High-throughput screening and confirmation of 22 banned veterinary drugs in feedstuffs using LC-MS/MS and high-resolution orbitrap mass spectrometry

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 2, 2014, Pages 516-527

  Wang, Xufeng ^a   Liu, Yanghong ^a   Su, Yijuan ^a   Yang, Jianwen ^a   Bian, Kui ^a   Wang, Zongnan ^a   He, Li Min ^a  

^a SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

banned drugs; confirmation; feedstuff; liquid chromatography tandem mass spectrometry; Orbitrap mass spectrometry; screening

Indexed keywords

BANNED DRUGS; CONFIRMATION; FEEDSTUFF; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; ORBITRAP MASS SPECTROMETRIES;

EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; AGRICULTURE; CHROMATOGRAPHY; DRUG PRODUCTS; LIQUIDS; PHASE SEPARATION; SCREENING; SPECTROMETRY; THROUGHPUT;

SCREENING; EXTRACTION;

FOOD ADDITIVE; VETERINARY DRUG;

ANALYSIS; ANIMAL; ANIMAL FOOD; CHINA; DRUG LEGISLATION; FOOD CONTAMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROCEDURES; REPRODUCIBILITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

ANIMAL FEED; ANIMALS; CHINA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOOD ADDITIVES; FOOD CONTAMINATION; LEGISLATION, DRUG; MASS SPECTROMETRY; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; VETERINARY DRUGS;

EID: 84892724784     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf404501j     Document Type: Article

References (20)

1. Council Directive 96/22/EC of 29 April 1996 concerning the prohibition on the use in stock-farming of certain substances having a hormonal or thyrostatic action and of β-agonists prohibits the use of certain substances for specific purposes in food-producing animals. Off. J. Eur. Communities 1996, L125, 10.
2. Bulletin 235, Ministry of Agriculture, People's Republic of China, 2002; p 27.
3. Ishii, R.; Horie, M.; Chan, W.; MacNeil, J. Multi-residue quantitation of aminoglycoside antibiotics in kidney and meat by liquid chromatography with tandem mass spectrometry Food Addit. Contam. A 2008, 25, 1509-1519
4. Olejnik, M.; Szprengier-Juszkiewicz, T.; Jedziniak, P. J. Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry J. Chromatogr., A 2009, 29, 8141-8148
5. Bittencourt, M. S.; Martins, M. T.; De Albuquerque, F. G.; Barreto, F.; Hoff, R. High-throughput multiclass screening method for antibiotic residue analysis in meat using liquid chromatography-tandem mass spectrometry: a novel minimum sample preparation procedure Food Addit. Contam. A 2012, 29, 508-516
6. Mol, H. G.; Plaza-Bolanos, P.; Zomer, P.; de Rijk, T. C.; Stolker, A. A.; Mulder, P. P. Toward a generic extraction method for simultaneous determination of pesticides, mycotoxins, plant toxins, and veterinary drugs in feed and food matrixes Anal. Chem. 2008, 80, 9450-9459
7. Boscher, A.; Guignard, C.; Pellet, T.; Hoffmann, L.; Bohn, T. Development of a multi-class method for the quantification of veterinary drug residues in feedingstuffs by liquid chromatography-tandem mass spectrometry J. Chromatogr., A 2010, 1217, 6394-6404
8. Yang, Y.; Shao, B.; Zhang, J.; Wu, Y. N.; Duan, H. J. Determination of the residues of 50 anabolic hormones in muscle, milk and liver by very-high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry J. Chromatogr., B 2009, 877, 489-496
9. Herrmann, A.; Rosén, J.; Jansson, D.; Hellen, K. E. Evaluation of a generic multi-analyte method for detection of >100 representative compounds correlated to emergency events in 19 food types by ultrahigh-pressure liquid chromatography-tandem mass spectrometry J. Chromatogr., A 2012, 1235, 115-124
10. Zhan, J.; Zhong, Y. Y.; Yu, X. J.; Peng, J. F.; Chen, S. B.; Yin, J. Y.; Zhang, J. J.; Zhu, Y. Multi-class method for determination of veterinary drug residues and other contaminants in infant formula by ultra performance liquid chromatography-tandem mass spectrometry Food Chem. 2013, 138, 827-834
11. Commission Decision of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results (2002/657/EC). Off. J. Eur. Communities 2002, L221, 8.
12. Kondrat, R. W.; McClusky, G. A.; Cooks, R. G. Multiple reaction monitoring in mass spectrometry/mass spectrometry for direct analysis of complex mixtures Anal. Chem. 1978, 50, 2017-2021
13. Lau, J. H. W.; Khoo, C. S.; Murby, J. E. Determination of clenbuterol, salbutamol, and cimaterol in bovine retina by electrospray ionization-liquid chromatography-tandem mass spectrometry J. AOAC Int. 2004, 87, 31-38
14. Fernández-Alba, A. R.; García-Reyes, J. F. UHPLC coupled with Fourier transform Orbitrap for residue analysis Trends Anal. Chem. 2008, 27, 973-990
15. Nielen, M. W. F.; Lasaroms, J. J. P.; Mulder, P. P. J.; Hende, J.; Van Rhijn, J. A.; Groot, M. J. Multi residue screening of intact testosterone esters and boldenone undecylenate in bovine hair using liquid chromatography electrospray tandem mass spectrometry J. Chromatogr., B 2006, 830, 126-134
16. Juan, C.; Igualada, C.; Moraguesa, F.; León, N.; Mañes, J. Development and validation of a liquid chromatography tandem mass spectrometry method for the analysis of beta-agonists in animal feed and drinking water J. Chromatogr., A 2010, 1217, 6061-6068
17. Kaufmann, A.; Butcher, P.; Maden, K.; Widmer, M. Quantitative multiresidue method for about 100 veterinary drugs in different meat matrices by sub 2-micron particulate high-performance liquid chromatography coupled to time of flight mass spectrometry J. Chromatogr., A 2008, 1194, 66-79
18. Stolker, A. A. M.; Rutgers, P.; Oosterink, E.; Lasaroms, J. J.; Peters, R. J.; Van Rhijn, J. A.; Nielen, M. W. Comprehensive screening and quantification of veterinary drugs in milk using UPLC-TOF-MS Anal. Bioanal. Chem. 2008, 391, 2309-2322
19. Lopez, M. I.; Pettis, J. S.; Smith, I. B.; Chu, P. S. Multiclass determination and confirmation of antibiotic residues in honey using LC-MS/MS J. Agric. Food Chem. 2008, 56, 1553-1559
20. He, L. M.; Su, Y. J.; Zeng, Z. L.; Liu, Y. H.; Huang, X. H. Determination of ractopamine and clenbuterol in feeds by gas chromatography-mass spectrometry Anim. Feed Sci. Technol. 2007, 132, 316-323