-
1
-
-
84937201762
-
International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): A human rights case for nephrology
-
Mehta RL, Cerdá J, Burdmann EA, Tonelli M, García-García G, Jha V, Susantitaphong P, Rocco M, Vanholder R, Sever MS, Cruz D, Jaber B, Lameire NH, Lombardi R, Lewington A, Feehally J, Finkelstein F, Levin N, Pannu N, Thomas B, Aronoff-Spencer E, Remuzzi G: International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): A human rights case for nephrology. Lancet 385: 2616-2643, 2015
-
(2015)
Lancet
, vol.385
, pp. 2616-2643
-
-
Mehta, R.L.1
Cerdá, J.2
Burdmann, E.A.3
Tonelli, M.4
García-García, G.5
Jha, V.6
Susantitaphong, P.7
Rocco, M.8
Vanholder, R.9
Sever, M.S.10
Cruz, D.11
Jaber, B.12
Lameire, N.H.13
Lombardi, R.14
Lewington, A.15
Feehally, J.16
Finkelstein, F.17
Levin, N.18
Pannu, N.19
Thomas, B.20
Aronoff-Spencer, E.21
Remuzzi, G.22
more..
-
3
-
-
84924064909
-
New insights into the mechanisms of acute kidney injury in the intensive care unit
-
Glodowski SD, Wagener G: New insights into the mechanisms of acute kidney injury in the intensive care unit. J Clin Anesth 27: 175-180, 2015
-
(2015)
J Clin Anesth
, vol.27
, pp. 175-180
-
-
Glodowski, S.D.1
Wagener, G.2
-
4
-
-
84858720357
-
Celebrating 25 years ofNF-κB research
-
Ghosh S,HaydenMS:Celebrating 25 years ofNF-κB research. Immunol Rev 246: 5-13, 2012
-
(2012)
Immunol Rev
, vol.246
, pp. 5-13
-
-
Ghosh, S.1
Hayden, M.S.2
-
5
-
-
84858744393
-
It takes two to tango: IkBs, the multifunctional partners of NF-κB
-
Hinz M, Arslan SC, Scheidereit C: It takes two to tango: IkBs, the multifunctional partners of NF-κB. Immunol Rev 246: 59-76, 2012
-
(2012)
Immunol Rev
, vol.246
, pp. 59-76
-
-
Hinz, M.1
Arslan, S.C.2
Scheidereit, C.3
-
6
-
-
84858734708
-
NF-κB and chromatin: Ten years on the path from basic mechanisms to candidate drugs
-
Natoli G: NF-κB and chromatin: Ten years on the path from basic mechanisms to candidate drugs. Immunol Rev 246: 183-192, 2012
-
(2012)
Immunol Rev
, vol.246
, pp. 183-192
-
-
Natoli, G.1
-
7
-
-
0035137324
-
Transcription factor-kappa B (NF-kappa B) and renal disease
-
Guijarro C, Egido J: Transcription factor-kappa B (NF-kappa B) and renal disease. Kidney Int 59: 415-424, 2001
-
(2001)
Kidney Int
, vol.59
, pp. 415-424
-
-
Guijarro, C.1
Egido, J.2
-
8
-
-
0034168481
-
NFkappaB decoy oligodeoxynucleotides reduce monocyte infiltration in renal allografts
-
Vos IH, Govers R, Gröne HJ, Kleij L, Schurink M, De Weger RA, Goldschmeding R, Rabelink TJ: NFkappaB decoy oligodeoxynucleotides reduce monocyte infiltration in renal allografts. FASEB J 14: 815-822, 2000
-
(2000)
FASEB J
, vol.14
, pp. 815-822
-
-
Vos, I.H.1
Govers, R.2
Gröne, H.J.3
Kleij, L.4
Schurink, M.5
De Weger, R.A.6
Goldschmeding, R.7
Rabelink, T.J.8
-
9
-
-
1342280338
-
In vivo transfection of NF-kappaB decoy oligodeoxynucleotides attenuate renal ischemia/reperfusion injury in rats
-
Cao CC, Ding XQ, Ou ZL, Liu CF, Li P, Wang L, Zhu CF: In vivo transfection of NF-kappaB decoy oligodeoxynucleotides attenuate renal ischemia/reperfusion injury in rats. Kidney Int 65: 834-845, 2004
-
(2004)
Kidney Int
, vol.65
, pp. 834-845
-
-
Cao, C.C.1
Ding, X.Q.2
Ou, Z.L.3
Liu, C.F.4
Li, P.5
Wang, L.6
Zhu, C.F.7
-
10
-
-
67649610622
-
Small interfering RNA targeting RelB protects against renal ischemia-reperfusion injury
-
Feng B, ChenG, Zheng X, Sun H, Zhang X, Zhang ZX, Xiang Y, IchimTE, Garcia B, Luke P, JevnikarAM,MinWP: Small interfering RNA targeting RelB protects against renal ischemia-reperfusion injury. Transplantation 87: 1283-1289, 2009
-
(2009)
Transplantation
, vol.87
, pp. 1283-1289
-
-
Feng, B.1
Chen, G.2
Zheng, X.3
Sun, H.4
Zhang, X.5
Zhang, Z.X.6
Xiang, Y.7
Ichim, T.E.8
Garcia, B.9
Luke, P.10
Jevnikar, A.M.11
Min, W.P.12
-
11
-
-
79954471769
-
Small interfering RNA targeting IKKb prevents renal ischemia-reperfusion injury in rats
-
Wan X, Fan L, Hu B, Yang J, Li X, Chen X, Cao C: Small interfering RNA targeting IKKb prevents renal ischemia-reperfusion injury in rats. Am J Physiol Renal Physiol 300: F857-F863, 2011
-
(2011)
Am J Physiol Renal Physiol
, vol.300
, pp. F857-F863
-
-
Wan, X.1
Fan, L.2
Hu, B.3
Yang, J.4
Li, X.5
Chen, X.6
Cao, C.7
-
12
-
-
78650866071
-
NF-κB in the regulation of epithelial homeostasis and inflammation
-
Wullaert A, Bonnet MC, Pasparakis M: NF-κB in the regulation of epithelial homeostasis and inflammation. Cell Res 21: 146-158, 2011
-
(2011)
Cell Res
, vol.21
, pp. 146-158
-
-
Wullaert, A.1
Bonnet, M.C.2
Pasparakis, M.3
-
13
-
-
21344464908
-
Activation and function of hepatocyte NF-kappaB in postischemic liver injury
-
Lentsch AB: Activation and function of hepatocyte NF-kappaB in postischemic liver injury. Hepatology 42: 216-218, 2005
-
(2005)
Hepatology
, vol.42
, pp. 216-218
-
-
Lentsch, A.B.1
-
14
-
-
0029836444
-
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice
-
Neurath MF, Pettersson S, Meyer zum Büschenfelde KH, Strober W: Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice. Nat Med 2: 998-1004, 1996
-
(1996)
Nat Med
, vol.2
, pp. 998-1004
-
-
Neurath, M.F.1
Pettersson, S.2
Meyer Zum Büschenfelde, K.H.3
Strober, W.4
-
15
-
-
38449110152
-
Cutting edge: The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis
-
Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M: Cutting edge: The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis. J Immunol 179: 2681-2685, 2007
-
(2007)
J Immunol
, vol.179
, pp. 2681-2685
-
-
Shibata, W.1
Maeda, S.2
Hikiba, Y.3
Yanai, A.4
Ohmae, T.5
Sakamoto, K.6
Nakagawa, H.7
Ogura, K.8
Omata, M.9
-
16
-
-
34047173496
-
Epithelial NEMO links innate immunity to chronic intestinal inflammation
-
Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A,Neufert C,Madison B, Gumucio D, Neurath MF, Pasparakis M: Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature 446: 557-561, 2007
-
(2007)
Nature
, vol.446
, pp. 557-561
-
-
Nenci, A.1
Becker, C.2
Wullaert, A.3
Gareus, R.4
Van Loo, G.5
Danese, S.6
Huth, M.7
Nikolaev, A.8
Neufert, C.9
Madison, B.10
Gumucio, D.11
Neurath, M.F.12
Pasparakis, M.13
-
17
-
-
0033565763
-
Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling
-
van Hogerlinden M, Rozell BL, Ahrlund-Richter L, Toftgård R: Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling. Cancer Res 59: 3299-3303, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 3299-3303
-
-
Van Hogerlinden, M.1
Rozell, B.L.2
Ahrlund-Richter, L.3
Toftgård, R.4
-
18
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano P: Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21: 70-71, 1999
-
(1999)
Nat Genet
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
19
-
-
0034740688
-
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices
-
Schmidt-Ullrich R, Aebischer T, Hülsken J, Birchmeier W, Klemm U, Scheidereit C: Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. Development 128: 3843-3853, 2001
-
(2001)
Development
, vol.128
, pp. 3843-3853
-
-
Schmidt-Ullrich, R.1
Aebischer, T.2
Hülsken, J.3
Birchmeier, W.4
Klemm, U.5
Scheidereit, C.6
-
20
-
-
80555157523
-
Cellular pathophysiology of ischemic acute kidney injury
-
Bonventre JV, Yang L: Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest 121: 4210-4221, 2011
-
(2011)
J Clin Invest
, vol.121
, pp. 4210-4221
-
-
Bonventre, J.V.1
Yang, L.2
-
21
-
-
0032743421
-
Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation
-
Daemen MA, van 't Veer C, Denecker G, Heemskerk VH, Wolfs TG, Clauss M, Vandenabeele P, Buurman WA: Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest 104: 541-549, 1999
-
(1999)
J Clin Invest
, vol.104
, pp. 541-549
-
-
Daemen, M.A.1
Van 't Veer, C.2
Denecker, G.3
Heemskerk, V.H.4
Wolfs, T.G.5
Clauss, M.6
Vandenabeele, P.7
Buurman, W.A.8
-
22
-
-
0029059060
-
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
-
Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D: Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature 376: 167-170, 1995
-
(1995)
Nature
, vol.376
, pp. 167-170
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
Ghosh, S.4
Baltimore, D.5
-
23
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P,Mootha VK,Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102: 15545-15550, 2005
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
24
-
-
84920266775
-
The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/ reperfusion
-
DessingMC, Tammaro A, Pulskens WP, Teske GJ, Butter LM, Claessen N, van Eijk M, van der Poll T, Vogl T, Roth J, Florquin S, Leemans JC: The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/ reperfusion. Kidney Int 87: 85-94, 2015
-
(2015)
Kidney Int
, vol.87
, pp. 85-94
-
-
Dessing, M.C.1
Tammaro, A.2
Pulskens, W.P.3
Teske, G.J.4
Butter, L.M.5
Claessen, N.6
Van Eijk, M.7
Van Der Poll, T.8
Vogl, T.9
Roth, J.10
Florquin, S.11
Leemans, J.C.12
-
25
-
-
34548305272
-
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertensioninduced renal damage
-
Henke N, Schmidt-Ullrich R, Dechend R, Park JK, Qadri F, Wellner M, Obst M, Gross V, Dietz R, Luft FC, Scheidereit C, Muller DN: Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertensioninduced renal damage. Circ Res 101: 268-276, 2007
-
(2007)
Circ Res
, vol.101
, pp. 268-276
-
-
Henke, N.1
Schmidt-Ullrich, R.2
Dechend, R.3
Park, J.K.4
Qadri, F.5
Wellner, M.6
Obst, M.7
Gross, V.8
Dietz, R.9
Luft, F.C.10
Scheidereit, C.11
Muller, D.N.12
-
26
-
-
74049087979
-
Inhibition of NF-kappaB ameliorates sepsis-induced downregulation of aquaporin-2/V2 receptor expression and acute renal failure in vivo
-
Höcherl K, Schmidt C, Kurt B, Bucher M: Inhibition of NF-kappaB ameliorates sepsis-induced downregulation of aquaporin-2/V2 receptor expression and acute renal failure in vivo. Am J Physiol Renal Physiol 298: F196-F204, 2010
-
(2010)
Am J Physiol Renal Physiol
, vol.298
, pp. F196-F204
-
-
Höcherl, K.1
Schmidt, C.2
Kurt, B.3
Bucher, M.4
-
27
-
-
52449107552
-
Inflammation in acute kidney injury
-
Kinsey GR, Li L, Okusa MD: Inflammation in acute kidney injury. Nephron, Exp Nephrol 109: e102-e107, 2008
-
(2008)
Nephron, Exp Nephrol
, vol.109
, pp. e102-e107
-
-
Kinsey, G.R.1
Li, L.2
Okusa, M.D.3
-
28
-
-
84893508745
-
Macrophage dynamics in AKI to CKD progression
-
KinseyGR:Macrophage dynamics in AKI to CKD progression. JAmSoc Nephrol 25: 209-211, 2014
-
(2014)
JAmSoc Nephrol
, vol.25
, pp. 209-211
-
-
Kinsey, G.R.1
-
29
-
-
1642553460
-
To be, or not to be: NF-kappaB is the answer-role of Rel/NF-kappaB in the regulation of apoptosis
-
Kucharczak J, Simmons MJ, Fan Y, Gélinas C: To be, or not to be: NF-kappaB is the answer-role of Rel/NF-kappaB in the regulation of apoptosis. Oncogene 22: 8961-8982, 2003
-
(2003)
Oncogene
, vol.22
, pp. 8961-8982
-
-
Kucharczak, J.1
Simmons, M.J.2
Fan, Y.3
Gélinas, C.4
-
30
-
-
2942534846
-
Antiapoptotic action of hypoxia-inducible factor-1 alpha in human endothelial cells
-
Yu EZ, Li YY, Liu XH, Kagan E, McCarron RM: Antiapoptotic action of hypoxia-inducible factor-1 alpha in human endothelial cells. Lab Invest 84: 553-561, 2004
-
(2004)
Lab Invest
, vol.84
, pp. 553-561
-
-
Yu, E.Z.1
Li, Y.Y.2
Liu, X.H.3
Kagan, E.4
McCarron, R.M.5
-
31
-
-
33749518516
-
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
-
Cockman ME, Lancaster DE, Stolze IP, Hewitson KS, McDonough MA, Coleman ML, Coles CH, Yu X, Hay RT, Ley SC, Pugh CW, Oldham NJ, Masson N, Schofield CJ, Ratcliffe PJ: Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH). Proc Natl Acad Sci U S A 103: 14767-14772, 2006
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14767-14772
-
-
Cockman, M.E.1
Lancaster, D.E.2
Stolze, I.P.3
Hewitson, K.S.4
McDonough, M.A.5
Coleman, M.L.6
Coles, C.H.7
Yu, X.8
Hay, R.T.9
Ley, S.C.10
Pugh, C.W.11
Oldham, N.J.12
Masson, N.13
Schofield, C.J.14
Ratcliffe, P.J.15
-
32
-
-
3242772187
-
Ischemic acute renal failure: An inflammatory disease?
-
Bonventre JV, Zuk A: Ischemic acute renal failure: an inflammatory disease? Kidney Int 66: 480-485, 2004
-
(2004)
Kidney Int
, vol.66
, pp. 480-485
-
-
Bonventre, J.V.1
Zuk, A.2
-
33
-
-
17744382390
-
Inhibition of the chemokine receptor CXCR2 prevents kidney graft function deterioration due to ischemia/reperfusion
-
CuginiD, Azzollini N, Gagliardini E, Cassis P, Bertini R, Colotta F,Noris M, Remuzzi G, Benigni A: Inhibition of the chemokine receptor CXCR2 prevents kidney graft function deterioration due to ischemia/reperfusion. Kidney Int 67: 1753-1761, 2005
-
(2005)
Kidney Int
, vol.67
, pp. 1753-1761
-
-
Cugini, D.1
Azzollini, N.2
Gagliardini, E.3
Cassis, P.4
Bertini, R.5
Colotta, F.6
Noris, M.7
Remuzzi, G.8
Benigni, A.9
-
34
-
-
0035191972
-
Neutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury
-
Miura M, Fu X, Zhang QW, Remick DG, Fairchild RL: Neutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury. Am J Pathol 159: 2137-2145, 2001
-
(2001)
Am J Pathol
, vol.159
, pp. 2137-2145
-
-
Miura, M.1
Fu, X.2
Zhang, Q.W.3
Remick, D.G.4
Fairchild, R.L.5
-
35
-
-
0024818401
-
Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes
-
Osborn L, Hession C, Tizard R, Vassallo C, Luhowskyj S, Chi-Rosso G, Lobb R: Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell 59: 1203-1211, 1989
-
(1989)
Cell
, vol.59
, pp. 1203-1211
-
-
Osborn, L.1
Hession, C.2
Tizard, R.3
Vassallo, C.4
Luhowskyj, S.5
Chi-Rosso, G.6
Lobb, R.7
-
36
-
-
0022930702
-
Inducibility of kappa immunoglobulin enhancerbinding protein Nf-kappa B by a posttranslational mechanism
-
Sen R, Baltimore D: Inducibility of kappa immunoglobulin enhancerbinding protein Nf-kappa B by a posttranslational mechanism. Cell 47: 921-928, 1986
-
(1986)
Cell
, vol.47
, pp. 921-928
-
-
Sen, R.1
Baltimore, D.2
-
37
-
-
77955644910
-
NF-kappaB in renal inflammation
-
Sanz AB, Sanchez-Niño MD, Ramos AM, Moreno JA, Santamaria B, Ruiz-Ortega M, Egido J, Ortiz A: NF-kappaB in renal inflammation. J Am Soc Nephrol 21: 1254-1262, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1254-1262
-
-
Sanz, A.B.1
Sanchez-Niño, M.D.2
Ramos, A.M.3
Moreno, J.A.4
Santamaria, B.5
Ruiz-Ortega, M.6
Egido, J.7
Ortiz, A.8
-
38
-
-
0029666306
-
NF-kappaB activity in transgenic mice: Developmental regulation and tissue specificity
-
Schmidt-Ullrich R,Mémet S, LilienbaumA, Feuillard J, Raphaël M, Israel A: NF-kappaB activity in transgenic mice: developmental regulation and tissue specificity. Development 122: 2117-2128, 1996
-
(1996)
Development
, vol.122
, pp. 2117-2128
-
-
Schmidt-Ullrich, R.1
Mémet, S.2
Lilienbaum, A.3
Feuillard, J.4
Raphaël, M.5
Israel, A.6
-
39
-
-
84902532895
-
Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types
-
Balogh A, Németh M, Koloszár I, Markó L, Przybyl L, Jinno K, Szigeti C, Heffer M, Gebhardt M, Szeberényi J, Müller DN, Sétáló G Jr, Pap M: Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types. Apoptosis 19: 1080-1098, 2014
-
(2014)
Apoptosis
, vol.19
, pp. 1080-1098
-
-
Balogh, A.1
Németh, M.2
Koloszár, I.3
Markó, L.4
Przybyl, L.5
Jinno, K.6
Szigeti, C.7
Heffer, M.8
Gebhardt, M.9
Szeberényi, J.10
Müller, D.N.11
Sétáló, G.12
Pap, M.13
-
40
-
-
84899761766
-
Type 1 angiotensin receptors on macrophages ameliorate IL-1 receptor-mediated kidney fibrosis
-
Zhang JD, Patel MB, Griffiths R, Dolber PC, Ruiz P, Sparks MA, Stegbauer J, Jin H, Gomez JA, Buckley AF, Lefler WS, Chen D, Crowley SD: Type 1 angiotensin receptors on macrophages ameliorate IL-1 receptor-mediated kidney fibrosis. J Clin Invest 124: 2198-2203, 2014
-
(2014)
J Clin Invest
, vol.124
, pp. 2198-2203
-
-
Zhang, J.D.1
Patel, M.B.2
Griffiths, R.3
Dolber, P.C.4
Ruiz, P.5
Sparks, M.A.6
Stegbauer, J.7
Jin, H.8
Gomez, J.A.9
Buckley, A.F.10
Lefler, W.S.11
Chen, D.12
Crowley, S.D.13
-
41
-
-
27944451518
-
Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent
-
Biju MP, Akai Y, Shrimanker N, Haase VH: Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent. AmJ Physiol Renal Physiol 289: F1217-F1226, 2005
-
(2005)
AmJ Physiol Renal Physiol
, vol.289
, pp. F1217-F1226
-
-
Biju, M.P.1
Akai, Y.2
Shrimanker, N.3
Haase, V.H.4
|