Acute and chronic histological changes of the small bowel secondary to C. Jejuni infection in a rat model for post-infectious IBS

Digestive Diseases and Sciences

Volumn 56, Issue 9, 2011, Pages 2575-2584

  Morales, Walter ^a   Pimentel, Mark ^a   Hwang, Laura ^a   Kunkel, David ^a   Pokkunuri, Venkata ^a   Basseri, Benjamin ^a   Low, Kimberly ^a   Wang, Hanlin ^a   Conklin, Jeffrey L ^a   Chang, Christopher ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Campylobacter jejuni; Cytolethal distending toxin; Irritable bowel syndrome; Small bowel

Indexed keywords

CYTOLETHAL DISTENDING TOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIUM CULTURE; CAMPYLOBACTER ENTERITIS; CONTROLLED STUDY; DISEASE SEVERITY; DUODENUM; HISTOPATHOLOGY; ILEUM; IRRITABLE COLON; JEJUNUM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE; WILD TYPE;

ACUTE DISEASE; ANIMALS; CAMPYLOBACTER INFECTIONS; CAMPYLOBACTER JEJUNI; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; INTESTINE, SMALL; IRRITABLE BOWEL SYNDROME; MALE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 80054736930     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-011-1662-6     Document Type: Article

References (38)

1. G Bommelaer T Poynard C Le Pen AF Gaudin F Maurel G Priol M Amouretti J Frexinos P Ruszniewski A El Hasnaoui 2004 Prevalence of irritable bowel syndrome (ibs) and variability of diagnostic criteria Gastroenterol Clin Biol 28 554 561 15243388 10.1016/S0399-8320(04)95011-7 (Pubitemid 38917487)
2. HB El-Serag 2003 Impact of irritable bowel syndrome: prevalence and effect on health-related quality of life Rev Gastroenterol Disord 3 S3 11 12775997
3. L Agreus K Svardsudd O Nyren G Tibblin 1995 Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability over time Gastroenterology 109 671 680 7657095 10.1016/0016-5085(95)90373-9 1:STN:280:DyaK2MzosF2hsQ%3D%3D
4. KR Neal J Hebden R Spiller 1997 Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: postal survey of patients BMJ 314 779 782 9080994 1:STN:280:DyaK2s3js1SrsA%3D%3D (Pubitemid 27117047)
5. SD Parry R Stansfield D Jelley W Gregory E Phillips JR Barton MR Welfare 2003 Is irritable bowel syndrome more common in patients presenting with bacterial gastroenteritis? A community-based, case-control study Am J Gastroenterol 98 327 331 12591050 10.1111/j.1572-0241.2003.07242.x (Pubitemid 36232381)
6. KR Neal L Barker RC Spiller 2002 Prognosis in post-infective irritable bowel syndrome: a six year follow up study Gut 51 410 413 12171965 10.1136/gut.51.3.410 1:STN:280:DC%2BD38vhvVSksQ%3D%3D
7. JP Thornley D Jenkins K Neal T Wright J Brough RC Spiller 2001 Relationship of campylobacter toxigenicity in vitro to the development of postinfectious irritable bowel syndrome J Infect Dis 184 606 609 11474430 10.1086/322845 1:STN:280:DC%2BD3Mvks1KhtA%3D%3D (Pubitemid 32783552)
8. PC Okhuysen ZD Jiang L Carlin C Forbes HL DuPont 2004 Post-diarrhea chronic intestinal symptoms and irritable bowel syndrome in North American travelers to Mexico Am J Gastroenterol 99 1774 1778 15330917 10.1111/j.1572-0241.2004.30435.x (Pubitemid 39237507)
9. F Mearin M Perez-Oliveras A Perello J Vinyet A Ibanez J Coderch M Perona 2005 Dyspepsia and irritable bowel syndrome after a salmonella gastroenteritis outbreak: one-year follow-up cohort study Gastroenterology 129 98 104 16012939 10.1053/j.gastro.2005.04.012 (Pubitemid 41002046)
10. WM Johnson H Lior 1988 A new heat-labile cytolethal distending toxin (cldt) produced by Campylobacter spp Microb Pathog 4 115 126 2849028 10.1016/0882-4010(88)90053-8 1:CAS:528:DyaL1cXitFOms7c%3D
11. CL Pickett DL Cottle EC Pesci G Bikah 1994 Cloning, sequencing, and expression of the escherichia coli cytolethal distending toxin genes Infect Immun 62 1046 1051 8112838 1:CAS:528:DyaK2cXmsVOntL8%3D (Pubitemid 24065594)
12. CL Pickett EC Pesci DL Cottle G Russell AN Erdem H Zeytin 1996 Prevalence of cytolethal distending toxin production in Campylobacter jejuni and relatedness of Campylobacter sp. Cdtb gene Infect Immun 64 2070 2078 8675309 1:CAS:528:DyaK28Xjt1Oqtbg%3D (Pubitemid 26165668)
13. DA Scott JB Kaper 1994 Cloning and sequencing of the genes encoding Escherichia coli cytolethal distending toxin Infect Immun 62 244 251 8262635 1:CAS:528:DyaK2cXht1KnurY%3D (Pubitemid 24011966)
14. E Haghjoo JE Galan 2004 Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial- internalization pathway Proc Natl Acad Sci USA 101 4614 4619 15070766 10.1073/pnas.0400932101 1:CAS:528:DC%2BD2cXjtFKisLw%3D (Pubitemid 38437459)
15. JL Smith DO Bayles 2006 The contribution of cytolethal distending toxin to bacterial pathogenesis Crit Rev Microbiol 32 227 248 17123907 10.1080/10408410601023557 1:CAS:528:DC%2BD2sXnt1SntQ%3D%3D (Pubitemid 44851409)
16. W Heywood B Henderson SP Nair 2005 Cytolethal distending toxin: creating a gap in the cell cycle J Med Microbiol 54 207 216 15713603 10.1099/jmm.0.45694- 0 1:CAS:528:DC%2BD2MXktlegsLg%3D (Pubitemid 40879610)
17. M Lara-Tejero JE Galan 2001 Cdta, cdtb, and cdtc form a tripartite complex that is required for cytolethal distending toxin activity Infect Immun 69 4358 4365 11401974 10.1128/IAI.69.7.4358-4365.2001 1:CAS:528: DC%2BD3MXkslelu7g%3D (Pubitemid 32574433)
18. X Cortes-Bratti T Frisan M Thelestam 2001 The cytolethal distending toxins induce DNA damage and cell cycle arrest Toxicon 39 1729 1736 11595635 10.1016/S0041-0101(01)00159-3 1:CAS:528:DC%2BD3MXmsVyqsL0%3D (Pubitemid 32787004)
19. M Lara-Tejero JE Galan 2002 Cytolethal distending toxin: limited damage as a strategy to modulate cellular functions Trends Microbiol 10 147 152 11864825 10.1016/S0966-842X(02)02316-8 1:CAS:528:DC%2BD38XitFyrurk%3D (Pubitemid 34178328)
20. JG Fox AB Rogers MT Whary Z Ge NS Taylor S Xu BH Horwitz SE Erdman 2004 Gastroenteritis in nf-kappab-deficient mice is produced with wild-type Campylobacter jejuni but not with C. jejuni lacking cytolethal distending toxin despite persistent colonization with both strains Infect Immun 72 1116 1125 14742559 10.1128/IAI.72.2.1116-1125.2004 1:CAS:528:DC%2BD2cXhtFGmtbg%3D (Pubitemid 38166694)
21. C Chang JF Miller 2006 Campylobacter jejuni colonization of mice with limited enteric flora Infect Immun 74 5261 5271 16926420 10.1128/IAI.01094-05 1:CAS:528:DC%2BD28Xpt1Sls7o%3D (Pubitemid 44300445)
22. M Pimentel S Chatterjee C Chang K Low Y Song C Liu W Morales L Ali S Lezcano J Conklin S Finegold 2008 A new rat model links two contemporary theories in irritable bowel syndrome Dig Dis Sci 53 982 989 17934822 10.1007/s10620-007-9977-z (Pubitemid 351379840)
23. JI Dasti AM Tareen R Lugert AE Zautner U Gross 2010 Campylobacter jejuni: a brief overview on pathogenicity-associated factors and disease-mediating mechanisms Int J Med Microbiol 300 205 211 19665925 10.1016/j.ijmm.2009.07.002 1:CAS:528:DC%2BC3cXosFels74%3D
24. Tauxe R. Incidence, trends and sources of campylobacteriosis in developed countries: an overview. The increasing incidence of human campylobacteriosis. 2001; 42-43.
25. Lastovica A, Skirrow M. Clinical significance of campylobacter and related species other than Campylobacter jejuni and C. coli. In: Nachamkin I, Blaser M, eds. Campylobacter. Washington, DC: ASM Press; 2000:89-120.
26. MJ Blaser LB Reller 1981 Campylobacter enteritis N Engl J Med 305 1444 1452 7029281 10.1056/NEJM198112103052404 1:STN:280:DyaL38%2Flsl2rug%3D%3D (Pubitemid 12240079)
27. AA Drake MJ Gilchrist JA Washington 2nd KA Huizenga RE Van Scoy 1981 Diarrhea due to Campylobacter fetus subspecies jejuni. A clinical review of 63 cases Mayo Clin Proc 56 414 423 7253703 1:STN:280:DyaL3M3ktlOjsQ%3D%3D (Pubitemid 11006816)
28. MA Karmali PC Fleming 1979 Campylobacter enteritis Can Med Assoc J 120 1525 1532 455209 1:STN:280:DyaE1M3htVyjtg%3D%3D (Pubitemid 9254550)
29. T Pitkanen A Ponka T Pettersson TU Kosunen 1983 Campylobacter enteritis in 188 hospitalized patients Arch Intern Med 143 215 219 6824388 10.1001/archinte.143.2.215 1:STN:280:DyaL3s7isFOlsA%3D%3D (Pubitemid 13188572)
30. DA Robinson 1981 Campylobacter infection R Soc Health J 101 138 140 7268012 10.1177/146642408110100404 1:STN:280:DyaL3M3ntl2ntg%3D%3D (Pubitemid 11012101)
31. RJ Johnson C Nolan SP Wang WR Shelton MJ Blaser 1984 Persistent Campylobacter jejuni infection in an immunocompromised patient Ann Intern Med 100 832 834 6721298 1:STN:280:DyaL2c3gtFajug%3D%3D (Pubitemid 14121593)
32. I Melamed Y Bujanover YS Igra D Schwartz V Zakuth Z Spirer 1983 Campylobacter enteritis in normal and immunodeficient children Am J Dis Child 137 752 753 6869333 1:STN:280:DyaL3s3ltlSktA%3D%3D (Pubitemid 13032464)
33. DM Perlman NM Ampel RB Schifman DL Cohn CM Patton ML Aguirre WL Wang MJ Blaser 1988 Persistent Campylobacter jejuni infections in patients infected with the human immunodeficiency virus (HIV) Ann Intern Med 108 540 546 3348562 1:STN:280:DyaL1c7mtFyqsQ%3D%3D
34. RO Watson V Novik D Hofreuter M Lara-Tejero JE Galan 2007 A myd88-deficient mouse model reveals a role for nramp1 in Campylobacter jejuni infection Infect Immun 75 1994 2003 17194808 10.1128/IAI.01216-06 1:CAS:528:DC%2BD2sXkt1Oht7s%3D (Pubitemid 46559469)
35. G Barbara V Stanghellini R De Giorgio C Cremon GS Cottrell D Santini G Pasquinelli AM Morselli-Labate EF Grady NW Bunnett SM Collins R Corinaldesi 2004 Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome Gastroenterology 126 693 702 14988823 10.1053/j.gastro.2003.11.055 (Pubitemid 38298317)
36. RC Spiller D Jenkins JP Thornley JM Hebden T Wright M Skinner KR Neal 2000 Increased rectal mucosal enteroendocrine cells, t lymphocytes, and increased gut permeability following acute campylobacter enteritis and in post-dysenteric irritable bowel syndrome Gut 47 804 811 11076879 10.1136/gut.47.6.804 1:STN:280:DC%2BD3M%2FmsVCquw%3D%3D
37. LS Mansfield JA Bell DL Wilson AJ Murphy HM Elsheikha VA Rathinam BR Fierro JE Linz VB Young 2007 C57bl/6 and congenic interleukin-10-deficient mice can serve as models of Campylobacter jejuni colonization and enteritis Infect Immun 75 1099 1115 17130251 10.1128/IAI.00833-06 1:CAS:528:DC%2BD2sXivV2hsbk%3D (Pubitemid 46385801)
38. C Pigrau R Bartolome B Almirante AM Planes J Gavalda A Pahissa 1997 Bacteremia due to campylobacter species: clinical findings and antimicrobial susceptibility patterns Clin Infect Dis 25 1414 1420 9431389 10.1086/516127 1:STN:280:DyaK1c%2FptlCitQ%3D%3D (Pubitemid 28022682)