메뉴 건너뛰기




Volumn 148, Issue 4, 2016, Pages 377-386

Hepatitis C virus-induced myeloid-derived suppressor cells regulate T-cell differentiation and function via the signal transducer and activator of transcription 3 pathway

Author keywords

hepatitis C virus; interleukin 10; myeloid derived suppressor cells; regulatory T cells; signal transducer and activator of transcription 3

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; CD33 ANTIGEN; CD4 ANTIGEN; CORE PROTEIN; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3;

EID: 84978476478     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12616     Document Type: Article
Times cited : (46)

References (48)
  • 1
    • 84892449551 scopus 로고    scopus 로고
    • Immune responses to HCV and other hepatitis viruses
    • Park SH, Rehermann B. Immune responses to HCV and other hepatitis viruses. Immunity 2014; 40:13–24.
    • (2014) Immunity , vol.40 , pp. 13-24
    • Park, S.H.1    Rehermann, B.2
  • 2
    • 84885060120 scopus 로고    scopus 로고
    • Emerging concepts in immunity to hepatitis C virus infection
    • Rosen HR. Emerging concepts in immunity to hepatitis C virus infection. J Clin Invest 2013; 123:4121–30.
    • (2013) J Clin Invest , vol.123 , pp. 4121-4130
    • Rosen, H.R.1
  • 3
    • 84890947330 scopus 로고    scopus 로고
    • Novel therapeutic approaches for hepatitis C
    • Au JS, Pockros PJ. Novel therapeutic approaches for hepatitis C. Clin Pharmacol Ther 2014; 95:78–88.
    • (2014) Clin Pharmacol Ther , vol.95 , pp. 78-88
    • Au, J.S.1    Pockros, P.J.2
  • 4
    • 84881314351 scopus 로고    scopus 로고
    • Novel therapies for hepatitis C – one pill fits all?
    • Manns MP, von Hahn T. Novel therapies for hepatitis C – one pill fits all? Nat Rev Drug Discov 2013; 12:595–610.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 595-610
    • Manns, M.P.1    von Hahn, T.2
  • 5
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: linking inflammation and cancer
    • Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 2009; 182:4499–506.
    • (2009) J Immunol , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 6
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9:162–74.
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 7
    • 84924023676 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: paradoxical roles in infection and immunity
    • Dai J, El Gazzar M, Li GY, Moorman JP, Yao ZQ. Myeloid-derived suppressor cells: paradoxical roles in infection and immunity. J Innate Immun 2014; 7:116–26.
    • (2014) J Innate Immun , vol.7 , pp. 116-126
    • Dai, J.1    El Gazzar, M.2    Li, G.Y.3    Moorman, J.P.4    Yao, Z.Q.5
  • 8
    • 66949145484 scopus 로고    scopus 로고
    • Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells
    • Corzo CA, Cotter MJ, Cheng P, Cheng F, Kusmartsev S, Sotomayor E et al. Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells. J Immunol 2009; 182:5693–701.
    • (2009) J Immunol , vol.182 , pp. 5693-5701
    • Corzo, C.A.1    Cotter, M.J.2    Cheng, P.3    Cheng, F.4    Kusmartsev, S.5    Sotomayor, E.6
  • 11
    • 34447258415 scopus 로고    scopus 로고
    • Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte–macrophage colony-stimulation factor-based antitumor vaccine
    • Filipazzi P, Valenti R, Huber V, Pilla L, Canese P, Iero M et al. Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte–macrophage colony-stimulation factor-based antitumor vaccine. J Clin Oncol 2007; 25:2546–53.
    • (2007) J Clin Oncol , vol.25 , pp. 2546-2553
    • Filipazzi, P.1    Valenti, R.2    Huber, V.3    Pilla, L.4    Canese, P.5    Iero, M.6
  • 13
    • 84864662070 scopus 로고    scopus 로고
    • Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
    • Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med 2012; 18:1254–61.
    • (2012) Nat Med , vol.18 , pp. 1254-1261
    • Walter, S.1    Weinschenk, T.2    Stenzl, A.3    Zdrojowy, R.4    Pluzanska, A.5    Szczylik, C.6
  • 14
    • 84875866083 scopus 로고    scopus 로고
    • STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients
    • Vasquez-Dunddel D, Pan F, Zeng Q, Gorbounov M, Albesiano E, Fu J et al. STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients. J Clin Invest 2013; 123:1580–9.
    • (2013) J Clin Invest , vol.123 , pp. 1580-1589
    • Vasquez-Dunddel, D.1    Pan, F.2    Zeng, Q.3    Gorbounov, M.4    Albesiano, E.5    Fu, J.6
  • 16
    • 80052646150 scopus 로고    scopus 로고
    • Immunosuppressive functions of hepatic myeloid-derived suppressor cells of normal mice and in a murine model of chronic hepatitis B virus
    • Chen S, Akbar SM, Abe M, Hiasa Y, Onji M. Immunosuppressive functions of hepatic myeloid-derived suppressor cells of normal mice and in a murine model of chronic hepatitis B virus. Clin Exp Immunol 2011; 166:134–42.
    • (2011) Clin Exp Immunol , vol.166 , pp. 134-142
    • Chen, S.1    Akbar, S.M.2    Abe, M.3    Hiasa, Y.4    Onji, M.5
  • 17
    • 84912571542 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells regulate immune response in patients with chronic hepatitis B virus infection through PD-1-induced IL-10
    • Huang A, Zhang B, Yan WW, Wang B, Wei HF, Zhang F et al. Myeloid-derived suppressor cells regulate immune response in patients with chronic hepatitis B virus infection through PD-1-induced IL-10. J Immunol 2014; 193:5461–9.
    • (2014) J Immunol , vol.193 , pp. 5461-5469
    • Huang, A.1    Zhang, B.2    Yan, W.W.3    Wang, B.4    Wei, H.F.5    Zhang, F.6
  • 18
    • 84864289043 scopus 로고    scopus 로고
    • Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells
    • Vollbrechi T, Striner R, Tufman A, Roider J, Huber RM, Bogner JR et al. Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells. AIDS 2012; 26:F31–7.
    • (2012) AIDS , vol.26 , pp. F31-F37
    • Vollbrechi, T.1    Striner, R.2    Tufman, A.3    Roider, J.4    Huber, R.M.5    Bogner, J.R.6
  • 19
    • 84864213428 scopus 로고    scopus 로고
    • MDSC: a new player in HIV immunopathogenesis
    • Macatangay BJ, Landay AL, Rinaldo CR. MDSC: a new player in HIV immunopathogenesis. AIDS 2012; 26:1567–9.
    • (2012) AIDS , vol.26 , pp. 1567-1569
    • Macatangay, B.J.1    Landay, A.L.2    Rinaldo, C.R.3
  • 20
    • 84873049826 scopus 로고    scopus 로고
    • Expansion of monocytic myeloid-derived suppressor cells dampens T cell function in HIV-1-seropositive individuals
    • Qin A, Cai W, Pan T, Wu K, Yang Q, Wang N et al. Expansion of monocytic myeloid-derived suppressor cells dampens T cell function in HIV-1-seropositive individuals. J Virol 2013; 87:1477–90.
    • (2013) J Virol , vol.87 , pp. 1477-1490
    • Qin, A.1    Cai, W.2    Pan, T.3    Wu, K.4    Yang, Q.5    Wang, N.6
  • 21
    • 84892646386 scopus 로고    scopus 로고
    • HIV type 1 gp120-induced expansion of myeloid derived suppressor cells is dependent on interleukin 6 and suppresses immunity
    • Garg A, Spector SA. HIV type 1 gp120-induced expansion of myeloid derived suppressor cells is dependent on interleukin 6 and suppresses immunity. J Infect Dis 2014; 209: 441–51.
    • (2014) J Infect Dis , vol.209 , pp. 441-451
    • Garg, A.1    Spector, S.A.2
  • 23
    • 84863012062 scopus 로고    scopus 로고
    • Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species
    • Tacke RS, Lee HC, Goh C, Courtney J, Polyak SJ, Rosen HR et al. Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species. Hepatology 2012; 55:343–53.
    • (2012) Hepatology , vol.55 , pp. 343-353
    • Tacke, R.S.1    Lee, H.C.2    Goh, C.3    Courtney, J.4    Polyak, S.J.5    Rosen, H.R.6
  • 25
    • 84878017037 scopus 로고    scopus 로고
    • Clinical significance and functional studies of myeloid-derived suppressor cells in chronic hepatitis C patients
    • Cai W, Qin A, Guo P, Yan D, Hu F, Yang Q et al. Clinical significance and functional studies of myeloid-derived suppressor cells in chronic hepatitis C patients. J Clin Immunol 2013; 33:798–808.
    • (2013) J Clin Immunol , vol.33 , pp. 798-808
    • Cai, W.1    Qin, A.2    Guo, P.3    Yan, D.4    Hu, F.5    Yang, Q.6
  • 27
    • 84874260474 scopus 로고    scopus 로고
    • Chronic but not acute virus infection induces sustained expansion of myeloid suppressor cell numbers that inhibit viral-specific T cell immunity
    • Norris BA, Uebelhoer LS, Nakaya HI, Price AA, Grakoui A, Pulendran B. Chronic but not acute virus infection induces sustained expansion of myeloid suppressor cell numbers that inhibit viral-specific T cell immunity. Immunity 2013; 38:309–21.
    • (2013) Immunity , vol.38 , pp. 309-321
    • Norris, B.A.1    Uebelhoer, L.S.2    Nakaya, H.I.3    Price, A.A.4    Grakoui, A.5    Pulendran, B.6
  • 28
    • 84901992636 scopus 로고    scopus 로고
    • Lack of significant elevation of myeloid-derived suppressor cells in peripheral blood of chronically hepatitis C virus-infected individuals
    • Nonnenmann J, Stirner R, Roider J, Jung MC, Schrudl K, Bogner JR et al. Lack of significant elevation of myeloid-derived suppressor cells in peripheral blood of chronically hepatitis C virus-infected individuals. J Virol 2014; 88:7678–82.
    • (2014) J Virol , vol.88 , pp. 7678-7682
    • Nonnenmann, J.1    Stirner, R.2    Roider, J.3    Jung, M.C.4    Schrudl, K.5    Bogner, J.R.6
  • 29
    • 0035500651 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits human T lymphocyte responses by a complement-dependent regulatory pathway
    • Yao ZQ, Nguyen DT, Hiotellis AI, Hahn YS. Hepatitis C virus core protein inhibits human T lymphocyte responses by a complement-dependent regulatory pathway. J Immunol 2001; 167:5264–72.
    • (2001) J Immunol , vol.167 , pp. 5264-5272
    • Yao, Z.Q.1    Nguyen, D.T.2    Hiotellis, A.I.3    Hahn, Y.S.4
  • 31
    • 16344380754 scopus 로고    scopus 로고
    • A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells
    • Song H, Wang RX, Wang SM, Lin JY. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci USA 2005; 102:4700–5.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4700-4705
    • Song, H.1    Wang, R.X.2    Wang, S.M.3    Lin, J.Y.4
  • 33
    • 84863630845 scopus 로고    scopus 로고
    • Tim-3 pathway controls regulatory and effector T cell balance during HCV infection
    • Moorman JP, Wang JM, Zhang Y, Ji XJ, Ma CJ, Wu XY et al. Tim-3 pathway controls regulatory and effector T cell balance during HCV infection. J Immunol 2012; 189:755–66.
    • (2012) J Immunol , vol.189 , pp. 755-766
    • Moorman, J.P.1    Wang, J.M.2    Zhang, Y.3    Ji, X.J.4    Ma, C.J.5    Wu, X.Y.6
  • 35
    • 79953178933 scopus 로고    scopus 로고
    • Extracellular hepatitis C virus core protein activates STAT3 in human monocytes/macrophages/dendritic cells via an IL-6 autocrine pathway
    • Tacke RS, Tosello-Trampont A, Nguyen V, Mullins DW, Hahn SH. Extracellular hepatitis C virus core protein activates STAT3 in human monocytes/macrophages/dendritic cells via an IL-6 autocrine pathway. J Biol Chem 2011; 286:10847–55.
    • (2011) J Biol Chem , vol.286 , pp. 10847-10855
    • Tacke, R.S.1    Tosello-Trampont, A.2    Nguyen, V.3    Mullins, D.W.4    Hahn, S.H.5
  • 36
    • 28644445445 scopus 로고    scopus 로고
    • Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
    • Korrylewski M, Kujawski M, Wang T, Wei S, Zhang S, Pilon-Thomas S et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med 2005; 11: 1314–21.
    • (2005) Nat Med , vol.11 , pp. 1314-1321
    • Korrylewski, M.1    Kujawski, M.2    Wang, T.3    Wei, S.4    Zhang, S.5    Pilon-Thomas, S.6
  • 37
    • 84949223262 scopus 로고    scopus 로고
    • The correlation between pretreatment cytokine expression patterns in peripheral blood mononuclear cells with chronic hepatitis C outcome
    • Jabłońska J, Pawłowski T, Laskus T, Zalewska M, Inglot M, Osowska S et al. The correlation between pretreatment cytokine expression patterns in peripheral blood mononuclear cells with chronic hepatitis C outcome. BMC Infect Dis 2015; 15:556.
    • (2015) BMC Infect Dis , vol.15 , pp. 556
    • Jabłońska, J.1    Pawłowski, T.2    Laskus, T.3    Zalewska, M.4    Inglot, M.5    Osowska, S.6
  • 38
    • 84900299462 scopus 로고    scopus 로고
    • Depression and neuroticism in patients with chronic hepatitis C: correlation with peripheral blood mononuclear cells activation
    • Pawlowski T, Radkowski M, Małyszczak K, Inglot M, Zalewska M, Jablonska J et al. Depression and neuroticism in patients with chronic hepatitis C: correlation with peripheral blood mononuclear cells activation. J Clin Virol 2014; 60:105–11.
    • (2014) J Clin Virol , vol.60 , pp. 105-111
    • Pawlowski, T.1    Radkowski, M.2    Małyszczak, K.3    Inglot, M.4    Zalewska, M.5    Jablonska, J.6
  • 39
    • 84926160614 scopus 로고    scopus 로고
    • Acute and chronic immune biomarker changes during interferon/ribavirin treatment in HIV/HCV co-infected patients
    • Jain MK, Adams-Huet B, Terekhova D, Kushner LE, Bedimo R, Li X et al. Acute and chronic immune biomarker changes during interferon/ribavirin treatment in HIV/HCV co-infected patients. J Viral Hepat 2015; 22:25–36.
    • (2015) J Viral Hepat , vol.22 , pp. 25-36
    • Jain, M.K.1    Adams-Huet, B.2    Terekhova, D.3    Kushner, L.E.4    Bedimo, R.5    Li, X.6
  • 40
    • 0036122643 scopus 로고    scopus 로고
    • Evidence for prostaglandin-producing suppressor cells in HCV patients with normal ALT
    • Marinho R, Pinto R, Santos ML, de M. Evidence for prostaglandin-producing suppressor cells in HCV patients with normal ALT. Dig Dis Sci 2002; 47:556–61.
    • (2002) Dig Dis Sci , vol.47 , pp. 556-561
    • Marinho, R.1    Pinto, R.2    Santos, M.L.3    de, M.4
  • 41
    • 22544447811 scopus 로고    scopus 로고
    • Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication
    • Waris G, Siddigui A. Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication. J Virol 2005; 79:9725–34.
    • (2005) J Virol , vol.79 , pp. 9725-9734
    • Waris, G.1    Siddigui, A.2
  • 42
    • 37849052306 scopus 로고    scopus 로고
    • NS3 protein of hepatitis C virus regulates cyclooxygenase-2 expression through multiple signaling pathways
    • Lu L, Wei L, Peng G, Mu Y, Wu K, Kang L et al. NS3 protein of hepatitis C virus regulates cyclooxygenase-2 expression through multiple signaling pathways. Virology 2008; 371:61–70.
    • (2008) Virology , vol.371 , pp. 61-70
    • Lu, L.1    Wei, L.2    Peng, G.3    Mu, Y.4    Wu, K.5    Kang, L.6
  • 43
    • 84939947684 scopus 로고    scopus 로고
    • Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection
    • Chen JH, Perry CJ, Tsui YC, Staron MM, Parish IA, Dominguez CX et al. Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection. Nat Med 2015; 21:327–34.
    • (2015) Nat Med , vol.21 , pp. 327-334
    • Chen, J.H.1    Perry, C.J.2    Tsui, Y.C.3    Staron, M.M.4    Parish, I.A.5    Dominguez, C.X.6
  • 44
    • 84869221347 scopus 로고    scopus 로고
    • IL-10 immunomodulation of myeloid cells regulates a murine model of ovarian cancer
    • Hart KM, Byrne KT, Molloy MJ, Usherwood EM, Berwin B. IL-10 immunomodulation of myeloid cells regulates a murine model of ovarian cancer. Front Immunol 2011; 2:29.
    • (2011) Front Immunol , vol.2 , pp. 29
    • Hart, K.M.1    Byrne, K.T.2    Molloy, M.J.3    Usherwood, E.M.4    Berwin, B.5
  • 45
    • 77956920766 scopus 로고    scopus 로고
    • Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells
    • Lechner MG, Liebertz DJ, Epstein AL. Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells. J Immunol 2010; 185:2273–84.
    • (2010) J Immunol , vol.185 , pp. 2273-2284
    • Lechner, M.G.1    Liebertz, D.J.2    Epstein, A.L.3
  • 46
    • 78650756969 scopus 로고    scopus 로고
    • Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function
    • Condamine T, Gabrilovich DI. Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. Trends Immunol 2011; 32:19–25.
    • (2011) Trends Immunol , vol.32 , pp. 19-25
    • Condamine, T.1    Gabrilovich, D.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.