Neuroprotective oleanane triterpenes from the roots of Bupleurum chinense

Bioorganic and Medicinal Chemistry Letters

Volumn 26, Issue 6, 2016, Pages 1594-1598

  Li, Dan Qi ^a   Zhou, Le ^a   Wang, Di ^a   Wu, Jie ^a   Li, Ling Zhi ^a   Huang, Xiao Xiao ^a   Liu, Qing Bo ^a   Wu, Ying Ying ^a   Lin, Song ^a,b   Yang, Jing Yu ^a   Song, Shao Jiang ^a   Wu, Chun Fu ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

Author keywords

Bupleurum chinense D.C.; Cytotoxicity; Neuroprotective effects; Triterpenoids

Indexed keywords

11ALPHA METHOXYSAIKOSAPONIN F; 16ALPHA,23ALPHA,28BETA TRIHYDROXYOLEANA 11,13(18) DIENE 3 ONE; 16BETA,22ALPHA,23BETA TETRAHYDROXY 11ALPHA METHOXYLOLEAN 12 EN 3 ONE; 2'' O ACETYLSAIKOSAPONIN B2; 3BETA,23ALPHA,28BETA TRIHYDROXYOLEANA 11,13(18) DIENE 16 ONE; 6'' O ACETYLSAIKOSAPONIN B2; 6'' O ACETYLSAIKOSAPONIN B4; BUPLEUROSIDE III; BUPLEURUM CHINENSE EXTRACT; CYTOTOXIC AGENT; FLUOROURACIL; HYDROGEN PEROXIDE; NEUROPROTECTIVE AGENT; PLANT EXTRACT; PLEUROSAPONIN F; REACTIVE OXYGEN METABOLITE; SAIKOGENIN A; SAIKOGENIN D; SAIKOGENIN F; SAIKOGENIN G; SAIKOSAPONIN B2; SAIKOSAPONIN B3; SAIKOSAPONIN F; SAIKOSAPONIN T; TRITERPENE DERIVATIVE; TROLOX C; UNCLASSIFIED DRUG; OLEANOLIC ACID;

A549 CELL LINE; ARTICLE; BUPLEURUM CHINENSE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOTOXICITY; ELECTROSPRAY MASS SPECTROMETRY; HEPG2 CELL LINE; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; MCF 7 CELL LINE; NERVE CELL LESION; NEUROBLASTOMA CELL LINE; NEUROPROTECTION; NUCLEAR OVERHAUSER EFFECT; OXIDATIVE STRESS; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; TANDEM MASS SPECTROMETRY; ANTAGONISTS AND INHIBITORS; BUPLEURUM; CELL DEATH; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ISOLATION AND PURIFICATION; NERVE CELL; PATHOLOGY; TUMOR CELL LINE;

BUPLEURUM; CELL DEATH; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROGEN PEROXIDE; MOLECULAR STRUCTURE; NEURONS; NEUROPROTECTIVE AGENTS; OLEANOLIC ACID; PLANT ROOTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84978969912     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2016.02.004     Document Type: Article

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