-
1
-
-
36649034681
-
The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel
-
Ahmed AA, Mills AD, Ibrahim AE, Temple J, Blenkiron C, Vias M, Massie CE, Iyer NG, McGeoch A, Crawford R, Nicke B, Downward J, Swanton C, Bell SD, Earl HM, Laskey RA, Caldas C, Brenton JD (2007) The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel. Cancer Cell 12(6): 514-527.
-
(2007)
Cancer Cell
, vol.12
, Issue.6
, pp. 514-527
-
-
Ahmed, A.A.1
Mills, A.D.2
Ibrahim, A.E.3
Temple, J.4
Blenkiron, C.5
Vias, M.6
Massie, C.E.7
Iyer, N.G.8
McGeoch, A.9
Crawford, R.10
Nicke, B.11
Downward, J.12
Swanton, C.13
Bell, S.D.14
Earl, H.M.15
Laskey, R.A.16
Caldas, C.17
Brenton, J.D.18
-
2
-
-
0034667390
-
Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance
-
Allen JD, Brinkhuis RF, van Deemter L, Wijnholds J, Schinkel AH (2000) Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance. Cancer Res 60(20): 5761-5766.
-
(2000)
Cancer Res
, vol.60
, Issue.20
, pp. 5761-5766
-
-
Allen, J.D.1
Brinkhuis, R.F.2
Van Deemter, L.3
Wijnholds, J.4
Schinkel, A.H.5
-
3
-
-
0028296566
-
Expression of multidrug resistance gene and localization of P-glycoprotein in human primary ovarian cancer
-
Arao S, Suwa H, Mandai M, Tashiro H, Miyazaki K, Okamura H, Nomura H, Hiai H, Fukumoto M (1994) Expression of multidrug resistance gene and localization of P-glycoprotein in human primary ovarian cancer. Cancer Res 54(5): 1355-1359.
-
(1994)
Cancer Res
, vol.54
, Issue.5
, pp. 1355-1359
-
-
Arao, S.1
Suwa, H.2
Mandai, M.3
Tashiro, H.4
Miyazaki, K.5
Okamura, H.6
Nomura, H.7
Hiai, H.8
Fukumoto, M.9
-
4
-
-
77955039099
-
Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proof-of-concept trial
-
Audeh MW, Carmichael J, Penson RT, Friedlander M, Powell B, Bell-McGuinn KM, Scott C, Weitzel JN, Oaknin A, Loman N, Lu K, Schmutzler RK, Matulonis U, Wickens M, Tutt A (2010) Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet 376(9737): 245-251.
-
(2010)
Lancet
, vol.376
, Issue.9737
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
Friedlander, M.4
Powell, B.5
Bell-McGuinn, K.M.6
Scott, C.7
Weitzel, J.N.8
Oaknin, A.9
Loman, N.10
Lu, K.11
Schmutzler, R.K.12
Matulonis, U.13
Wickens, M.14
Tutt, A.15
-
5
-
-
84940062758
-
Drug transporter-mediated protection of cancer stem cells from ionophore antibiotics
-
Boesch M, Zeimet AG, Rumpold H, Gastl G, Sopper S, Wolf D (2015) Drug transporter-mediated protection of cancer stem cells from ionophore antibiotics. Stem Cells Transl Med 4(9): 1028-1032.
-
(2015)
Stem Cells Transl Med
, vol.4
, Issue.9
, pp. 1028-1032
-
-
Boesch, M.1
Zeimet, A.G.2
Rumpold, H.3
Gastl, G.4
Sopper, S.5
Wolf, D.6
-
6
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, Kyle S, Meuth M, Curtin NJ, Helleday T (2005) Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 434(7035): 913-917.
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
Kyle, S.7
Meuth, M.8
Curtin, N.J.9
Helleday, T.10
-
7
-
-
60549112572
-
Association of the ABCB1 gene polymorphisms 2677G4T/A and 3435C4T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients
-
Chang H, Rha SY, Jeung HC, Im CK, Ahn JB, KwonWS, Yoo NC, Roh JK, Chung HC (2009) Association of the ABCB1 gene polymorphisms 2677G4T/A and 3435C4T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients. Ann Oncol 20(2): 272-277.
-
(2009)
Ann Oncol
, vol.20
, Issue.2
, pp. 272-277
-
-
Chang, H.1
Rha, S.Y.2
Jeung, H.C.3
Im, C.K.4
Ahn, J.B.5
Kwon, W.S.6
Yoo, N.C.7
Roh, J.K.8
Chung, H.C.9
-
8
-
-
84892805503
-
7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors
-
Cincinelli R, Musso L, Merlini L, Giannini G, Vesci L, Milazzo FM, Carenini N, Perego P, Penco S, Artali R, Zunino F, Pisano C, Dallavalle S (2014) 7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors. Bioorg Med Chem 22(3): 1089-1103.
-
(2014)
Bioorg Med Chem
, vol.22
, Issue.3
, pp. 1089-1103
-
-
Cincinelli, R.1
Musso, L.2
Merlini, L.3
Giannini, G.4
Vesci, L.5
Milazzo, F.M.6
Carenini, N.7
Perego, P.8
Penco, S.9
Artali, R.10
Zunino, F.11
Pisano, C.12
Dallavalle, S.13
-
9
-
-
0023234519
-
Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein
-
Cornwell MM, Pastan I, Gottesman MM (1987) Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein. J Biol Chem 262(5): 2166-2170.
-
(1987)
J Biol Chem
, vol.262
, Issue.5
, pp. 2166-2170
-
-
Cornwell, M.M.1
Pastan, I.2
Gottesman, M.M.3
-
10
-
-
84856509572
-
Phase i study to assess the safety and tolerability of olaparib in combination with bevacizumab in patients with advanced solid tumours
-
Dean E, Middleton MR, Pwint T, Swaisland H, Carmichael J, Goodege-Kunwar P, Ranson M (2012) Phase I study to assess the safety and tolerability of olaparib in combination with bevacizumab in patients with advanced solid tumours. Br J Cancer 106(3): 468-474.
-
(2012)
Br J Cancer
, vol.106
, Issue.3
, pp. 468-474
-
-
Dean, E.1
Middleton, M.R.2
Pwint, T.3
Swaisland, H.4
Carmichael, J.5
Goodege-Kunwar, P.6
Ranson, M.7
-
11
-
-
1542359573
-
UV irradiation inhibits ABC transporters via generation of ADPribose by concerted action of poly(ADP-ribose) polymerase-1 and glycohydrolase
-
Dumitriu IE, Voll RE, Kolowos W, GaiplUS, Heyder P, Kalden JR, HerrmannM (2004) UV irradiation inhibits ABC transporters via generation of ADPribose by concerted action of poly(ADP-ribose) polymerase-1 and glycohydrolase. Cell Death Differ 11(3): 314-320.
-
(2004)
Cell Death Differ
, vol.11
, Issue.3
, pp. 314-320
-
-
Dumitriu, I.E.1
Voll, R.E.2
Kolowos, W.3
Gaipl, U.S.4
Heyder, P.5
Kalden, J.R.6
Herrmann, M.7
-
12
-
-
84938587076
-
Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) restrict oral availability and brain accumulation of the PARP inhibitor rucaparib (AG-014699)
-
Durmus S, Sparidans RW, van Esch A, Wagenaar E, Beijnen JH, Schinkel AH (2015) Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) restrict oral availability and brain accumulation of the PARP inhibitor rucaparib (AG-014699). Pharm Res 32(1): 37-46.
-
(2015)
Pharm Res
, vol.32
, Issue.1
, pp. 37-46
-
-
Durmus, S.1
Sparidans, R.W.2
Van Esch, A.3
Wagenaar, E.4
Beijnen, J.H.5
Schinkel, A.H.6
-
13
-
-
39849097680
-
Resistance to therapy caused by intragenic deletion in BRCA2
-
Edwards SL, Brough R, Lord CJ, Natrajan R, Vatcheva R, Levine DA, Boyd J, Reis-Filho JS, Ashworth A (2008) Resistance to therapy caused by intragenic deletion in BRCA2. Nature 451(7182): 1111-1115.
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1111-1115
-
-
Edwards, S.L.1
Brough, R.2
Lord, C.J.3
Natrajan, R.4
Vatcheva, R.5
Levine, D.A.6
Boyd, J.7
Reis-Filho, J.S.8
Ashworth, A.9
-
14
-
-
0020055650
-
Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells
-
Eva A, Robbins KC, Andersen PR, Srinivasan A, Tronick SR, Reddy EP, Ellmore NW, Galen AT, Lautenberger JA, Papas TS, Westin EH, Wong-Staal F, Gallo RC, Aaronson SA (1982) Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells. Nature 295(5845): 116-119.
-
(1982)
Nature
, vol.295
, Issue.5845
, pp. 116-119
-
-
Eva, A.1
Robbins, K.C.2
Andersen, P.R.3
Srinivasan, A.4
Tronick, S.R.5
Reddy, E.P.6
Ellmore, N.W.7
Galen, A.T.8
Lautenberger, J.A.9
Papas, T.S.10
Westin, E.H.11
Wong-Staal, F.12
Gallo, R.C.13
Aaronson, S.A.14
-
15
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A (2005) Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434(7035): 917-921.
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
Martin, N.M.11
Jackson, S.P.12
Smith, G.C.13
Ashworth, A.14
-
16
-
-
0042132423
-
Expression of a multidrug-resistance gene in human tumors and tissues
-
Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MM, Pastan I (1987) Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 84(1): 265-269.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, Issue.1
, pp. 265-269
-
-
Fojo, A.T.1
Ueda, K.2
Slamon, D.J.3
Poplack, D.G.4
Gottesman, M.M.5
Pastan, I.6
-
17
-
-
79251514312
-
Influence of Cremophor EL and genetic polymorphisms on the pharmacokinetics of paclitaxel and its metabolites using a mechanism-based model
-
Fransson MN, Green H, Litton JE, Friberg LE (2011) Influence of Cremophor EL and genetic polymorphisms on the pharmacokinetics of paclitaxel and its metabolites using a mechanism-based model. Drug Metab Dispos 39(2): 247-255.
-
(2011)
Drug Metab Dispos
, vol.39
, Issue.2
, pp. 247-255
-
-
Fransson, M.N.1
Green, H.2
Litton, J.E.3
Friberg, L.E.4
-
18
-
-
32944468151
-
Mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy
-
Green H, Soderkvist P, Rosenberg P, Horvath G, Peterson C (2006) mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy. Clin Cancer Res 12(3 Pt 1): 854-859.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.3
, pp. 854-859
-
-
Green, H.1
Soderkvist, P.2
Rosenberg, P.3
Horvath, G.4
Peterson, C.5
-
19
-
-
0026781491
-
Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas
-
Holzmayer TA, Hilsenbeck S, Von Hoff DD, Roninson IB (1992) Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas. J Natl Cancer Inst 84(19): 1486-1491.
-
(1992)
J Natl Cancer Inst
, vol.84
, Issue.19
, pp. 1486-1491
-
-
Holzmayer, T.A.1
Hilsenbeck, S.2
Von Hoff, D.D.3
Roninson, I.B.4
-
20
-
-
0027524642
-
In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative
-
Hyafil F, Vergely C, Du Vignaud P, Grand-Perret T (1993) In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative. Cancer Res 53(19): 4595-4602.
-
(1993)
Cancer Res
, vol.53
, Issue.19
, pp. 4595-4602
-
-
Hyafil, F.1
Vergely, C.2
Du Vignaud, P.3
Grand-Perret, T.4
-
21
-
-
84926368806
-
Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control
-
Ingemarsdotter CK, Tookman LA, Browne A, Pirlo K, Cutts R, Chelela C, Khurrum KF, Leung EY, Dowson S, Webber L, Khan I, Ennis D, Syed N, Crook TR, Brenton JD, Lockley M, McNeish IA (2015) Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control. Mol Oncol 9(4): 791-805.
-
(2015)
Mol Oncol
, vol.9
, Issue.4
, pp. 791-805
-
-
Ingemarsdotter, C.K.1
Tookman, L.A.2
Browne, A.3
Pirlo, K.4
Cutts, R.5
Chelela, C.6
Khurrum, K.F.7
Leung, E.Y.8
Dowson, S.9
Webber, L.10
Khan, I.11
Ennis, D.12
Syed, N.13
Crook, T.R.14
Brenton, J.D.15
Lockley, M.16
McNeish, I.A.17
-
22
-
-
84872837247
-
Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors
-
Jaspers JE, Kersbergen A, Boon U, Sol W, van Deemter L, Zander SA, Drost R, Wientjens E, Ji J, Aly A, Doroshow JH, Cranston A, Martin NM, Lau A, O'Connor MJ, Ganesan S, Borst P, Jonkers J, Rottenberg S (2013) Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors. Cancer Discov 3(1): 68-81.
-
(2013)
Cancer Discov
, vol.3
, Issue.1
, pp. 68-81
-
-
Jaspers, J.E.1
Kersbergen, A.2
Boon, U.3
Sol, W.4
Van Deemter, L.5
Zander, S.A.6
Drost, R.7
Wientjens, E.8
Ji, J.9
Aly, A.10
Doroshow, J.H.11
Cranston, A.12
Martin, N.M.13
Lau, A.14
O'Connor, M.J.15
Ganesan, S.16
Borst, P.17
Jonkers, J.18
Rottenberg, S.19
-
23
-
-
84923119094
-
BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance
-
Jaspers JE, Sol W, Kersbergen A, Schlicker A, Guyader C, Xu G, Wessels L, Borst P, Jonkers J, Rottenberg S (2015) BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance. Cancer Res 75(4): 732-741.
-
(2015)
Cancer Res
, vol.75
, Issue.4
, pp. 732-741
-
-
Jaspers, J.E.1
Sol, W.2
Kersbergen, A.3
Schlicker, A.4
Guyader, C.5
Xu, G.6
Wessels, L.7
Borst, P.8
Jonkers, J.9
Rottenberg, S.10
-
24
-
-
84885318807
-
ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: A comprehensive analysis from the Ovarian Cancer Association Consortium and the Cancer Genome Atlas
-
Australian Ovarian Cancer Study GroupGoode EL
-
Johnatty SE, Beesley J, Gao B, Chen X, Lu Y, LawMH, HendersonMJ, RussellAJ, Hedditch EL, Emmanuel C, Fereday S, Webb PM. Australian Ovarian Cancer Study GroupGoode EL, Vierkant RA, Fridley BL, Cunningham JM, Fasching PA, Beckmann MW, Ekici AB, Hogdall E, Kjaer SK, Jensen A, Hogdall C, Brown R, Paul J, Lambrechts S, Despierre E, Vergote I, Lester J, Karlan BY, Heitz F, du Bois A, Harter P, Schwaab I, Bean Y, Pejovic T, Levine DA, Goodman MT, Camey ME, Thompson PJ, Lurie G, Shildkraut J, Berchuck A, Terry KL, Cramer DW, Norris MD, Haber M, MacGregor S, de Fazio A, Chenevix-Trench G (2013) ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas. Gynecol Oncol 131(1): 8-14.
-
(2013)
Gynecol Oncol
, vol.131
, Issue.1
, pp. 8-14
-
-
Johnatty, S.E.1
Beesley, J.2
Gao, B.3
Chen, X.4
Lu, Y.5
Law, M.H.6
Henderson, M.J.7
Russell, A.J.8
Hedditch, E.L.9
Emmanuel, C.10
Fereday, S.11
Vierkant, R.A.12
Fridley, B.L.13
Cunningham, J.M.14
Fasching, P.A.15
Beckmann, M.W.16
Ekici, A.B.17
Hogdall, E.18
Kjaer, S.K.19
Jensen, A.20
Hogdall, C.21
Brown, R.22
Paul, J.23
Lambrechts, S.24
Despierre, E.25
Vergote, I.26
Lester, J.27
Karlan, B.Y.28
Heitz, F.29
Du Bois, A.30
Harter, P.31
Schwaab, I.32
Bean, Y.33
Pejovic, T.34
Levine, D.A.35
Goodman, M.T.36
Camey, M.E.37
Thompson, P.J.38
Lurie, G.39
Shildkraut, J.40
Berchuck, A.41
Terry, K.L.42
Cramer, D.W.43
Norris, M.D.44
Haber, M.45
MacGregor, S.46
De Fazio, A.47
Chenevix-Trench, G.48
more..
-
25
-
-
84885770237
-
Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance
-
Johnson N, Johnson SF, Yao W, Li YC, Choi YE, Bernhardy AJ, Wang Y, Capelletti M, Sarosiek KA, Moreau LA, Chowdhury D, Wickramanayake A, Harrell MI, Liu JF, D'Andrea AD, Miron A, Swisher EM, Shapiro GI (2013) Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance. Proc Natl Acad Sci USA 110(42): 17041-17046.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.42
, pp. 17041-17046
-
-
Johnson, N.1
Johnson, S.F.2
Yao, W.3
Li, Y.C.4
Choi, Y.E.5
Bernhardy, A.J.6
Wang, Y.7
Capelletti, M.8
Sarosiek, K.A.9
Moreau, L.A.10
Chowdhury, D.11
Wickramanayake, A.12
Harrell, M.I.13
Liu, J.F.14
D'Andrea, A.D.15
Miron, A.16
Swisher, E.M.17
Shapiro, G.I.18
-
26
-
-
84922223032
-
The modulation of ABC transporter-mediated multidrug resistance in cancer: A review of the past decade
-
Kathawala RJ, Gupta P, Ashby Jr CR, Chen ZS (2015) The modulation of ABC transporter-mediated multidrug resistance in cancer: a review of the past decade. Drug Resist Updat 18: 1-17.
-
(2015)
Drug Resist Updat
, vol.18
, pp. 1-17
-
-
Kathawala, R.J.1
Gupta, P.2
Ashby, C.R.3
Chen, Z.S.4
-
27
-
-
79551698205
-
A pharmacodynamic study of docetaxel in combination with the P-glycoprotein antagonist tariquidar (XR9576) in patients with lung, ovarian, and cervical cancer
-
Kelly RJ, Draper D, Chen CC, Robey RW, Figg WD, Piekarz RL, Chen X, Gardner ER, Balis FM, Venkatesan AM, Steinberg SM, Fojo T, Bates SE (2011) A pharmacodynamic study of docetaxel in combination with the P-glycoprotein antagonist tariquidar (XR9576) in patients with lung, ovarian, and cervical cancer. Clin Cancer Res 17(3): 569-580.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.3
, pp. 569-580
-
-
Kelly, R.J.1
Draper, D.2
Chen, C.C.3
Robey, R.W.4
Figg, W.D.5
Piekarz, R.L.6
Chen, X.7
Gardner, E.R.8
Balis, F.M.9
Venkatesan, A.M.10
Steinberg, S.M.11
Fojo, T.12
Bates, S.E.13
-
28
-
-
84860139048
-
A pharmacodynamic study of the P-glycoprotein antagonist CBT-1(R) in combination with paclitaxel in solid tumors
-
Kelly RJ, Robey RW, Chen CC, Draper D, Luchenko V, Barnett D, Oldham RK, Caluag Z, Frye AR, Steinberg SM, Fojo T, Bates SE (2012) A pharmacodynamic study of the P-glycoprotein antagonist CBT-1(R) in combination with paclitaxel in solid tumors. Oncologist 17(4): 512.
-
(2012)
Oncologist
, vol.17
, Issue.4
, pp. 512
-
-
Kelly, R.J.1
Robey, R.W.2
Chen, C.C.3
Draper, D.4
Luchenko, V.5
Barnett, D.6
Oldham, R.K.7
Caluag, Z.8
Frye, A.R.9
Steinberg, S.M.10
Fojo, T.11
Bates, S.E.12
-
29
-
-
63749117523
-
Genetic polymorphisms affecting clinical outcomes in epithelial ovarian cancer patients treated with taxanes and platinum compounds: A Korean population-based study
-
Kim HS, Kim MK, Chung HH, Kim JW, Park NH, Song YS, Kang SB (2009) Genetic polymorphisms affecting clinical outcomes in epithelial ovarian cancer patients treated with taxanes and platinum compounds: a Korean population-based study. Gynecol Oncol 113(2): 264-269.
-
(2009)
Gynecol Oncol
, vol.113
, Issue.2
, pp. 264-269
-
-
Kim, H.S.1
Kim, M.K.2
Chung, H.H.3
Kim, J.W.4
Park, N.H.5
Song, Y.S.6
Kang, S.B.7
-
30
-
-
0034109492
-
Correlation of drug response with the ATP tumorchemosensitivity assay in primary FIGO stage III ovarian cancer
-
Konecny G, Crohns C, Pegram M, Felber M, Lude S, Kurbacher C, Cree IA, Hepp H, Untch M (2000) Correlation of drug response with the ATP tumorchemosensitivity assay in primary FIGO stage III ovarian cancer. Gynecol Oncol 77(2): 258-263.
-
(2000)
Gynecol Oncol
, vol.77
, Issue.2
, pp. 258-263
-
-
Konecny, G.1
Crohns, C.2
Pegram, M.3
Felber, M.4
Lude, S.5
Kurbacher, C.6
Cree, I.A.7
Hepp, H.8
Untch, M.9
-
31
-
-
84355161452
-
ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells
-
Krech T, Scheuerer E, Geffers R, Kreipe H, Lehmann U, Christgen M (2012) ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells. Cancer Lett 315(2): 153-160.
-
(2012)
Cancer Lett
, vol.315
, Issue.2
, pp. 153-160
-
-
Krech, T.1
Scheuerer, E.2
Geffers, R.3
Kreipe, H.4
Lehmann, U.5
Christgen, M.6
-
32
-
-
0023816378
-
Characterization and properties of nine human ovarian adenocarcinoma cell lines
-
Langdon SP, Lawrie SS, Hay FG, Hawkes MM, McDonald A, Hayward IP, Schol DJ, Hilgers J, Leonard RC, Smyth JF (1988) Characterization and properties of nine human ovarian adenocarcinoma cell lines. Cancer Res 48(21): 6166-6172.
-
(1988)
Cancer Res
, vol.48
, Issue.21
, pp. 6166-6172
-
-
Langdon, S.P.1
Lawrie, S.S.2
Hay, F.G.3
Hawkes, M.M.4
McDonald, A.5
Hayward, I.P.6
Schol, D.J.7
Hilgers, J.8
Leonard, R.C.9
Smyth, J.F.10
-
33
-
-
84901277295
-
PARP Inhibitors as P-glyoprotein Substrates
-
Lawlor D, Martin P, Busschots S, Thery J, O'Leary JJ, Hennessy BT, Stordal B (2014) PARP Inhibitors as P-glyoprotein Substrates. J Pharm Sci 103(6): 1913-1920.
-
(2014)
J Pharm Sci
, vol.103
, Issue.6
, pp. 1913-1920
-
-
Lawlor, D.1
Martin, P.2
Busschots, S.3
Thery, J.4
O'Leary, J.J.5
Hennessy, B.T.6
Stordal, B.7
-
34
-
-
84934282871
-
CECs and IL-8 have prognostic and predictive utility in patients with recurrent platinum-sensitive ovarian cancer: Biomarker correlates from the randomized phase-2 trial of olaparib and cediranib compared with olaparib in recurrent platinum-sensitive ovarian cancer
-
Lee JM, Trepel JB, Choyke P, Cao L, Sissung T, Houston N, Yu M, Figg WD, Turkbey IB, Steinberg SM, Lee MJ, Ivy SP, Liu JF, Matulonis UA, Kohn EC (2015) CECs and IL-8 have prognostic and predictive utility in patients with recurrent platinum-sensitive ovarian cancer: biomarker correlates from the randomized phase-2 trial of olaparib and cediranib compared with olaparib in recurrent platinum-sensitive ovarian cancer. Front Oncol 5: 123.
-
(2015)
Front Oncol
, vol.5
, pp. 123
-
-
Lee, J.M.1
Trepel, J.B.2
Choyke, P.3
Cao, L.4
Sissung, T.5
Houston, N.6
Yu, M.7
Figg, W.D.8
Turkbey, I.B.9
Steinberg, S.M.10
Lee, M.J.11
Ivy, S.P.12
Liu, J.F.13
Matulonis, U.A.14
Kohn, E.C.15
-
35
-
-
84908134454
-
Combination cediranib and olaparib versus olaparib alone for women with recurrent platinum-sensitive ovarian cancer: A randomised phase 2 study
-
Liu JF, Barry WT, Birrer M, Lee JM, Buckanovich RJ, Fleming GF, Rimel B, Buss MK, Nattam S, Hurteau J, Luo W, Quy P, Whalen C, Obermayer L, Lee H, Winer EP, Kohn EC, Ivy SP, Matulonis UA (2014) Combination cediranib and olaparib versus olaparib alone for women with recurrent platinum-sensitive ovarian cancer: a randomised phase 2 study. Lancet Oncol 15(11): 1207-1214.
-
(2014)
Lancet Oncol
, vol.15
, Issue.11
, pp. 1207-1214
-
-
Liu, J.F.1
Barry, W.T.2
Birrer, M.3
Lee, J.M.4
Buckanovich, R.J.5
Fleming, G.F.6
Rimel, B.7
Buss, M.K.8
Nattam, S.9
Hurteau, J.10
Luo, W.11
Quy, P.12
Whalen, C.13
Obermayer, L.14
Lee, H.15
Winer, E.P.16
Kohn, E.C.17
Ivy, S.P.18
Matulonis, U.A.19
-
36
-
-
77954687352
-
MDR1 C2005T polymorphism changes substrate specificity
-
Liu L, Fan L, Peng X, Hu D, Zhou H (2010) MDR1 C2005T polymorphism changes substrate specificity. Cancer Chemother Pharmacol 66(3): 617-623.
-
(2010)
Cancer Chemother Pharmacol
, vol.66
, Issue.3
, pp. 617-623
-
-
Liu, L.1
Fan, L.2
Peng, X.3
Hu, D.4
Zhou, H.5
-
37
-
-
35648997048
-
Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: The Scottish Randomised Trial in Ovarian Cancer
-
Marsh S, Paul J, King CR, Gifford G, McLeod HL, Brown R (2007) Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian Cancer. J Clin Oncol 25(29): 4528-4535.
-
(2007)
J Clin Oncol
, vol.25
, Issue.29
, pp. 4528-4535
-
-
Marsh, S.1
Paul, J.2
King, C.R.3
Gifford, G.4
McLeod, H.L.5
Brown, R.6
-
38
-
-
35448968240
-
RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors
-
Martin RW, Orelli BJ, Yamazoe M, Minn AJ, Takeda S, Bishop DK (2007) RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors. Cancer Res 67(20): 9658-9665.
-
(2007)
Cancer Res
, vol.67
, Issue.20
, pp. 9658-9665
-
-
Martin, R.W.1
Orelli, B.J.2
Yamazoe, M.3
Minn, A.J.4
Takeda, S.5
Bishop, D.K.6
-
39
-
-
3242663647
-
RNA expression of MDR1/ P-glycoprotein, DNA-topoisomerase I, and MRP2 in ovarian carcinoma patients: Correlation with chemotherapeutic response
-
Materna V, Pleger J, Hoffmann U, Lage H (2004) RNA expression of MDR1/ P-glycoprotein, DNA-topoisomerase I, and MRP2 in ovarian carcinoma patients: correlation with chemotherapeutic response. Gynecol Oncol 94(1): 152-160.
-
(2004)
Gynecol Oncol
, vol.94
, Issue.1
, pp. 152-160
-
-
Materna, V.1
Pleger, J.2
Hoffmann, U.3
Lage, H.4
-
40
-
-
84900459013
-
Genomic profile of ovarian carcinomas
-
Micci F, Haugom L, Abeler VM, Davidson B, Trope CG, Heim S (2014) Genomic profile of ovarian carcinomas. BMC Cancer 14: 315.
-
(2014)
BMC Cancer
, vol.14
, pp. 315
-
-
Micci, F.1
Haugom, L.2
Abeler, V.M.3
Davidson, B.4
Trope, C.G.5
Heim, S.6
-
41
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65(1-2): 55-63.
-
(1983)
J Immunol Methods
, vol.65
, Issue.1-2
, pp. 55-63
-
-
Mosmann, T.1
-
42
-
-
80051642095
-
Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas
-
Norquist B, Wurz KA, Pennil CC, Garcia R, Gross J, Sakai W, Karlan BY, Taniguchi T, Swisher EM (2011) Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas. J Clin Oncol 29(22): 3008-3015.
-
(2011)
J Clin Oncol
, vol.29
, Issue.22
, pp. 3008-3015
-
-
Norquist, B.1
Wurz, K.A.2
Pennil, C.C.3
Garcia, R.4
Gross, J.5
Sakai, W.6
Karlan, B.Y.7
Taniguchi, T.8
Swisher, E.M.9
-
43
-
-
84924760015
-
Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: A randomised phase 2 trial
-
Oza AM, Cibula D, Benzaquen AO, Poole C, Mathijssen RH, Sonke GS, Colombo N, Spacek J, Vuylsteke P, Hirte H, Mahner S, Plante M, Schmalfeldt B, Mackay H, Rowbottom J, Lowe ES, Dougherty B, Barrett JC, Friedlander M (2015) Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial. Lancet Oncol 16(1): 87-97.
-
(2015)
Lancet Oncol
, vol.16
, Issue.1
, pp. 87-97
-
-
Oza, A.M.1
Cibula, D.2
Benzaquen, A.O.3
Poole, C.4
Mathijssen, R.H.5
Sonke, G.S.6
Colombo, N.7
Spacek, J.8
Vuylsteke, P.9
Hirte, H.10
Mahner, S.11
Plante, M.12
Schmalfeldt, B.13
Mackay, H.14
Rowbottom, J.15
Lowe, E.S.16
Dougherty, B.17
Barrett, J.C.18
Friedlander, M.19
-
44
-
-
0023237840
-
Verapamil and adriamycin in the treatment of drugresistant ovarian cancer patients
-
Ozols RF, Cunnion RE, Klecker Jr RW, Hamilton TC, Ostchega Y, Parrillo JE, Young RC (1987) Verapamil and adriamycin in the treatment of drugresistant ovarian cancer patients. J Clin Oncol 5(4): 641-647.
-
(1987)
J Clin Oncol
, vol.5
, Issue.4
, pp. 641-647
-
-
Ozols, R.F.1
Cunnion, R.E.2
Klecker, R.W.3
Hamilton, T.C.4
Ostchega, Y.5
Parrillo, J.E.6
Young, R.C.7
-
45
-
-
0031581815
-
Acquisition of taxol resistance via P-glycoprotein-and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cells
-
Parekh H, Wiesen K, Simpkins H (1997) Acquisition of taxol resistance via P-glycoprotein-and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cells. Biochem Pharmacol 53(4): 461-470.
-
(1997)
Biochem Pharmacol
, vol.53
, Issue.4
, pp. 461-470
-
-
Parekh, H.1
Wiesen, K.2
Simpkins, H.3
-
46
-
-
3142615822
-
Analysis of cytogenetic alterations in stage III serous ovarian adenocarcinoma reveals a heterogeneous group regarding survival, surgical outcome, and substage
-
Partheen K, Levan K, Osterberg L, Helou K, Horvath G (2004) Analysis of cytogenetic alterations in stage III serous ovarian adenocarcinoma reveals a heterogeneous group regarding survival, surgical outcome, and substage. Genes Chromosomes Cancer 40(4): 342-348.
-
(2004)
Genes Chromosomes Cancer
, vol.40
, Issue.4
, pp. 342-348
-
-
Partheen, K.1
Levan, K.2
Osterberg, L.3
Helou, K.4
Horvath, G.5
-
47
-
-
84930638395
-
Whole-genome characterization of chemoresistant ovarian cancer
-
Australian Ovarian Cancer Study GroupHamilton A
-
Patch AM, Christie EL, Etemadmoghadam D, Garsed DW, George J, Fereday S, Nones K, Cowin P, Alsop K, Bailey PJ, Kassahn KS, Newell F, Quinn MC, Kazakoff S, Quek K, Wilhelm-Benartzi C, Curry E, Leong HS. Australian Ovarian Cancer Study GroupHamilton A, Mileshkin L, Au-Yeung G, Kennedy C, Hung J, Chiew YE, Harnett P, Friedlander M, Quinn M, Pyman J, Cordner S, O'Brien P, Leditschke J, Young G, Strachan K, Waring P, Azar W, Mitchell C, Traficante N, Hendley J, Thorne H, Shackleton M, Miller DK, Arnau GM, Tothill RW, Holloway TP, Semple T, Harliwong I, Nourse C, Nourbakhsh E, Manning S, Idrisoglu S, Bruxner TJ, Christ AN, Poudel B, Holmes O, Anderson M, Leonard C, Lonie A, Hall N, Wood S, Taylor DF, Xu Q, Fink JL, Waddell N, Drapkin R, Stronach E, Gabra H, Brown R, Jewell A, Nagaraj SH, Markham E, Wilson PJ, Ellul J, McNally O, Doyle MA, Vedururu R, Stewart C, Lengyel E, Pearson JV, Waddell N, de Fazio A, Grimmond SM, Bowtell DD (2015) Whole-genome characterization of chemoresistant ovarian cancer. Nature 521(7553): 489-494.
-
(2015)
Nature
, vol.521
, Issue.7553
, pp. 489-494
-
-
Patch, A.M.1
Christie, E.L.2
Etemadmoghadam, D.3
Garsed, D.W.4
George, J.5
Fereday, S.6
Nones, K.7
Cowin, P.8
Alsop, K.9
Bailey, P.J.10
Kassahn, K.S.11
Newell, F.12
Quinn, M.C.13
Kazakoff, S.14
Quek, K.15
Wilhelm-Benartzi, C.16
Curry, E.17
Leong, H.S.18
Mileshkin, L.19
Au-Yeung, G.20
Kennedy, C.21
Hung, J.22
Chiew, Y.E.23
Harnett, P.24
Friedlander, M.25
Quinn, M.26
Pyman, J.27
Cordner, S.28
O'Brien, P.29
Leditschke, J.30
Young, G.31
Strachan, K.32
Waring, P.33
Azar, W.34
Mitchell, C.35
Traficante, N.36
Hendley, J.37
Thorne, H.38
Shackleton, M.39
Miller, D.K.40
Arnau, G.M.41
Tothill, R.W.42
Holloway, T.P.43
Semple, T.44
Harliwong, I.45
Nourse, C.46
Nourbakhsh, E.47
Manning, S.48
Idrisoglu, S.49
Bruxner, T.J.50
Christ, A.N.51
Poudel, B.52
Holmes, O.53
Anderson, M.54
Leonard, C.55
Lonie, A.56
Hall, N.57
Wood, S.58
Taylor, D.F.59
Xu, Q.60
Fink, J.L.61
Waddell, N.62
Drapkin, R.63
Stronach, E.64
Gabra, H.65
Brown, R.66
Jewell, A.67
Nagaraj, S.H.68
Markham, E.69
Wilson, P.J.70
Ellul, J.71
McNally, O.72
Doyle, M.A.73
Vedururu, R.74
Stewart, C.75
Lengyel, E.76
Pearson, J.V.77
Waddell, N.78
De Fazio, A.79
Grimmond, S.M.80
Bowtell, D.D.81
more..
-
48
-
-
79952747328
-
Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells
-
Patel AG, Sarkaria JN, Kaufmann SH (2011) Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells. Proc Natl Acad Sci USA 108(8): 3406-3411.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.8
, pp. 3406-3411
-
-
Patel, A.G.1
Sarkaria, J.N.2
Kaufmann, S.H.3
-
49
-
-
1842477895
-
Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: A study in serial samples
-
Penson RT, Oliva E, Skates SJ, Glyptis T, Fuller Jr AF, Goodman A, Seiden MV (2004) Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples. Gynecol Oncol 93(1): 98-106.
-
(2004)
Gynecol Oncol
, vol.93
, Issue.1
, pp. 98-106
-
-
Penson, R.T.1
Oliva, E.2
Skates, S.J.3
Glyptis, T.4
Fuller, A.F.5
Goodman, A.6
Seiden, M.V.7
-
50
-
-
55949092708
-
High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
-
Rottenberg S, Jaspers JE, Kersbergen A, van der Burg E, Nygren AO, Zander SA, Derksen PW, de Bruin M, Zevenhoven J, Lau A, Boulter R, Cranston A, O'Connor MJ, Martin NM, Borst P, Jonkers J (2008) High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs. Proc Natl Acad Sci USA 105(44): 17079-17084.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.44
, pp. 17079-17084
-
-
Rottenberg, S.1
Jaspers, J.E.2
Kersbergen, A.3
Van Der Burg, E.4
Nygren, A.O.5
Zander, S.A.6
Derksen, P.W.7
De Bruin, M.8
Zevenhoven, J.9
Lau, A.10
Boulter, R.11
Cranston, A.12
O'Connor, M.J.13
Martin, N.M.14
Borst, P.15
Jonkers, J.16
-
51
-
-
77950023283
-
PARP inhibition: PARP1 and beyond
-
Rouleau M, Patel A, Hendzel MJ, Kaufmann SH, Poirier GG (2010) PARP inhibition: PARP1 and beyond. Nat Rev Cancer 10(4): 293-301.
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.4
, pp. 293-301
-
-
Rouleau, M.1
Patel, A.2
Hendzel, M.J.3
Kaufmann, S.H.4
Poirier, G.G.5
-
52
-
-
0000622931
-
Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil
-
Safa AR (1988) Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil. Proc Natl Acad Sci USA 85(19): 7187-7191.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, Issue.19
, pp. 7187-7191
-
-
Safa, A.R.1
-
53
-
-
39849106300
-
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
-
Sakai W, Swisher EM, Karlan BY, Agarwal MK, Higgins J, Friedman C, Villegas E, Jacquemont C, Farrugia DJ, Couch FJ, Urban N, Taniguchi T (2008) Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers. Nature 451(7182): 1116-1120.
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1116-1120
-
-
Sakai, W.1
Swisher, E.M.2
Karlan, B.Y.3
Agarwal, M.K.4
Higgins, J.5
Friedman, C.6
Villegas, E.7
Jacquemont, C.8
Farrugia, D.J.9
Couch, F.J.10
Urban, N.11
Taniguchi, T.12
-
54
-
-
0022457103
-
Human multidrug-resistant cell lines: Increased mdr1 expression can precede gene amplification
-
Shen DW, Fojo A, Chin JE, Roninson IB, Richert N, Pastan I, Gottesman MM (1986) Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification. Science 232(4750): 643-645.
-
(1986)
Science
, vol.232
, Issue.4750
, pp. 643-645
-
-
Shen, D.W.1
Fojo, A.2
Chin, J.E.3
Roninson, I.B.4
Richert, N.5
Pastan, I.6
Gottesman, M.M.7
-
56
-
-
0030738096
-
Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein
-
Sikic BI, Fisher GA, Lum BL, Halsey J, Beketic-Oreskovic L, Chen G (1997) Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein. Cancer Chemother Pharmacol 40: Suppl: S13-S19.
-
(1997)
Cancer Chemother Pharmacol
, vol.40
, pp. S13-S19
-
-
Sikic, B.I.1
Fisher, G.A.2
Lum, B.L.3
Halsey, J.4
Beketic-Oreskovic, L.5
Chen, G.6
-
57
-
-
84867395354
-
Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer
-
Smith G, Ng MT, Shepherd L, Herrington CS, Gourley C, Ferguson MJ, Wolf CR (2012) Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer Br J Cancer 107(8):1327-1336.
-
(2012)
Br J Cancer
, vol.107
, Issue.8
, pp. 1327-1336
-
-
Smith, G.1
Ng, M.T.2
Shepherd, L.3
Herrington, C.S.4
Gourley, C.5
Ferguson, M.J.6
Wolf, C.R.7
-
58
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Smyth GK (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3: Article3.
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
-
-
Smyth, G.K.1
-
59
-
-
84925270121
-
An update on PARP inhibitors-moving to the adjuvant setting
-
Sonnenblick A, de Azambuja E, Azim Jr. HA, Piccart M (2015) An update on PARP inhibitors-moving to the adjuvant setting. Nat Rev Clin Oncol 12(1): 27-41.
-
(2015)
Nat Rev Clin Oncol
, vol.12
, Issue.1
, pp. 27-41
-
-
Sonnenblick, A.1
De Azambuja, E.2
Azim, H.A.3
Piccart, M.4
-
60
-
-
42349096328
-
Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance
-
Swisher EM, Sakai W, Karlan BY, Wurz K, Urban N, Taniguchi T (2008) Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance. Cancer Res 68(8): 2581-2586.
-
(2008)
Cancer Res
, vol.68
, Issue.8
, pp. 2581-2586
-
-
Swisher, E.M.1
Sakai, W.2
Karlan, B.Y.3
Wurz, K.4
Urban, N.5
Taniguchi, T.6
-
61
-
-
79955509238
-
Pololike kinase Plk2 is an epigenetic determinant of chemosensitivity and clinical outcomes in ovarian cancer
-
Syed N, Coley HM, Sehouli J, Koensgen D, Mustea A, Szlosarek P, McNeish I, Blagden SP, Schmid P, Lovell DP, Hatzimichael E, Crook T (2011) Pololike kinase Plk2 is an epigenetic determinant of chemosensitivity and clinical outcomes in ovarian cancer. Cancer Res 71(9): 3317-3327.
-
(2011)
Cancer Res
, vol.71
, Issue.9
, pp. 3317-3327
-
-
Syed, N.1
Coley, H.M.2
Sehouli, J.3
Koensgen, D.4
Mustea, A.5
Szlosarek, P.6
McNeish, I.7
Blagden, S.P.8
Schmid, P.9
Lovell, D.P.10
Hatzimichael, E.11
Crook, T.12
-
62
-
-
69049090809
-
Cediranib (recentin, AZD2171) reverses ABCB1-and ABCC1-mediated multidrug resistance by inhibition of their transport function
-
Tao LY, Liang YJ, Wang F, Chen LM, Yan YY, Dai CL, Fu LW (2009) Cediranib (recentin, AZD2171) reverses ABCB1-and ABCC1-mediated multidrug resistance by inhibition of their transport function. Cancer Chemother Pharmacol 64(5): 961-969.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, Issue.5
, pp. 961-969
-
-
Tao, L.Y.1
Liang, Y.J.2
Wang, F.3
Chen, L.M.4
Yan, Y.Y.5
Dai, C.L.6
Fu, L.W.7
-
63
-
-
0030969847
-
Evidence for divergence of DNA copy number changes in serous, mucinous and endometrioid ovarian carcinomas
-
Tapper J, Butzow R, Wahlstrom T, Seppala M, Knuutila S (1997) Evidence for divergence of DNA copy number changes in serous, mucinous and endometrioid ovarian carcinomas. Br J Cancer 75(12): 1782-1787.
-
(1997)
Br J Cancer
, vol.75
, Issue.12
, pp. 1782-1787
-
-
Tapper, J.1
Butzow, R.2
Wahlstrom, T.3
Seppala, M.4
Knuutila, S.5
-
64
-
-
0037358040
-
Overcoming multidrug resistance in cancer: An update on the clinical strategy of inhibiting p-glycoprotein
-
Thomas H, Coley HM (2003) Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein. Cancer Control 10(2): 159-165.
-
(2003)
Cancer Control
, vol.10
, Issue.2
, pp. 159-165
-
-
Thomas, H.1
Coley, H.M.2
-
65
-
-
77955019276
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
-
Tutt A, Robson M, Garber JE, Domchek SM, Audeh MW, Weitzel JN, Friedlander M, Arun B, Loman N, Schmutzler RK, Wardley A, Mitchell G, Earl H, Wickens M, Carmichael J (2010) Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet 376(9737): 235-244.
-
(2010)
Lancet
, vol.376
, Issue.9737
, pp. 235-244
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
Domchek, S.M.4
Audeh, M.W.5
Weitzel, J.N.6
Friedlander, M.7
Arun, B.8
Loman, N.9
Schmutzler, R.K.10
Wardley, A.11
Mitchell, G.12
Earl, H.13
Wickens, M.14
Carmichael, J.15
-
66
-
-
80053168788
-
Rethinking ovarian cancer: Recommendations for improving outcomes
-
Vaughan S, Coward JI, Bast Jr RC, Berchuck A, Berek JS, Brenton JD, Coukos G, Crum CC, Drapkin R, Etemadmoghadam D, Friedlander M, Gabra H, Kaye SB, Lord CJ, Lengyel E, Levine DA, McNeish IA, Menon U, Mills GB, Nephew KP, Oza AM, Sood AK, Stronach EA, Walczak H, Bowtell DD, Balkwill FR (2011) Rethinking ovarian cancer: recommendations for improving outcomes. Nat Rev Cancer 11(10): 719-725.
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.10
, pp. 719-725
-
-
Vaughan, S.1
Coward, J.I.2
Bast, R.C.3
Berchuck, A.4
Berek, J.S.5
Brenton, J.D.6
Coukos, G.7
Crum, C.C.8
Drapkin, R.9
Etemadmoghadam, D.10
Friedlander, M.11
Gabra, H.12
Kaye, S.B.13
Lord, C.J.14
Lengyel, E.15
Levine, D.A.16
McNeish, I.A.17
Menon, U.18
Mills, G.B.19
Nephew, K.P.20
Oza, A.M.21
Sood, A.K.22
Stronach, E.A.23
Walczak, H.24
Bowtell, D.D.25
Balkwill, F.R.26
more..
-
67
-
-
33644756522
-
Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines
-
Wang YC, Juric D, Francisco B, Yu RX, Duran GE, Chen GK, Chen X, Sikic BI (2006) Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines. Genes Chromosomes Cancer 45(4): 365-374.
-
(2006)
Genes Chromosomes Cancer
, vol.45
, Issue.4
, pp. 365-374
-
-
Wang, Y.C.1
Juric, D.2
Francisco, B.3
Yu, R.X.4
Duran, G.E.5
Chen, G.K.6
Chen, X.7
Sikic, B.I.8
-
68
-
-
26444530671
-
Major contribution of the multidrug transporter P-glycoprotein to reduced susceptibility of poly(ADP-ribose) polymerase-1 knock-out cells to doxorubicin action
-
Wesierska-Gadek J (2005) Major contribution of the multidrug transporter P-glycoprotein to reduced susceptibility of poly(ADP-ribose) polymerase-1 knock-out cells to doxorubicin action. J Cell Biochem 95(5): 1012-1028.
-
(2005)
J Cell Biochem
, vol.95
, Issue.5
, pp. 1012-1028
-
-
Wesierska-Gadek, J.1
-
69
-
-
0033881017
-
Increased resistance to anticancer therapy of mouse cells lacking the poly(ADP-ribose) polymerase attributable to up-regulation of the multidrug resistance gene product P-glycoprotein
-
Wurzer G, Herceg Z, Wesierska-Gadek J (2000) Increased resistance to anticancer therapy of mouse cells lacking the poly(ADP-ribose) polymerase attributable to up-regulation of the multidrug resistance gene product P-glycoprotein. Cancer Res 60(15): 4238-4244.
-
(2000)
Cancer Res
, vol.60
, Issue.15
, pp. 4238-4244
-
-
Wurzer, G.1
Herceg, Z.2
Wesierska-Gadek, J.3
-
70
-
-
84930678981
-
REV7 counteracts DNA double-strand break resection and affects PARP inhibition
-
Xu G, Chapman JR, Brandsma I, Yuan J, Mistrik M, Bouwman P, Bartkova J, Gogola E, Warmerdam D, Barazas M, Jaspers JE, Watanabe K, Pieterse M, Kersbergen A, Sol W, Celie PH, Schouten PC, van den Broek B, Salman A, Nieuwland M, de Rink I, de Ronde J, Jalink K, Boulton SJ, Chen J, van Gent DC, Bartek J, Jonkers J, Borst P, Rottenberg S (2015) REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature 521(7553): 541-544.
-
(2015)
Nature
, vol.521
, Issue.7553
, pp. 541-544
-
-
Xu, G.1
Chapman, J.R.2
Brandsma, I.3
Yuan, J.4
Mistrik, M.5
Bouwman, P.6
Bartkova, J.7
Gogola, E.8
Warmerdam, D.9
Barazas, M.10
Jaspers, J.E.11
Watanabe, K.12
Pieterse, M.13
Kersbergen, A.14
Sol, W.15
Celie, P.H.16
Schouten, P.C.17
Van Den Broek, B.18
Salman, A.19
Nieuwland, M.20
De Rink, I.21
De Ronde, J.22
Jalink, K.23
Boulton, S.J.24
Chen, J.25
Van Gent, D.C.26
Bartek, J.27
Jonkers, J.28
Borst, P.29
Rottenberg, S.30
more..
-
71
-
-
84923369709
-
MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer
-
Yang X, Iyer AK, Singh A, Choy E, Hornicek FJ, Amiji MM, Duan Z (2015) MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer. Sci Rep 5: 8509.
-
(2015)
Sci Rep
, vol.5
, pp. 8509
-
-
Yang, X.1
Iyer, A.K.2
Singh, A.3
Choy, E.4
Hornicek, F.J.5
Amiji, M.M.6
Duan, Z.7
-
72
-
-
84926203654
-
Cinnamaldehyde derivative (CB-PIC) sensitizes chemo-resistant cancer cells to drug-induced apoptosis via suppression of MDR1 and its upstream STAT3 and AKT signalling
-
Yun M, Lee D, Park MN, Kim EO, Sohn EJ, Kwon BM, Kim SH (2015) Cinnamaldehyde derivative (CB-PIC) sensitizes chemo-resistant cancer cells to drug-induced apoptosis via suppression of MDR1 and its upstream STAT3 and AKT signalling. Cell Physiol Biochem 35(5): 1821-1830.
-
(2015)
Cell Physiol Biochem
, vol.35
, Issue.5
, pp. 1821-1830
-
-
Yun, M.1
Lee, D.2
Park, M.N.3
Kim, E.O.4
Sohn, E.J.5
Kwon, B.M.6
Kim, S.H.7
-
73
-
-
84856875047
-
Treatment-related protein biomarker expression differs between primary and recurrent ovarian carcinomas
-
Zajchowski DA, Karlan BY, Shawver LK (2012) Treatment-related protein biomarker expression differs between primary and recurrent ovarian carcinomas. Mol Cancer Ther 11(2): 492-502.
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.2
, pp. 492-502
-
-
Zajchowski, D.A.1
Karlan, B.Y.2
Shawver, L.K.3
|