Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

eLife

Volumn 5, Issue JUNE2016, 2016, Pages

  Dejesus, Rowena ^a   Moretti, Francesca ^b   McAllister, Gregory ^a   Wang, Zuncai ^a   Bergman, Phil ^a   Liu, Shanming ^a   Frias, Elizabeth ^a   Alford, John ^a   Reece Hoyes, John S ^a   Lindeman, Alicia ^a   Kelliher, Jennifer ^a   Russ, Carsten ^a   Knehr, Judith ^b   Carbone, Walter ^b   Beibel, Martin ^b   Roma, Guglielmo ^b   Ng, Aylwin ^c   Tallarico, John A ^a   Porter, Jeffery A ^a   Xavier, Ramnik J ^c   Mickanin, Craig ^a   Murphy, Leon O ^a   Hoffman, Gregory R ^a   Nyfeler, Beat ^b   more..

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; PROTEIN P62; PROTEIN SQSTM1; UNCLASSIFIED DRUG; MTOR PROTEIN, HUMAN; PROTEIN; SEQUESTOSOME 1; SQSTM1 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE; UFM1 PROTEIN, HUMAN;

ARTICLE; AUTORADIOGRAPHY; CELL PROLIFERATION; CELL VIABILITY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; EPIFLUORESCENCE MICROSCOPY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC SCREENING; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TRANSCRIPTION REGULATION; UFMYLATION; WESTERN BLOTTING; AUTOPHAGY; CELL LINE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE TARGETING; METABOLISM; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

AUTOPHAGY; CELL LINE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TESTING; HUMANS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; SEQUESTOSOME-1 PROTEIN; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84978790889     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.17290     Document Type: Article

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