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Volumn 171, Issue 5, 2003, Pages 2384-2392

Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; B7 ANTIGEN; CD134 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; CHEMOKINE; CHOLERA TOXIN; CYTOKINE; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 5; LIPOPOLYSACCHARIDE; LYMPHOCYTE SURFACE MARKER; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 0042430426     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.5.2384     Document Type: Article
Times cited : (136)

References (34)
  • 1
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More questions than answers
    • + suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2:389.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 389
    • Shevach, E.M.1
  • 2
    • 0036717722 scopus 로고    scopus 로고
    • Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases
    • McGuirk, P., and K. H. G. Mills. 2002. Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases. Trends Immunol. 23:450.
    • (2002) Trends Immunol. , vol.23 , pp. 450
    • McGuirk, P.1    Mills, K.H.G.2
  • 3
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen, Y., V. K. Kuchroo, J. Inobe, D. A. Hafler, and H. L. Weiner. 1994. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265:1237.
    • (1994) Science , vol.265 , pp. 1237
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 4
    • 0037148511 scopus 로고    scopus 로고
    • Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper type I responses by Bordetella pertussis
    • McGuirk, P., C. McCann, and K. H. G. Mills. 2002. Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type I responses by Bordetella pertussis. J. Exp. Med. 195:221.
    • (2002) J. Exp. Med. , vol.195 , pp. 221
    • McGuirk, P.1    McCann, C.2    Mills, K.H.G.3
  • 5
    • 0034055570 scopus 로고    scopus 로고
    • Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by Th3/Tr1-type cytokines IL-10 and transforming growth factor-β but not by a Th1 to Th2 shift
    • Doetze, A., J. Satoguina, G. Burchard, T. Rau, C. Loliger, B. Fleischer, and A. Hoerauf. 2000. Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by Th3/Tr1-type cytokines IL-10 and transforming growth factor-β but not by a Th1 to Th2 shift. Int. Immunol. 12:623.
    • (2000) Int. Immunol. , vol.12 , pp. 623
    • Doetze, A.1    Satoguina, J.2    Burchard, G.3    Rau, T.4    Loliger, C.5    Fleischer, B.6    Hoerauf, A.7
  • 6
    • 0037086525 scopus 로고    scopus 로고
    • CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons
    • MacDonald, A. J., M. Duffy, M. T. Brady, S. McKiernan, W. Hall, J. Hegarty, M. Curry, and K. H. G. Mills. 2002. CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons. J. Infect. Dis. 185:720.
    • (2002) J. Infect. Dis. , vol.185 , pp. 720
    • MacDonald, A.J.1    Duffy, M.2    Brady, M.T.3    McKiernan, S.4    Hall, W.5    Hegarty, J.6    Curry, M.7    Mills, K.H.G.8
  • 10
    • 0037083298 scopus 로고    scopus 로고
    • Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse Th cell-polarizing signals
    • de Jong, E. C., P. L. Vieira, P. Kalinski, J. H. Schuitemaker, Y. Tanaka, E. A. Wierenga, M. Yazdanbakhsh, and M. L. Kapsenberg. 2002. Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse Th cell-polarizing signals. J. Immunol. 168:1704.
    • (2002) J. Immunol. , vol.168 , pp. 1704
    • De Jong, E.C.1    Vieira, P.L.2    Kalinski, P.3    Schuitemaker, J.H.4    Tanaka, Y.5    Wierenga, E.A.6    Yazdanbakhsh, M.7    Kapsenberg, M.L.8
  • 11
    • 0034660408 scopus 로고    scopus 로고
    • A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells
    • Whelan, M., M. M. Harnett, K. M., Houston, V. Patel, W. Harnett, and K. P. Rigley. 2000. A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells. J. Immunol. 164:6453.
    • (2000) J. Immunol. , vol.164 , pp. 6453
    • Whelan, M.1    Harnett, M.M.2    Houston, K.M.3    Patel, V.4    Harnett, W.5    Rigley, K.P.6
  • 13
    • 0008614480 scopus 로고
    • Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site
    • Cassel, D., and Z. Selinger. 1977. Mechanism of adenylate cyclase activation by cholera toxin: inhibition of GTP hydrolysis at the regulatory site. Proc. Natl. Acad. Sci. USA 74:3307.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 3307
    • Cassel, D.1    Selinger, Z.2
  • 14
    • 0035154289 scopus 로고    scopus 로고
    • New signaling pathways for hormones and cyclic adenosine 3′,5′-monophosphate action in endocrine cells
    • Richards, J. S. 2001. New signaling pathways for hormones and cyclic adenosine 3′,5′-monophosphate action in endocrine cells. Mol. Endocrinol. 15:209.
    • (2001) Mol. Endocrinol. , vol.15 , pp. 209
    • Richards, J.S.1
  • 16
    • 0035887789 scopus 로고    scopus 로고
    • The pulmonary environment promotes Th2 cell responses after nasal-pulmonary immunization with antigen alone, but Th1 responses are induced during instances of intense immune stimulation
    • Jones, H. P., L. M. Hodge, K. Fujihashi, H. Kiyono, J. R. McGhee, and J. W. Simecka. 2001. The pulmonary environment promotes Th2 cell responses after nasal-pulmonary immunization with antigen alone, but Th1 responses are induced during instances of intense immune stimulation. J. Immunol. 167:4518.
    • (2001) J. Immunol. , vol.167 , pp. 4518
    • Jones, H.P.1    Hodge, L.M.2    Fujihashi, K.3    Kiyono, H.4    McGhee, J.R.5    Simecka, J.W.6
  • 17
    • 0033081332 scopus 로고    scopus 로고
    • Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor β1 and β2 chain expression
    • Braun, M. C., J. He, C. Y. Wu, and B. L. Kelsall. 1999. Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor β1 and β2 chain expression. J. Exp. Med. 189:541.
    • (1999) J. Exp. Med. , vol.189 , pp. 541
    • Braun, M.C.1    He, J.2    Wu, C.Y.3    Kelsall, B.L.4
  • 18
    • 0034670024 scopus 로고    scopus 로고
    • Modulation of innate and acquired immune responses by Escherichia coli heat-labile toxin: Distinct pro- and anti-inflammatory effects of the nontoxic AB complex and the enzyme activity
    • Ryan, E. J., E. McNeela, M. Pizza, R. Rappuoli, L. O'Neill, and K. H. G. Mills. 2000. Modulation of innate and acquired immune responses by Escherichia coli heat-labile toxin: distinct pro- and anti-inflammatory effects of the nontoxic AB complex and the enzyme activity. J. Immunol. 165:5750.
    • (2000) J. Immunol. , vol.165 , pp. 5750
    • Ryan, E.J.1    McNeela, E.2    Pizza, M.3    Rappuoli, R.4    O'Neill, L.5    Mills, K.H.G.6
  • 19
    • 0035851002 scopus 로고    scopus 로고
    • Nasal administration of cholera toxin (CT) suppresses clinical signs of experimental autoimmune encephalomyelitis (EAE)
    • Yura, M., I. Takahashi, S. Terawaki, T. Hiroi, M. N. Kweon, Y. Yuki, and H. Kiyono. 2001. Nasal administration of cholera toxin (CT) suppresses clinical signs of experimental autoimmune encephalomyelitis (EAE). Vaccine 20:134.
    • (2001) Vaccine , vol.20 , pp. 134
    • Yura, M.1    Takahashi, I.2    Terawaki, S.3    Hiroi, T.4    Kweon, M.N.5    Yuki, Y.6    Kiyono, H.7
  • 21
    • 0033584234 scopus 로고    scopus 로고
    • Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells
    • Iwasaki, A., and B. L. Kelsall. 1999. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J. Exp. Med. 190:229.
    • (1999) J. Exp. Med. , vol.190 , pp. 229
    • Iwasaki, A.1    Kelsall, B.L.2
  • 24
    • 0036857735 scopus 로고    scopus 로고
    • The IL-10-producing competence of Th2 cells generated in vitro is IL-4 dependent
    • Mendel, I., and E. M. Shevach. 2002. The IL-10-producing competence of Th2 cells generated in vitro is IL-4 dependent. Eur. J. Immunol. 32:3216.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 3216
    • Mendel, I.1    Shevach, E.M.2
  • 25
    • 0037114155 scopus 로고    scopus 로고
    • Hydrogen peroxide induces murine macrophage chemokine gene transcription via extracellular signal-regulated kinase- and cyclic adenosine 5′-monophosphate (cAMP)-dependent pathways: Involvement of NF-κB, activator protein 1, and cAMP response element binding protein
    • Jaramillo, M., and M. Olivier. 2002. Hydrogen peroxide induces murine macrophage chemokine gene transcription via extracellular signal-regulated kinase- and cyclic adenosine 5′-monophosphate (cAMP)-dependent pathways: involvement of NF-κB, activator protein 1, and cAMP response element binding protein. J. Immunol. 169:7026.
    • (2002) J. Immunol. , vol.169 , pp. 7026
    • Jaramillo, M.1    Olivier, M.2
  • 26
    • 0033929615 scopus 로고    scopus 로고
    • Enterotoxin adjuvants have direct effects on T cells and antigen-presenting cells that result in either interleukin-4-dependent or -independent immune responses
    • Yamamoto, M., H. Kiyono, M. N. Kweon, S. Yamamoto, K. Fujihashi, H. Kurazono, K. Imaoka, H. Bluethmann, I. Takahashi, Y. Takeda, et al. 2000. Enterotoxin adjuvants have direct effects on T cells and antigen-presenting cells that result in either interleukin-4-dependent or -independent immune responses. J. Infect. Dis. 182:180.
    • (2000) J. Infect. Dis. , vol.182 , pp. 180
    • Yamamoto, M.1    Kiyono, H.2    Kweon, M.N.3    Yamamoto, S.4    Fujihashi, K.5    Kurazono, H.6    Imaoka, K.7    Bluethmann, H.8    Takahashi, I.9    Takeda, Y.10
  • 28
    • 0034919344 scopus 로고    scopus 로고
    • Dendritic cells as a tool to induce anergic and regulatory T cells
    • Jonuleit, H., E. Schmitt, K. Steinbrink, and A. H. Enk. 2001. Dendritic cells as a tool to induce anergic and regulatory T cells. Trends Immunol. 22:394.
    • (2001) Trends Immunol. , vol.22 , pp. 394
    • Jonuleit, H.1    Schmitt, E.2    Steinbrink, K.3    Enk, A.H.4
  • 29
    • 0037237628 scopus 로고    scopus 로고
    • Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: Dependency on antigen dose and differential toll-like receptor ligation
    • Boonstra, A., C. Asselin-Paturel, M. Gilliet, C. Crain, G. Trinchieri, Y. J. Liu, and A. O'Garra. 2003. Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J. Exp. Med. 197:101.
    • (2003) J. Exp. Med. , vol.197 , pp. 101
    • Boonstra, A.1    Asselin-Paturel, C.2    Gilliet, M.3    Crain, C.4    Trinchieri, G.5    Liu, Y.J.6    O'Garra, A.7
  • 30
    • 0034670044 scopus 로고    scopus 로고
    • Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: Phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression
    • Chen, C. H., D. H. Zhang, J. M. LaPorte, and A. Ray. 2000. Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression. J. Immunol. 165:5597.
    • (2000) J. Immunol. , vol.165 , pp. 5597
    • Chen, C.H.1    Zhang, D.H.2    LaPorte, J.M.3    Ray, A.4
  • 31
    • 0037240852 scopus 로고    scopus 로고
    • Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10
    • Martin, E., B. O'Sullivan, P. Low, and R. Thomas. 2003. Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10. Immunity 18:155.
    • (2003) Immunity , vol.18 , pp. 155
    • Martin, E.1    O'Sullivan, B.2    Low, P.3    Thomas, R.4
  • 33
    • 0036025166 scopus 로고    scopus 로고
    • Inhibition of the NF-κB transcriptional activity by protein kinase A
    • Takahashi, N., T. Tetsuka, H. Uranishi, and T. Okamoto. 2002. Inhibition of the NF-κB transcriptional activity by protein kinase A. Eur. J. Biochem. 269:4559.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 4559
    • Takahashi, N.1    Tetsuka, T.2    Uranishi, H.3    Okamoto, T.4
  • 34
    • 0034743546 scopus 로고    scopus 로고
    • Role of NFκB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI
    • Yoshimura, S., J. Bondeson, F. M. Brennan, B. M. Foxwell, and M. Feldmann. 2001. Role of NFκB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI. Eur. J. Immunol. 31:1883.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1883
    • Yoshimura, S.1    Bondeson, J.2    Brennan, F.M.3    Foxwell, B.M.4    Feldmann, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.