Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS: The cytomegalovirus retreatment trial

Archives of Ophthalmology

Volumn 114, Issue 1, 1996, Pages 23-33

  Jabs, ^a  

^a SOCA Chairman's Office   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIDANOSINE; FOSCARNET SODIUM; GANCICLOVIR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; ZALCITABINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ANEMIA; ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; EYE PHOTOGRAPHY; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NEPHROTOXICITY; NEUTROPENIA; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RELAPSE; RETINITIS; THROMBOCYTOPENIA; TREATMENT OUTCOME; VISUAL ACUITY; VISUAL FIELD;

EID: 9044238842     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.1996.01100130021004     Document Type: Article

References (44)

1. Holland GN, Pepose JS, Pettit TH, et al. Acquired immune deficiency syndrome: ocular manifestations Ophthalmology. 1983;90:859-873.
2. Palestine AG, Rodrigues MM, Macher AM, et al. Ophthalmic involvement in acquired immunodeficiency syndrome. Ophthalmology. 1984;91:1092-1099.
3. Freeman WR, Lerner CW, Mines JA, et al A prospective study of the ophthalmologic findings in the acquired immune deficiency syndrome. Am J Ophthalmol. 1984;97:133-142.
4. Pepose JS, Holland GN, Nestor MS, et al. Acquired immune deficiency syndrome: pathogenic mechanisms of ocular disease. Ophthalmology. 1985;92: 472-484.
5. Jacobson MA, O'Donnell JJ, Porteous D, et al. Retinal and gastrointestinal disease due to cytomegalovirus in patients with the acquired immune deficiency syndrome: prevalence, natural history, and response to ganciclovir therapy. QJM 1988;67.473-486.
6. Jabs DA, Enger C, Bartlett JG. Cytomepalovirus retinitis and acquired immunodeficiency syndrome. Arch Ophthalmol. 1989;107:75-80.
7. Jabs DA, Green WR, Fox R, et al. Ocular manifestations of acquired immune deficiency syndrome. Ophthalmology. 1989,96 1092-1099.
8. Pertel P, Hirschtick R, Phair J, et at. Risk of developing cytomegalovirus retinitis in persons infected with the human immunodeficiency virus. J Acquir Immune Defic Syndr. 1992;5:1069-1074
9. Gallant JE, Moore RD, Richman DD, et al. Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine. J Infect Dis. 1992,166:1223-1227
10. Kuppermann BD, Petty JG, Richman DD, et al. Correlation between CD4+ counts and prevalence of cytomegalovirus retinitis and human immunodeficiency virus-related noninfectious retinal vasculopathy in patients with acquired immunodeficiency syndrome Am J Ophthalmol. 1993,115.575-582.
11. Hoover DR, Saah AJ, Bacellar H, et al. Clinical manifestations of AIDS in the era of Pneumocystis prophylaxis. N Engl J Med. 1993;329:1922-1926.
12. Holland GN, Buhles WC Jr, Mastre B, et al. A controlled retrospective study of ganciclovir treatment for cytomegalovirus retinopathy, use of a standardized system for the assessment of disease outcome. Arch Ophthalmol. 1989,107 1759-1766
13. Gross JG, Bozzette SA, Mathews WC, et al. Longitudinal study of cytomegalovirus retinitis in acquired immune deficiency syndrome. Ophthalmology. 1990; 97 681-686.
14. Palestine AG, Polis MA, De Smet MD, et al A randomized, controlled trial of foscarnet in the treatment of cytomegalovirus retinitis in patients with AIDS. Ann Intern Med. 1991;115.665-673
15. Spector SA, Weingeist T, Pollard RB, et al. A randomized, controlled study of intravenous ganciclovir therapy for cytomegalovirus peripheral retinitis in patients with AIDS J Infect Dis 1993;168:557-563.
16. Jacobson MA, Causey D, Polsky B, et al. A dose-ranging study of daily maintenance intravenous foscarnet therapy for cytomegalovirus retinitis in AIDS. J Infect Dis 1993;168:444-448
17. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group. Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis. N Engl J Med 1992;326:213-220.
18. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group. Foscarnet-Ganciclovir Cytomegalovirus Retinitis trial, 4. visual outcomes. Ophthalmology. 1994;101:1250-1261.
19. Centers for Disease Control. Revision of the CDC surveillance case definition for acquired immunodeficiency syndrome. MMWR Morb Mortal Wkly Rep 1987, 36(suppl) 1S.
20. Katlama C, Dohin E, Caumes E, et al Foscarnet induction therapy for cytomegalovirus retinitis in AIDS: comparison of twice-daily and three-times-daily regimens. J Acquir Immune Defic Syndr. 1992;5(suppl 1):S18-S24.
21. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group. Studies of ocular complications of AIDS Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial, 1. rationale, design, and methods. Control Clin Trials. 1992;13:22-39.
22. Cockcroft DW, Gault MH Prediction of creatinine clearance from serum creatinine Nephron 1976;16:31-41.
23. Grossberg HS, Bonnem EM. GM-CSF with ganciclovir for the treatment of CMV retinitis in AIDS. N Engl J Med. 1989;320:1560
24. Hardy WD Combination ganciclovir and recombinant human granulocyte-macrophage colony-stimulating factor in the treatment of cytomegalovirus retinitis in AIDS patients. J Acquir Immune Defic Syndr. 1991,4(suppl).S22-S28.
25. Karnofsky DA, Abelmann WH, Craver LF, Burchenal JH. The use of nitrogen mustards in the palliative treatment of carcinoma, with particular reference to bronchogenic carcinoma. Cancer. 1948;1:634-656.
26. Ferris FL III, Kassoff A, Bresnick GH, Bailey I. New visual acuity charts for clinical research. Am J Ophthalmol. 1982;94:91-96.
27. The Diabetic Retinopathy Study Research Group. Photocoagulation treatment of proliferative diabetic retinopathy the second report of Diabetic Retmopathy Study findings. Ophthalmology. 1978;85:82-106.
28. Azen SP, Irvine AR, Davis MD, et al. The validity and reliability of photographic documentation of proliferate vitreoretinopathy. Ophthalmology 1989,96:352-357.
29. Wu AW, Rubin HR, Mathews WC, et al A 30-item health status instrument for AIDS clinical trials, preliminary validation in persons with early HIV infection. Med Care 1991;29:786-798.
30. Altman DG. Practical Statistics for Medical Research. New York, NY: Chapman & Hall, 1991.
31. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
32. Brookmeyer R, Crowley J A confidence interval for the median survival time. Biometrics. 1982;38:29-41.
33. Lin DO, Wei LS. The robust inference for the Cox proportional hazards model. J Am Stat Assoc. 1989;84:1074-1077.
34. Breslow N. Test of hypotheses in an overdispersed Poisson regression and other quasi-likelihood models. J Am Stat Assoc. 1990;85:565-571.
35. Liang KY, Zeger SL. Longitudinal data analysis using generalized linear models. Biometrika 1986;73:13-22.
36. Freitas VR, Fraser-Smith EB, Matthew TR. Increased efficacy of ganciclovir in combination with foscarnet against cytomegalovirus and herpes simplex virus type 2 in vitro and in vivo. Antiviral Res. 1989;12.205-212.
37. Manischewitz JF, Quinnan GV Jr, Lane HC, Wittek AE. Synergistic effect of ganciclovir and foscarnet on cytomegalovirus replication in vitro. Antimicrob Agents Chemother. 1990,34:373-375.
38. Dieterich DT, Poles MA, Lew EA, et al Concurrent use of ganciclovir and foscarnet to treat cytomegalovirus infection in AIDS patients. J Infect Dis. 1993, 167 1184-1188
39. Kuppermann BD, Flores-Aguilar M, Quiceno JI, Rickman LS, Freeman WR Combination ganciclovir and foscarnet in the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome. Arch Ophthalmol. 1993;111:1359-1366.
40. Weinberg DV, Murhpy R, Naughton K. Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis Am J Ophthalmol. 1994:117:776-782.
41. Nelson MR, Barter G, Hawkins D, Gazzard BG. Simultaneous treatment of cytomegalovirus retinitis with ganciclovir and foscarnet. Lancet. 1991;338:250.
42. Jacobson MA, Drew WL, Feinberg J, et al. Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS. J Infect Dis. 1991; 163:1348-1351
43. Dunn JP, MacCumber MW, Forman MS, Charache P, Apuzzo L, Jabs DA. Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir. Am J Ophthalmol 1995;119:587-596.
44. Drew WL, Miner RC, Busch DF, et al. Prevalence of resistance in patients receiving ganciclovir for serious cytomegalovirus infection. J Infect Dis. 1991; 163:716-719.