Neuroprotective effects of Kukoamine B against hydrogen peroxide-induced apoptosis and potential mechanisms in SH-SY5Y cells

Environmental Toxicology and Pharmacology

Volumn 40, Issue 1, 2015, Pages 230-240

  Hu, Xiao Long ^a,b   Niu, Yi Xuan ^b   Zhang, Qiao ^b   Tian, Xing ^b   Gao, Ling Yue ^b   Guo, Li Ping ^b   Meng, Wei Hong ^a   Zhao, Qing Chun ^a  

^a GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Hydrogen peroxide; Kukoamine B; Neuroprotection; Oxidative stress; SH SY5Y cells

Indexed keywords

ANTIOXIDANT; CASPASE 3; CASPASE 9; CATALASE; CYTOCHROME C; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; KUKOAMINE B; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; CAFFEIC ACID DERIVATIVE; MATRIX METALLOPROTEINASE; NEUROPROTECTIVE AGENT; SPERMINE;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL MEMBRANE; CELL PROTECTION; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; DRUG EFFECTS; HUMAN; METABOLISM; TUMOR CELL LINE;

APOPTOSIS; CAFFEIC ACIDS; CASPASE 3; CASPASE 9; CATALASE; CELL LINE, TUMOR; CYTOCHROMES C; GLUTATHIONE PEROXIDASE; HUMANS; HYDROGEN PEROXIDE; MALONDIALDEHYDE; MATRIX METALLOPROTEINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SPERMINE; SUPEROXIDE DISMUTASE;

EID: 84949546540     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2015.06.017     Document Type: Article

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