-
1
-
-
84912079287
-
Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development
-
Chow, I. T. et al. Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development. PloS one 9, e112882, doi: 10.1371/journal.pone.0112882 (2014).
-
(2014)
PloS One
, vol.9
, pp. e112882
-
-
Chow, I.T.1
-
2
-
-
84863209948
-
ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes
-
Enee, E. et al. ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes. Diabetes 61, 1779-1784, doi: 10.2337/db12-0071 (2012).
-
(2012)
Diabetes
, vol.61
, pp. 1779-1784
-
-
Enee, E.1
-
3
-
-
84907020081
-
High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addisons disease patients
-
Dawoodji, A. et al. High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addisons disease patients. J Immunol 193, 2118-2126, doi: 10.4049/jimmunol.1400056 (2014).
-
(2014)
J Immunol
, vol.193
, pp. 2118-2126
-
-
Dawoodji, A.1
-
4
-
-
2342523339
-
Autoantibodies as predictors of disease
-
Scofield, R. H. Autoantibodies as predictors of disease. Lancet 363, 1544-1546, doi: 10.1016/S0140-6736(04)16154-0 (2004).
-
(2004)
Lancet
, vol.363
, pp. 1544-1546
-
-
Scofield, R.H.1
-
5
-
-
0035860499
-
Global analysis of protein activities using proteome chips
-
Zhu, H. et al. Global analysis of protein activities using proteome chips. Science 293, 2101-2105, doi: 10.1126/science.1062191 (2001).
-
(2001)
Science
, vol.293
, pp. 2101-2105
-
-
Zhu, H.1
-
6
-
-
84862321638
-
Rapid identification of monospecific monoclonal antibodies using a human proteome microarray
-
Jeong, J. S. et al. Rapid identification of monospecific monoclonal antibodies using a human proteome microarray. Molecular & cellular proteomics: MCP 11, O111 016253, doi: 10.1074/mcp.O111.016253 (2012).
-
(2012)
Molecular & Cellular Proteomics: MCP
, vol.11 O111
, pp. 016253
-
-
Jeong, J.S.1
-
7
-
-
84958774715
-
Serum profiling using protein microarrays to identify disease related antigens
-
Sharon, D. & Snyder, M. Serum profiling using protein microarrays to identify disease related antigens. Methods in molecular biology 1176, 169-178, doi: 10.1007/978-1-4939-0992-6-14 (2014).
-
(2014)
Methods in Molecular Biology
, vol.1176
, pp. 169-178
-
-
Sharon, D.1
Snyder, M.2
-
8
-
-
0025295238
-
Clinical variation of autoimmune polyendocrinopathy-candidiasisectodermal dystrophy (APECED) in a series of 68 patients
-
Ahonen, P., Myllarniemi, S., Sipila, I. & Perheentupa, J. Clinical variation of autoimmune polyendocrinopathy-candidiasisectodermal dystrophy (APECED) in a series of 68 patients. N Engl J Med 322, 1829-1836, doi: 10.1056/NEJM199006283222601 (1990).
-
(1990)
N Engl J Med
, vol.322
, pp. 1829-1836
-
-
Ahonen, P.1
Myllarniemi, S.2
Sipila, I.3
Perheentupa, J.4
-
9
-
-
33747662305
-
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
-
Perheentupa, J. Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. J Clin Endocrinol Metab 91, 2843-2850 (2006).
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2843-2850
-
-
Perheentupa, J.1
-
10
-
-
16944367194
-
Positional cloning of the APECED gene
-
Nagamine, K. et al. Positional cloning of the APECED gene. Nat Genet 17, 393-398 (1997).
-
(1997)
Nat Genet
, vol.17
, pp. 393-398
-
-
Nagamine, K.1
-
11
-
-
0346599403
-
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-Type zinc-finger domains
-
Finnish-German, A. C. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-Type zinc-finger domains. Nat Genet 17, 399-403 (1997).
-
(1997)
Nat Genet
, vol.17
, pp. 399-403
-
-
Finnish-German, A.C.1
-
12
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson, M. S. et al. Projection of an immunological self shadow within the thymus by the aire protein. Science 298, 1395-1401, doi: 10.1126/science.1075958 (2002).
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
-
13
-
-
0037383758
-
Aire regulates negative selection of organ-specific T cells
-
Liston, A., Lesage, S., Wilson, J., Peltonen, L. & Goodnow, C. C. Aire regulates negative selection of organ-specific T cells. Nature immunology 4, 350-354, doi: 10.1038/ni906 (2003).
-
(2003)
Nature Immunology
, vol.4
, pp. 350-354
-
-
Liston, A.1
Lesage, S.2
Wilson, J.3
Peltonen, L.4
Goodnow, C.C.5
-
14
-
-
22344449972
-
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
-
Derbinski, J. et al. Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J Exp Med 202, 33-45, doi: 10.1084/jem.20050471 (2005).
-
(2005)
J Exp Med
, vol.202
, pp. 33-45
-
-
Derbinski, J.1
-
15
-
-
84913594338
-
Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-Antigen expression in thymic epithelia
-
Sansom, S. N. et al. Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-Antigen expression in thymic epithelia. Genome research 24, 1918-1931, doi: 10.1101/gr.171645.113 (2014).
-
(2014)
Genome Research
, vol.24
, pp. 1918-1931
-
-
Sansom, S.N.1
-
16
-
-
56749105120
-
The variable immunological self: Genetic variation and nongenetic noise in Aire-regulated transcription
-
Venanzi, E. S., Melamed, R., Mathis, D. & Benoist, C. The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription. Proc Natl Acad Sci USA 105, 15860-15865, doi: 10.1073/pnas.0808070105 (2008).
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15860-15865
-
-
Venanzi, E.S.1
Melamed, R.2
Mathis, D.3
Benoist, C.4
-
17
-
-
0032566209
-
Identification of tryptophan hydroxylase as an intestinal autoantigen
-
Ekwall, O. et al. Identification of tryptophan hydroxylase as an intestinal autoantigen. Lancet 352, 279-283, doi: 10.1016/S0140-6736(97)11050-9 (1998).
-
(1998)
Lancet
, vol.352
, pp. 279-283
-
-
Ekwall, O.1
-
18
-
-
40449109084
-
Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen
-
Alimohammadi, M. et al. Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen. N Engl J Med 358, 1018-1028, doi: 10.1056/NEJMoa0706487 (2008).
-
(2008)
N Engl J Med
, vol.358
, pp. 1018-1028
-
-
Alimohammadi, M.1
-
19
-
-
84885461634
-
BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease
-
Shum, A. K. et al. BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease. Science translational medicine 5, 206ra139, doi: 10.1126/scitranslmed.3006998 (2013).
-
(2013)
Science Translational Medicine
, vol.5
, pp. 206-139
-
-
Shum, A.K.1
-
20
-
-
0027366956
-
Two different cytochrome P450 enzymes are the adrenal antigens in autoimmune polyendocrine syndrome type i and Addisons disease
-
Winqvist, O., Gustafsson, J., Rorsman, F., Karlsson, F. A. & Kampe, O. Two different cytochrome P450 enzymes are the adrenal antigens in autoimmune polyendocrine syndrome type I and Addisons disease. J Clin Invest 92, 2377-2385, doi: 10.1172/JCI116843 (1993).
-
(1993)
J Clin Invest
, vol.92
, pp. 2377-2385
-
-
Winqvist, O.1
Gustafsson, J.2
Rorsman, F.3
Karlsson, F.A.4
Kampe, O.5
-
21
-
-
63149126091
-
Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen
-
Alimohammadi, M. et al. Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen. Proc Natl Acad Sci USA 106, 4396-4401, doi: 10.1073/pnas.0809986106 (2009).
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4396-4401
-
-
Alimohammadi, M.1
-
22
-
-
33846528700
-
Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1
-
Bensing, S. et al. Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1. Proc Natl Acad Sci USA 104, 949-954, doi: 10.1073/pnas.0610070104 (2007).
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 949-954
-
-
Bensing, S.1
-
23
-
-
10744233772
-
Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type i
-
Soderbergh, A. et al. Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I. J Clin Endocrinol Metab 89, 557-562, doi: 10.1210/jc.2003-030279 (2004).
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 557-562
-
-
Soderbergh, A.1
-
24
-
-
84937598338
-
Dominant mutations in the autoimmune regulator AIRE Are associated with common organ-specific autoimmune diseases
-
Oftedal, B. E. et al. Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases. Immunity 42, 1185-1196, doi: 10.1016/j.immuni.2015.04.021 (2015).
-
(2015)
Immunity
, vol.42
, pp. 1185-1196
-
-
Oftedal, B.E.1
-
25
-
-
0034749749
-
A novel mutation of the autoimmune regulator gene in an Italian kindred with autoimmune polyendocrinopathycandidiasis-ectodermal dystrophy, acting in a dominant fashion and strongly cosegregating with hypothyroid autoimmune thyroiditis
-
Cetani, F. et al. A novel mutation of the autoimmune regulator gene in an Italian kindred with autoimmune polyendocrinopathycandidiasis-ectodermal dystrophy, acting in a dominant fashion and strongly cosegregating with hypothyroid autoimmune thyroiditis. J Clin Endocrinol Metab 86, 4747-4752, doi: 10.1210/jcem.86.10.7884 (2001).
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 4747-4752
-
-
Cetani, F.1
-
26
-
-
0034351867
-
Ss-cell autoantibodies, human leukocyte antigen II alleles, and type 1 diabetes in autoimmune polyendocrinopathycandidiasis-ectodermal dystrophy
-
Gylling, M. et al. ss-cell autoantibodies, human leukocyte antigen II alleles, and type 1 diabetes in autoimmune polyendocrinopathycandidiasis-ectodermal dystrophy. J Clin Endocrinol Metab 85, 4434-4440, doi: 10.1210/jcem.85.12.7120 (2000).
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 4434-4440
-
-
Gylling, M.1
-
27
-
-
0023948789
-
The expression of autoimmune polyglandular disease type i appears associated with several HLA-A antigens but not with HLA-DR
-
Ahonen, P., Koskimies, S., Lokki, M. L., Tiilikainen, A. & Perheentupa, J. The expression of autoimmune polyglandular disease type I appears associated with several HLA-A antigens but not with HLA-DR. J Clin Endocrinol Metab 66, 1152-1157, doi: 10.1210/jcem-66-6-1152 (1988).
-
(1988)
J Clin Endocrinol Metab
, vol.66
, pp. 1152-1157
-
-
Ahonen, P.1
Koskimies, S.2
Lokki, M.L.3
Tiilikainen, A.4
Perheentupa, J.5
-
28
-
-
18444378139
-
AIRE mutations and human leukocyte antigen genotypes as determinants of the autoimmune polyendocrinopathycandidiasis-ectodermal dystrophy phenotype
-
Halonen, M. et al. AIRE mutations and human leukocyte antigen genotypes as determinants of the autoimmune polyendocrinopathycandidiasis-ectodermal dystrophy phenotype. J Clin Endocrinol Metab 87, 2568-2574, doi: 10.1210/jcem.87.6.8564 (2002).
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 2568-2574
-
-
Halonen, M.1
-
29
-
-
33746423947
-
Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1
-
Meager, A. et al. Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1. PLoS medicine 3, e289, doi: 10.1371/journal.pmed.0030289 (2006).
-
(2006)
PLoS Medicine
, vol.3
, pp. e289
-
-
Meager, A.1
-
30
-
-
77149124612
-
Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type i
-
Puel, A. et al. Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J Exp Med 207, 291-297, doi: 10.1084/jem.20091983 (2010).
-
(2011)
J Exp Med
, vol.207
, pp. 291-297
-
-
Puel, A.1
-
31
-
-
77149147477
-
Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-Associated cytokines
-
Kisand, K. et al. Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-Associated cytokines. J Exp Med 207, 299-308, doi: 10.1084/jem.20091669 (2010).
-
(2011)
J Exp Med
, vol.207
, pp. 299-308
-
-
Kisand, K.1
-
32
-
-
84931466170
-
Transglutaminase 4 as a prostate autoantigen in male subfertility
-
Landegren, N. et al. Transglutaminase 4 as a prostate autoantigen in male subfertility. Science translational medicine 7, 292-101, doi: 10.1126/scitranslmed.aaa9186 (2015).
-
(2015)
Science Translational Medicine
, vol.7
, pp. 292-101
-
-
Landegren, N.1
-
33
-
-
12544251988
-
PDILT, a divergent testis-specific protein disulfide isomerase with a nonclassical SXXC motif that engages in disulfide-dependent interactions in the endoplasmic reticulum
-
van Lith, M., Hartigan, N., Hatch, J. & Benham, A. M. PDILT, a divergent testis-specific protein disulfide isomerase with a nonclassical SXXC motif that engages in disulfide-dependent interactions in the endoplasmic reticulum. The Journal of biological chemistry 280, 1376-1383, doi: 10.1074/jbc.M408651200 (2005).
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 1376-1383
-
-
Van Lith, M.1
Hartigan, N.2
Hatch, J.3
Benham, A.M.4
-
34
-
-
34547735918
-
A developmentally regulated chaperone complex for the endoplasmic reticulum of male haploid germ cells
-
van Lith, M. et al. A developmentally regulated chaperone complex for the endoplasmic reticulum of male haploid germ cells. Molecular biology of the cell 18, 2795-2804, doi: 10.1091/mbc.E07-02-0147 (2007).
-
(2007)
Molecular Biology of the Cell
, vol.18
, pp. 2795-2804
-
-
Van Lith, M.1
-
35
-
-
0031573778
-
Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins
-
Lurquin, C. et al. Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins. Genomics 46, 397-408, doi: 10.1006/geno.1997.5052 (1997).
-
(1997)
Genomics
, vol.46
, pp. 397-408
-
-
Lurquin, C.1
-
36
-
-
0342980374
-
Mage-b4, a novel melanoma antigen (MAGE) gene specifically expressed during germ cell differentiation
-
Osterlund, C., Tohonen, V., Forslund, K. O. & Nordqvist, K. Mage-b4, a novel melanoma antigen (MAGE) gene specifically expressed during germ cell differentiation. Cancer research 60, 1054-1061 (2000).
-
(2000)
Cancer Research
, vol.60
, pp. 1054-1061
-
-
Osterlund, C.1
Tohonen, V.2
Forslund, K.O.3
Nordqvist, K.4
-
37
-
-
80755181124
-
Folate and vitamin B12 in idiopathic male infertility
-
Murphy, L. E. et al. Folate and vitamin B12 in idiopathic male infertility. Asian journal of andrology 13, 856-861, doi: 10.1038/aja.2011.96 (2011).
-
(2011)
Asian Journal of Andrology
, vol.13
, pp. 856-861
-
-
Murphy, L.E.1
-
38
-
-
59749096464
-
Clinical practice. Primary ovarian insufficiency
-
Nelson, L. M. Clinical practice. Primary ovarian insufficiency. N Engl J Med 360, 606-614, doi: 10.1056/NEJMcp0808697 (2009).
-
(2009)
N Engl J Med
, vol.360
, pp. 606-614
-
-
Nelson, L.M.1
-
39
-
-
84906674636
-
Identification of novel autoantibodies in type 1 diabetic patients using a high-density protein microarray
-
Koo, B. K. et al. Identification of novel autoantibodies in type 1 diabetic patients using a high-density protein microarray. Diabetes 63, 3022-3032, doi: 10.2337/db13-1566 (2014).
-
(2014)
Diabetes
, vol.63
, pp. 3022-3032
-
-
Koo, B.K.1
-
40
-
-
84920269464
-
Proteomics. Tissue-based map of the human proteome
-
Uhlen, M. et al. Proteomics. Tissue-based map of the human proteome. Science 347, 1260419, doi: 10.1126/science.1260419 (2015).
-
(2015)
Science
, vol.347
, pp. 1260419
-
-
Uhlen, M.1
-
41
-
-
84857969832
-
Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility [corrected]
-
Tokuhiro, K., Ikawa, M., Benham, A. M. & Okabe, M. Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility [corrected]. Proc Natl Acad Sci USA 109, 3850-3855, doi: 10.1073/pnas.1117963109 (2012).
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 3850-3855
-
-
Tokuhiro, K.1
Ikawa, M.2
Benham, A.M.3
Okabe, M.4
-
42
-
-
78149415935
-
Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia
-
Burbelo, P. D. et al. Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia. Blood 116, 4848-4858, doi: 10.1182/blood-2010-05-286161 (2010).
-
(2011)
Blood
, vol.116
, pp. 4848-4858
-
-
Burbelo, P.D.1
-
43
-
-
1542542689
-
Autoantibodies to interferon-gamma in a patient with selective susceptibility to mycobacterial infection and organ-specific autoimmunity
-
Doffinger, R. et al. Autoantibodies to interferon-gamma in a patient with selective susceptibility to mycobacterial infection and organ-specific autoimmunity. Clinical infectious diseases: An official publication of the Infectious Diseases Society of America 38, e10-14, doi: 10.1086/380453 (2004).
-
(2004)
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
, vol.38
, pp. e10-14
-
-
Doffinger, R.1
-
44
-
-
26244449982
-
Autoimmune oophoritis as a mechanism of follicular dysfunction in women with 46,XX spontaneous premature ovarian failure
-
Bakalov, V. K. et al. Autoimmune oophoritis as a mechanism of follicular dysfunction in women with 46,XX spontaneous premature ovarian failure. Fertility and sterility 84, 958-965, doi: 10.1016/j.fertnstert.2005.04.060 (2005).
-
(2005)
Fertility and Sterility
, vol.84
, pp. 958-965
-
-
Bakalov, V.K.1
-
45
-
-
3142665525
-
GOstat: Find statistically overrepresented Gene Ontologies within a group of genes
-
Beissbarth, T. & Speed, T. P. GOstat: find statistically overrepresented Gene Ontologies within a group of genes. Bioinformatics 20, 1464-1465, doi: 10.1093/bioinformatics/bth088 (2004).
-
(2004)
Bioinformatics
, vol.20
, pp. 1464-1465
-
-
Beissbarth, T.1
Speed, T.P.2
|