AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies

Cell

Volumn 166, Issue 3, 2016, Pages 582-595

  Meyer, Steffen ^a   Woodward, Martin ^b   Hertel, Christina ^a   Vlaicu, Philip ^a   Haque, Yasmin ^b   Kärner, Jaanika ^c   Macagno, Annalisa ^a   Onuoha, Shimobi C ^a   Fishman, Dmytro ^c,d   Peterson, Hedi ^c,d   Metsküla, Kaja ^c   Uibo, Raivo ^c   Jäntti, Kirsi ^e   Hokynar, Kati ^e   Wolff, Anette S B ^f   Meloni, Antonella ^h   Kluger, Nicolas ^h   Husebye, Eystein S ^h   Podkrajsek, Katarina Trebusak ^h   Battelino, Tadej ^h   Bratanic, Nina ^h   Peet, Aleksandr ^h   Krohn, Kai ^e   Ranki, Annamari ^g   Peterson, Pärt ^c   Kisand, Kai ^c   Hayday, Adrian ^b   more..

^a ImmunoQure   (Germany)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF TARTU   (Estonia)

^d ImmunoQure Research AG ^*  (Estonia)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^f UNIVERSITY OF BERGEN   (Norway)

^g UNIVERSITY OF HELSINKI   (Finland)

^h Helsinki University Central Hospital ^*

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOIMMUNE REGULATOR PROTEIN; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERFERON; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 1ALPHA; INTERLEUKIN 20; INTERLEUKIN 22; INTERLEUKIN 28A; INTERLEUKIN 28B; INTERLEUKIN 29; INTERLEUKIN 32; INTERLEUKIN 5; INTERLEUKIN 6; NEUTRALIZING ANTIBODY; STAT1 PROTEIN; CYTOKINE; TRANSCRIPTION FACTOR;

ADOLESCENT; ADULT; AGED; ANIMAL CELL; ANTIBODY AFFINITY; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; AUTOIMMUNE REGULATOR PROTEIN DEFICIENCY; B LYMPHOCYTE; BONE MARROW CELL; CHILD; CHO CELL LINE; CONTROLLED STUDY; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE; MAJOR CLINICAL STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; T LYMPHOCYTE; TH2 CELL; ANIMAL; C57BL MOUSE; DEFICIENCY; DISEASE RESISTANCE; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MIDDLE AGED; POLYENDOCRINOPATHY; PRESCHOOL CHILD; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODY AFFINITY; AUTOANTIBODIES; CHILD; CHILD, PRESCHOOL; CYTOKINES; DIABETES MELLITUS, TYPE 1; DISEASE RESISTANCE; HUMANS; IMMUNE TOLERANCE; MICE, INBRED C57BL; MIDDLE AGED; POLYENDOCRINOPATHIES, AUTOIMMUNE; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; YOUNG ADULT;

EID: 84978877977     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.06.024     Document Type: Article

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