, D.1    Humar, A.2
  • 11
    • 79953864833 scopus 로고    scopus 로고
    • Update and review: state-of-the-art management of cytomegalovirus infection and disease following thoracic organ transplantation
    • D.R.Snydman, A.P.Limaye, L.Potena, et al. Update and review: state-of-the-art management of cytomegalovirus infection and disease following thoracic organ transplantation. Transplant Proc. 2011;43:S1–S17.
    • (2011) Transplant Proc , vol.43 , pp. S1-S17
    • Snydman, D.R.1    Limaye, A.P.2    Potena, L.3
  • 12
    • 0022461410 scopus 로고
    • Synthesis and antiherpes virus activity of phosphate and phosphonate derivatives of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine
    • E.J.Prisbe, J.C.Martin, D.P.McGee, et al. Synthesis and antiherpes virus activity of phosphate and phosphonate derivatives of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine. J Med Chem. 1986;29:671–675.
    • (1986) J Med Chem , vol.29 , pp. 671-675
    • Prisbe, E.J.1    Martin, J.C.2    McGee, D.P.3
  • 13
    • 0036789258 scopus 로고    scopus 로고
    • Ganciclovir-resistant cytomegalovirus in organ transplant recipients
    • A.P.Limaye. Ganciclovir-resistant cytomegalovirus in organ transplant recipients. Clin Infect Dis. 2002;35:866–872.
    • (2002) Clin Infect Dis , vol.35 , pp. 866-872
    • Limaye, A.P.1
  • 14
    • 78049355534 scopus 로고    scopus 로고
    • Antiviral drug resistance of human cytomegalovirus
    • N.S.Lurain, S.Chou. Antiviral drug resistance of human cytomegalovirus. Clin Microbiol Rev. 2010;23:689–712.
    • (2010) Clin Microbiol Rev , vol.23 , pp. 689-712
    • Lurain, N.S.1    Chou, S.2
  • 15
    • 84875510406 scopus 로고    scopus 로고
    • Pre-emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant recipients
    • O.Ds, A.C.Webster, G.F.Strippoli, et al. Pre-emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant recipients. Cochrane Database Syst Rev. 2013;2:CD005133.•• A very extensive and comprehensive systematic review dissecting the evidences supporting preemptive anti-CMV strategies in solid organ transplantation.
    • (2013) Cochrane Database Syst Rev , vol.2 , pp. CD005133
    • Ds, O.1    Webster, A.C.2    Strippoli, G.F.3
  • 16
    • 84875538702 scopus 로고    scopus 로고
    • Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients
    • H.Em, M.Ladhani, A.C.Webster, et al. Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients. Cochrane Database Syst Rev. 2013;2:CD003774.•• This important paper is a companion to the one referenced at [15]. Here, the Cochrane group performs a complex and extensive meta-analysis of studies on CMV prophylaxis versus placebo or comparing different prophylaxis regiments. It is one of the few available papers providing evidences in the comparison among different antiviral treatments.
    • (2013) Cochrane Database Syst Rev , vol.2 , pp. CD003774
    • Em, H.1    Ladhani, M.2    Webster, A.C.3
  • 17
    • 8144231380 scopus 로고    scopus 로고
    • Pre-emptive treatment with oral valganciclovir in management of CMV infection after cardiac transplantation
    • E.Devyatko, A.Zuckermann, M.Ruzicka, et al. Pre-emptive treatment with oral valganciclovir in management of CMV infection after cardiac transplantation. J Heart Lung Transplant. 2004;23:1277–1282.
    • (2004) J Heart Lung Transplant , vol.23 , pp. 1277-1282
    • Devyatko, E.1    Zuckermann, A.2    Ruzicka, M.3
  • 18
    • 1942469969 scopus 로고    scopus 로고
    • Efficacy and safety of valganciclovir vs. Oral Ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients
    • C.Paya, A.Humar, E.Dominguez, et al. Efficacy and safety of valganciclovir vs. Oral Ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients. Am J Transplant. 2004;4:611–620.
    • (2004) Am J Transplant , vol.4 , pp. 611-620
    • Paya, C.1    Humar, A.2    Dominguez, E.3
  • 19
    • 34547829434 scopus 로고    scopus 로고
    • Oral valganciclovir is noninferior to intravenous ganciclovir for the treatment of cytomegalovirus disease in solid organ transplant recipients
    • A.Asberg, A.Humar, H.Rollag, et al. Oral valganciclovir is noninferior to intravenous ganciclovir for the treatment of cytomegalovirus disease in solid organ transplant recipients. Am J Transplant. 2007;7:2106–2113.
    • (2007) Am J Transplant , vol.7 , pp. 2106-2113
    • Asberg, A.1    Humar, A.2    Rollag, H.3
  • 20
    • 84920181776 scopus 로고    scopus 로고
    • Subtherapeutic ganciclovir (GCV) levels and GCV-resistant cytomegalovirus in lung transplant recipients
    • J.P.Gagermeier, J.D.Rusinak, N.S.Lurain, et al. Subtherapeutic ganciclovir (GCV) levels and GCV-resistant cytomegalovirus in lung transplant recipients. Transpl Infect Dis. 2014;16:941–950.• Very interesting study analyzing the relationship between valganciclovir blood concentrations with CMV kinetics in lung transplant recipients.
    • (2014) Transpl Infect Dis , vol.16 , pp. 941-950
    • Gagermeier, J.P.1    Rusinak, J.D.2    Lurain, N.S.3
  • 21
    • 0034608956 scopus 로고    scopus 로고
    • Prediction of cytomegalovirus load and resistance patterns after antiviral chemotherapy
    • V.C.Emery, P.D.Griffiths. Prediction of cytomegalovirus load and resistance patterns after antiviral chemotherapy. Proc Natl Acad Sci USA. 2000;97:8039–8044.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8039-8044
    • Emery, V.C.1    Griffiths, P.D.2
  • 22
    • 0034933929 scopus 로고    scopus 로고
    • Ganciclovir: an update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients
    • J.K.McGavin, K.L.Goa. Ganciclovir: an update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients. Drugs. 2001;61:1153–1183.
    • (2001) Drugs , vol.61 , pp. 1153-1183
    • McGavin, J.K.1    Goa, K.L.2
  • 23
    • 84880132320 scopus 로고    scopus 로고
    • International survey of cytomegalovirus management in solid organ transplantation after the publication of consensus guidelines
    • A.K.Le Page, M.M.Jager, C.N.Kotton, et al. International survey of cytomegalovirus management in solid organ transplantation after the publication of consensus guidelines. Transplantation. 2013;95:1455–1460.
    • (2013) Transplantation , vol.95 , pp. 1455-1460
    • Le Page, A.K.1    Jager, M.M.2    Kotton, C.N.3
  • 24
    • 77950468641 scopus 로고    scopus 로고
    • The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients
    • A.Humar, Y.Lebranchu, F.Vincenti, et al. The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients. Am J Transplant. 2010;10:1228–1237.
    • (2010) Am J Transplant , vol.10 , pp. 1228-1237
    • Humar, A.1    Lebranchu, Y.2    Vincenti, F.3
  • 25
    • 77954070106 scopus 로고    scopus 로고
    • Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: a randomized, controlled trial
    • Palmer SM, Limaye AP, Banks M, et al. Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: a randomized, controlled trial. Ann Intern Med. 2010;152:761–769.
    • (2010) Ann Intern Med , vol.152 , pp. 761-769
  • 26
    • 51849151201 scopus 로고    scopus 로고
    • Prevention of posttransplant cytomegalovirus disease and related outcomes with valganciclovir: a systematic review
    • H.Y.Sun, M.M.Wagener, N.Singh. Prevention of posttransplant cytomegalovirus disease and related outcomes with valganciclovir: a systematic review. Am J Transplant. 2008;8:2111–2118.
    • (2008) Am J Transplant , vol.8 , pp. 2111-2118
    • Sun, H.Y.1    Wagener, M.M.2    Singh, N.3
  • 27
    • 65849405940 scopus 로고    scopus 로고
    • Valganciclovir for cytomegalovirus prevention in solid organ transplant patients: an evidence-based reassessment of safety and efficacy
    • A.C.Kalil, A.G.Freifeld, E.R.Lyden, et al. Valganciclovir for cytomegalovirus prevention in solid organ transplant patients: an evidence-based reassessment of safety and efficacy. PLoS One. 2009;4:e5512.
    • (2009) PLoS One , vol.4 , pp. 5512
    • Kalil, A.C.1    Freifeld, A.G.2    Lyden, E.R.3
  • 28
    • 79951822463 scopus 로고    scopus 로고
    • Effectiveness of valganciclovir 900 mg versus 450 mg for cytomegalovirus prophylaxis in transplantation: direct and indirect treatment comparison meta-analysis
    • A.C.Kalil, C.Mindru, D.F.Florescu. Effectiveness of valganciclovir 900 mg versus 450 mg for cytomegalovirus prophylaxis in transplantation: direct and indirect treatment comparison meta-analysis. Clin Infect Dis. 2011;52:313–321.
    • (2011) Clin Infect Dis , vol.52 , pp. 313-321
    • Kalil, A.C.1    Mindru, C.2    Florescu, D.F.3
  • 29
    • 79951839960 scopus 로고    scopus 로고
    • Low-dose valganciclovir for cytomegalovirus prophylaxis in organ transplantation: is less really more?
    • R.K.Avery. Low-dose valganciclovir for cytomegalovirus prophylaxis in organ transplantation: is less really more? Clin Infect Dis. 2011;52:322–324.
    • (2011) Clin Infect Dis , vol.52 , pp. 322-324
    • Avery, R.K.1
  • 30
    • 0021050383 scopus 로고
    • Use of acyclovir for prophylaxis of herpes infections in severely immunocompromised patients
    • H.G.Prentice. Use of acyclovir for prophylaxis of herpes infections in severely immunocompromised patients. J Antimicrob Chemother. 1983;12 (Suppl B):153–159.
    • (1983) J Antimicrob Chemother , vol.12 , pp. 153-159
    • Prentice, H.G.1
  • 31
    • 0021021517 scopus 로고
    • The use of acyclovir for cytomegalovirus infections in the immunocompromised host
    • J.D.Meyers, J.C.Wade, R.W.McGuffin, et al. The use of acyclovir for cytomegalovirus infections in the immunocompromised host. J Antimicrob Chemother. 1983;12(Suppl B):181–193.
    • (1983) J Antimicrob Chemother , vol.12 , pp. 181-193
    • Meyers, J.D.1    Wade, J.C.2    McGuffin, R.W.3
  • 32
    • 0033551348 scopus 로고    scopus 로고
    • Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group
    • D.Lowance, H.H.Neumayer, C.M.Legendre, et al. Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group. N Engl J Med 1999;340:1462–1470.
    • (1999) N Engl J Med , vol.340 , pp. 1462-1470
    • Lowance, D.1    Neumayer, H.H.2    Legendre, C.M.3
  • 33
    • 0032573740 scopus 로고    scopus 로고
    • A randomized prospective controlled trial of oral acyclovir versus oral ganciclovir for cytomegalovirus prophylaxis in high-risk kidney transplant recipients
    • S.M.Flechner, R.K.Avery, R.Fisher, et al. A randomized prospective controlled trial of oral acyclovir versus oral ganciclovir for cytomegalovirus prophylaxis in high-risk kidney transplant recipients. Transplantation. 1998;66:1682–1688.
    • (1998) Transplantation , vol.66 , pp. 1682-1688
    • Flechner, S.M.1    Avery, R.K.2    Fisher, R.3
  • 34
    • 0028346317 scopus 로고
    • A comparison of ganciclovir and acyclovir to prevent cytomegalovirus after lung transplantation
    • S.R.Duncan, W.F.Grgurich, A.T.Iacono, et al. A comparison of ganciclovir and acyclovir to prevent cytomegalovirus after lung transplantation. Am J Respir Crit Care Med. 1994;150:146–152.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 146-152
    • Duncan, S.R.1    Grgurich, W.F.2    Iacono, A.T.3
  • 35
    • 77957280871 scopus 로고    scopus 로고
    • An international survey of cytomegalovirus management practices in lung transplantation
    • D.M.Zuk, A.Humar, J.G.Weinkauf, et al. An international survey of cytomegalovirus management practices in lung transplantation. Transplantation. 2010;90:672–676.
    • (2010) Transplantation
    • Zuk, D.M.1    Humar, A.2    Weinkauf, J.G.3
  • 36
    • 37549024633 scopus 로고    scopus 로고
    • Valacyclovir prophylaxis versus preemptive valganciclovir therapy to prevent cytomegalovirus disease after renal transplantation
    • T.Reischig, P.Jindra, O.Hes, et al. Valacyclovir prophylaxis versus preemptive valganciclovir therapy to prevent cytomegalovirus disease after renal transplantation. Am J Transplant. 2008;8:69–77.
    • (2008) Am J Transplant , vol.8 , pp. 69-77
    • Reischig, T.1    Jindra, P.2    Hes, O.3
  • 37
    • 84923809198 scopus 로고    scopus 로고
    • Randomized trial of valganciclovir versus valacyclovir prophylaxis for prevention of cytomegalovirus in renal transplantation
    • T.Reischig, M.Kacer, P.Jindra, et al. Randomized trial of valganciclovir versus valacyclovir prophylaxis for prevention of cytomegalovirus in renal transplantation. Clin J Am Soc Nephrol: CJASN. 2015;10:294–304.
    • (2015) Clin J Am Soc Nephrol: CJASN , vol.10 , pp. 294-304
    • Reischig, T.1    Kacer, M.2    Jindra, P.3
  • 38
    • 84860796334 scopus 로고    scopus 로고
    • Pharmacoeconomic impact of different regimens to prevent cytomegalovirus infection in renal transplant recipients
    • L.Kielberger, M.Bouda, P.Jindra, et al. Pharmacoeconomic impact of different regimens to prevent cytomegalovirus infection in renal transplant recipients. Kidney Blood Press Res. 2012;35:407–416.
    • (2012) Kidney Blood Press Res , vol.35 , pp. 407-416
    • Kielberger, L.1    Bouda, M.2    Jindra, P.3
  • 39
    • 84865991144 scopus 로고    scopus 로고
    • Long-term outcomes of pre-emptive valganciclovir compared with valacyclovir prophylaxis for prevention of cytomegalovirus in renal transplantation
    • T.Reischig, P.Hribova, P.Jindra, et al. Long-term outcomes of pre-emptive valganciclovir compared with valacyclovir prophylaxis for prevention of cytomegalovirus in renal transplantation. J Am Soc Nephrol. 2012;23:1588–1597.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1588-1597
    • Reischig, T.1    Hribova, P.2    Jindra, P.3
  • 40
    • 84891538529 scopus 로고    scopus 로고
    • Ganciclovir-resistant cytomegalovirus infections among lung transplant recipients are associated with poor outcomes despite treatment with foscarnet-containing regimens
    • L.R.Minces, M.H.Nguyen, D.Mitsani, et al. Ganciclovir-resistant cytomegalovirus infections among lung transplant recipients are associated with poor outcomes despite treatment with foscarnet-containing regimens. Antimicrob Agents Chemother. 2014;58:128–135.• This study highlights the poor clinical outcomes of lung transplant recipients developing ganciclovir resistance, despite foscarnet treatment is effective in clearing off the infection.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 128-135
    • Minces, L.R.1    Nguyen, M.H.2    Mitsani, D.3
  • 41
    • 0034686916 scopus 로고    scopus 로고
    • Emergence of ganciclovir-resistant cytomegalovirus disease among recipients of solid-organ transplants
    • A.P.Limaye, L.Corey, D.M.Koelle, et al. Emergence of ganciclovir-resistant cytomegalovirus disease among recipients of solid-organ transplants. Lancet. 2000;356:645–649.
    • (2000) Lancet , vol.356 , pp. 645-649
    • Limaye, A.P.1    Corey, L.2    Koelle, D.M.3
  • 42
    • 0036137356 scopus 로고    scopus 로고
    • High incidence of ganciclovir-resistant cytomegalovirus infection among lung transplant recipients receiving preemptive therapy
    • A.P.Limaye, G.Raghu, D.M.Koelle, et al. High incidence of ganciclovir-resistant cytomegalovirus infection among lung transplant recipients receiving preemptive therapy. J Infect Dis. 2002;185:20–27.
    • (2002) J Infect Dis , vol.185 , pp. 20-27
    • Limaye, A.P.1    Raghu, G.2    Koelle, D.M.3
  • 43
    • 84864918311 scopus 로고    scopus 로고
    • Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient
    • V.Tischler, M.M.Schuurmans, A.Boehler, et al. Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient. J Heart Lung Transplant. 2012;31:1037–1040.
    • (2012) J Heart Lung Transplant , vol.31 , pp. 1037-1040
    • Tischler, V.1    Schuurmans, M.M.2    Boehler, A.3
  • 44
    • 41049108271 scopus 로고    scopus 로고
    • Emergence of drug-resistant cytomegalovirus in the era of valganciclovir prophylaxis: therapeutic implications and outcomes
    • A.J.Eid, S.K.Arthurs, P.J.Deziel, et al. Emergence of drug-resistant cytomegalovirus in the era of valganciclovir prophylaxis: therapeutic implications and outcomes. Clin Transplant. 2008;22:162–170.
    • (2008) Clin Transplant , vol.22 , pp. 162-170
    • Eid, A.J.1    Arthurs, S.K.2    Deziel, P.J.3
  • 45
    • 9044238842 scopus 로고    scopus 로고
    • The cytomegalovirus retreatment trial. the studies of ocular complications of AIDS research group in collaboration with the AIDS clinical trials group
    • Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS. The cytomegalovirus retreatment trial. the studies of ocular complications of AIDS research group in collaboration with the AIDS clinical trials group. Arch Ophthalmol. 1996;114:23–33.
    • (1996) Arch Ophthalmol , vol.114 , pp. 23-33
  • 46
    • 84876691654 scopus 로고    scopus 로고
    • Use of high-dose ganciclovir for the treatment of cytomegalovirus replication in solid organ transplant patients with ganciclovir resistance-inducing mutations
    • I.Gracia-Ahufinger, J.Gutierrez-Aroca, E.Cordero, et al. Use of high-dose ganciclovir for the treatment of cytomegalovirus replication in solid organ transplant patients with ganciclovir resistance-inducing mutations. Transplantation. 2013;95:1015–1020.
    • (2013) Transplantation , vol.95 , pp. 1015-1020
    • Gracia-Ahufinger, I.1    Gutierrez-Aroca, J.2    Cordero, E.3
  • 47
    • 84916887089 scopus 로고    scopus 로고
    • Insights into the mechanism of action of cidofovir and other acyclic nucleoside phosphonates against polyoma- and papillomaviruses and non-viral induced neoplasia
    • G.Andrei, D.Topalis, T.De Schutter, et al. Insights into the mechanism of action of cidofovir and other acyclic nucleoside phosphonates against polyoma- and papillomaviruses and non-viral induced neoplasia. Antiviral Res. 2015;114:21–46.
    • (2015) Antiviral Res , vol.114 , pp. 21-46
    • Andrei, G.1    Topalis, D.2    De Schutter, T.3
  • 49
    • 84868200175 scopus 로고    scopus 로고
    • Efficacy and safety of maribavir dosed at 100 mg orally twice daily for the prevention of cytomegalovirus disease in liver transplant recipients: a randomized, double-blind, multicenter controlled trial
    • D.J.Winston, F.Saliba, E.Blumberg, et al. Efficacy and safety of maribavir dosed at 100 mg orally twice daily for the prevention of cytomegalovirus disease in liver transplant recipients: a randomized, double-blind, multicenter controlled trial. Am J Transplant. 2012;12:3021–3030.
    • (2012) Am J Transplant , vol.12 , pp. 3021-3030
    • Winston, D.J.1    Saliba, F.2    Blumberg, E.3
  • 50
    • 84884528238 scopus 로고    scopus 로고
    • CMX001 to prevent cytomegalovirus disease in hematopoietic-cell transplantation
    • F.M.Marty, D.J.Winston, S.D.Rowley, et al. CMX001 to prevent cytomegalovirus disease in hematopoietic-cell transplantation. N Engl J Med. 2013;369:1227–1236.
    • (2013) N Engl J Med , vol.369 , pp. 1227-1236
    • Marty, F.M.1    Winston, D.J.2    Rowley, S.D.3
  • 51
    • 84899819902 scopus 로고    scopus 로고
    • Letermovir for cytomegalovirus prophylaxis in hematopoietic-cell transplantation
    • R.F.Chemaly, A.J.Ullmann, S.Stoelben, et al. Letermovir for cytomegalovirus prophylaxis in hematopoietic-cell transplantation. N Engl J Med. 2014;370:1781–1789.
    • (2014) N Engl J Med , vol.370 , pp. 1781-1789
    • Chemaly, R.F.1    Ullmann, A.J.2    Stoelben, S.3
  • 52
    • 84901363363 scopus 로고    scopus 로고
    • New cell-signaling pathways for controlling cytomegalovirus replication
    • S.Roy, R.Arav-Boger. New cell-signaling pathways for controlling cytomegalovirus replication. Am J Transplant. 2014;14:1249–1258.• Recommended review article providing an overview on potential novel therapeutic targets for CMV infection.
    • (2014) Am J Transplant , vol.14 , pp. 1249-1258
    • Roy, S.1    Arav-Boger, R.2
  • 53
    • 0033302594 scopus 로고    scopus 로고
    • Indirect effects of CMV in the solid organ transplant patient
    • C.V.Paya. Indirect effects of CMV in the solid organ transplant patient. Transpl Infect Dis. 1999;1(Suppl 1):8–12.
    • (1999) Transpl Infect Dis , vol.1 , pp. 8-12
    • Paya, C.V.1
  • 54
    • 84959917854 scopus 로고    scopus 로고
    • Cytomegalovirus immunoglobulin after thoracic transplantation: an overview
    • P.Grossi, P.Mohacsi, Z.Szabolcs, et al. Cytomegalovirus immunoglobulin after thoracic transplantation: an overview. Transplantation. 2016;100:s1–s3.
    • (2016) Transplantation , vol.100 , pp. s1-s3
    • Grossi, P.1    Mohacsi, P.2    Szabolcs, Z.3
  • 55
    • 73649119908 scopus 로고    scopus 로고
    • Intravenous immunoglobulin G: trends in production methods, quality control and quality assurance
    • M.Radosevich, T.Burnouf. Intravenous immunoglobulin G: trends in production methods, quality control and quality assurance. Vox Sang. 2010;98:12–28.
    • (2010) Vox Sang , vol.98 , pp. 12-28
    • Radosevich, M.1    Burnouf, T.2
  • 56
    • 84959882546 scopus 로고    scopus 로고
    • The immunology of posttransplant CMV infection: potential effect of CMV immunoglobulins on distinct components of the immune response to CMV
    • J.Carbone. The immunology of posttransplant CMV infection: potential effect of CMV immunoglobulins on distinct components of the immune response to CMV. Transplantation. 2016;100:S11–S8.
    • (2016) Transplantation , vol.100 , pp. S11-S118
    • Carbone, J.1
  • 57
    • 67649305136 scopus 로고    scopus 로고
    • Immune monitoring of anti cytomegalovirus antibodies and risk of cytomegalovirus disease in heart transplantation
    • E.Sarmiento, N.Lanio, A.Gallego, et al. Immune monitoring of anti cytomegalovirus antibodies and risk of cytomegalovirus disease in heart transplantation. Int Immunopharmacol. 2009;9:649–652.
    • (2009) Int Immunopharmacol , vol.9 , pp. 649-652
    • Sarmiento, E.1    Lanio, N.2    Gallego, A.3
  • 58
    • 27844535390 scopus 로고    scopus 로고
    • The impact of CytoGam on cardiac transplant recipients with moderate hypogammaglobulinemia: a randomized single-center study
    • M.H.Yamani, R.Avery, S.D.Mawhorter, et al. The impact of CytoGam on cardiac transplant recipients with moderate hypogammaglobulinemia: a randomized single-center study. J Heart Lung Transplant. 2005;24:1766–1769.
    • (2005) J Heart Lung Transplant , vol.24 , pp. 1766-1769
    • Yamani, M.H.1    Avery, R.2    Mawhorter, S.D.3
  • 59
    • 1842472928 scopus 로고    scopus 로고
    • Comparison of combined prophylaxis of cytomegalovirus hyperimmune globulin plus ganciclovir versus cytomegalovirus hyperimmune globulin alone in high-risk heart transplant recipients
    • N.E.Bonaros, A.Kocher, D.Dunkler, et al. Comparison of combined prophylaxis of cytomegalovirus hyperimmune globulin plus ganciclovir versus cytomegalovirus hyperimmune globulin alone in high-risk heart transplant recipients. Transplantation. 2004;77:890–897.
    • (2004) Transplantation , vol.77 , pp. 890-897
    • Bonaros, N.E.1    Kocher, A.2    Dunkler, D.3
  • 60
    • 0037489513 scopus 로고    scopus 로고
    • Impact of prophylaxis with cytogam alone on the incidence of CMV viremia in CMV-seropositive lung transplant recipients
    • R.M.Kruger, S.Paranjothi, G.A.Storch, et al. Impact of prophylaxis with cytogam alone on the incidence of CMV viremia in CMV-seropositive lung transplant recipients. J Heart Lung Transplant. 2003;22:754–763.
    • (2003) J Heart Lung Transplant , vol.22 , pp. 754-763
    • Kruger, R.M.1    Paranjothi, S.2    Storch, G.A.3
  • 61
    • 0025101475 scopus 로고
    • Cytomegalovirus seronegative heart transplant recipients. Prophylactic Use of Anti-Cmv Immunoglobulin
    • H.J.Metselaar, A.H.Balk, B.Mochtar, et al. Cytomegalovirus seronegative heart transplant recipients. Prophylactic Use of Anti-Cmv Immunoglobulin. Chest. 1990;97:396–399.
    • (1990) Chest , vol.97 , pp. 396-399
    • Metselaar, H.J.1    Balk, A.H.2    Mochtar, B.3
  • 62
    • 0027219694 scopus 로고
    • Passive immunization against cytomegalovirus in allograft recipients. The Rotterdam Heart Transplant Program experience
    • A.H.Balk, W.Weimar, P.H.Rothbarth, et al. Passive immunization against cytomegalovirus in allograft recipients. The Rotterdam Heart Transplant Program experience. Infection 1993;21:195–200.
    • (1993) Infection , vol.21 , pp. 195-200
    • Balk, A.H.1    Weimar, W.2    Rothbarth, P.H.3
  • 63
    • 33747118343 scopus 로고    scopus 로고
    • Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection
    • L.Potena, C.T.Holweg, C.Chin, et al. Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection. Transplantation. 2006;82:398–405.
    • (2006) Transplantation , vol.82 , pp. 398-405
    • Potena, L.1    Holweg, C.T.2    Chin, C.3
  • 64
    • 79952480236 scopus 로고    scopus 로고
    • Effect of CMV-immunoglobulins (cytotect biotest) prophylaxis on CMV pneumonia after lung transplantation
    • P.Solidoro, L.Delsedime, C.Costa, et al. Effect of CMV-immunoglobulins (cytotect biotest) prophylaxis on CMV pneumonia after lung transplantation. New Microbiol. 2011;34:33–36.
    • (2011) New Microbiol , vol.34 , pp. 33-36
    • Solidoro, P.1    Delsedime, L.2    Costa, C.3
  • 65
    • 48049120457 scopus 로고    scopus 로고
    • Combined cytomegalovirus prophylaxis in lung transplantation: effects on acute rejection, lymphocytic bronchitis/bronchiolitis, and herpesvirus infections
    • P.Solidoro, D.Libertucci, L.Delsedime, et al. Combined cytomegalovirus prophylaxis in lung transplantation: effects on acute rejection, lymphocytic bronchitis/bronchiolitis, and herpesvirus infections. Transplant Proc. 2008;40:2013–2014.
    • (2008) Transplant Proc , vol.40 , pp. 2013-2014
    • Solidoro, P.1    Libertucci, D.2    Delsedime, L.3
  • 66
    • 33744900344 scopus 로고    scopus 로고
    • Combined CMV prophylaxis improves outcome and reduces the risk for bronchiolitis obliterans syndrome (BOS) after lung transplantation
    • E.Ruttmann, C.Geltner, B.Bucher, et al. Combined CMV prophylaxis improves outcome and reduces the risk for bronchiolitis obliterans syndrome (BOS) after lung transplantation. Transplantation. 2006;81:1415–1420.
    • (2006) Transplantation , vol.81 , pp. 1415-1420
    • Ruttmann, E.1    Geltner, C.2    Bucher, B.3
  • 67
    • 0037990048 scopus 로고    scopus 로고
    • Combination prophylaxis with ganciclovir and cytomegalovirus (CMV) immune globulin after lung transplantation: effective CMV prevention following daclizumab induction
    • D.Weill, B.J.Lock, D.L.Wewers, et al. Combination prophylaxis with ganciclovir and cytomegalovirus (CMV) immune globulin after lung transplantation: effective CMV prevention following daclizumab induction. Am J Transplant. 2003;3:492–496.
    • (2003) Am J Transplant , vol.3 , pp. 492-496
    • Weill, D.1    Lock, B.J.2    Wewers, D.L.3
  • 68
    • 34548703848 scopus 로고    scopus 로고
    • The potential impact of substitutive therapy with intravenous immunoglobulin on the outcome of heart transplant recipients with infections
    • J.Carbone, E.Sarmiento, J.Palomo, et al. The potential impact of substitutive therapy with intravenous immunoglobulin on the outcome of heart transplant recipients with infections. Transplant Proc. 2007;39:2385–2388.
    • (2007) Transplant Proc , vol.39 , pp. 2385-2388
    • Carbone, J.1    Sarmiento, E.2    Palomo, J.3
  • 69
    • 67651027514 scopus 로고    scopus 로고
    • Intravenous immunoglobulin a natural regulator of immunity and inflammation
    • S.C.Jordan, M.Toyoda, A.A.Vo. Intravenous immunoglobulin a natural regulator of immunity and inflammation. Transplantation. 2009;88:1–6.
    • (2009) Transplantation , vol.88 , pp. 1-6
    • Jordan, S.C.1    Toyoda, M.2    Vo, A.A.3
  • 70
    • 84959904055 scopus 로고    scopus 로고
    • CMV immunoglobulins for the treatment of cmv infections in thoracic transplant recipients
    • U.Shulz, P.Solidoro, V.Muller, et al. CMV immunoglobulins for the treatment of cmv infections in thoracic transplant recipients. Transplantation. 2016;100:S5–S10.
    • (2016) Transplantation , vol.100 , pp. S5-S10
    • Shulz, U.1    Solidoro, P.2    Muller, V.3
  • 71
    • 77954920888 scopus 로고    scopus 로고
    • Effects of the intensity of immunosuppressive therapy on outcome of treatment for CMV disease in organ transplant recipients
    • A.Asberg, A.G.Jardine, A.A.Bignamini, et al. Effects of the intensity of immunosuppressive therapy on outcome of treatment for CMV disease in organ transplant recipients. Am J Transplant. 2010;10:1881–1888.
    • (2010) Am J Transplant , vol.10 , pp. 1881-1888
    • Asberg, A.1    Jardine, A.G.2    Bignamini, A.A.3
  • 72
    • 37349084974 scopus 로고    scopus 로고
    • A lower incidence of cytomegalovirus infection in de novo heart transplant recipients randomized to everolimus
    • Hill JA, Hummel M, Starling RC, et al. A lower incidence of cytomegalovirus infection in de novo heart transplant recipients randomized to everolimus. Transplantation. 2007;84:1436–1442.
    • (2007) Transplantation , vol.84 , pp. 1436-1442
  • 73
    • 84892942619 scopus 로고    scopus 로고
    • Interaction of CMV prophylaxis and pre-emptive strategies with immunosuppressive therapy: potential antiviral effect of everolimus
    • L.Potena, C.D’Agostino, D.Abate, et al. Interaction of CMV prophylaxis and pre-emptive strategies with immunosuppressive therapy: potential antiviral effect of everolimus. J Heart Lung Transplant. 2010;29:S155–S6.
    • (2010) J Heart Lung Transplant , vol.29 , pp. S155-S166
    • Potena, L.1    D’Agostino, C.2    Abate, D.3
  • 74
    • 84876930437 scopus 로고    scopus 로고
    • Everolimus versus mycophenolate mofetil in heart transplantation: a randomized, multicenter trial
    • Eisen HJ, Kobashigawa J, Starling RC, et al. Everolimus versus mycophenolate mofetil in heart transplantation: a randomized, multicenter trial. Am J Transplant. 2013;13:1203–1216.
    • (2013) Am J Transplant , vol.13 , pp. 1203-1216
  • 75
    • 84875942737 scopus 로고    scopus 로고
    • Everolimus is associated with a reduced incidence of cytomegalovirus infection following de novo cardiac transplantation
    • J.Kobashigawa, H.Ross, C.Bara, et al. Everolimus is associated with a reduced incidence of cytomegalovirus infection following de novo cardiac transplantation. Transpl Infect Dis. 2013;15:150–162.
    • (2013) Transpl Infect Dis , vol.15 , pp. 150-162
    • Kobashigawa, J.1    Ross, H.2    Bara, C.3
  • 76
    • 84862290097 scopus 로고    scopus 로고
    • Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients
    • B.Nashan, R.Gaston, V.Emery, et al. Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients. Transplantation. 2012;93:1075–1085.
    • (2012) Transplantation , vol.93 , pp. 1075-1085
    • Nashan, B.1    Gaston, R.2    Emery, V.3
  • 77
    • 84874718381 scopus 로고    scopus 로고
    • Effect of maintenance immunosuppressive drugs on virus pathobiology: evidence and potential mechanisms
    • D.C.Brennan, J.M.Aguado, L.Potena, et al. Effect of maintenance immunosuppressive drugs on virus pathobiology: evidence and potential mechanisms. Rev Med Virol. 2013;23:97–125.
    • (2013) Rev Med Virol , vol.23 , pp. 97-125
    • Brennan, D.C.1    Aguado, J.M.2    Potena, L.3
  • 78
    • 45449112352 scopus 로고    scopus 로고
    • Reduced risk of cytomegalovirus infection in solid organ transplant recipients treated with sirolimus: a pooled analysis of clinical trials
    • L.Demopoulos, M.Polinsky, G.Steele, et al. Reduced risk of cytomegalovirus infection in solid organ transplant recipients treated with sirolimus: a pooled analysis of clinical trials. Transplant Proc. 2008;40:1407–1410.
    • (2008) Transplant Proc , vol.40 , pp. 1407-1410
    • Demopoulos, L.1    Polinsky, M.2    Steele, G.3
  • 79
    • 79952844950 scopus 로고    scopus 로고
    • The changing role of mTOR kinase in the maintenance of protein synthesis during human cytomegalovirus infection
    • A.J.Clippinger, T.G.Maguire, J.C.Alwine. The changing role of mTOR kinase in the maintenance of protein synthesis during human cytomegalovirus infection. J Virol. 2011;85:3930–3939.
    • (2011) J Virol , vol.85 , pp. 3930-3939
    • Clippinger, A.J.1    Maguire, T.G.2    Alwine, J.C.3
  • 80
    • 79954623272 scopus 로고    scopus 로고
    • A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity
    • Q.Li, R.R.Rao, K.Araki, et al. A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity. Immunity. 2011;34:541–553.
    • (2011) Immunity , vol.34 , pp. 541-553
    • Li, Q.1    Rao, R.R.2    Araki, K.3
  • 81
    • 77951678634 scopus 로고    scopus 로고
    • The role of mTOR in memory CD8 T-cell differentiation
    • K.Araki, B.Youngblood, R.Ahmed. The role of mTOR in memory CD8 T-cell differentiation. Immunol Rev. 2010;235:234–243.
    • (2010) Immunol Rev , vol.235 , pp. 234-243
    • Araki, K.1    Youngblood, B.2    Ahmed, R.3
  • 82
    • 84861818332 scopus 로고    scopus 로고
    • CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages
    • M.Poglitsch, T.Weichhart, M.Hecking, et al. CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages. Am J Transplant. 2012;12:1458–1468.
    • (2012) Am J Transplant , vol.12 , pp. 1458-1468
    • Poglitsch, M.1    Weichhart, T.2    Hecking, M.3
  • 83
    • 84873566763 scopus 로고    scopus 로고
    • Recommendations on the use of everolimus in lung transplantation
    • A.De Pablo, F.Santos, A.Sole, et al. Recommendations on the use of everolimus in lung transplantation. Transplant Rev (Orlando). 2013;27:9–16.
    • (2013) Transplant Rev (Orlando) , vol.27 , pp. 9-16
    • De Pablo, A.1    Santos, F.2    Sole, A.3
  • 84
    • 84912034783 scopus 로고    scopus 로고
    • Everolimus-based immunosuppressive regimens in lung transplant recipients: impact on CMV infection
    • M.Ritta, C.Costa, P.Solidoro, et al. Everolimus-based immunosuppressive regimens in lung transplant recipients: impact on CMV infection. Antiviral Res. 2015;113:19–26.
    • (2015) Antiviral Res , vol.113 , pp. 19-26
    • Ritta, M.1    Costa, C.2    Solidoro, P.3
  • 85
    • 84919977042 scopus 로고    scopus 로고
    • Three-year results of an investigator-driven multicenter, international, randomized open-label de novo trial to prevent BOS after lung transplantation
    • A.R.Glanville, C.Aboyoun, W.Klepetko, et al. Three-year results of an investigator-driven multicenter, international, randomized open-label de novo trial to prevent BOS after lung transplantation. J Heart Lung Transplant. 2015;34:16–25.
    • (2015) J Heart Lung Transplant , vol.34 , pp. 16-25
    • Glanville, A.R.1    Aboyoun, C.2    Klepetko, W.3
  • 86
    • 33745288559 scopus 로고    scopus 로고
    • Wound healing complications with de novo sirolimus versus mycophenolate mofetil-based regimen in cardiac transplant recipients
    • S.Kuppahally, A.Al-Khaldi, D.Weisshaar, et al. Wound healing complications with de novo sirolimus versus mycophenolate mofetil-based regimen in cardiac transplant recipients. Am J Transplant. 2006;6:986–992.
    • (2006) Am J Transplant , vol.6 , pp. 986-992
    • Kuppahally, S.1    Al-Khaldi, A.2    Weisshaar, D.3
  • 87
    • 13144268553 scopus 로고    scopus 로고
    • Canadian society of transplantation consensus workshop on cytomegalovirus management in solid organ transplantation final report
    • J.K.Preiksaitis, D.C.Brennan, J.Fishman, et al. Canadian society of transplantation consensus workshop on cytomegalovirus management in solid organ transplantation final report. Am J Transplant. 2005;5:218–227.
    • (2005) Am J Transplant , vol.5 , pp. 218-227
    • Preiksaitis, J.K.1    Brennan, D.C.2    Fishman, J.3
  • 88
    • 33749337524 scopus 로고    scopus 로고
    • Antiviral drugs for cytomegalovirus in transplant recipients: advantages of preemptive therapy
    • N.Singh. Antiviral drugs for cytomegalovirus in transplant recipients: advantages of preemptive therapy. Rev Med Virol. 2006;16:281–287.
    • (2006) Rev Med Virol , vol.16 , pp. 281-287
    • Singh, N.1
  • 89
    • 0035062921 scopus 로고    scopus 로고
    • Prophylaxis for CMV should not now replace pre-emptive therapy in solid organ transplantation
    • V.C.Emery. Prophylaxis for CMV should not now replace pre-emptive therapy in solid organ transplantation. Rev Med Virol. 2001;11:83–86.
    • (2001) Rev Med Virol , vol.11 , pp. 83-86
    • Emery, V.C.1
  • 90
    • 33749363597 scopus 로고    scopus 로고
    • The case for cytomegalovirus prophylaxis in solid organ transplantation
    • D.R.Snydman. The case for cytomegalovirus prophylaxis in solid organ transplantation. Rev Med Virol. 2006;16:289–295.
    • (2006) Rev Med Virol , vol.16 , pp. 289-295
    • Snydman, D.R.1
  • 91
    • 33746895463 scopus 로고    scopus 로고
    • Prophylactic versus preemptive oral valganciclovir for the management of cytomegalovirus infection in adult renal transplant recipients
    • J.A.Khoury, G.A.Storch, D.L.Bohl, et al. Prophylactic versus preemptive oral valganciclovir for the management of cytomegalovirus infection in adult renal transplant recipients. Am J Transplant. 2006;6:2134–2143.
    • (2006) Am J Transplant , vol.6 , pp. 2134-2143
    • Khoury, J.A.1    Storch, G.A.2    Bohl, D.L.3
  • 92
    • 65449167596 scopus 로고    scopus 로고
    • Prophylaxis versus preemptive anti-cytomegalovirus approach for prevention of allograft vasculopathy in heart transplant recipients
    • L.Potena, F.Grigioni, G.Magnani, et al. Prophylaxis versus preemptive anti-cytomegalovirus approach for prevention of allograft vasculopathy in heart transplant recipients. J Heart Lung Transplant. 2009;28:461–467.
    • (2009) J Heart Lung Transplant , vol.28 , pp. 461-467
    • Potena, L.1    Grigioni, F.2    Magnani, G.3
  • 93
    • 84883453128 scopus 로고    scopus 로고
    • Impact of antiviral preventive strategies on the incidence and outcomes of cytomegalovirus disease in solid organ transplant recipients
    • O.Manuel, G.Kralidis, N.J.Mueller, et al. Impact of antiviral preventive strategies on the incidence and outcomes of cytomegalovirus disease in solid organ transplant recipients. Am J Transplant. 2013;13:2402–2410.• This study represents a snapshot of current practice for CMV prevention in the United States. The results support the concept that prophylaxis may exert a greater graft protection effect than preemptive strategy.
    • (2013) Am J Transplant , vol.13 , pp. 2402-2410
    • Manuel, O.1    Kralidis, G.2    Mueller, N.J.3
  • 94
    • 34347402281 scopus 로고    scopus 로고
    • Prophylaxis and treatment of cytomegalovirus disease in recipients of solid organ transplants: current approach and future challenges
    • Y.A.Puius, D.R.Snydman. Prophylaxis and treatment of cytomegalovirus disease in recipients of solid organ transplants: current approach and future challenges. Curr Opin Infect Dis. 2007;20:419–424.
    • (2007) Curr Opin Infect Dis , vol.20 , pp. 419-424
    • Puius, Y.A.1    Snydman, D.R.2
  • 95
    • 85028487304 scopus 로고    scopus 로고
    • Everolimus and valganciclovir prophylaxis: how to chase CMV but not the patient: insights from PROTECT randomized study
    • B.Perciaccante, G.Bianchi, L.Potena, et al. Everolimus and valganciclovir prophylaxis: how to chase CMV but not the patient: insights from PROTECT randomized study. J Heart Lung Transpl. 2015;34:S305.
    • (2015) J Heart Lung Transpl , vol.34 , pp. S305
    • Perciaccante, B.1    Bianchi, G.2    Potena, L.3
  • 96
    • 77950926374 scopus 로고    scopus 로고
    • International consensus guidelines on the management of cytomegalovirus in solid organ transplantation
    • C.N.Kotton, D.Kumar, A.M.Caliendo, et al. International consensus guidelines on the management of cytomegalovirus in solid organ transplantation. Transplantation. 2010;89:779–795.
    • (2010) Transplantation , vol.89 , pp. 779-795
    • Kotton, C.N.1    Kumar, D.2    Caliendo, A.M.3
  • 97
    • 33847363922 scopus 로고    scopus 로고
    • Evaluation of cytomegalovirus DNAaemia versus pp65-antigenaemia cutoff for guiding preemptive therapy in transplant recipients: a randomized study
    • G.Gerna, F.Baldanti, M.Torsellini, et al. Evaluation of cytomegalovirus DNAaemia versus pp65-antigenaemia cutoff for guiding preemptive therapy in transplant recipients: a randomized study. Antivir Ther. 2007;12:63–72.
    • (2007) Antivir Ther , vol.12 , pp. 63-72
    • Gerna, G.1    Baldanti, F.2    Torsellini, M.3
  • 98
    • 46149121948 scopus 로고    scopus 로고
    • Relationship of cytomegalovirus load assessed by real-time PCR to pp65 antigenemia in organ transplant recipients
    • S.K.Sanghavi, K.Abu-Elmagd, M.C.Keightley, et al. Relationship of cytomegalovirus load assessed by real-time PCR to pp65 antigenemia in organ transplant recipients. J Clin Virol. 2008;42:335–342.
    • (2008) J Clin Virol , vol.42 , pp. 335-342
    • Sanghavi, S.K.1    Abu-Elmagd, K.2    Keightley, M.C.3
  • 99
    • 84871516782 scopus 로고    scopus 로고
    • Determination, validation and standardization of a CMV DNA cut-off value in plasma for preemptive treatment of CMV infection in solid organ transplant recipients at lower risk for CMV infection
    • C.Martin-Gandul, P.Perez-Romero, M.Sanchez, et al. Determination, validation and standardization of a CMV DNA cut-off value in plasma for preemptive treatment of CMV infection in solid organ transplant recipients at lower risk for CMV infection. J Clin Virol. 2013;56:13–18.
    • (2013) J Clin Virol , vol.56 , pp. 13-18
    • Martin-Gandul, C.1    Perez-Romero, P.2    Sanchez, M.3
  • 100
    • 65249100197 scopus 로고    scopus 로고
    • Preemptive therapy for systemic and pulmonary human cytomegalovirus infection in lung transplant recipients
    • G.Gerna, D.Lilleri, V.Rognoni, et al. Preemptive therapy for systemic and pulmonary human cytomegalovirus infection in lung transplant recipients. Am J Transplant. 2009;9:1142–1150.
    • (2009) Am J Transplant , vol.9 , pp. 1142-1150
    • Gerna, G.1    Lilleri, D.2    Rognoni, V.3
  • 101
    • 0034631463 scopus 로고    scopus 로고
    • Application of viral-load kinetics to identify patients who develop cytomegalovirus disease after transplantation
    • V.C.Emery, C.A.Sabin, A.V.Cope, et al. Application of viral-load kinetics to identify patients who develop cytomegalovirus disease after transplantation. Lancet. 2000;355:2032–2036.
    • (2000) Lancet , vol.355 , pp. 2032-2036
    • Emery, V.C.1    Sabin, C.A.2    Cope, A.V.3
  • 102
    • 70349696561 scopus 로고    scopus 로고
    • Multicenter quality control study for human cytomegalovirus DNAemia quantification
    • D.Lilleri, T.Lazzarotto, V.Ghisetti, et al. Multicenter quality control study for human cytomegalovirus DNAemia quantification. New Microbiol. 2009;32:245–253.
    • (2009) New Microbiol , vol.32 , pp. 245-253
    • Lilleri, D.1    Lazzarotto, T.2    Ghisetti, V.3
  • 103
    • 58849125291 scopus 로고    scopus 로고
    • Interlaboratory comparison of cytomegalovirus viral load assays
    • X.L.Pang, J.D.Fox, J.M.Fenton, et al. Interlaboratory comparison of cytomegalovirus viral load assays. Am J Transplant. 2009;9:258–268.
    • (2009) Am J Transplant , vol.9 , pp. 258-268
    • Pang, X.L.1    Fox, J.D.2    Fenton, J.M.3
  • 104
    • 84941960285 scopus 로고    scopus 로고
    • Commutability of the first world health organization international standard for human cytomegalovirus
    • R.T.Hayden, J.Preiksaitis, Y.Tong, et al. Commutability of the first world health organization international standard for human cytomegalovirus. J Clin Microbiol. 2015;53:3325–3333.
    • (2015) J Clin Microbiol , vol.53 , pp. 3325-3333
    • Hayden, R.T.1    Preiksaitis, J.2    Tong, Y.3
  • 105
    • 33847023002 scopus 로고    scopus 로고
    • Relationship between cytomegalovirus DNA load in epithelial lining fluid and plasma of lung transplant recipients and analysis of coinfection with Epstein-Barr virus and human herpesvirus 6 in the lung compartment
    • C.C.Bauer, P.Jaksch, S.W.Aberle, et al. Relationship between cytomegalovirus DNA load in epithelial lining fluid and plasma of lung transplant recipients and analysis of coinfection with Epstein-Barr virus and human herpesvirus 6 in the lung compartment. J Clin Microbiol. 2007;45:324–328.
    • (2007) J Clin Microbiol , vol.45 , pp. 324-328
    • Bauer, C.C.1    Jaksch, P.2    Aberle, S.W.3
  • 106
    • 84883162770 scopus 로고    scopus 로고
    • Systemic and local human cytomegalovirus-specific T-cell response in lung transplant recipients
    • D.Lilleri, G.Gerna, F.Bruno, et al. Systemic and local human cytomegalovirus-specific T-cell response in lung transplant recipients. New Microbiol. 2013;36:267–277.• This study provides evidences that immune response against CMV may be exerted locally in the lung allograft, and not be detected in the bloodstream. The local response appears to be more protective than the systemic one.
    • (2013) New Microbiol , vol.36 , pp. 267-277
    • Lilleri, D.1    Gerna, G.2    Bruno, F.3
  • 107
    • 84879694363 scopus 로고    scopus 로고
    • Detection of human cytomegalovirus in transbronchial biopsies from lung transplant recipients
    • C.Costa, A.Curtoni, F.Sidoti, et al. Detection of human cytomegalovirus in transbronchial biopsies from lung transplant recipients. Arch Virol. 2013;158:1461–1465.
    • (2013) Arch Virol , vol.158 , pp. 1461-1465
    • Costa, C.1    Curtoni, A.2    Sidoti, F.3
  • 108
    • 84873097497 scopus 로고    scopus 로고
    • Late-onset cytomegalovirus (CMV) in lung transplant recipients: can CMV serostatus guide the duration of prophylaxis?
    • S.Ke, D.M.Lyu, T.J.Grazia, et al. Late-onset cytomegalovirus (CMV) in lung transplant recipients: can CMV serostatus guide the duration of prophylaxis? Am J Transplant. 2013;13:376–382.• Very large observational study supporting that in lung transplantation donor serology represents a risk factor for CMV disease also in seropositive recipients.
    • (2013) Am J Transplant , vol.13 , pp. 376-382
    • Ke, S.1    Lyu, D.M.2    Grazia, T.J.3
  • 109
    • 84872893258 scopus 로고    scopus 로고
    • The lack of cytomegalovirus-specific cellular immune response may contribute to the onset of organ infection and disease in lung transplant recipients
    • C.Costa, A.Saldan, F.Sinesi, et al. The lack of cytomegalovirus-specific cellular immune response may contribute to the onset of organ infection and disease in lung transplant recipients. Int J Immunopathol Pharmacol. 2012;25:1003–1009.• This study supports the use of elispot to identify lung recipients at highest risk for CMV disease.
    • (2012) Int J Immunopathol Pharmacol , vol.25 , pp. 1003-1009
    • Costa, C.1    Saldan, A.2    Sinesi, F.3
  • 110
    • 17344368192 scopus 로고    scopus 로고
    • Delayed acquisition of high-avidity anti-cytomegalovirus antibody is correlated with prolonged antigenemia in solid organ transplant recipients
    • Lazzarotto T, Varani S, Spezzacatena P, et al. Delayed acquisition of high-avidity anti-cytomegalovirus antibody is correlated with prolonged antigenemia in solid organ transplant recipients. J Infect Dis. 1998;178:1145–1149.
    • (1998) J Infect Dis , vol.178 , pp. 1145-1149
  • 111
    • 33749601263 scopus 로고    scopus 로고
    • T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease
    • W.Tu, L.Potena, P.Stepick-Biek, et al. T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease. Circulation. 2006;114:1608–1615.
    • (2006) Circulation , vol.114 , pp. 1608-1615
    • Tu, W.1    Potena, L.2    Stepick-Biek, P.3
  • 112
    • 84867429340 scopus 로고    scopus 로고
    • An analysis of regulatory T-cell and Th-17 cell dynamics during cytomegalovirus replication in solid organ transplant recipients
    • A.Egli, M.SilvaJr., D.O’Shea, et al. An analysis of regulatory T-cell and Th-17 cell dynamics during cytomegalovirus replication in solid organ transplant recipients. PLoS One. 2012;7:e43937.
    • (2012) PLoS One , vol.7 , pp. 43937
    • Egli, A.1    Silva, M.2    O’Shea, D.3
  • 113
    • 48349128233 scopus 로고    scopus 로고
    • Linking CMV serostatus to episodes of CMV reactivation following lung transplantation by measuring CMV-specific CD8+ T-cell immunity
    • G.P.Westall, N.A.Mifsud, T.Kotsimbos. Linking CMV serostatus to episodes of CMV reactivation following lung transplantation by measuring CMV-specific CD8+ T-cell immunity. Am J Transplant. 2008;8:1749–1754.
    • (2008) Am J Transplant , vol.8 , pp. 1749-1754
    • Westall, G.P.1    Mifsud, N.A.2    Kotsimbos, T.3
  • 114
    • 84874774789 scopus 로고    scopus 로고
    • Assessment of cytomegalovirus-specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients: a multicenter cohort study
    • O.Manuel, S.Husain, D.Kumar, et al. Assessment of cytomegalovirus-specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients: a multicenter cohort study. Clin Infect Dis. 2013;56:817–824.
    • (2013) Clin Infect Dis , vol.56 , pp. 817-824
    • Manuel, O.1    Husain, S.2    Kumar, D.3
  • 115
    • 84855848791 scopus 로고    scopus 로고
    • Clinical utility of cytomegalovirus cell-mediated immunity in transplant recipients with cytomegalovirus viremia
    • L.F.Lisboa, D.Kumar, L.E.Wilson, et al. Clinical utility of cytomegalovirus cell-mediated immunity in transplant recipients with cytomegalovirus viremia. Transplantation. 2012;93:195–200.
    • (2012) Transplantation , vol.93 , pp. 195-200
    • Lisboa, L.F.1    Kumar, D.2    Wilson, L.E.3
  • 116
    • 85028486876 scopus 로고    scopus 로고
    • Interim analysis: a study of quantiFERON-CMV-Directed CMV prophylaxis versus standard-of-care to reduce late cmv reactivation in patients undergoing lung transplantation
    • G.P.Westall, Y.Cristiano, A.Y.Peleg, et al. Interim analysis: a study of quantiFERON-CMV-Directed CMV prophylaxis versus standard-of-care to reduce late cmv reactivation in patients undergoing lung transplantation. J Heart Lung Transplant. 2016;35:S105.
    • J Heart Lung Transplant , vol.2016 , pp. S105
    • Westall, G.P.1    Cristiano, Y.2    Peleg, A.Y.3
  • 117
    • 84884408512 scopus 로고    scopus 로고
    • Tailored cytomegalovirus management in lung transplant recipient: a single-center experience
    • P.Solidoro, C.Costa, D.Libertucci, et al. Tailored cytomegalovirus management in lung transplant recipient: a single-center experience. Transplant Proc. 2013;45:2736–2740.
    • (2013) Transplant Proc , vol.45 , pp. 2736-2740
    • Solidoro, P.1    Costa, C.2    Libertucci, D.3
  • 118
    • 84876732286 scopus 로고    scopus 로고
    • Desirability and feasibility of a vaccine against cytomegalovirus
    • P.Griffiths, S.Plotkin, E.Mocarski, et al. Desirability and feasibility of a vaccine against cytomegalovirus. Vaccine. 2013;31(Suppl 2):B197–B203.
    • (2013) Vaccine , vol.31 , pp. B197-B203
    • Griffiths, P.1    Plotkin, S.2    Mocarski, E.3
  • 119
    • 79953743926 scopus 로고    scopus 로고
    • Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial
    • P.D.Griffiths, A.Stanton, E.McCarrell, et al. Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial. Lancet. 2011;377:1256–1263.
    • (2011) Lancet , vol.377 , pp. 1256-1263
    • Griffiths, P.D.1    Stanton, A.2    McCarrell, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.