Multi-functionality Redefined with Colloidal Carotene Carbon Nanoparticles for Synchronized Chemical Imaging, Enriched Cellular Uptake and Therapy

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Misra, Santosh K ^a   Mukherjee, Prabuddha ^b   Chang, Huei Huei ^a   Tiwari, Saumya ^b   Gryka, Mark ^b   Bhargava, Rohit ^b   Pan, Dipanjan ^a  

^a University of Illinois at Urbana Champaign   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CAROTENE; BIOCOMPATIBLE COATED MATERIAL; CARBON; NANOPARTICLE; PHOSPHOLIPID;

CELL MEMBRANE; CHEMISTRY; COLLOID; HUMAN; METABOLISM; MICROSCOPY; NEOPLASM; OPTICAL ROTATION; TRANSPORT AT THE CELLULAR LEVEL;

BETA CAROTENE; BIOLOGICAL TRANSPORT; CARBON; CELL MEMBRANE; COATED MATERIALS, BIOCOMPATIBLE; COLLOIDS; HUMANS; MICROSCOPY; NANOPARTICLES; NEOPLASMS; OPTICAL ROTATION; PHOSPHOLIPIDS;

EID: 84978419070     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep29299     Document Type: Article

References (61)

1. Jia, F. et al. Multifunctional nanoparticles for targeted delivery of immune activating and cancer therapeutic agents. J. Control. Release 172, 1020-1034 (2013).
2. Sanvicens, N. & Marco, M. P. Multifunctional nanoparticles-properties and prospects for their use in human medicine. Trends Biotechnol. 26, 425-433 (2008).
3. Bao, G., Mitragotri, S. & Tong, S. Multifunctional nanoparticles for drug delivery and molecular imaging. Annu. Rev. Biomed. Eng. 15, 253-282 (2013).
4. Lee, D.-E. et al. Multifunctional nanoparticles for multimodal imaging and theragnosis. Chem. Soc. Rev. 41, 2656-2672 (2012).
5. Misra, S. K., Kim, B., Chang, H.-H. & Pan, D. Defying symmetry: a 'flowery' architecture with augmented surface area from gold coated polymeric 'nanoblooms'. RSC Adv. 4, 34303-34306 (2014).
6. Gindy, M. E. & Prud'homme, R. K. Multifunctional nanoparticles for imaging, delivery and targeting in cancer therapy. Expert Opin. Drug Deliv. 6, 865-878 (2009).
7. Smith, L., Kuncic, Z., (Ken) Ostrikov, K. & Kumar, S. Nanoparticles in Cancer Imaging and Therapy. J. Nanomater. 2012, 1 (2012).
8. Mukherjee, P. et al. Tunable Luminescent Carbon Nanospheres with Well-Defined Nanoscale Chemistry for Synchronized Imaging and Therapy. Small 11, 4691-4703 (2015).
9. Albanese, A., Tang, P. S. & Chan, W. C. W. The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems. Annual Review of Biomedical Engineering 14, 1-16 (2012).
10. Nikitin, M. P., Zdobnova, T. A., Lukash, S. V., Stremovskiy, O. A. & Deyev, S. M. Protein-assisted self-assembly of multifunctional nanoparticles. Proc. Natl. Acad. Sci. USA 107, 5827-5832 (2010).
11. Xiao, Y. et al. Multifunctional unimolecular micelles for cancer-targeted drug delivery and positron emission tomography imaging. Biomaterials 33, 3071-3082 (2012).
12. Misra, S. K., Ye, M., Kim, S. & Pan, D. Defined Nanoscale Chemistry Influences Delivery of Peptido-Toxins for Cancer Therapy. PLoS One 10, e0125908 (2015).
13. Misra, S. K., Jensen, T. W. & Pan, D. Enriched inhibition of cancer and stem-like cancer cells via STAT-3 modulating niclocelles. Nanoscale 7, 7127-7132 (2015).
14. Misra, S. K., Kus, J., Kim, S. & Pan, D. Nanoscopic poly-DNA-cleaver for breast cancer regression with induced oxidative damage. Mol. Pharm. 11, 4218-4227 (2014).
15. Misra, S. K., Ye, M., Kim, S. & Pan, D. Highly efficient anti-cancer therapy using scorpion 'NanoVenin'. Chem. Commun. (Camb). 50, 13220-13223 (2014).
16. Kiessling, F., Mertens, M. E., Grimm, J. & Lammers, T. Nanoparticles for Imaging: Top or Flop? Radiology. 273, 10-28 (2014).
17. Lee, K. J., Nallathamby, P. D., Browning, L. M., Osgood, C. J. & Xu, X.-H. N. In Vivo Imaging of Transport and Biocompatibility of Single Silver Nanoparticles in Early Development of Zebrafish Embryos. ACS Nano 2007, 1, 133.
18. Altinoǧlu, E. I. et al. Near-Infrared Emitting Fluorophore-Doped Calcium Phosphate Nanoparticles for In Vivo Imaging of Human Breast Cancer. ACS Nano 2, 2075-2084 (2008).
19. Patra, C. R., Bhattacharya, R., Mukhopadhyay, D. & Mukherjee, P. Fabrication of Gold Nanoparticles for targeted therapy in pancreatic cancer. Adv. Drug Deliv. Rev. 62, 346-361 (2010).
20. Bhattacharya, R. et al. Attaching folic acid on gold nanoparticles using noncovalent interaction via different polyethylene glycol backbones and targeting of cancer cells. Nanomedicine Nanotechnology, Biol. Med. 3, 224-238 (2007).
21. Deng, L. et al. Two-Step" Raman Imaging Technique To Guide Chemo-Photothermal Cancer Therapy. Chemistry doi: 10.1002/ chem.201502522 (2015).
22. Yang, K. et al. Multimodal imaging guided photothermal therapy using functionalized graphene nanosheets anchored with magnetic nanoparticles. Adv. Mater. 24, 1868-1872 (2012).
23. Miller-Kleinhenz, J. M., Bozeman, E. N. & Yang, L. Targeted nanoparticles for image-guided treatment of triple-negative breast cancer: clinical significance and technological advances. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 7, 797-816 (2015).
24. Anker, J. N. et al. Biosensing with plasmonic nanosensors. Nat. Mater. 7, 442-453 (2008).
25. Misra, S. K., Kim, B., Kolmodin, N. J. & Pan, D. A dual strategy for sensing metals with a nano 'pincer' scavenger for in vitro diagnostics and detection of liver diseases from blood samples. Colloids Surf. B. Biointerfaces 126, 444-451 (2015).
26. Smith, J. E., Wang, L. & Tan, W. Bioconjugated silica-coated nanoparticles for bioseparation and bioanalysis. TrAC Trends Anal. Chem. 25, 848-855 (2006).
27. Wei, L. et al. Fabrication of bright and small size semiconducting polymer nanoparticles for cellular labelling and single particle tracking. Nanoscale 6, 11351-11358 (2014).
28. Misra, S. K., Ohoka, A., Kolmodin, N. J. & Pan, D. Next generation carbon nanoparticles for efficient gene therapy. Mol. Pharm. 12, 375-385 (2015).
29. Netti, P. A., Berk, D. A., . Swartz, M. A., Grodzinsky, A. J. & Jain, R. K. Role of extracellular matrix assembly in interstitial transport in solid tumors. Cancer Res. 60, 2497-2503 (2000).
30. Pardridge, W. M. Adv. Drug Deliv. Rev. 1995, 15, 5.
31. Grassmann, J. Terpenoids as plant antioxidants. Vitam. Horm. 72, 505-535 (2005).
32. An, G.-H., Suh, O.-S., Kwon, H.-C., Kim, K. & Johnson, E. A. Quantification of carotenoids in cells of Phaffia rhodozyma by autofluorescence. Biotechnol. Lett. 22, 1031-1034 (2000).
33. W. I. Gruszecki Carotenoids in membranes; Frank, H. A., Young, A. J., Britton, G., Cogdell, R. J. Eds. Kluwer Academic Publishers, Dordrecht, 1999.
34. Kutuzov, N. P. et al. Orientational ordering of carotenoids in myelin membranes resolved by polarized Raman microspectroscopy. Biophys. J. 2014, 107, 891.
35. Van de Ven, M., Kattenberg, M., Van Ginkel, G. & Levine, Y. K. Study of the orientational ordering of carotenoids in lipid bilayers by resonance-Raman spectroscopy. Biophys. J. 45, 1203-1209 (1984).
36. Hoskins, L. C. Resonance Raman spectroscopy of beta-carotene and lycopene, a physical chemistry experiment. J. Chem. Educ. 61, 460 (1984).
37. Rimai, L., Heyde, M. E. & Gill, D. Vibrational spectra of some carotenoids and related linear polyenes. Raman spectroscopic study. J. Am. Chem. Soc. 95, 4493-4501 (1973).
38. Paiva, S. A. & Russell, R. M. Beta-carotene and other carotenoids as antioxidants. J. Am. Coll. Nutr. 18, 426-433 (1999).
39. Cerezo, J. et al. Antioxidant properties of β -carotene isomers and their role in photosystems: insights from Ab initio simulations. J. Phys. Chem. A 116, 3498-3506 (2012).
40. Gyémánt, N. et al. Reversal of multidrug resistance of cancer cells in vitro: modification of drug resistance by selected carotenoids. Anticancer Res. 26, 367-374 (2006).
41. Palozza, P. et al. Effect of beta-carotene-rich tomato lycopene beta-cyclase ( tlcy-b) on cell growth inhibition in HT-29 colon adenocarcinoma cells. Br. J. Nutr. 102, 207-214 (2009).
42. Lim, J. Y., Kim, Y.-S., Kim, K.-M., Min, S. J. & Kim, Y. β -carotene inhibits neuroblastoma tumorigenesis by regulating cell differentiation and cancer cell stemness. Biochem. Biophys. Res. Commun. 450, 1475-1480 (2014).
43. Peetla, C., Stine, A. & Labhasetwar, V. Biophysical interactions with model lipid membranes: applications in drug discovery and drug delivery. Mol. Pharm. 6, 1264-1276 (2009).
44. Roiter, Y. et al. Interaction of nanoparticles with lipid membrane. Nano Lett. 8, 941-944 (2008).
45. Ruiz de Garibay, A. P., Solinís Aspiazu, M. Á., Rodríguez Gascón, A., Ganjian, H. & R. Fuchs Role of endocytic uptake in transfection efficiency of solid lipid nanoparticles-based nonviral vectors. J. Gene Med. 15, 427-440 (2013).
46. Verma, A. et al. Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles. Nat. Mater. 7, 588-595 (2008).
47. Muller, R., Mäder, K. & Gohla, S. Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art. Eur. J. Pharm. Biopharm. 50, 161-177 (2000).
48. Walsh, M. J., Holton, S. E., Kajdacsy-Balla, A. & Bhargava, R. Attenuated total reflectance Fourier-transform infrared spectroscopic imaging for breast histopathology. Vib. Spectrosc. 60, 23-28 (2012).
49. Walsh, M. J., Reddy, R. K. & Bhargava, R. Label-free biomedical imaging with mid-infrared microspectroscopy. IEEE J. Sel. Top. Quant. 18, 1502-1513 (2012).
50. Berezin, K. V. & Nechaev, V. V. Calculation of the IR Spectrum and the Molecular Structure of β -Carotene. J. Appl. Spectrosc. 72, 157-161 (2005).
51. Schlucker, S., Szeghalmi, A., Schmitt, M., Popp, J. & Kiefer, W. Structural analysis of cytochromes P450 shows differences in flexibility of heme 2- and 4-vinyls. J. Raman Spectrosc. 34, 413-419 (2003).
52. Davis, B. J., Carney, P. S. & Bhargava, R. Theory of mid-infrared absorption microspectroscopy: II. Heterogeneous samples. Anal. Chem. 82, 3487-3499 (2010).
53. Davis, B. J., Carney, P. S. & Bhargava, R. Theory of midinfrared absorption microspectroscopy: I. Homogeneous samples. Anal. Chem. 82, 3474-3486 (2010).
54. Mayerich, D. et al. On the importance of image formation optics in the design of infrared spectroscopic imaging systems. Analyst. 139, 4031-4036 (2014).
55. Bhargava, R. Infrared spectroscopic imaging: the next generation. Appl. Spectrosc. 66, 1091-1120 (2012).
56. Robertson, J. Diamond-like amorphous carbon. Mater. Sci. Eng. R Reports 37, 129-281 (2002).
57. Xie, J. et al. Berberine-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species generation and mitochondrial-related apoptotic pathway. Tumour Biol. 36, 1279-1288 (2015).
58. Cui, Y. et al. beta-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor gamma expression and reactive oxygen species production in MCF-7 cancer cells. Eur. J. Cancer 43, 2590-2601 (2007).
59. Kong, R. & Bhargava, R. Characterization of porcine skin as a model for human skin studies using infrared spectroscopic imaging. Analyst 136, 2359-2366 (2011).
60. Desai, P., Patlolla, R. R. & Singh, M. Interaction of nanoparticles and cell-penetrating peptides with skin for transdermal drug delivery. Mol. Membr. Biol. 27, 247-259 (2010).
61. Orazizadeh, M., Khorsandi, L., Absalan, F., Hashemitabar, M. & Daneshi, E. Effect of beta-carotene on titanium oxide nanoparticlesinduced testicular toxicity in mice. J. Assist. Reprod. Genet. 31, 561-568 (2014).