메뉴 건너뛰기




Volumn 18, Issue 9, 2016, Pages

The Traveling Microbiome

Author keywords

Dysbiosis; Microbiome; Travelers diarrhea

Indexed keywords

PREBIOTIC AGENT; PROBIOTIC AGENT;

EID: 84979243074     PISSN: 15233847     EISSN: 15343146     Source Type: Journal    
DOI: 10.1007/s11908-016-0536-7     Document Type: Review
Times cited : (28)

References (109)
  • 1
    • 84979260330 scopus 로고    scopus 로고
    • Microbiome & Trave
    • Public Library of Medicine Collection, Microbiome & Travel, URL http://www.ncbi.nlm.nih.gov/sites/myncbi/1Zq3a6-m-qsQd/collections/49641581/public/. 2015.
    • (2015) Public Library of Medicine Collection
  • 2
    • 84923762812 scopus 로고    scopus 로고
    • A new initiative on precision medicine
    • COI: 1:CAS:528:DC%2BC2MXjvFGnsLY%3D, PID: 2563534
    • Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med. 2015;372(9):793–5. doi:10.1056/NEJMp1500523.
    • (2015) N Engl J Med , vol.372 , Issue.9 , pp. 793-795
    • Collins, F.S.1    Varmus, H.2
  • 3
    • 50249099816 scopus 로고    scopus 로고
    • Metabolic phenotyping in health and disease
    • COI: 1:CAS:528:DC%2BD1cXhtFCqs7jE, PID: 1877530
    • Holmes E, Wilson ID, Nicholson JK. Metabolic phenotyping in health and disease. Cell. 2008;134(5):714–7. doi:10.1016/j.cell.2008.08.026.
    • (2008) Cell , vol.134 , Issue.5 , pp. 714-717
    • Holmes, E.1    Wilson, I.D.2    Nicholson, J.K.3
  • 4
    • 84978852361 scopus 로고    scopus 로고
    • The human gut microbiome and its dysfunctions through the meta-omics prism
    • PID: 2694582
    • Mondot S, Lepage P. The human gut microbiome and its dysfunctions through the meta-omics prism. Ann N Y Acad Sci. 2016. doi:10.1111/nyas.13033.
    • (2016) Ann N Y Acad Sci
    • Mondot, S.1    Lepage, P.2
  • 5
    • 84901506886 scopus 로고    scopus 로고
    • Surface area of the digestive tract - revisited
    • PID: 2469428
    • Helander HF, Fandriks L. Surface area of the digestive tract - revisited. Scand J Gastroenterol. 2014;49(6):681–9. doi:10.3109/00365521.2014.898326.
    • (2014) Scand J Gastroenterol , vol.49 , Issue.6 , pp. 681-689
    • Helander, H.F.1    Fandriks, L.2
  • 6
    • 79960923900 scopus 로고    scopus 로고
    • Mucosal biofilm communities in the human intestinal tract
    • COI: 1:CAS:528:DC%2BC3MXht12isb%2FP, PID: 2180724
    • Macfarlane S, Bahrami B, Macfarlane GT. Mucosal biofilm communities in the human intestinal tract. Adv Appl Microbiol. 2011;75:111–43. doi:10.1016/B978-0-12-387046-9.00005-0.
    • (2011) Adv Appl Microbiol , vol.75 , pp. 111-143
    • Macfarlane, S.1    Bahrami, B.2    Macfarlane, G.T.3
  • 7
    • 84861980130 scopus 로고    scopus 로고
    • Interactions between the microbiota and the immune system
    • COI: 1:CAS:528:DC%2BC38XnvFektL8%3D, PID: 2267433
    • Hooper LV, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science. 2012;336(6086):1268–73. doi:10.1126/science.1223490.
    • (2012) Science , vol.336 , Issue.6086 , pp. 1268-1273
    • Hooper, L.V.1    Littman, D.R.2    Macpherson, A.J.3
  • 8
    • 0001354030 scopus 로고
    • Enhanced susceptibility to Salmonella infection in streptomycin-treated mice
    • COI: 1:STN:280:DyaF387mtVamug%3D%3D, PID: 1396848
    • Bohnhoff M, Miller CP. Enhanced susceptibility to Salmonella infection in streptomycin-treated mice. J Infect Dis. 1962;111:117–27.
    • (1962) J Infect Dis , vol.111 , pp. 117-127
    • Bohnhoff, M.1    Miller, C.P.2
  • 9
    • 84879343905 scopus 로고    scopus 로고
    • Control of pathogens and pathobionts by the gut microbiota
    • COI: 1:CAS:528:DC%2BC3sXpsFKrsLY%3D, PID: 2377879
    • Kamada N, Chen GY, Inohara N, Nunez G. Control of pathogens and pathobionts by the gut microbiota. Nat Immunol. 2013;14(7):685–90. doi:10.1038/ni.2608.
    • (2013) Nat Immunol , vol.14 , Issue.7 , pp. 685-690
    • Kamada, N.1    Chen, G.Y.2    Inohara, N.3    Nunez, G.4
  • 10
    • 84913557714 scopus 로고    scopus 로고
    • The rest of the story: the microbiome and gastrointestinal infections
    • COI: 1:CAS:528:DC%2BC2cXitVeisLvE, PID: 25461582, A good review of susceptibility to enteric infection based on the gut microbiome’s varied colonizatio
    • Leslie JL, Young VB. The rest of the story: the microbiome and gastrointestinal infections. Curr Opin Microbiol. 2015;23:121–5. doi:10.1016/j.mib.2014.11.010. A good review of susceptibility to enteric infection based on the gut microbiome’s varied colonization.
    • (2015) Curr Opin Microbiol , vol.23 , pp. 121-125
    • Leslie, J.L.1    Young, V.B.2
  • 11
    • 84867615958 scopus 로고    scopus 로고
    • Suppression of Clostridium difficile in the gastrointestinal tracts of germfree mice inoculated with a murine isolate from the family Lachnospiraceae
    • COI: 1:CAS:528:DC%2BC38XhsFKmtrfF, PID: 2289099
    • Reeves AE, Koenigsknecht MJ, Bergin IL, Young VB. Suppression of Clostridium difficile in the gastrointestinal tracts of germfree mice inoculated with a murine isolate from the family Lachnospiraceae. Infect Immun. 2012;80(11):3786–94. doi:10.1128/iai.00647-12.
    • (2012) Infect Immun , vol.80 , Issue.11 , pp. 3786-3794
    • Reeves, A.E.1    Koenigsknecht, M.J.2    Bergin, I.L.3    Young, V.B.4
  • 12
    • 84898771460 scopus 로고    scopus 로고
    • Role of the intestinal microbiota in resistance to colonization by Clostridium difficile
    • COI: 1:CAS:528:DC%2BC2cXmslWqsb8%3D, PID: 2450313
    • Britton RA, Young VB. Role of the intestinal microbiota in resistance to colonization by Clostridium difficile. Gastroenterology. 2014;146(6):1547–53. doi:10.1053/j.gastro.2014.01.059.
    • (2014) Gastroenterology , vol.146 , Issue.6 , pp. 1547-1553
    • Britton, R.A.1    Young, V.B.2
  • 13
    • 84920621547 scopus 로고    scopus 로고
    • Gut microbiota-produced succinate promotes C. difficile infection after antibiotic treatment or motility disturbance
    • COI: 1:CAS:528:DC%2BC2cXhvFOgsb%2FO, PID: 2549834
    • Ferreyra JA, Wu KJ, Hryckowian AJ, Bouley DM, Weimer BC, Sonnenburg JL. Gut microbiota-produced succinate promotes C. difficile infection after antibiotic treatment or motility disturbance. Cell Host Microbe. 2014;16(6):770–7. doi:10.1016/j.chom.2014.11.003.
    • (2014) Cell Host Microbe , vol.16 , Issue.6 , pp. 770-777
    • Ferreyra, J.A.1    Wu, K.J.2    Hryckowian, A.J.3    Bouley, D.M.4    Weimer, B.C.5    Sonnenburg, J.L.6
  • 14
    • 84905402416 scopus 로고    scopus 로고
    • Structural and functional changes in the gut microbiota associated to Clostridium difficile infection
    • PID: 2530951
    • Perez-Cobas AE, Artacho A, Ott SJ, Moya A, Gosalbes MJ, Latorre A. Structural and functional changes in the gut microbiota associated to Clostridium difficile infection. Front Microbiol. 2014;5:335. doi:10.3389/fmicb.2014.00335.
    • (2014) Front Microbiol , vol.5 , pp. 335
    • Perez-Cobas, A.E.1    Artacho, A.2    Ott, S.J.3    Moya, A.4    Gosalbes, M.J.5    Latorre, A.6
  • 15
    • 84925500413 scopus 로고    scopus 로고
    • Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
    • COI: 1:CAS:528:DC%2BC2cXhvVemtrvE, PID: 2533787
    • Buffie CG, Bucci V, Stein RR, McKenney PT, Ling L, Gobourne A, et al. Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile. Nature. 2015;517(7533):205–8. doi:10.1038/nature13828.
    • (2015) Nature , vol.517 , Issue.7533 , pp. 205-208
    • Buffie, C.G.1    Bucci, V.2    Stein, R.R.3    McKenney, P.T.4    Ling, L.5    Gobourne, A.6
  • 16
    • 84929940545 scopus 로고    scopus 로고
    • Importation and domestic transmission of Shigella sonnei resistant to ciprofloxacin—United States, May 2014-February 2015
    • PID: 2583724
    • Bowen A, Hurd J, Hoover C, Khachadourian Y, Traphagen E, Harvey E, et al. Importation and domestic transmission of Shigella sonnei resistant to ciprofloxacin—United States, May 2014-February 2015. MMWR Morb Mortal Wkly Rep. 2015;64(12):318–20.
    • (2015) MMWR Morb Mortal Wkly Rep , vol.64 , Issue.12 , pp. 318-320
    • Bowen, A.1    Hurd, J.2    Hoover, C.3    Khachadourian, Y.4    Traphagen, E.5    Harvey, E.6
  • 17
    • 0035126317 scopus 로고    scopus 로고
    • Downregulation of bactericidal peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulator
    • COI: 1:CAS:528:DC%2BD3MXhtVyltLs%3D, PID: 1117584
    • Islam D, Bandholtz L, Nilsson J, Wigzell H, Christensson B, Agerberth B, et al. Downregulation of bactericidal peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulator. Nat Med. 2001;7(2):180–5. doi:10.1038/84627.
    • (2001) Nat Med , vol.7 , Issue.2 , pp. 180-185
    • Islam, D.1    Bandholtz, L.2    Nilsson, J.3    Wigzell, H.4    Christensson, B.5    Agerberth, B.6
  • 18
    • 0033021978 scopus 로고    scopus 로고
    • Short-chain fatty acids improve clinical, pathologic, and microbiologic features of experimental shigellosis
    • COI: 1:CAS:528:DyaK1MXhtV2jtr0%3D, PID: 987802
    • Rabbani GH, Albert MJ, Hamidur Rahman AS, Moyenul Isalm M, Nasirul Islam KM, Alam K. Short-chain fatty acids improve clinical, pathologic, and microbiologic features of experimental shigellosis. J Infect Dis. 1999;179(2):390–7. doi:10.1086/314584.
    • (1999) J Infect Dis , vol.179 , Issue.2 , pp. 390-397
    • Rabbani, G.H.1    Albert, M.J.2    Hamidur Rahman, A.S.3    Moyenul Isalm, M.4    Nasirul Islam, K.M.5    Alam, K.6
  • 19
    • 84883139076 scopus 로고    scopus 로고
    • The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
    • den Besten G, van Eunen K, Groen AK, Venema K, Reijngoud DJ, Bakker BM. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res. 2013;54(9):2325–40. doi:10.1194/jlr.R036012.
    • (2013) J Lipid Res , vol.54 , Issue.9 , pp. 2325-2340
    • den Besten, G.1    van Eunen, K.2    Groen, A.K.3    Venema, K.4    Reijngoud, D.J.5    Bakker, B.M.6
  • 20
    • 33745122487 scopus 로고    scopus 로고
    • Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic
    • COI: 1:CAS:528:DC%2BD28XmsVWjsbY%3D, PID: 16740661, In this landmark paper, the Shigella-mediated downregulation of the host endogenous antibacterial peptide cathelicidin CAP-18 was shown to be reversed by short chain fatty acids, in this case oral butyrate, resulting in disease amelioratio
    • Raqib R, Sarker P, Bergman P, Ara G, Lindh M, Sack DA, et al. Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic. Proc Natl Acad Sci U S A. 2006;103(24):9178–83. doi:10.1073/pnas.0602888103. In this landmark paper, the Shigella-mediated downregulation of the host endogenous antibacterial peptide cathelicidin CAP-18 was shown to be reversed by short chain fatty acids, in this case oral butyrate, resulting in disease amelioration.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.24 , pp. 9178-9183
    • Raqib, R.1    Sarker, P.2    Bergman, P.3    Ara, G.4    Lindh, M.5    Sack, D.A.6
  • 21
    • 67649519024 scopus 로고    scopus 로고
    • Green banana reduces clinical severity of childhood shigellosis: a double-blind, randomized, controlled clinical trial
    • PID: 19319017, The authors institute human field trials using foods which are substrates for the production of butyrate by intestinal bacteria, demonstrating a significant reduction in disease outcome among children with severe shigellosi
    • Rabbani GH, Ahmed S, Hossain I, Islam R, Marni F, Akhtar M, et al. Green banana reduces clinical severity of childhood shigellosis: a double-blind, randomized, controlled clinical trial. Pediatr Infect Dis J. 2009;28(5):420–5. doi:10.1097/INF.0b013e31819510b5. The authors institute human field trials using foods which are substrates for the production of butyrate by intestinal bacteria, demonstrating a significant reduction in disease outcome among children with severe shigellosis.
    • (2009) Pediatr Infect Dis J , vol.28 , Issue.5 , pp. 420-425
    • Rabbani, G.H.1    Ahmed, S.2    Hossain, I.3    Islam, R.4    Marni, F.5    Akhtar, M.6
  • 22
    • 84860650355 scopus 로고    scopus 로고
    • Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial
    • COI: 1:CAS:528:DC%2BC38Xhs12qsLrK, PID: 2257473
    • Raqib R, Sarker P, Mily A, Alam NH, Arifuzzaman AS, Rekha RS, et al. Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial. BMC Infect Dis. 2012;12:111. doi:10.1186/1471-2334-12-111.
    • (2012) BMC Infect Dis , vol.12 , pp. 111
    • Raqib, R.1    Sarker, P.2    Mily, A.3    Alam, N.H.4    Arifuzzaman, A.S.5    Rekha, R.S.6
  • 23
    • 84878715402 scopus 로고    scopus 로고
    • Dietary choice affects Shiga toxin-producing Escherichia coli (STEC) O157:H7 colonization and disease
    • COI: 1:CAS:528:DC%2BC3sXhtFGkt7rN, PID: 2369060
    • Zumbrun SD, Melton-Celsa AR, Smith MA, Gilbreath JJ, Merrell DS, O’Brien AD. Dietary choice affects Shiga toxin-producing Escherichia coli (STEC) O157:H7 colonization and disease. Proc Natl Acad Sci U S A. 2013;110(23):E2126–33. doi:10.1073/pnas.1222014110.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.23 , pp. E2126-E2133
    • Zumbrun, S.D.1    Melton-Celsa, A.R.2    Smith, M.A.3    Gilbreath, J.J.4    Merrell, D.S.5    O’Brien, A.D.6
  • 24
    • 84894055913 scopus 로고    scopus 로고
    • The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria
    • COI: 1:CAS:528:DC%2BC2cXitVentLo%3D, PID: 24508234, The authors present a series of studies showing salmonella interact with natigen presenting cells of the gut to stimulate host immune responses promoting production of antimicrobialmolecules. This is significant in that it demonstrates bacterial manipulation of host immune response anti-commensa
    • Behnsen J, Jellbauer S, Wong CP, Edwards RA, George MD, Ouyang W, et al. The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria. Immunity. 2014;40(2):262–73. doi:10.1016/j.immuni.2014.01.003. The authors present a series of studies showing salmonella interact with natigen presenting cells of the gut to stimulate host immune responses promoting production of antimicrobialmolecules. This is significant in that it demonstrates bacterial manipulation of host immune response anti-commensal.
    • (2014) Immunity , vol.40 , Issue.2 , pp. 262-273
    • Behnsen, J.1    Jellbauer, S.2    Wong, C.P.3    Edwards, R.A.4    George, M.D.5    Ouyang, W.6
  • 25
    • 84894047387 scopus 로고    scopus 로고
    • The battle in the gut
    • COI: 1:CAS:528:DC%2BC2cXivFCis7s%3D, PID: 2456019
    • Monack DM. The battle in the gut. Immunity. 2014;40(2):173–5. doi:10.1016/j.immuni.2014.01.007.
    • (2014) Immunity , vol.40 , Issue.2 , pp. 173-175
    • Monack, D.M.1
  • 26
    • 84880417771 scopus 로고    scopus 로고
    • Probiotic bacteria reduce salmonella typhimurium intestinal colonization by competing for iron
    • COI: 1:CAS:528:DC%2BC3sXhtFaksbvO, PID: 2387031
    • Deriu E, Liu JZ, Pezeshki M, Edwards RA, Ochoa RJ, Contreras H, et al. Probiotic bacteria reduce salmonella typhimurium intestinal colonization by competing for iron. Cell Host Microbe. 2013;14(1):26–37. doi:10.1016/j.chom.2013.06.007.
    • (2013) Cell Host Microbe , vol.14 , Issue.1 , pp. 26-37
    • Deriu, E.1    Liu, J.Z.2    Pezeshki, M.3    Edwards, R.A.4    Ochoa, R.J.5    Contreras, H.6
  • 27
    • 46249110382 scopus 로고    scopus 로고
    • Probiotic Escherichia coli Nissle 1917 versus placebo for treating diarrhea of greater than 4 days duration in infants and toddlers
    • PID: 1846973
    • Henker J, Laass MW, Blokhin BM, Maydannik VG, Bolbot YK, Elze M, et al. Probiotic Escherichia coli Nissle 1917 versus placebo for treating diarrhea of greater than 4 days duration in infants and toddlers. Pediatr Infect Dis J. 2008;27(6):494–9. doi:10.1097/INF.0b013e318169034c.
    • (2008) Pediatr Infect Dis J , vol.27 , Issue.6 , pp. 494-499
    • Henker, J.1    Laass, M.W.2    Blokhin, B.M.3    Maydannik, V.G.4    Bolbot, Y.K.5    Elze, M.6
  • 28
    • 84959553385 scopus 로고    scopus 로고
    • Composition of human faecal microbiota in resistance to Campylobacter infection
    • A demonstration that travlers to high risk destinations for enteric infection are more susceptible to infection with Camplyobacter if their pre-travel microbiome demonstrates lower bacterial specie
    • Kampmann C, Dicksved J, Engstrand L, Rautelin H. Composition of human faecal microbiota in resistance to Campylobacter infection. Clin Microbiol Infect. 2016;22(1):61.e1–8. doi:10.1016/j.cmi.2015.09.004. A demonstration that travlers to high risk destinations for enteric infection are more susceptible to infection with Camplyobacter if their pre-travel microbiome demonstrates lower bacterial species.
    • (2016) Clin Microbiol Infect , vol.22 , Issue.1 , pp. 8-61
    • Kampmann, C.1    Dicksved, J.2    Engstrand, L.3    Rautelin, H.4
  • 29
    • 84863700148 scopus 로고    scopus 로고
    • Campylobacter jejuni induces acute enterocolitis in gnotobiotic IL-10−/− mice via Toll-like-receptor-2 and −4 signaling
    • COI: 1:CAS:528:DC%2BC38XhtVGmtrrP, PID: 2280825
    • Haag LM, Fischer A, Otto B, Plickert R, Kuhl AA, Gobel UB, et al. Campylobacter jejuni induces acute enterocolitis in gnotobiotic IL-10−/− mice via Toll-like-receptor-2 and −4 signaling. PLoS One. 2012;7(7), e40761. doi:10.1371/journal.pone.0040761.
    • (2012) PLoS One , vol.7 , Issue.7
    • Haag, L.M.1    Fischer, A.2    Otto, B.3    Plickert, R.4    Kuhl, A.A.5    Gobel, U.B.6
  • 30
    • 84928170245 scopus 로고    scopus 로고
    • Characterization of the human gut microbiome during travelers’ diarrhea
    • PID: 25695334, A well-designed study comparing gut microbiota of individuals with TD associated with ETEC, norovirus, mixed pathogens, TD with no pathogen identified to healthy travelers demostrating a dysbiotic profile in all travelers regardless of the development of T
    • Youmans BP, Ajami NJ, Jiang ZD, Campbell F, Wadsworth WD, Petrosino JF, et al. Characterization of the human gut microbiome during travelers’ diarrhea. Gut Microbes. 2015;6(2):110–9. doi:10.1080/19490976.2015.1019693. A well-designed study comparing gut microbiota of individuals with TD associated with ETEC, norovirus, mixed pathogens, TD with no pathogen identified to healthy travelers demostrating a dysbiotic profile in all travelers regardless of the development of TD.
    • (2015) Gut Microbes , vol.6 , Issue.2 , pp. 110-119
    • Youmans, B.P.1    Ajami, N.J.2    Jiang, Z.D.3    Campbell, F.4    Wadsworth, W.D.5    Petrosino, J.F.6
  • 31
    • 84908432766 scopus 로고    scopus 로고
    • Susceptibility to Campylobacter infection is associated with the species composition of the human fecal microbiota
    • COI: 1:CAS:528:DC%2BC2MXhslKit7o%3D, PID: 2522746
    • Dicksved J, Ellstrom P, Engstrand L, Rautelin H. Susceptibility to Campylobacter infection is associated with the species composition of the human fecal microbiota. mBio. 2014;5(5):e01212–4. doi:10.1128/mBio.01212-14.
    • (2014) mBio , vol.5 , Issue.5 , pp. e01212-e1214
    • Dicksved, J.1    Ellstrom, P.2    Engstrand, L.3    Rautelin, H.4
  • 32
    • 84868155170 scopus 로고    scopus 로고
    • Disruption of the human gut microbiota following Norovirus infection
    • COI: 1:CAS:528:DC%2BC38Xhs12qs7rM, PID: 23118957, Although not in a traveler setting, this study of acute norovirus infection showed a significant change in diversity characterized by increased Proteobacteriacia
    • Nelson AM, Walk ST, Taube S, Taniuchi M, Houpt ER, Wobus CE, et al. Disruption of the human gut microbiota following Norovirus infection. PLoS One. 2012;7(10):e48224. doi:10.1371/journal.pone.0048224. Although not in a traveler setting, this study of acute norovirus infection showed a significant change in diversity characterized by increased Proteobacteriaciae.
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e48224
    • Nelson, A.M.1    Walk, S.T.2    Taube, S.3    Taniuchi, M.4    Houpt, E.R.5    Wobus, C.E.6
  • 33
    • 84979212748 scopus 로고    scopus 로고
    • , search terms “Travel*” and “ESBL”, can be retrieved at
    • Public Library of Medicine Collection, search terms “Travel*” and “ESBL”, can be retrieved at http://www.ncbi.nlm.nih.gov/sites/myncbi/1Zq3a6-m-qsQd/collections/49647045/public/.
    • Public Library of Medicine Collection
  • 34
    • 84983552275 scopus 로고    scopus 로고
    • Hassing RJ, Alsma J, Arcilla MS, van Genderen PJ, Stricker BH, Verbon A. . Euro Surveill: Bull Euro Mal Transmissibles = Euro Commun Dis Bull. 2015;20(47). . Most up-to-date qualitative review of observational studies across multiple traveler populatons. Major findings are that travel particularly to Asia, and among those who developed TD and/or take antibiotics while traveling, consistently demonstrate the increased risk of acquiring ESBL bacteri
    • Hassing RJ, Alsma J, Arcilla MS, van Genderen PJ, Stricker BH, Verbon A. International travel and acquisition of multidrug-resistant Enterobacteriaceae: a systematic review. Euro Surveill: Bull Euro Mal Transmissibles = Euro Commun Dis Bull. 2015;20(47). doi:10.2807/1560-7917.ES.2015.20.47.30074. Most up-to-date qualitative review of observational studies across multiple traveler populatons. Major findings are that travel particularly to Asia, and among those who developed TD and/or take antibiotics while traveling, consistently demonstrate the increased risk of acquiring ESBL bacteria
    • International travel and acquisition of multidrug-resistant Enterobacteriaceae: a systematic review
  • 35
    • 85047285319 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamase-producing enterobacteriaceae among travelers from the Netherlands
    • PID: 2388597
    • Paltansing S, Vlot JA, Kraakman ME, Mesman R, Bruijning ML, Bernards AT, et al. Extended-spectrum beta-lactamase-producing enterobacteriaceae among travelers from the Netherlands. Emerg Infect Dis. 2013;19(8):1206–13. doi:10.3201/eid.1908.130257.
    • (2013) Emerg Infect Dis , vol.19 , Issue.8 , pp. 1206-1213
    • Paltansing, S.1    Vlot, J.A.2    Kraakman, M.E.3    Mesman, R.4    Bruijning, M.L.5    Bernards, A.T.6
  • 36
    • 77956102466 scopus 로고    scopus 로고
    • Foreign travel is a major risk factor for colonization with Escherichia coli producing CTX-M-type extended-spectrum beta-lactamases: a prospective study with Swedish volunteers
    • PID: 2054778
    • Tangden T, Cars O, Melhus A, Lowdin E. Foreign travel is a major risk factor for colonization with Escherichia coli producing CTX-M-type extended-spectrum beta-lactamases: a prospective study with Swedish volunteers. Antimicrob Agents Chemother. 2010;54(9):3564–8. doi:10.1128/AAC.00220-10.
    • (2010) Antimicrob Agents Chemother , vol.54 , Issue.9 , pp. 3564-3568
    • Tangden, T.1    Cars, O.2    Melhus, A.3    Lowdin, E.4
  • 37
    • 84977814242 scopus 로고    scopus 로고
    • Colonization with extended-spectrum beta-lactamase-producing and carbapenemase-producing Enterobacteriaceae in international travelers returning to Germany
    • PID: 2554726
    • Lubbert C, Straube L, Stein C, Makarewicz O, Schubert S, Mossner J, et al. Colonization with extended-spectrum beta-lactamase-producing and carbapenemase-producing Enterobacteriaceae in international travelers returning to Germany. Int J Med Microbiol: IJMM. 2015;305(1):148–56. doi:10.1016/j.ijmm.2014.12.001.
    • (2015) Int J Med Microbiol: IJMM , vol.305 , Issue.1 , pp. 148-156
    • Lubbert, C.1    Straube, L.2    Stein, C.3    Makarewicz, O.4    Schubert, S.5    Mossner, J.6
  • 38
    • 78651342861 scopus 로고    scopus 로고
    • Colonisation with Escherichia coli resistant to “critically important” antibiotics: a high risk for international travellers
    • COI: 1:STN:280:DC%2BC3M%2FgsFyhug%3D%3
    • Kennedy K, Collignon P. Colonisation with Escherichia coli resistant to “critically important” antibiotics: a high risk for international travellers. Euro J Clin Microbiol Infect Dis: Off Publ Euro Soc Clin Microbiol. 2010;29(12):1501–6. doi:10.1007/s10096-010-1031-y.
    • (2010) Euro J Clin Microbiol Infect Dis: Off Publ Euro Soc Clin Microbiol , vol.29 , Issue.12 , pp. 1501-1506
    • Kennedy, K.1    Collignon, P.2
  • 39
    • 84938596911 scopus 로고    scopus 로고
    • High rate of acquisition but short duration of carriage of multidrug-resistant enterobacteriaceae after travel to the tropics
    • PID: 2590436
    • Ruppe E, Armand-Lefevre L, Estellat C, Consigny PH, El Mniai A, Boussadia Y, et al. High rate of acquisition but short duration of carriage of multidrug-resistant enterobacteriaceae after travel to the tropics. Clin Infect Dis. 2015;61(4):593–600. doi:10.1093/cid/civ333.
    • (2015) Clin Infect Dis , vol.61 , Issue.4 , pp. 593-600
    • Ruppe, E.1    Armand-Lefevre, L.2    Estellat, C.3    Consigny, P.H.4    El Mniai, A.5    Boussadia, Y.6
  • 40
    • 77954739709 scopus 로고    scopus 로고
    • Emergence and dissemination of extended-spectrum beta-lactamase-producing Escherichia coli in the community: lessons from the study of a remote and controlled population
    • PID: 2061792
    • Woerther PL, Angebault C, Lescat M, Ruppe E, Skurnik D, Mniai AE, et al. Emergence and dissemination of extended-spectrum beta-lactamase-producing Escherichia coli in the community: lessons from the study of a remote and controlled population. J Infect Dis. 2010;202(4):515–23. doi:10.1086/654883.
    • (2010) J Infect Dis , vol.202 , Issue.4 , pp. 515-523
    • Woerther, P.L.1    Angebault, C.2    Lescat, M.3    Ruppe, E.4    Skurnik, D.5    Mniai, A.E.6
  • 41
    • 84964342444 scopus 로고    scopus 로고
    • Prevalence and risk factors for carriage of ESBL-producing Enterobacteriaceae in Amsterdam
    • COI: 1:STN:280:DC%2BC28rpt1Wmsw%3D%3D, PID: 26755493, This very recent study from the Netherlands demonstrates the risk of acquirng ESBL in travel is not limited to travel to exotic destination
    • Reuland EA, Al Naiemi N, Kaiser AM, Heck M, Kluytmans JA, Savelkoul PH, et al. Prevalence and risk factors for carriage of ESBL-producing Enterobacteriaceae in Amsterdam. J Antimicrob Chemother. 2016;71(4):1076–82. doi:10.1093/jac/dkv441. This very recent study from the Netherlands demonstrates the risk of acquirng ESBL in travel is not limited to travel to exotic destinations.
    • (2016) J Antimicrob Chemother , vol.71 , Issue.4 , pp. 1076-1082
    • Reuland, E.A.1    Al Naiemi, N.2    Kaiser, A.M.3    Heck, M.4    Kluytmans, J.A.5    Savelkoul, P.H.6
  • 42
    • 84979254658 scopus 로고    scopus 로고
    • Proceedings of the International Society of Travel Medicine Foundation Travelers’ Diarrhea Summit, J Travel Me
    • Riddle MS, DuPont HL, Ericsson CD, Connor BA. Proceedings of the International Society of Travel Medicine Foundation Travelers’ Diarrhea Summit. J Travel Med. 2016.
    • (2016) Connor BA
    • Riddle, M.S.1    DuPont, H.L.2    Ericsson, C.D.3
  • 43
    • 84869213296 scopus 로고    scopus 로고
    • Multidrug-resistant bacteria in travellers hospitalized abroad: prevalence, characteristics, and influence on clinical outcome
    • COI: 1:STN:280:DC%2BC3s%2FosF2kug%3D%3D, PID: 2310324
    • Nemeth J, Ledergerber B, Preiswerk B, Nobile A, Karrer S, Ruef C, et al. Multidrug-resistant bacteria in travellers hospitalized abroad: prevalence, characteristics, and influence on clinical outcome. J Hosp Infect. 2012;82(4):254–9. doi:10.1016/j.jhin.2012.08.017.
    • (2012) J Hosp Infect , vol.82 , Issue.4 , pp. 254-259
    • Nemeth, J.1    Ledergerber, B.2    Preiswerk, B.3    Nobile, A.4    Karrer, S.5    Ruef, C.6
  • 44
    • 84941191772 scopus 로고    scopus 로고
    • Risk factors for colonization with multidrug-resistant bacteria among patients admitted to the intensive care unit after returning from abroad
    • PID: 2608107
    • Angue M, Allou N, Belmonte O, Lefort Y, Lugagne N, Vandroux D, et al. Risk factors for colonization with multidrug-resistant bacteria among patients admitted to the intensive care unit after returning from abroad. J Travel Med. 2015;22(5):300–5. doi:10.1111/jtm.12220.
    • (2015) J Travel Med , vol.22 , Issue.5 , pp. 300-305
    • Angue, M.1    Allou, N.2    Belmonte, O.3    Lefort, Y.4    Lugagne, N.5    Vandroux, D.6
  • 45
    • 84941184830 scopus 로고    scopus 로고
    • High rate of multidrug-resistant gram-negative bacilli carriage and infection in hospitalized returning travelers: a cross-sectional cohort study
    • PID: 2599783
    • Epelboin L, Robert J, Tsyrina-Kouyoumdjian E, Laouira S, Meyssonnier V, Caumes E. High rate of multidrug-resistant gram-negative bacilli carriage and infection in hospitalized returning travelers: a cross-sectional cohort study. J Travel Med. 2015;22(5):292–9. doi:10.1111/jtm.12211.
    • (2015) J Travel Med , vol.22 , Issue.5 , pp. 292-299
    • Epelboin, L.1    Robert, J.2    Tsyrina-Kouyoumdjian, E.3    Laouira, S.4    Meyssonnier, V.5    Caumes, E.6
  • 46
    • 84856753656 scopus 로고    scopus 로고
    • Import and spread of Panton-valentine leukocidin-positive staphylococcus aureus through nasal carriage and skin infections in travelers returning from the tropics and subtropics
    • PID: 2210408
    • Zanger P, Nurjadi D, Schleucher R, Scherbaum H, Wolz C, Kremsner PG, et al. Import and spread of Panton-valentine leukocidin-positive staphylococcus aureus through nasal carriage and skin infections in travelers returning from the tropics and subtropics. Clin Infect Dis. 2012;54(4):483–92. doi:10.1093/cid/cir822.
    • (2012) Clin Infect Dis , vol.54 , Issue.4 , pp. 483-492
    • Zanger, P.1    Nurjadi, D.2    Schleucher, R.3    Scherbaum, H.4    Wolz, C.5    Kremsner, P.G.6
  • 47
    • 84905988318 scopus 로고    scopus 로고
    • Emergence of trimethoprim resistance gene dfrG in Staphylococcus aureus causing human infection and colonization in sub-Saharan Africa and its import to Europe
    • COI: 1:CAS:528:DC%2BC2MXis12qsLg%3D, PID: 2485512
    • Nurjadi D, Olalekan AO, Layer F, Shittu AO, Alabi A, Ghebremedhin B, et al. Emergence of trimethoprim resistance gene dfrG in Staphylococcus aureus causing human infection and colonization in sub-Saharan Africa and its import to Europe. J Antimicrob Chemother. 2014;69(9):2361–8. doi:10.1093/jac/dku174.
    • (2014) J Antimicrob Chemother , vol.69 , Issue.9 , pp. 2361-2368
    • Nurjadi, D.1    Olalekan, A.O.2    Layer, F.3    Shittu, A.O.4    Alabi, A.5    Ghebremedhin, B.6
  • 48
    • 84927798498 scopus 로고    scopus 로고
    • Knowledge and understanding of antibiotic resistance and the risk of becoming a carrier when travelling abroad: a qualitative study of Swedish travellers
    • COI: 1:STN:280:DC%2BC2MrosVWmsQ%3D%3
    • Wiklund S, Fagerberg I, Ortqvist A, Vading M, Giske CG, Broliden K, et al. Knowledge and understanding of antibiotic resistance and the risk of becoming a carrier when travelling abroad: a qualitative study of Swedish travellers. Scand J Publ Health. 2015;43(3):302–8. doi:10.1177/1403494815571788.
    • (2015) Scand J Publ Health , vol.43 , Issue.3 , pp. 302-308
    • Wiklund, S.1    Fagerberg, I.2    Ortqvist, A.3    Vading, M.4    Giske, C.G.5    Broliden, K.6
  • 49
    • 84883456874 scopus 로고    scopus 로고
    • Post-infectious sequelae of travelers’ diarrhea
    • PID: 2399257
    • Connor BA, Riddle MS. Post-infectious sequelae of travelers’ diarrhea. J Travel Med. 2013;20(5):303–12. doi:10.1111/jtm.12049.
    • (2013) J Travel Med , vol.20 , Issue.5 , pp. 303-312
    • Connor, B.A.1    Riddle, M.S.2
  • 50
    • 84979283381 scopus 로고
    • (Second Edition.) By Sir Arthur Hurst … with the Co-operation of H.W. Barber … H.B.F. Dixon … F.A. Knott … T.A. Ross … and Arnold W. Stott. London; 1941. Not a recent publication but this 100 year old treatise in the 2nd edition of Medical Diseases of War is the first known written description of what we now know as Post Infectious Irritable Bowel Syndrom
    • HURST AFH. Medical Diseases of War. (Second Edition.) By Sir Arthur Hurst … with the Co-operation of H.W. Barber … H.B.F. Dixon … F.A. Knott … T.A. Ross … and Arnold W. Stott. London; 1941. Not a recent publication but this 100 year old treatise in the 2nd edition of Medical Diseases of War is the first known written description of what we now know as Post Infectious Irritable Bowel Syndrome
    • (1941) HURST AFH. Medical Diseases of War
  • 51
    • 84925557459 scopus 로고
    • The irritable colon syndrome. A study of the clinical features, predisposing causes, and prognosis in 130 cases
    • COI: 1:STN:280:DyaF38%2FhvFOmsA%3D%3D, PID: 1387845
    • Chaudhary NA, Truelove SC. The irritable colon syndrome. A study of the clinical features, predisposing causes, and prognosis in 130 cases. Q J Med. 1962;31:307–22.
    • (1962) Q J Med , vol.31 , pp. 307-322
    • Chaudhary, N.A.1    Truelove, S.C.2
  • 52
    • 0001219390 scopus 로고
    • Post-dysenteric colitis
    • COI: 1:STN:280:DyaG3c%2FhvFOlug%3D%3D, PID: 1541013
    • Stewart GT. Post-dysenteric colitis. Br Med J. 1950;1(4650):405–9.
    • (1950) Br Med J , vol.1 , Issue.4650 , pp. 405-409
    • Stewart, G.T.1
  • 53
    • 84929133994 scopus 로고    scopus 로고
    • Systematic review with meta-analysis: post-infectious irritable bowel syndrome after travellers’ diarrhoea
    • COI: 1:STN:280:DC%2BC2MjjslOqtA%3D%3D, PID: 25871571, In this systematic review encompassing six well-designed observational studies, the authors make a strong association between the occurrence of TD and the development of PI-IB
    • Schwille-Kiuntke J, Mazurak N, Enck P. Systematic review with meta-analysis: post-infectious irritable bowel syndrome after travellers’ diarrhoea. Aliment Pharmacol Ther. 2015;41(11):1029–37. doi:10.1111/apt.13199. In this systematic review encompassing six well-designed observational studies, the authors make a strong association between the occurrence of TD and the development of PI-IBS.
    • (2015) Aliment Pharmacol Ther , vol.41 , Issue.11 , pp. 1029-1037
    • Schwille-Kiuntke, J.1    Mazurak, N.2    Enck, P.3
  • 55
    • 84878430175 scopus 로고    scopus 로고
    • Postinfectious functional gastrointestinal disorders: a focus on epidemiology and research agendas
    • Deising A, Gutierrez RL, Porter CK, Riddle MS. Postinfectious functional gastrointestinal disorders: a focus on epidemiology and research agendas. Gastroenterol Hepatol. 2013;9(3):145–57.
    • (2013) Gastroenterol Hepatol , vol.9 , Issue.3 , pp. 145-157
    • Deising, A.1    Gutierrez, R.L.2    Porter, C.K.3    Riddle, M.S.4
  • 56
    • 80955163708 scopus 로고    scopus 로고
    • Until the lab takes it away from epidemiology
    • PID: 2182449
    • Morabia A. Until the lab takes it away from epidemiology. Prev Med. 2011;53(4–5):217–20. doi:10.1016/j.ypmed.2011.07.018.
    • (2011) Prev Med , vol.53 , Issue.4-5 , pp. 217-220
    • Morabia, A.1
  • 57
    • 70350566110 scopus 로고    scopus 로고
    • The putative role of the intestinal microbiota in the irritable bowel syndrome
    • COI: 1:STN:280:DC%2BD1MjksVaksQ%3D%3D, PID: 1974071
    • Collins SM, Denou E, Verdu EF, Bercik P. The putative role of the intestinal microbiota in the irritable bowel syndrome. Dig Liver Dis. 2009;41(12):850–3. doi:10.1016/j.dld.2009.07.023.
    • (2009) Dig Liver Dis , vol.41 , Issue.12 , pp. 850-853
    • Collins, S.M.1    Denou, E.2    Verdu, E.F.3    Bercik, P.4
  • 58
    • 80053911536 scopus 로고    scopus 로고
    • Intestinal dendritic cells in the pathogenesis of inflammatory bowel disease
    • COI: 1:CAS:528:DC%2BC3MXhtl2mur%2FF, PID: 2198761
    • Rutella S, Locatelli F. Intestinal dendritic cells in the pathogenesis of inflammatory bowel disease. World J Gastroenterol. 2011;17(33):3761–75. doi:10.3748/wjg.v17.i33.3761.
    • (2011) World J Gastroenterol , vol.17 , Issue.33 , pp. 3761-3775
    • Rutella, S.1    Locatelli, F.2
  • 59
    • 79952763660 scopus 로고    scopus 로고
    • Epithelial crosstalk at the microbiota-mucosal interface
    • COI: 1:CAS:528:DC%2BC3MXjvVCkurc%3D, PID: 2082644
    • Wells JM, Rossi O, Meijerink M, van Baarlen P. Epithelial crosstalk at the microbiota-mucosal interface. Proc Natl Acad Sci U S A. 2011;108 Suppl 1:4607–14. doi:10.1073/pnas.1000092107.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4607-4614
    • Wells, J.M.1    Rossi, O.2    Meijerink, M.3    van Baarlen, P.4
  • 60
    • 79953086768 scopus 로고    scopus 로고
    • Gene, environment, and brain-gut interactions in irritable bowel syndrome
    • COI: 1:CAS:528:DC%2BC3MXmt1Gktro%3D, PID: 2144372
    • Fukudo S, Kanazawa M. Gene, environment, and brain-gut interactions in irritable bowel syndrome. J Gastroenterol Hepatol. 2011;26 Suppl 3:110–5. doi:10.1111/j.1440-1746.2011.06631.x.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 110-115
    • Fukudo, S.1    Kanazawa, M.2
  • 61
    • 70350658232 scopus 로고    scopus 로고
    • Pathogenic mechanisms of postinfectious functional gastrointestinal disorders: results 3 years after gastroenteritis
    • COI: 1:CAS:528:DC%2BD1MXhsVehtrnE, PID: 19711225, Several putative pathogenetic mechanisms of PI-IBS are explored including brain-gut immune dysregulation, loss of epithelial barrier integrity and innate defects in immunit
    • Mearin F, Perello A, Balboa A, Perona M, Sans M, Salas A, et al. Pathogenic mechanisms of postinfectious functional gastrointestinal disorders: results 3 years after gastroenteritis. Scand J Gastroenterol. 2009;44(10):1173–85. doi:10.1080/00365520903171276. Several putative pathogenetic mechanisms of PI-IBS are explored including brain-gut immune dysregulation, loss of epithelial barrier integrity and innate defects in immunity.
    • (2009) Scand J Gastroenterol , vol.44 , Issue.10 , pp. 1173-1185
    • Mearin, F.1    Perello, A.2    Balboa, A.3    Perona, M.4    Sans, M.5    Salas, A.6
  • 62
    • 67651108730 scopus 로고    scopus 로고
    • The clinical course of post-infectious irritable bowel syndrome: a five-year follow-up study
    • Jung IS, Kim HS, Park H, Lee SL. The clinical course of post-infectious irritable bowel syndrome: a five-year follow-up study. J Clin Gastroenterol. 2009;43:7.
    • (2009) J Clin Gastroenterol , vol.43 , pp. 7
    • Jung, I.S.1    Kim, H.S.2    Park, H.3    Lee, S.L.4
  • 63
    • 84863717585 scopus 로고    scopus 로고
    • Chronic gastrointestinal consequences of acute infectious diarrhea: evolving concepts in epidemiology and pathogenesis
    • PID: 2250814
    • Verdu EF, Riddle MS. Chronic gastrointestinal consequences of acute infectious diarrhea: evolving concepts in epidemiology and pathogenesis. Am J Gastroenterol. 2012;107(7):981–9. doi:10.1038/ajg.2012.65.
    • (2012) Am J Gastroenterol , vol.107 , Issue.7 , pp. 981-989
    • Verdu, E.F.1    Riddle, M.S.2
  • 64
    • 84855454374 scopus 로고    scopus 로고
    • Cytokines and irritable bowel syndrome: where do we stand?
    • COI: 1:CAS:528:DC%2BC38XlsVKrtQ%3D%3D, PID: 2217871
    • Bashashati M, Rezaei N, Andrews CN, Chen CQ, Daryani NE, Sharkey KA, et al. Cytokines and irritable bowel syndrome: where do we stand? Cytokine. 2012;57(2):201–9. doi:10.1016/j.cyto.2011.11.019.
    • (2012) Cytokine , vol.57 , Issue.2 , pp. 201-209
    • Bashashati, M.1    Rezaei, N.2    Andrews, C.N.3    Chen, C.Q.4    Daryani, N.E.5    Sharkey, K.A.6
  • 65
    • 80054036384 scopus 로고    scopus 로고
    • Intestinal dysbiosis in inflammatory bowel disease
    • PID: 2198306
    • Kaur N, Chen CC, Luther J, Kao JY. Intestinal dysbiosis in inflammatory bowel disease. Gut Microbes. 2011;2(4):211–6. doi:10.4161/gmic.2.4.17863.
    • (2011) Gut Microbes , vol.2 , Issue.4 , pp. 211-216
    • Kaur, N.1    Chen, C.C.2    Luther, J.3    Kao, J.Y.4
  • 66
    • 79960818162 scopus 로고    scopus 로고
    • Unraveling the ties between celiac disease and intestinal microbiota
    • PID: 2178722
    • Sanz Y, De Pama G, Laparra M. Unraveling the ties between celiac disease and intestinal microbiota. Int Rev Immunol. 2011;30(4):207–18. doi:10.3109/08830185.2011.599084.
    • (2011) Int Rev Immunol , vol.30 , Issue.4 , pp. 207-218
    • Sanz, Y.1    De Pama, G.2    Laparra, M.3
  • 67
    • 84896825642 scopus 로고    scopus 로고
    • Unraveling the ties between irritable bowel syndrome and intestinal microbiota
    • PID: 2462758
    • Hong SN, Rhee PL. Unraveling the ties between irritable bowel syndrome and intestinal microbiota. World J Gastroenterol. 2014;20(10):2470–81. doi:10.3748/wjg.v20.i10.2470.
    • (2014) World J Gastroenterol , vol.20 , Issue.10 , pp. 2470-2481
    • Hong, S.N.1    Rhee, P.L.2
  • 68
    • 80054857288 scopus 로고    scopus 로고
    • Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome
    • COI: 1:CAS:528:DC%2BC3MXhtlOksbrN, PID: 2182099
    • Rajilic-Stojanovic M, Biagi E, Heilig HG, Kajander K, Kekkonen RA, Tims S, et al. Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. Gastroenterology. 2011;141(5):1792–801. doi:10.1053/j.gastro.2011.07.043.
    • (2011) Gastroenterology , vol.141 , Issue.5 , pp. 1792-1801
    • Rajilic-Stojanovic, M.1    Biagi, E.2    Heilig, H.G.3    Kajander, K.4    Kekkonen, R.A.5    Tims, S.6
  • 69
    • 80054855719 scopus 로고    scopus 로고
    • Bugs, stool, and the irritable bowel syndrome: too much is as bad as too little?
    • PID: 2194505
    • Talley NJ, Fodor AA. Bugs, stool, and the irritable bowel syndrome: too much is as bad as too little? Gastroenterology. 2011;141(5):1555–9. doi:10.1053/j.gastro.2011.09.019.
    • (2011) Gastroenterology , vol.141 , Issue.5 , pp. 1555-1559
    • Talley, N.J.1    Fodor, A.A.2
  • 70
    • 84890985732 scopus 로고    scopus 로고
    • Faecal microbiota composition and host-microbe cross-talk following gastroenteritis and in postinfectious irritable bowel syndrome
    • PID: 2431026
    • Jalanka-Tuovinen J, Salojarvi J, Salonen A, Immonen O, Garsed K, Kelly FM, et al. Faecal microbiota composition and host-microbe cross-talk following gastroenteritis and in postinfectious irritable bowel syndrome. Gut. 2013. doi:10.1136/gutjnl-2013-305994.
    • (2013) Gut
    • Jalanka-Tuovinen, J.1    Salojarvi, J.2    Salonen, A.3    Immonen, O.4    Garsed, K.5    Kelly, F.M.6
  • 71
    • 77949263115 scopus 로고    scopus 로고
    • Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions
    • PID: 2010125
    • Ohman L, Simren M. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nat Rev Gastroenterol Hepatol. 2010;7(3):163–73. doi:10.1038/nrgastro.2010.4.
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , Issue.3 , pp. 163-173
    • Ohman, L.1    Simren, M.2
  • 72
    • 82055172236 scopus 로고    scopus 로고
    • Campylobacter jejuni induces transcytosis of commensal bacteria across the intestinal epithelium through M-like cells
    • PID: 2104054
    • Kalischuk LD, Leggett F, Inglis GD. Campylobacter jejuni induces transcytosis of commensal bacteria across the intestinal epithelium through M-like cells. Gut Pathog. 2010;2:14. doi:10.1186/1757-4749-2-14.
    • (2010) Gut Pathog , vol.2 , pp. 14
    • Kalischuk, L.D.1    Leggett, F.2    Inglis, G.D.3
  • 73
    • 84866436436 scopus 로고    scopus 로고
    • Acute gastrointestinal infection induces long-lived microbiota-specific T cell responses
    • COI: 1:CAS:528:DC%2BC38XhtlGrur7L, PID: 22923434, Elegant work showing induction of microbiota specific T cell responses in mice by Toxoplasma gondii. This provides a template for how enteric infections affect T cell responses and the potential for primed T cell to proliferate following a subsequent exposur
    • Hand TW, Dos Santos LM, Bouladoux N, Molloy MJ, Pagan AJ, Pepper M, et al. Acute gastrointestinal infection induces long-lived microbiota-specific T cell responses. Science. 2012;337(6101):1553–6. doi:10.1126/science.1220961. Elegant work showing induction of microbiota specific T cell responses in mice by Toxoplasma gondii. This provides a template for how enteric infections affect T cell responses and the potential for primed T cell to proliferate following a subsequent exposure.
    • (2012) Science , vol.337 , Issue.6101 , pp. 1553-1556
    • Hand, T.W.1    Dos Santos, L.M.2    Bouladoux, N.3    Molloy, M.J.4    Pagan, A.J.5    Pepper, M.6
  • 74
    • 84898800643 scopus 로고    scopus 로고
    • Persistent abdominal symptoms in US adults after short-term stay in Mexico
    • PID: 2462100
    • Nair P, Okhuysen PC, Jiang ZD, Carlin LG, Belkind-Gerson J, Flores J, et al. Persistent abdominal symptoms in US adults after short-term stay in Mexico. J Travel Med. 2014;21(3):153–8. doi:10.1111/jtm.12114.
    • (2014) J Travel Med , vol.21 , Issue.3 , pp. 153-158
    • Nair, P.1    Okhuysen, P.C.2    Jiang, Z.D.3    Carlin, L.G.4    Belkind-Gerson, J.5    Flores, J.6
  • 75
    • 84979228081 scopus 로고    scopus 로고
    • Use of a patch containing heat-labile toxin from Escherichia coli against travellers’ diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial
    • Frech S. Use of a patch containing heat-labile toxin from Escherichia coli against travellers’ diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial. 42nd US Japan Cholera Conference; December 2007; Austin. 2007.
    • (2007) 42nd US Japan Cholera Conference; December 2007; Austin
    • Frech, S.1
  • 76
    • 44949230030 scopus 로고    scopus 로고
    • Use of a patch containing heat-labile toxin from Escherichia coli against travellers’ diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial
    • COI: 1:CAS:528:DC%2BD1cXnt1Smsbk%3D, PID: 1855471
    • Frech SA, Dupont HL, Bourgeois AL, McKenzie R, Belkind-Gerson J, Figueroa JF, et al. Use of a patch containing heat-labile toxin from Escherichia coli against travellers’ diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial. Lancet. 2008;371(9629):2019–25. doi:10.1016/S0140-6736(08)60839-9.
    • (2008) Lancet , vol.371 , Issue.9629 , pp. 2019-2025
    • Frech, S.A.1    Dupont, H.L.2    Bourgeois, A.L.3    McKenzie, R.4    Belkind-Gerson, J.5    Figueroa, J.F.6
  • 77
    • 79955649980 scopus 로고    scopus 로고
    • Induction of increased permeability of polarized enterocyte monolayers by enterotoxigenic Escherichia coli heat-labile enterotoxin
    • PID: 2136398
    • Kreisberg RB, Harper J, Strauman MC, Marohn M, Clements JD, Nataro JP. Induction of increased permeability of polarized enterocyte monolayers by enterotoxigenic Escherichia coli heat-labile enterotoxin. Am J Trop Med Hyg. 2011;84(3):451–5. doi:10.4269/ajtmh.2011.10-0445.
    • (2011) Am J Trop Med Hyg , vol.84 , Issue.3 , pp. 451-455
    • Kreisberg, R.B.1    Harper, J.2    Strauman, M.C.3    Marohn, M.4    Clements, J.D.5    Nataro, J.P.6
  • 78
    • 72449165391 scopus 로고    scopus 로고
    • Toxin-mediated effects on the innate mucosal defenses: implications for enteric vaccines
    • COI: 1:CAS:528:DC%2BD1MXhsFGht7nN, PID: 1973790
    • Glenn GM, Francis DH, Danielsen EM. Toxin-mediated effects on the innate mucosal defenses: implications for enteric vaccines. Infect Immun. 2009;77(12):5206–15. doi:10.1128/IAI.00712-09.
    • (2009) Infect Immun , vol.77 , Issue.12 , pp. 5206-5215
    • Glenn, G.M.1    Francis, D.H.2    Danielsen, E.M.3
  • 79
    • 0042430426 scopus 로고    scopus 로고
    • Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation
    • COI: 1:CAS:528:DC%2BD3sXmsVOrt7s%3D, PID: 1292838
    • Lavelle EC, McNeela E, Armstrong ME, Leavy O, Higgins SC, Mills KH. Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation. J Immunol. 2003;171(5):2384–92.
    • (2003) J Immunol , vol.171 , Issue.5 , pp. 2384-2392
    • Lavelle, E.C.1    McNeela, E.2    Armstrong, M.E.3    Leavy, O.4    Higgins, S.C.5    Mills, K.H.6
  • 80
    • 0023938398 scopus 로고
    • Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens
    • COI: 1:STN:280:DyaL1czjslyksg%3D%3D, PID: 304801
    • Clements JD, Hartzog NM, Lyon FL. Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. Vaccine. 1988;6(3):269–77.
    • (1988) Vaccine , vol.6 , Issue.3 , pp. 269-277
    • Clements, J.D.1    Hartzog, N.M.2    Lyon, F.L.3
  • 81
    • 84937965074 scopus 로고    scopus 로고
    • Autoimmunity links vinculin to the pathophysiology of chronic functional bowel changes following campylobacter jejuni infection in a Rat model
    • COI: 1:CAS:528:DC%2BC2cXhvFyjtr%2FO, PID: 25424202, The authors postulate a mechanism for post Camplyobacter SIBO whereby mimicry between the cytolethal distending toxin of Campylobacter and the host cellprotein vinculin results in this clinical outcom
    • Pimentel M, Morales W, Pokkunuri V, Brikos C, Kim SM, Kim SE, et al. Autoimmunity links vinculin to the pathophysiology of chronic functional bowel changes following campylobacter jejuni infection in a Rat model. Dig Dis Sci. 2015;60(5):1195–205. doi:10.1007/s10620-014-3435-5. The authors postulate a mechanism for post Camplyobacter SIBO whereby mimicry between the cytolethal distending toxin of Campylobacter and the host cellprotein vinculin results in this clinical outcome.
    • (2015) Dig Dis Sci , vol.60 , Issue.5 , pp. 1195-1205
    • Pimentel, M.1    Morales, W.2    Pokkunuri, V.3    Brikos, C.4    Kim, S.M.5    Kim, S.E.6
  • 82
    • 84872871624 scopus 로고    scopus 로고
    • Role of cytolethal distending toxin in altered stool form and bowel phenotypes in a rat model of post-infectious irritable bowel syndrome
    • PID: 2310600
    • Pokkunuri V, Pimentel M, Morales W, Jee SR, Alpern J, Weitsman S, et al. Role of cytolethal distending toxin in altered stool form and bowel phenotypes in a rat model of post-infectious irritable bowel syndrome. J Neurogastroenterol Motil. 2012;18(4):434–42. doi:10.5056/jnm.2012.18.4.434.
    • (2012) J Neurogastroenterol Motil , vol.18 , Issue.4 , pp. 434-442
    • Pokkunuri, V.1    Pimentel, M.2    Morales, W.3    Jee, S.R.4    Alpern, J.5    Weitsman, S.6
  • 83
    • 80054736930 scopus 로고    scopus 로고
    • Acute and chronic histological changes of the small bowel secondary to C. jejuni infection in a rat model for post-infectious IBS
    • PID: 2140937
    • Morales W, Pimentel M, Hwang L, Kunkel D, Pokkunuri V, Basseri B, et al. Acute and chronic histological changes of the small bowel secondary to C. jejuni infection in a rat model for post-infectious IBS. Dig Dis Sci. 2011;56(9):2575–84. doi:10.1007/s10620-011-1662-6.
    • (2011) Dig Dis Sci , vol.56 , Issue.9 , pp. 2575-2584
    • Morales, W.1    Pimentel, M.2    Hwang, L.3    Kunkel, D.4    Pokkunuri, V.5    Basseri, B.6
  • 84
    • 79959753098 scopus 로고    scopus 로고
    • Antibiotic prophylaxis prevents the development of a post-infectious phenotype in a new rat model of post-infectious IBS
    • COI: 1:CAS:528:DC%2BC3MXntlaju7g%3D, PID: 2122215
    • Pimentel M, Morales W, Jee SR, Low K, Hwang L, Pokkunuri V, et al. Antibiotic prophylaxis prevents the development of a post-infectious phenotype in a new rat model of post-infectious IBS. Dig Dis Sci. 2011;56(7):1962–6. doi:10.1007/s10620-010-1548-z.
    • (2011) Dig Dis Sci , vol.56 , Issue.7 , pp. 1962-1966
    • Pimentel, M.1    Morales, W.2    Jee, S.R.3    Low, K.4    Hwang, L.5    Pokkunuri, V.6
  • 85
    • 40749099050 scopus 로고    scopus 로고
    • A new rat model links two contemporary theories in irritable bowel syndrome
    • PID: 1793482
    • Pimentel M, Chatterjee S, Chang C, Low K, Song Y, Liu C, et al. A new rat model links two contemporary theories in irritable bowel syndrome. Dig Dis Sci. 2008;53(4):982–9. doi:10.1007/s10620-007-9977-z.
    • (2008) Dig Dis Sci , vol.53 , Issue.4 , pp. 982-989
    • Pimentel, M.1    Chatterjee, S.2    Chang, C.3    Low, K.4    Song, Y.5    Liu, C.6
  • 86
    • 84934805769 scopus 로고    scopus 로고
    • Immunological biomarkers in postinfectious irritable bowel syndrome
    • PID: 26058758, A small but important study utilizing serum from the Department of Defense Repository identifying analagous anti-vinculin immune responses in post campylobacter IBS but not in IBS associated with other pathogen
    • Pike BL, Paden KA, Alcala AN, Jaep KM, Gormley RP, Maue AC, et al. Immunological biomarkers in postinfectious irritable bowel syndrome. J Travel Med. 2015;22(4):242–50. doi:10.1111/jtm.12218. A small but important study utilizing serum from the Department of Defense Repository identifying analagous anti-vinculin immune responses in post campylobacter IBS but not in IBS associated with other pathogens.
    • (2015) J Travel Med , vol.22 , Issue.4 , pp. 242-250
    • Pike, B.L.1    Paden, K.A.2    Alcala, A.N.3    Jaep, K.M.4    Gormley, R.P.5    Maue, A.C.6
  • 87
    • 84944268275 scopus 로고    scopus 로고
    • Regulators of gut motility revealed by a gnotobiotic model of diet-microbiome interactions related to travel
    • COI: 1:CAS:528:DC%2BC2MXhsFKqtrrK, PID: 26406373, In one of the few studies showing the potential effects of diet on the human microbiome in travel, the authors use a gnotobiotic mouse model to evaluate short-term dietary changes on the gut microbiota and intestinal transit times
    • Dey N, Wagner VE, Blanton LV, Cheng J, Fontana L, Haque R, et al. Regulators of gut motility revealed by a gnotobiotic model of diet-microbiome interactions related to travel. Cell. 2015;163(1):95–107. doi:10.1016/j.cell.2015.08.059. In one of the few studies showing the potential effects of diet on the human microbiome in travel, the authors use a gnotobiotic mouse model to evaluate short-term dietary changes on the gut microbiota and intestinal transit times.
    • (2015) Cell , vol.163 , Issue.1 , pp. 95-107
    • Dey, N.1    Wagner, V.E.2    Blanton, L.V.3    Cheng, J.4    Fontana, L.5    Haque, R.6
  • 88
    • 0034045571 scopus 로고    scopus 로고
    • Prebiotics and probiotics: are they functional foods?
    • COI: 1:CAS:528:DC%2BD3cXjvFGntrw%3D, PID: 10837317, discussion 8S-90
    • Roberfroid MB. Prebiotics and probiotics: are they functional foods? Am J Clin Nutr. 2000;71(6 Suppl):1682S–7. discussion 8S-90S.
    • (2000) Am J Clin Nutr , vol.71 , pp. 1682S-1687
    • Roberfroid, M.B.1
  • 89
    • 84966460516 scopus 로고    scopus 로고
    • In vitro selection criteria for propbiotic bacteria of human origin: correlation with in vivo findings
    • Dunne C, O’Mahoney L, Murphy L. In vitro selection criteria for propbiotic bacteria of human origin: correlation with in vivo findings. Am J Clin Nutr. 2001;73:3865–925.
    • (2001) Am J Clin Nutr , vol.73 , pp. 3865-3925
    • Dunne, C.1    O’Mahoney, L.2    Murphy, L.3
  • 90
    • 12744273405 scopus 로고    scopus 로고
    • Dietary modulation of the human colonic microbiota: updating the concept of prebiotics
    • COI: 1:CAS:528:DC%2BD2MXht1yltr4%3D, PID: 1907993
    • Gibson GR, Probert HM, Loo JV, Rastall RA, Roberfroid MB. Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr Res Rev. 2004;17(2):259–75. doi:10.1079/NRR200479.
    • (2004) Nutr Res Rev , vol.17 , Issue.2 , pp. 259-275
    • Gibson, G.R.1    Probert, H.M.2    Loo, J.V.3    Rastall, R.A.4    Roberfroid, M.B.5
  • 91
    • 33646713927 scopus 로고    scopus 로고
    • Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials
    • PID: 1672832
    • Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black RE. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. Lancet Infect Dis. 2006;6(6):374–82. doi:10.1016/S1473-3099(06)70495-9.
    • (2006) Lancet Infect Dis , vol.6 , Issue.6 , pp. 374-382
    • Sazawal, S.1    Hiremath, G.2    Dhingra, U.3    Malik, P.4    Deb, S.5    Black, R.E.6
  • 92
    • 33846865120 scopus 로고    scopus 로고
    • Meta-analysis of probiotics for the prevention of traveler’s diarrhea
    • PID: 1729891
    • McFarland LV. Meta-analysis of probiotics for the prevention of traveler’s diarrhea. Travel Med Infect Dis. 2007;5(2):97–105. doi:10.1016/j.tmaid.2005.10.003.
    • (2007) Travel Med Infect Dis , vol.5 , Issue.2 , pp. 97-105
    • McFarland, L.V.1
  • 93
    • 0027173742 scopus 로고
    • Prevention of Travelers’ diarrhea with saccharomyces boulardii: results of a placebo controlled double-blind study
    • COI: 1:STN:280:DyaK3s3lt1ehug%3D%3D, PID: 848632
    • Kollaritsch H, Holst H, Grobara P, Wiedermann G. Prevention of Travelers’ diarrhea with saccharomyces boulardii: results of a placebo controlled double-blind study. Fortschr Med. 1993;111:152–6.
    • (1993) Fortschr Med , vol.111 , pp. 152-156
    • Kollaritsch, H.1    Holst, H.2    Grobara, P.3    Wiedermann, G.4
  • 94
    • 84979296767 scopus 로고
    • Wiedermann G. Prevention of Traveler’s Diarrhea: A Double-Blind Randomized Trial with Saccharomyces cerevisiae Hansen CBS 5926
    • Kollaritsch HH, Wiedermann G. Prevention of Traveler’s Diarrhea: A Double-Blind Randomized Trial with Saccharomyces cerevisiae Hansen CBS 5926. Travel Med: Springer Sci + Bus Med. 1989;328–32.
    • (1989) Travel Med: Springer Sci + Bus Med , pp. 328-332
    • Kollaritsch, H.H.1
  • 96
    • 0030949653 scopus 로고    scopus 로고
    • Efficacy of lactobacillus GG as a diarrheal preventive in travelers
    • PID: 981547
    • Hilton E, Kolakowski P, Singer C, Smith M. Efficacy of lactobacillus GG as a diarrheal preventive in travelers. J Travel Med. 1997;4(1):41–3. doi:10.1111/j.1708-8305.1997.tb00772.x.
    • (1997) J Travel Med , vol.4 , Issue.1 , pp. 41-43
    • Hilton, E.1    Kolakowski, P.2    Singer, C.3    Smith, M.4
  • 97
    • 76649125531 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized human study assessing the capacity of a novel galacto-oligosaccharide mixture in reducing travellers’ diarrhoea
    • COI: 1:CAS:528:DC%2BC3cXhsVWhs7w%3D, PID: 19756029, A well-controlled study of a novel galacto-oligosccharide mixture in travelers to low and high risk of TD shows a significant reduction in diarrhea in the prebiotic group as compared to those who consumed placeb
    • Drakoularakou A, Tzortzis G, Rastall RA, Gibson GR. A double-blind, placebo-controlled, randomized human study assessing the capacity of a novel galacto-oligosaccharide mixture in reducing travellers’ diarrhoea. Eur J Clin Nutr. 2010;64(2):146–52. doi:10.1038/ejcn.2009.120. A well-controlled study of a novel galacto-oligosccharide mixture in travelers to low and high risk of TD shows a significant reduction in diarrhea in the prebiotic group as compared to those who consumed placebo.
    • (2010) Eur J Clin Nutr , vol.64 , Issue.2 , pp. 146-152
    • Drakoularakou, A.1    Tzortzis, G.2    Rastall, R.A.3    Gibson, G.R.4
  • 98
    • 84966644239 scopus 로고    scopus 로고
    • Development and functional properties of Bimuno®: a second-generation prebiotic mixture
    • Tzortzis G. Development and functional properties of Bimuno®: a second-generation prebiotic mixture. Food Sci Technol Bull: Funct Foods. 2010;6(7):81–9. doi:10.1616/1476-2137.15818.
    • (2010) Food Sci Technol Bull: Funct Foods , vol.6 , Issue.7 , pp. 81-89
    • Tzortzis, G.1
  • 99
    • 84898599406 scopus 로고    scopus 로고
    • Sodium butyrate and short chain fatty acids in prevention of travellers’ diarrhoea: a randomized prospective study
    • PID: 2406390
    • Krokowicz L, Kaczmarek BF, Krokowicz P, Stojcev Z, Mackiewicz J, Walkowiak J, et al. Sodium butyrate and short chain fatty acids in prevention of travellers’ diarrhoea: a randomized prospective study. Travel Med Infect Dis. 2014;12(2):183–8. doi:10.1016/j.tmaid.2013.08.008.
    • (2014) Travel Med Infect Dis , vol.12 , Issue.2 , pp. 183-188
    • Krokowicz, L.1    Kaczmarek, B.F.2    Krokowicz, P.3    Stojcev, Z.4    Mackiewicz, J.5    Walkowiak, J.6
  • 100
    • 84893707135 scopus 로고    scopus 로고
    • Intestinal microbiota, diet and health
    • COI: 1:CAS:528:DC%2BC2cXitVaqs7k%3D, PID: 2393106
    • Power SE, O’Toole PW, Stanton C, Ross RP, Fitzgerald GF. Intestinal microbiota, diet and health. Br J Nutr. 2014;111(3):387–402. doi:10.1017/S0007114513002560.
    • (2014) Br J Nutr , vol.111 , Issue.3 , pp. 387-402
    • Power, S.E.1    O’Toole, P.W.2    Stanton, C.3    Ross, R.P.4    Fitzgerald, G.F.5
  • 101
    • 79952066324 scopus 로고    scopus 로고
    • Probiotics for treating acute infectious diarrhoea
    • Allen SJ, Martinez EG, Gregorio GV, Dans LF. . . (11):CD003048. This Cochrane analysis examined probiotics in the treatment of intestinal infectio
    • Allen SJ, Martinez EG, Gregorio GV, Dans LF. Probiotics for treating acute infectious diarrhoea. Cochrane Database Syst Rev. 2010(11):CD003048. doi:10.1002/14651858.CD003048.pub3. This Cochrane analysis examined probiotics in the treatment of intestinal infection
    • (2010) Cochrane Database Syst Rev
  • 102
    • 0019886509 scopus 로고
    • A new therapeutic alternative for the treatment of enteritis—controlled double-blind tests with the strain SF 68
    • COI: 1:STN:280:DyaL38%2FhsFGitQ%3D%3D, PID: 679261
    • Bruno F, Frigerio G. A new therapeutic alternative for the treatment of enteritis—controlled double-blind tests with the strain SF 68. Schweiz Rundsch Med Prax. 1981;70(39):1717–20.
    • (1981) Schweiz Rundsch Med Prax , vol.70 , Issue.39 , pp. 1717-1720
    • Bruno, F.1    Frigerio, G.2
  • 103
    • 0020633283 scopus 로고
    • Double-blind controlled study of the effect of the lactogenic enterococcus SF68 strain on various enterocolitis associated manifestations and on salmonella infections
    • COI: 1:STN:280:DyaL3s3os1CnsA%3D%3
    • Bruno F, Nastasi A, Bruno M. Double-blind controlled study of the effect of the lactogenic enterococcus SF68 strain on various enterocolitis associated manifestations and on salmonella infections. La Clin Ter. 1983;105(3):203–7.
    • (1983) La Clin Ter , vol.105 , Issue.3 , pp. 203-207
    • Bruno, F.1    Nastasi, A.2    Bruno, M.3
  • 104
    • 0029788058 scopus 로고    scopus 로고
    • Efficacy of SF 68 in the treatment of acute diarrhea. A placebo-controlled trial
    • COI: 1:STN:280:DyaK2s%2Fktlagug%3D%3D, PID: 888843
    • Buydens P, Debeuckelaere S. Efficacy of SF 68 in the treatment of acute diarrhea. A placebo-controlled trial. Scand J Gastroenterol. 1996;31(9):887–91.
    • (1996) Scand J Gastroenterol , vol.31 , Issue.9 , pp. 887-891
    • Buydens, P.1    Debeuckelaere, S.2
  • 105
    • 0024324983 scopus 로고
    • Double-blind report on the efficacy of lactic acid-producing Enterococcus SF68 in the prevention of antibiotic-associated diarrhoea and in the treatment of acute diarrhoea
    • COI: 1:STN:280:DyaK3c%2Fgs1ersw%3D%3D, PID: 267665
    • Wunderlich PF, Braun L, Fumagalli I, D’Apuzzo V, Heim F, Karly M, et al. Double-blind report on the efficacy of lactic acid-producing Enterococcus SF68 in the prevention of antibiotic-associated diarrhoea and in the treatment of acute diarrhoea. J Int Med Res. 1989;17(4):333–8.
    • (1989) J Int Med Res , vol.17 , Issue.4 , pp. 333-338
    • Wunderlich, P.F.1    Braun, L.2    Fumagalli, I.3    D’Apuzzo, V.4    Heim, F.5    Karly, M.6
  • 106
    • 0025175212 scopus 로고
    • A double-blind, controlled trial of bioflorin (Streptococcus faecium SF68) in adults with acute diarrhea due to Vibrio cholerae and enterotoxigenic Escherichia coli
    • COI: 1:STN:280:DyaK3czmsl2isQ%3D%3D, PID: 220366
    • Mitra AK, Rabbani GH. A double-blind, controlled trial of bioflorin (Streptococcus faecium SF68) in adults with acute diarrhea due to Vibrio cholerae and enterotoxigenic Escherichia coli. Gastroenterology. 1990;99(4):1149–52.
    • (1990) Gastroenterology , vol.99 , Issue.4 , pp. 1149-1152
    • Mitra, A.K.1    Rabbani, G.H.2
  • 107
    • 0025270817 scopus 로고
    • Saccharomyces boulardii in the treatment of acute adult diarrhoea. [Saccharomyces boulardii bei acuter Erwachsenendiarrhoea]
    • Höchter W, Chase D, Hagenhoff G. Saccharomyces boulardii in the treatment of acute adult diarrhoea. [Saccharomyces boulardii bei acuter Erwachsenendiarrhoea]. Münchener Med Wochenschr. 1990;132(12):188–92.
    • (1990) Münchener Med Wochenschr , vol.132 , Issue.12 , pp. 188-192
    • Höchter, W.1    Chase, D.2    Hagenhoff, G.3
  • 108
    • 0035341415 scopus 로고    scopus 로고
    • Probiotic Enterococcus faecium strain is a possible recipient of the vanA gene cluster
    • COI: 1:CAS:528:DC%2BD3MXktVGqu7w%3D, PID: 1130327
    • Lund B, Edlund C. Probiotic Enterococcus faecium strain is a possible recipient of the vanA gene cluster. Clin Infect Dis. 2001;32(9):1384–5. doi:10.1086/319994.
    • (2001) Clin Infect Dis , vol.32 , Issue.9 , pp. 1384-1385
    • Lund, B.1    Edlund, C.2
  • 109
    • 84909606394 scopus 로고    scopus 로고
    • Resolution of acute gastroenteritis symptoms in children and adults treated with a novel polyphenol-based prebiotic
    • PID: 2523226
    • Noguera T, Wotring R, Melville CR, Hargraves K, Kumm J, Morton JM. Resolution of acute gastroenteritis symptoms in children and adults treated with a novel polyphenol-based prebiotic. World J Gastroenterol. 2014;20(34):12301–7. doi:10.3748/wjg.v20.i34.12301.
    • (2014) World J Gastroenterol , vol.20 , Issue.34 , pp. 12301-12307
    • Noguera, T.1    Wotring, R.2    Melville, C.R.3    Hargraves, K.4    Kumm, J.5    Morton, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.