Development and validation of rapid multiresidue and multi-class analysis for antibiotics and anthelmintics in feed by ultra-high-performance liquid chromatography coupled to tandem mass spectrometry

Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment

Volumn 33, Issue 8, 2016, Pages 1312-1323

  Robert, Christelle ^a   Brasseur, Pierre Yves ^a   Dubois, Michel ^a   Delahaut, Philippe ^a   Gillard, Nathalie ^a  

^a CER Groupe   (Belgium)

Author keywords

Animal feed; anthelmintic; antibiotic; LC MS MS; multi residue analysis; validation

Indexed keywords

ANTIBIOTICS; CHROMATOGRAPHY; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SPECTROMETRY; UNCERTAINTY ANALYSIS;

ANIMAL FEED; ANTHELMINTIC; LC-MS/MS; MULTI-RESIDUE ANALYSIS; VALIDATION;

LIQUID CHROMATOGRAPHY;

AMOXICILLIN; ANTHELMINTIC AGENT; ANTIBIOTIC AGENT; CHLORTETRACYCLINE; COLISTIN; DEMECLOCYCLINE; DOXYCYCLINE; FENBENDAZOLE; FLUBENDAZOLE; IVERMECTIN; LINCOMYCIN; OXYTETRACYCLINE; SULFADIAZINE; TIAMULIN; TILMICOSIN; TRICLABENDAZOLE; TRIMETHOPRIM; ANTIINFECTIVE AGENT;

ACCURACY; ARTICLE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; PRIORITY JOURNAL; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION STUDY;

ANTHELMINTICS; ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; TANDEM MASS SPECTROMETRY;

EID: 84979032246     PISSN: 19440049     EISSN: 19440057     Source Type: Journal    
DOI: 10.1080/19440049.2016.1207808     Document Type: Article

References (52)

1. M.M.Aguilera-Luiz, R.Romero-González, P.Plaza-Bolaños, J.L.Martínez Vidal, A.Garrido Frenich 2013. Wide-scope analysis of veterinary drug and pesticide residues in animal feed by liquid chromatography coupled to quadrupole-time-of-flight mass spectrometry. Anal Bioanal Chem. 405:6543–6553.
2. B.J.Berendsen, M.W.Nielen. 2013. Selectivity in the sample preparation for the analysis of drug residues in products of animal origin using LC-MS. Trend Anal Chem. 43:229–239.
3. J.O.Boison, S.Lee, J.Matus. 2015. A multi-residue method for the determination of seven polypeptide drug residues in chicken muscle tissues by LC-MS/MS. Anal Bioanal Chem. 407:4065–4078.
4. C.Boix, M.Ibáñez, J.V.Sancho, N.León, V.Yusá, F.Hernández. 2014. Qualitative screening of 116 veterinary drugs in feed by liquid chromatography–high resolution mass spectrometry:potential application to quantitative analysis. Food Chem. 160:313–320.
5. S.Borràs, R.Companyó, M.Granados, J.Guiteras, A.M.Pérez-Vendrell, J.Brufau, M.Medina, J.Bosch. 2011. Analysis of antimicrobial agents in animal feed. Trend Anal Chem. 30:1042–1064.
6. S.Borràs, R.Companyó, J.Guiteras, J.Bosch, M.Medina, S.Termes. 2013. Multiclass method for antimicrobial analysis in animal feeds by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 405:8475–8486.
7. S.Borràs, R.Companyó, J.Guiteras. 2011. Analysis of sulfonamides in animal feeds by liquid chromatography with fluorescence detection. J Agric Food Chem. 59:5240–5247.
8. A.Boscher, C.Guignard, T.Pellet, L.Hoffmann, T.Bohn. 2010. Development of a multi-class method for the quantification of veterinary drug residues in feedingstuffs by liquid chromatography-tandem mass spectrometry. J Chromatogr A. 1217:6394–6404.
9. B.Cancho-Grande, M.Rodríguez-Comesaña, J.Simal-Gándara. 2001. Simple HPLC determination of colistin in medicated feeds by pre-column derivatization and fluorescence detection. Chromatographia. 54:481–484.
10. B.Catry, M.Cavaleri, K.Baptiste, K.Grave, K.Grein, A.Holm, J.T.Edo. 2015. Use of colistin-containing products within the European Union and European Economic Area (EU/EEA):development of resistance in animals and possible impact on human and animal health. Int J Antimicrob Ag. 46:297–306.
11. C.Cháfer-Pericás, A.Maquieira, R.Puchades, J.Miralles, A.Moreno. 2011. Multiresidue determination of antibiotics in feed and fish samples for food safety evaluation. Comparison of immunoassay vs LC-MS-MS. Food Control. 22:993–999.
12. S.Choosakoonkriang, S.Supaluknari, P.Puangkaew. 2013. High performance liquid chromatographic method for determination of colistin sulfate and its application in medicated premix and animal feed. WASET. 76:733.
13. M.Cronly, P.Behan, B.Foley, E.Malone, S.Earley, M.Gallagher, P.Shearan, L.Regan. 2010. Development and validation of a rapid multi-class method for the confirmation of fourteen prohibited medicinal additives in pig and poultry compound feed by liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 53:929–938.
14. H.de Alwis, D.N.Heller. 2010. Multiclass, multiresidue method for the detection of antibiotic residues in distillers grains by liquid chromatography and ion trap tandem mass spectrometry. J Chromatogr A. 1217:3076–3084.
15. D.A.Durden. 2007. Positive and negative electrospray LC-MS-MS methods for quantitation of the antiparasitic endectocide drugs, abamectin, doramectin, emamectin, eprinomectin, ivermectin, moxidectin and selamectin in milk. J Chromatogr B. 850:134–146.
16. [EC] European Commission. 1990. Council directive N°90/167/EC laying down the conditions governing the preparation, placing on the market and use of medicated feeding stuffs in the community. Off J Eur Comm. L92:42–48.
17. [EC] European Commission. 2002. Commission decision (EC) N° 2002/657 of 12 August 2002 implementing council directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Off J Eur Comm. L221:8–36.
18. [EC] European Commission. 2010. Evaluation of the EU legislative framework in the field of medicated feed. Final Report [Internet]. Available from:http://ec.europa.eu/food/food/animalnutrition/labelling/medicated_feed_report_20100224.pdf.
19. I.J.W.Elbers. 2014. Proficiency test for antibiotics and anthelmintics in compound feed. Wageningen Rikilt. Confidential Rikilt Report 2014-510. 44p.
20. R.Galarini, F.Diana, S.Moretti, B.Puppini, G.Saluti, L.Persic. 2014. Development and validation of a new qualitative ELISA screening for multiresidue detection of sulfonamides in food and feed. Food Control. 35:300–310.
21. R.Galarini, L.Fioroni, F.Angelucci, G.R.Tovo, E.Cristofani. 2009. Simultaneous determination of eleven quinolones in animal feed by liquid chromatography with fluorescence and ultraviolet absorbance detection. J Chromatogr A. 1216:8158–8164.
22. A.Garrido Frenich, R.Romero-González, M.M.Aguilera-Luiz. 2014. Comprehensive analysis of toxics (pesticides, veterinary drugs and mycotoxins) in food by UHPLC-MS. TrAC. 63:158–169.
23. V.Gaudin, C.Hedou, C.Soumet, E.Verdon. 2016. Evaluation and validation of a multi-residue method based on biochip technology for the simultaneous screening of six families of antibiotics in muscle and aquaculture products. Food Addit Contam A. 33:403–419.
24. M.Gaugain-Juhel, B.Delépine, S.Gautier, M.P.Fourmond, V.Gaudin, D.Hurtaud-Pessel, E.Verdon, P.Sanders. 2009. Validation of a liquid chromatographic-tandem mass spectrometry screening method to monitor 58 antibiotics in milk:qualitative approach. Food Addit Contam. 26:1459–1471.
25. F.Granados-Chinchilla, J.Sánchez, F.Garcia, C.Rodriguez. 2012. A novel green chemistry method for nonaqueous extraction and high-performance liquid chromatography detection of first-, second-, and third-generation tetracyclines, 4-epitetracycline, and tylosin in animal feeds. J Agric Food Chem. 60:7121–7128.
26. R.B.Hoff, F.Barreto, J.Melo, M.T.Martins, T.M.Pizzolato, M.D.C.R.Peralba. 2014. Scope extension validation protocol:inclusion of analytes and matrices in an LC-MS/MS sulfonamide residues method. Food Addit Contam A. 31:39–47.
27. G.Kaklamanos, U.Vincent, C.von Holst. 2013a. Multi-residue method for the detection of veterinary drugs in distillers grains by liquid chromatography-Orbitrap high resolution mass spectrometry. J Chromatogr A. 1322:38–48.
28. G.Kaklamanos, U.Vincent, C.von Holst. 2013b. Analysis of antimicrobial agents in pig feed by liquid chromatography coupled to orbitrap mass spectrometry. J Chromatogr A. 1293:60–74.
29. L.Kantiani, M.Farré, I.F.J.M.Grases, D.Barceló. 2009. Analytical methodologies for the detection of β-lactam antibiotics in milk and feed samples. Trend Anal Chem. 28:729–741.
30. L.Kantiani, M.Farré, I.F.J.M.Grases, D.Barceló. 2010. Determination of antibacterials in animal feed by pressurized liquid extraction followed by online purification and liquid chromatography-electrospray tandem mass spectrometry. Anal Bioanal Chem. 398:1195–1205.
31. A.Kaufmann, M.Widmer. 2013. Quantitative analysis of polypeptide antibiotic residues in a variety of food matrices by liquid chromatography coupled to tandem mass spectrometry. Anal Chim Acta. 797:81–88.
32. J.Kim, J.Suh, H.Cho, W.Kang. 2016. An analytical method for fast screening and confirmation of multi-class veterinary drug residues in fish and shrimp by LC-MS/MS. Food Addit Contam A. 33:420–432.
33. C.Li, Y.L.Wu, T.Yang, Y.Zhang. 2011. Rapid simultaneous determination of eight benzimidazoles in animal feed by LC-MS-MS. Chromatographia. 73:59–65.
34. R.P.Lopes, E.E.Freitas, J.F.A.Filho, E.A.Vargas, D.V.Augusti, R.Augusti. 2012a. Development and validation of a method for the determination of sulfonamides in animal feed by modified QuEChERS and LC-MS/MS analysis. Food Control. 28:192–198.
35. R.P.Lopes, R.C.Reyes, R.Romero-González, A.G.Frenich, J.L.M.Vidal. 2012b. Development and validation of a multiclass method for the determination of veterinary drug residues in chicken by ultra high performance liquid chromatography–tandem mass spectrometry. Talanta. 89:201–208.
36. H.G.J.Mol, P.Plaza-Bolaños, P.Zomer, T.C.de Rijk, A.A.M.Stolker, P.P.J.Mulder. 2008. Toward a generic extraction method for simultaneous determination of pesticides, mycotoxins, plant toxins, and veterinary drugs in feed and food matrixes. Anal Chem. 80:9450–9459.
37. S.Morales-Munoz, M.L.de Castro. 2005. Dynamic ultrasound-assisted extraction of colistin from feeds with on-line pre-column derivatization and liquid chromatography-fluorimetric detection. J Chromatogr A. 1066:1–7.
38. J.Nácher-Mestre, M.Ibáñez, R.Serrano, J.Pérez-Sánchez, F.Hernández. 2013. Qualitative screening of undesirable compounds from feeds to fish by liquid chromatography coupled to mass spectrometry. J Agric Food Chem. 61:2077–2087.
39. J.O’Mahony, M.Moloney, M.Whelan, M.Danaher. 2012. Feed additives and veterinary drugs as contaminants animal feed–the problem of cross-contamination during feed production. In:J.Fink-Gremmels, editor. Animal feed contamination:effects on livestock and food safety. Utrecht:Woodhead Publishing Series; p. 385–140.
40. C.Robert, N.Gillard, P.Y.Brasseur, G.Pierret, N.Ralet, M.Dubois, P.Delahaut. 2013. Rapid multi-residue and multi-class qualitative screening for veterinary drugs in foods of animal origin by UHPLC-MS/MS. Food Addit Contam A. 30:443–457.
41. C.Robert, N.Gillard, P.Y.Brasseur, N.Ralet, M.Dubois, P.Delahaut. 2015. Rapid multiresidue and multi-class screening for antibiotics and benzimidazoles in feed by ultra high performance liquid chromatography coupled to tandem mass spectrometry. Food Control. 50:509–515.
42. R.Seró, O.Núñez, J.Bosch, J.M.Grases, P.Rodríguez, E.Moyano, M.T.Galceran. 2015. Desorption electrospray ionization-high resolution mass spectrometry for the screening of veterinary drugs in cross-contaminated feedstuffs. Anal Bioanal Chem. 407:7369–7378.
43. A.A.M.Stolker, V.Manti, T.Zuidema, H.van Egmond, E.R.Deckers, R.Herbes, J.Hooglugt, E.Olde Heuvel, J.de Jong. 2013. Carry-over of veterinary drugs from medicated to non-medicated feeds in commercial feed manufacturing plants. Food Addit Contam A. 30:1100–1107.
44. A.A.M.Stolker, T.Zuidema, M.W.F.Nielen. 2007. Residue analysis of veterinary drugs and growth-promoting agents. Trend Anal Chem. 26:967–979.
45. C.van Poucke, K.de Keyser, A.Baltusnikiene, J.D.G.McEvoy, C.van Peteghem. 2003. Liquid chromatographic–tandem mass spectrometric detection of banned antibacterial growth promoters in animal feed. Anal Chim Acta. 483:99–109.
46. C.van Poucke, F.Dumoulin, S.Yakkundi, C.Situ, C.T.Elliott, E.M.Grutters, R.Verheijenc, R.Schiltd, S.Erikssone, C.Van Peteghem. 2006. Banned antibacterial growth promoters in animal feed:collaborative trial on the liquid chromatography–tandem mass spectrometry method developed in the feedstuffs-radius project. Anal Chim Acta. 557:204–210.
47. U.Vincent, M.Chedin, S.Yasar, C.von Holst. 2008. Determination of ionophore coccidiostats in feeding stuffs by liquid chromatography–tandem mass spectrometry. Part I. Application to targeted feed. J Pharm Biomed Anal. 47:750–775.
48. L.Wang, H.Yang, C.Zhang, Y.Mo, X.Lu. 2008. Determination of oxytetracycline, tetracycline and chloramphenicol antibiotics in animal feeds using subcritical water extraction and high performance liquid chromatography. Anal Chim Acta. 61:54–58.
49. X.Wang, Y.Su, J.Yang, K.Bian, Z.Wang, L.M.He. 2014. High-throughput screening and confirmation of 22 banned veterinary drugs in feedstuffs using LC-MS/MS and high-resolution orbitrap mass spectrometry. J Agric Food Chem. 62:516–527.
50. J.Xie, T.Peng, A.Zhu, J.He, Q.Chang, X.Hu, H.Chen, C.Fan, W.Jiang, M.Chen, et al. 2015. Multi-residue analysis of veterinary drugs, pesticides and mycotoxins in dairy products by liquid chromatography–tandem mass spectrometry using low-temperature cleanup and solid phase extraction. J Chromatogr B. 1002:19–29.
51. Y.Xu, X.Tian, C.Ren, H.Huang, X.Zhang, X.Gong, H.Liu, Z.Yu, L.Zhang. 2012. Analysis of colistin A and B in fishery products by ultra performance liquid chromatography with positive electrospray ionization tandem mass spectrometry. J Chromatogr B. 899:14–20.
52. Q.Zhou, Y.Zhang, N.Wang, L.Zhu, H.Tang. 2014. Analysis of tetracyclines in chicken tissues and dung using LC-MS coupled with ultrasound-assisted enzymatic hydrolysis. Food Control. 46:324–331.