Chlorogenic acid suppresses monocrotaline-induced sinusoidal obstruction syndrome: The potential contribution of NFκB, Egr1, Nrf2, MAPKs and PI3K signals

Environmental Toxicology and Pharmacology

Volumn 46, Issue , 2016, Pages 80-89

  Zheng, Zhiyong ^a   Shi, Liang ^a   Sheng, Yuchen ^a   Zhang, Jiaqi ^a   Lu, Bin ^a   Ji, Lili ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Chlorogenic acid; Egr1; Monocrotaline; NF B; Nrf2; SOS

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; BILIRUBIN; CHLOROGENIC ACID; EARLY GROWTH RESPONSE FACTOR 1; GELATINASE B; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MALONALDEHYDE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCROTALINE; MYELOPEROXIDASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; EGR1 PROTEIN, RAT; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NFE2L2 PROTEIN, RAT; TOLL LIKE RECEPTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASCITES; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; EGR1 GENE; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; IL 1BETA GENE; LIVER ASCITES; LIVER HISTOLOGY; LIVER PROTECTION; LIVER VENOOCCLUSIVE DISEASE; MALE; NEUTROPHIL COUNT; NONHUMAN; NUCLEAR FACTOR KAPPA B GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; RETICULOCYTE COUNT; SCANNING ELECTRON MICROSCOPY; SERPINE1 GENE; TF GENE; THROMBOCYTE COUNT; TLR 2 GENE; TLR 3 GENE; TLR 6 GENE; TLR 9 GENE; TNF ALPHA GENE; TRANSCRIPTION INITIATION; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; GENETICS; HEPATIC VENO-OCCLUSIVE DISEASE; METABOLISM; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CHLOROGENIC ACID; DISEASE MODELS, ANIMAL; EARLY GROWTH RESPONSE PROTEIN 1; HEPATIC VENO-OCCLUSIVE DISEASE; MALE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MONOCROTALINE; NF-E2-RELATED FACTOR 2; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84978640753     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2016.07.002     Document Type: Article

References (42)

1. Aljada, A., Ghanim, H., Mohanty, P., Kapur, N., Dandona, P., Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations. J. Clin. Endocrinol. Metab. 87 (2002), 1419–1422.
2. Baeuerle, P.A., Baltimore, D., I Kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science 242 (1988), 540–546.
3. Barclay, K.L., Yeong, M.L., Actinomycin D associated hepatic veno-occlusive disease-a report of 2 cases. Pathology 26 (1994), 257–260.
4. Broering, R., Lu, M., Schlaak, J.F., Role of toll-like receptors in liver health and disease. Clin. Sci. (Lond.) 121 (2011), 415–426.
5. Carreras, E., How I manage sinusoidal obstruction syndrome after haematopoietic cell transplantation. Br. J. Haematol. 168 (2015), 481–491.
6. Chen, Z., Huo, J.R., Yang, L., Zhu, H.Y., Effect of ligustrazine on mice model of hepatic veno-occlusive disease induced by Gynura segetum. J. Gastroenterol. Hepatol. 26 (2011), 1016–1021.
7. Dai, N., Yu, Y.C., Ren, T.H., Wu, J.G., Jiang, Y., Shen, L.G., Zhang, J., Gynura root induces hepatic veno-occlusive disease: a case report and review of the literature. World J. Gastroenterol. 13 (2007), 1628–1631.
8. DeLeve, L.D., McCuskey, R.S., Wang, X.D., Hu, L.P., McCuskey, M.K., Epstein, R.B., Kanel, C.C., Characterization of a reproducible rat model of hepatic veno-occlusive disease. Hepatology 29 (1999), 1779–1991.
9. DeLeve, L.D., Valla, D.C., Garcia-Tsao, G., American Association for the Study Liver Diseases, Vascular disorders of the liver. Hepatology 49 (2009), 1729–1764.
10. Deleve, L.D., Wang, X., Tsai, J., Kanel, G., Strasberg, S., Tokes, Z.A., Sinusoidal obstruction syndrome (veno-occlusive disease) in the rat is prevented by matrix metalloproteinase inhibition. Gastroenterology 125 (2003), 882–890.
11. Doyle, S.L., O'Neill, L.A., Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity. Biochem. Pharmacol. 72 (2006), 1102–1113.
12. Hanumegowda, U.M., Copple, B.L., Shibuya, M., Malle, E., Ganey, P.E., Roth, R.A., Basement membrane and matrix metalloproteinases in monocrotaline- induced liver injury. Toxicol. Sci. 76 (2003), 237–246.
13. Ji, L.L., Jiang, P., Lu, B., Sheng, Y.C., Wang, X., Wang, Z.T., Chlorogenic acid, a dietary polyphenol, protects acetaminophen-induced liver injury and its mechanism. J. Nutr. Biochem. 24 (2013), 1911–1919.
14. Kaleelrahman, M., Eaton, J.D., Leeming, D., Bowyer, K., Taberner, D., Chang, J., Scarffe, J.H., Chopra, R., Role of plasminogen activator inhibitor-1 (PAI-1) levels in the diagnosis of BMT-associated hepatic veno-occlusive disease and monitoring of subsequent therapy with defibrotide (DF). Hematology 8 (2003), 91–95.
15. Kaspar, J.W., Niture, S.K., Jaiswal, A.K., Nrf2:INrf2 (Keap1) signaling in oxidative stress. Free Radic. Biol. Med. 47 (2009), 1304–1309.
16. Keating, G.M., Defibrotide: a review of its use in severe hepatic veno-occlusive disease following haematopoietic stem cell transplantation. Clin. Drug Invest. 34 (2014), 895–904.
17. Koriem, K.M., Soliman, R.E., Chlorogenic and caftaric acids in liver toxicity and oxidative stress induced by methamphetamine. J. Toxicol., 2014, 2014 583494.
18. McGee, J., Patrick, R.S., Wood, C.B., Blumqart, L.H., A case of veno-occlusive disease of the liver in Britain associated with herbal tea consumption. J. Clin. Pathol., 29, 1976 788–194.
19. Mohabbat, O., Younos, M.S., Merzad, A.A., Srivastava, R.N., Sediq, G.G., Aram, G.N., An outbreak of hepatic veno-occlusive disease in north-western Afghanistan. Lancet 2 (1976), 269–271.
20. Nakamura, K., Hatano, E., Narita, M., Miyaqawa-Hayashino, A., Koyama, Y., Naqata, H., Iwaisako, K., Taura, K., Uemoto, S., Sorafenib attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats through suppression of JNK and MMP-9. J. Hepatol. 57 (2012), 1037–1043.
21. Okuno, M., Hatano, E., Nakamura, K., Miyagawa-Hayashino, A., Kasai, Y., Nishio, T., Seo, S., Taura, K., Uemoto, S., Regorafenib suppresses sinusoidal obstruction syndrome in rats. J. Surg. Res. 193 (2015), 693–703.
22. Park, Y.D., Yasui, M., Yoshimoto, T., Chayama, K., Shimono, T., Okamura, T., Inoue, M., Yumura-Yaqi, K., Kawa-Ha, K., Changes in hemostatic parameters in hepatic veno-occlusive disease following bone marrow transplantation. Bone Marrow Transplant. 19 (1997), 915–920.
23. Periasamy, S., Hsu, D.Z., Chen, S.Y., Yang, S.S., Chandrasekaran, V.R., Liu, M.Y., Therapeutic sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats by inhibiting matrix metalloproteinase-9. Cell Biochem. Biophys. 61 (2011), 327–336.
24. Pritchard, M.T., Nagy, L.E., Ethanol-induced liver injury: potential roles for Egr-1. Alcohol. Clin. Exp. Res. 29 (2005), 146S–150S.
25. Pritchard, M.T., Roychowdhury, S., McMullen, M.R., Guo, L., Arteel, G.E., Nagy, L.E., Early growth response-1 contributes to galactosamine/lipopolysaccharide-induced actue liver injury. Am. J. Physiol. Gastrointest. Liver Physiol. 293 (2007), G1124–G1133.
26. Pritchard, M.T., Malinak, R.N., Nagy, L.E., Early growth response (EGR)-1 is required for timely cell-cycle entry and progression in hepatocytes after acute carbon tetrachloride exposure in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 300 (2011), G1124–G1131.
27. Ramaiah, S.K., Jaeschke, H., Role of neutrophils in the pathogenesis of acute inflammatory liver injury. Toxicol. Pathol. 35 (2007), 757–766.
28. Richardson, P.G., Ho, V.T., Cutler, C., Glotzbecker, B., Antin, J.H., Soiffer, R., Hepatic veno-occlusive disease after hematopoietic stem cell transplantation: novel insights to pathogenesis, current status of treatment, and future directions. Biol. Blood Marrow Transplant. 19 (2013), S88–S90.
29. Salat, C., Holler, E., Kolb, H.J., Pihusch, R., Reinhardt, B., Penovici, M., Ledderose, G., Hiller, E., The relevance of plasminogen activator inhibitor 1 (PAI-1) as a marker for the diagnosis of hepatic veno-occlusive disease in patients after bone marrow transplantation. Leuk. Lymphoma 33 (1999), 25–32.
30. Seo, A.H., Kim, H., Sinusoidal obstruction syndrome after oxaliplatin-based chemotherapy. Clin. Mol. Hepatol. 20 (2014), 81–84.
31. Shi, H., Dong, L., Bai, Y., Zhao, J., Zhang, Y., Zhang, L., Chlorogenic acid against carbon tetrachloride-induced liver fibrosis in rats. Eur. J. Pharmacol. 623 (2009), 119–124.
32. Thiel, G., Cibelli, G., Regulation of life and death by the zinc finger transcription factor Egr-1. J. Cell. Physiol. 193 (2002), 287–292.
33. Torres, M., Forman, H.J., Redox signaling and the MAP kinase pathways. Biofactors 17 (2003), 287–296.
34. Troutman, T.D., Bazan, J.F., Pasare, C., Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K. Cell Cycle 11 (2012), 3559–3567.
35. Upadhyay, R., Mohan Rao, L.J., An outlook on chlorogenic acids-occurrence, chemistry, technology, and biological activities. Crit. Rev. Food Sci. Nutr. 53 (2013), 968–984.
36. Wang, J.Y., Gao, H., Tusanqi and hepatic sinusoidal syndrome. J. Dig. Dis. 15 (2014), 105–107.
37. Wang, X., Qi, X., Guo, X., Tusanqi-related sinusoidal obstruction syndrome in China: a systematic review of the Literatures. Medicine (Baltimore), 94, 2015, e942.
38. Willmot, F.C., Robertson, G.W., Senecio disease, or cirrhosis of the liver due to senecio poisoning. Lancet 196 (1920), 848–849.
39. Wu, H.T., He, X.J., Hong, Y.K., Ma, T., Xu, Y.P., Li, H.H., Chemical characterization of lyceum barbarum polysaccharides and its inhibition against liver oxidative injury of high-fat mice. Int. J. Biol. Macromol. 46 (2010), 540–543.
40. Xu, Y., Chen, J., Yu, X., Tao, W., Jiang, F., Yin, Z., Liu, C., Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice. Inflamm. Res. 59 (2010), 871–877.
41. Zeng, S., Dun, H., Ippagunta, N., Rosario, R., Zhang, Q.Y., Lefkowitch, J., Yan, S.F., Schmidt, A.M., Emond, J.C., Receptor for advanced glycation end product (RAGE)- dependent modulation of early growth response-1 in hepatic ischemia/reperfusion injury. J. Hepatol. 50 (2009), 929–936.
42. Zheng, Z.Y., Sheng, Y.C., Lu, B., Ji, L.L., The therapeutic detoxification of chlorogenic acid against acetaminophen-induced liver injury by ameliorating hepatic inflammation. Chem. Biol. Interact. 238 (2015), 93–101.