Using ToxCast to explore chemical activities and hazard traits: A case study with ortho-phthalates

Toxicological Sciences

Volumn 151, Issue 2, 2016, Pages 286-301

  Pham, Nathalie ^a   Iyer, Shoba ^a   Hackett, Edward ^a   Lock, Bennett H ^a   Sandy, Martha ^a   Zeise, Lauren ^a   Solomon, Gina ^a   Marty, Melanie ^a  

^a CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Hazard traits; High throughput screening; Phthalates; ToxCast

Indexed keywords

ANDROGEN RECEPTOR; AROMATASE; AROMATIC HYDROCARBON RECEPTOR; DI(ISONONYL) PHTHALATE; DIALLYL PHTHALATE; DICYCLOHEXYL PHTHALATE; DIHEXYL PHTHALATE; DIISOBUTYL PHTHALATE; DIISODECYL PHTHALATE; DIISOPROPYL PHTHALATE; DIISOUNDECYL PHTHALATE; DIPENTYL PHTHALATE; ESTROGEN RECEPTOR; MONOBENZYL PHTHALATE; MONOBUTYL PHTHALATE; MONOMETHYL PHTHALATE; OCTYL DECYL PHTHALATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHTHALIC ACID; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID BENZYL BUTYL ESTER; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PHTHALIC ACID DIBUTYL ESTER; PHTHALIC ACID DIETHYL ESTER; PHTHALIC ACID DIMETHYL ESTER; PHTHALIC ACID DIOCTYL ESTER; PREGNANE X RECEPTOR; THYROID HORMONE RECEPTOR; UNCLASSIFIED DRUG; ENDOCRINE DISRUPTOR; PHTHALIC ACID DERIVATIVE; PLASTICIZER;

ARTICLE; DEVELOPMENTAL TOXICITY; GENOTOXICITY; HIGH THROUGHPUT SCREENING; LIVER TOXICITY; NEPHROTOXICITY; NEUROTOXICITY; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; TOXICITY ASSAY; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; FACTUAL DATABASE; FEMALE; GENE EXPRESSION REGULATION; HUMAN; MALE; REPRODUCTION; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING;

ANIMALS; DATABASES, FACTUAL; ENDOCRINE DISRUPTORS; FEMALE; GENE EXPRESSION REGULATION; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MALE; MOLECULAR STRUCTURE; PHTHALIC ACIDS; PLASTICIZERS; REPRODUCTION; RISK ASSESSMENT; STRUCTURE-ACTIVITY RELATIONSHIP; TOXICITY TESTS;

EID: 84978938016     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfw049     Document Type: Article

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