Fructo-oligosaccharide improved brain β-amyloid, β-secretase, cognitive function, and plasma antioxidant levels in D-galactose-treated Balb/cJ mice

Nutritional Neuroscience

Volumn 20, Issue 4, 2017, Pages 228-237

  Yen, Chi Hua ^a,b   Wang, Cheng Hsin ^c   Wu, Wen Tzu ^d   Chen, Hsiao Ling ^d,e  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c PROVIDENCE UNIVERSITY   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

^e CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Alzheimer; Amyloid precursor cleaving enzyme; d Galactose; Fructo oligosaccharides; Amyloid

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; ANTIOXIDANT; ASCORBIC ACID; BETA SECRETASE; FRUCTOSE OLIGOSACCHARIDE; GALACTOSE; OLIGOSACCHARIDE; SECRETASE;

ALZHEIMER DISEASE; ANIMAL MODEL; ARTICLE; BRAIN DAMAGE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DIETARY INTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPATIAL LEARNING; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; BLOOD; BRAIN; CHEMICALLY INDUCED; COGNITION DISORDERS; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM;

ALPHA-TOCOPHEROL; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; BRAIN; COGNITION; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GALACTOSE; MALE; MICE; MICE, INBRED BALB C; OLIGOSACCHARIDES;

EID: 84978512257     PISSN: 1028415X     EISSN: 14768305     Source Type: Journal    
DOI: 10.1080/1028415X.2015.1110952     Document Type: Article

References (48)

1. Jayasena T, Poljak A, Smythe G, Braidy N, Münch G, Sachdev P. The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease. Ageing Res Rev 2013;12(4):867–83. doi:10.1016/j.arr.2013.06.003
2. Masaki KH, Losonczy KG, Izmirlian G, Foley DJ, Ross GW, Petrovitch H, et al. Association of vitamin E and C supplement use with cognitive function and dementia in elderly men. Neurology 2000;54(6):1265–72. doi:10.1212/WNL.54.6.1265
3. Heo JH, Hyon L, Lee KM. The possible role of antioxidant vitamin C in Alzheimer's disease treatment and prevention. Am J Alzheimers Dis Other Demen 2013;28(2):120–5. doi:10.1177/1533317512473193
4. Zandi PP, Anthony JC, Khachaturian AS, Stone SV, Gustafson D, Tschanz JT, et al. Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements:the Cache County Study. Arch Neurol 2004;61(1):82–8. doi:10.1001/archneur.61.1.82
5. Selkoe DJ. The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease. Trend Cell Biol 1998;8(11):447–53. doi:10.1016/S0962-8924(98)01363-4
6. Sommer B. Alzheimer's disease and the amyloid cascade hypothesis:ten years on. Curr Opin Pharmacol 2002;2(1):87–92. doi:10.1016/S1471-4892(01)00126-6
7. Butterfield DA. Amyloid beta-peptide (1–42)-induced oxidative stress and neurotoxicity:implications for neurodegeneration in Alzheimer's disease brain. A review. Free Radic Res 2002;36(12):1307–13. doi:10.1080/1071576021000049890
8. Reynolds A, Laurie C, Mosley RL, Gendelman HE. Oxidative stress and the pathogenesis of neurodegenerative disorders. Int Rev Neurobiol 2007;82:297–325. doi:10.1016/S0074-7742(07)82016-2
9. Wang Q, Rowan MJ, Anwyl R. Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide. J Neurosci 2004;24(27):6049–56. doi:10.1523/JNEUROSCI.0233-04.2004
10. Iwata N, Mizukami H, Shirotani K, Takaki Y, Muramatsu S, Lu B, et al. Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain. J Neurosci 2004;24(4):991–8. doi:10.1523/JNEUROSCI.4792-03.2004
11. Hellström-Lindahl E, Ravid R, Nordberg A. Age-dependent decline of neprilysin in Alzheimer's disease and normal brain:inverse correlation with Aβ levels. Neurobiol Aging 2008;29(2):210–21. doi:10.1016/j.neurobiolaging.2006.10.010
12. Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, et al. Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron 2003;40(6):1087–93. doi:10.1016/S0896-6273(03)00787-6
13. Ghosh AK, Gemma S, Tang J. beta-Secretase as a therapeutic target for Alzheimer's disease. Neurotherapeutics 2008;5(3):399–408. doi:10.1016/j.nurt.2008.05.007
14. Hampel H, Shen Y. Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease. Scand J Clin Lab Invest 2009;69(1):8–12. doi:10.1080/00365510701864610
15. Hsia CH, Wang CH, Kuo YW, Ho YJ, Chen HL. Fructo-oligosaccharide systemically diminished D-galactose-induced oxidative molecule damages in BALB/cJ mice. Br J Nutr 2012;107(12):1787–92. doi:10.1017/S0007114511005150
16. Cui X, Zuo P, Zhang Q, Li X, Hu Y, Long J, et al. Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice:protective effects of R-alpha-lipoic acid. J Neurosci Res 2006;83(8):1584–90. doi:10.1002/jnr.20845
17. Xu XH, Zhao TQ. Effects of puerarin on D-galactose-induced memory deficits in mice. Acta Pharmacol Sin 2002;23(7):587–90.
18. Lu J, Zheng YL, Wu DM, Luo L, Sun DX, Shan Q. Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose. Biochem Pharmacol 2007;74(7):1078–90. doi:10.1016/j.bcp.2007.07.007
19. Zheng N, Yuan P, Li C, Wu J, Huang J. Luteolin reduces BACE1 expression through NF-kappaB and estrogen receptor mediated pathways in HEK293 and SH-SY5Y Cells. J Alzheimers Dis 2015; 45(2):659–71.
20. Wobst HJ, Sharma A, Diamond MI, Wanker EE, Bieschke J. The green tea polyphenol (−)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios. FEBS Lett 2015;589(1):77–83. doi:10.1016/j.febslet.2014.11.026
21. Gibson GR. Dietary modulation of the human gut microflora using the prebiotics oligofructose and inulin. J Nutr 1999;129(7 Suppl):1438S–41S.
22. Yen C-H, Kuo Y-W, Tseng Y-H, Lee M-C, Chen H-L. Beneficial effects of fructo-oligosaccharides supplementation on fecal bifidobacteria and index of peroxidation status in constipated nursing-home residents--a placebo-controlled, diet-controlled trial. Nutrition 2011;27(3):323–8. doi:10.1016/j.nut.2010.02.009
23. Chen H-L, Lu Y-H, Lin J-J, Ko L-Y. Effects of fructooligosaccharide on bowel function and indicators of nutritional status in constipated elderly men. Nutr Res 2000;20(12):1725–33. doi:10.1016/S0271-5317(00)00274-8
24. Hsieh HM, Wu WM, Hu ML. Soy isoflavones attenuate oxidative stress and improve parameters related to aging and Alzheimer's disease in C57BL/6J mice treated with D-galactose. Food Chem Toxicol 2009;47(3):625–32. doi:10.1016/j.fct.2008.12.026
25. National Institute of Health. Guide for the care and use of laboratory animals (Publication 85–23, Rev.). Bethesda, MD:National Research Council, National Institute of Health; 1985.
26. Burton MS, Leonard CM. A stereotaxic atlas of the Albino Mouse Forebrain. Rockville, MD:US Dept. Health, Education and Welfare; 1975.
27. Wei H, Li L, Song Q, Ai H, Chu J, Li W. Behavioural study of the D-galactose induced aging model in C57BL/6J mice. Behav Brain Res 2005;157(2):245–51. doi:10.1016/j.bbr.2004.07.003
28. Ching SY, Prins AW, Beilby JP. Stability of ascorbic acid in serum and plasma prior to analysis. Ann Clin Biochem 2002;39(Pt 5):518–20. doi:10.1258/000456302320314566
29. Catignani GL, Bieri JG. Simultaneous determination of retinol and alpha-tocopherol in serum or plasma by liquid chromatography. Clin Chem 1983;29(4):708–12.
30. Luo Y, Niu F, Sun Z, Cao W, Zhang X, Guan D, et al. Altered expression of Abeta metabolism-associated molecules from D-galactose/AlCl(3) induced mouse brain. Mech Ageing Dev 2009;130(4):248–52. doi:10.1016/j.mad.2008.12.005
31. Franceschi C, Capri M, Monti D, Giunta S, Olivieri F, Sevini F, et al. Inflammaging and anti-inflammaging:a systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev 2007;128(1):92–105. doi:10.1016/j.mad.2006.11.016
32. Mallidis C, Agbaje I, Rogers D, Glenn J, McCullough S, Atkinson AB, et al. Distribution of the receptor for advanced glycation end products in the human male reproductive tract:prevalence in men with diabetes mellitus. Hum Reprod 2007;22(8):2169–77. doi:10.1093/humrep/dem156
33. Ho SC, Liu JH, Wu RY. Establishment of the mimetic aging effect in mice caused by D-galactose. Biogerontology 2003;4(1):15–8. doi:10.1023/A:1022417102206
34. Guerreiro RJ, Gustafson DR, Hardy J. The genetic architecture of Alzheimer's disease:beyond APP, PSENs and APOE. Neurobiol Aging 2012;33(3):437–56. doi:10.1016/j.neurobiolaging.2010.03.025
35. St George-Hyslop PH, Petit A. Molecular biology and genetics of Alzheimer's disease. C R Biol 2005;328(2):119–30. doi:10.1016/j.crvi.2004.10.013
36. Vina J, Lloret A, Giraldo E, Badia MC, Alonso MD. Antioxidant pathways in Alzheimer's disease:possibilities of intervention. Curr Pharm Des 2011;17(35):3861–4. doi:10.2174/138161211798357755
37. Yeh S-L, Wu T-C, Chan S-T, Hong M-J, Chen H-L. Fructo-oligosaccharide attenuates the production of pro-inflammatory cytokines and the activation of JNK/Jun pathway in the lungs of D-galactose-treated Balb/cJ mice. Eur J Nutr 2014;53(2):449–56. doi:10.1007/s00394-013-0545-3
38. Tamagno E, Guglielmotto M, Aragno M, Borghi R, Autelli R, Giliberto L, et al. Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. J Neurochem 2008;104(3):683–95.
39. Crews L, Rockenstein E, Masliah E. APP transgenic modeling of Alzheimer's disease:mechanisms of neurodegeneration and aberrant neurogenesis. Brain Struct Funct 2010;214(2–3):111–26. doi:10.1007/s00429-009-0232-6
40. Nikolaev A, McLaughlin T, O'Leary DD, Tessier-Lavigne M. APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature 2009;457(7232):981–9. doi:10.1038/nature07767
41. Joshi YB, Pratico D. Vitamin E in aging, dementia, and Alzheimer's disease. Biofactors 2012;38(2):90–7. doi:10.1002/biof.195
42. Li FJ, Shen L, Ji HF. Dietary intakes of vitamin E, vitamin C, and beta-carotene and risk of Alzheimer's disease:a meta-analysis. J Alzheimers Dis 2012;31(2):253–8.
43. Chen H-L, Wang C-H, Kuo Y-W, Tsai C-H. Antioxidative and hepatoprotective effects of fructo-oligosaccharide in d-galactose-treated Balb/cJ mice. Br J Nutr 2011;105(6):805–9. doi:10.1017/S000711451000437X
44. Ito M, Kimura M, Deguchi Y, Miyamori-Watabe A, Yajima T, Kan T. Effects of transgalactosylated disaccharides on the human intestinal microflora and their metabolism. J Nutr Sci Vitaminol (Tokyo) 1993;39(3):279–88. doi:10.3177/jnsv.39.279
45. Kaizu H, Masahiro S, Hajime N, Yutaka S. Effect of antioxidative lactic acid bacteria on rats fed a diet deficient in vitamin E. J Dairy Sci 1993;76(9):2493–9. doi:10.3168/jds.S0022-0302(93)77584-0
46. Oku T, Nakamura S. Comparison of digestibility and breath hydrogen gas excretion of fructo-oligosaccharide, galactosyl-sucrose, and isomalto-oligosaccharide in healthy human subjects. Eur J Clin Nutr 2003;57(9):1150–6. doi:10.1038/sj.ejcn.1601666
47. Lee JW, Kim JI, Lee YA, Lee DH, Song CS, Cho YJ, et al. Inhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats. J Pediatr Surg 2012;47(4):736–42. doi:10.1016/j.jpedsurg.2011.09.035
48. Kato R, Nomura A, Sakamoto A, Yasuda Y, Amatani K, Nagai S, et al. Hydrogen gas attenuates embryonic gene expression and prevents left ventricular remodeling induced by intermittent hypoxia in cardiomyopathic hamsters. Am J Physiol Heart Circ Physiol 2014;307(11):H1626–33. doi:10.1152/ajpheart.00228.2014