Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro

Rheumatology

Volumn 49, Issue 11, 2010, Pages 2054-2060

  Abouheif, Mohamed M ^a,b   Nakasa, Tomoyuki ^a   Shibuya, Hayatoshi ^a   Niimoto, Takuya ^a   Kongcharoensombat, Wirat ^a   Ochi, Mitsuo ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b Alexandria University   (Egypt)

Author keywords

Chondrocyte apoptosis; MiRNA 34a; MiRNA 34a specific locked nucleotide analogue; Osteoarthritis

Indexed keywords

COLLAGEN TYPE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MICRORNA; MICRORNA 34A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE DISEASE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE SILENCING; IN VITRO STUDY; MONOLAYER CULTURE; NICK END LABELING; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; RAT; UPREGULATION;

ANIMALS; APOPTOSIS; ARTHRITIS, EXPERIMENTAL; CELLS, CULTURED; CHONDROCYTES; DOWN-REGULATION; MICRORNAS; MODELS, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78649390537     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keq247     Document Type: Article

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