Generating human hematopoietic stem cells in vitro –exploring endothelial to hematopoietic transition as a portal for stemness acquisition

FEBS Letters

Volumn 590, Issue 22, 2016, Pages 4126-4143

  Slukvin, Igor I ^a,b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

Author keywords

endothelial to hematopoietic transition; hemangioblast; hematopoietic development; hematopoietic stem cells; hemogenic endothleium; pluripotent stem cells

Indexed keywords

ACTIVIN A; BONE MORPHOGENETIC PROTEIN 4; CD31 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD45 ANTIGEN; CD45RA ANTIGEN; FIBROBLAST GROWTH FACTOR; INTRINSIC FACTOR; LEUKOSIALIN; OCTAMER TRANSCRIPTION FACTOR 4; STEM CELL FACTOR RECEPTOR; THY 1 ANTIGEN; TRANSCRIPTION FACTOR; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN;

ADULT HEMATOPOIETIC STEM CELL; CELL DIFFERENTIATION; CELL EXPANSION; CELL FATE; CELL MATURATION; CELL SELF-RENEWAL; CELL SPECIFICITY; CELL TRANSFORMATION; CELLULAR PARAMETERS; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; EMBRYO DEVELOPMENT; ENDOTHELIAL TO HEMATOPOIETIC TRANSITION; ENGRAFTMENT; ERYTHROMYELOID PROGENITOR; HEMANGIOBLAST; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRAAORTIC HEMATOPOIETIC CLUSTER; MICROENVIRONMENT; MOLECULAR DYNAMICS; MORPHOGENESIS; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; SOMATIC CELL; STEM CELL; STEMNESS ACQUISITION; CELL LINEAGE; CYTOLOGY; GENETICS; NUCLEAR REPROGRAMMING;

CELL DIFFERENTIATION; CELL LINEAGE; CELLULAR REPROGRAMMING; HEMANGIOBLASTS; HEMATOPOIETIC STEM CELLS; HUMANS; PLURIPOTENT STEM CELLS;

EID: 84979076996     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1002/1873-3468.12283     Document Type: Review

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