Conjugation of docetaxel with multiwalled carbon nanotubes and codelivery with piperine: Implications on pharmacokinetic profile and anticancer activity

Molecular Pharmaceutics

Volumn 13, Issue 7, 2016, Pages 2423-2432

  Raza, Kaisar ^a   Kumar, Dinesh ^a   Kiran, Chanchal ^a   Kumar, Manish ^a   Guru, Santosh Kumar ^b   Kumar, Pramod ^a   Arora, Shweta ^c   Sharma, Gajanand ^d   Bhushan, Shashi ^b   Katare, O P ^d  

^a CENTRAL UNIVERSITY OF RAJASTHAN   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^c BANASTHALI UNIVERSITY   (India)

^d PANJAB UNIVERSITY   (India)

Author keywords

adsorption; bioavailability; CYP3A4 inhibition; drug delivery; drug release; IV push; MCF 7; MDA MB 231; nanomedicine

Indexed keywords

DOCETAXEL; MULTI WALLED NANOTUBE; NANOCARRIER; PIPERINE; 1,3 BENZODIOXOLE DERIVATIVE; ALKALOID; AMIDE; ANTINEOPLASTIC AGENT; CARBON NANOTUBE; PIPERIDINE DERIVATIVE; TAXOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BREAST CANCER; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CARBOXYLATION; CONTROLLED STUDY; DRUG ADSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; EX VIVO STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; PHARMACOKINETIC PARAMETERS; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; ULTRAVIOLET RADIATION; VOLUME OF DISTRIBUTION; ZETA POTENTIAL; CHEMISTRY; MCF-7 CELL LINE; NANOMEDICINE; NANOTECHNOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES; TUMOR CELL LINE; ULTRASTRUCTURE;

ALKALOIDS; ANTINEOPLASTIC AGENTS; BENZODIOXOLES; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MCF-7 CELLS; MICROSCOPY, ELECTRON, SCANNING; NANOMEDICINE; NANOTECHNOLOGY; NANOTUBES, CARBON; PIPERIDINES; POLYUNSATURATED ALKAMIDES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TAXOIDS;

EID: 84979025824     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.6b00183     Document Type: Article

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