Sorafenib attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats through suppression of JNK and MMP-9

Journal of Hepatology

Volumn 57, Issue 5, 2012, Pages 1037-1043

  Nakamura, Kojiro ^a,b   Hatano, Etsuro ^a,b   Narita, Masato ^a,b   Miyagawa Hayashino, Aya ^a,b   Koyama, Yukinori ^a,b   Nagata, Hiromitsu ^a,b   Iwaisako, Keiko ^a,b   Taura, Kojiro ^a,b   Uemoto, Shinji ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

JNK; MMP 9; Sinusoidal obstruction syndrome; Sorafenib

Indexed keywords

AMINOTRANSFERASE; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; MONOCROTALINE; SORAFENIB;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; LIVER HISTOLOGY; LIVER RESECTION; LIVER VENOOCCLUSIVE DISEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TOXIC HEPATITIS;

ANIMALS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HEPATECTOMY; HEPATIC VENO-OCCLUSIVE DISEASE; LIVER; MALE; MAP KINASE KINASE 4; MATRIX METALLOPROTEINASE 9; MONOCROTALINE; NIACINAMIDE; PHENYLUREA COMPOUNDS; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84867575484     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.07.004     Document Type: Article

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