Berberine-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species generation and mitochondrial-related apoptotic pathway

Tumor Biology

Volumn 36, Issue 2, 2015, Pages 1279-1288

  Xie, Juan ^a   Xu, Yinyan ^a   Huang, Xinyan ^a   Chen, Yanni ^a   Fu, Jing ^a   Xi, Mingming ^a   Wang, Li ^a  

^a WOMEN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Berberine; Mitochondria; Reactive oxygen species

Indexed keywords

BERBERINE; CASPASE 3; CYTOCHROME C; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER CELL LINE; CANCER INHIBITION; CELL STRUCTURE; CELL VIABILITY; CHEMOSENSITIVITY; CONTROLLED STUDY; DEPOLARIZATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MTT ASSAY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; BIOSYNTHESIS; BREAST NEOPLASMS; CELL SURVIVAL; DRUG EFFECTS; FEMALE; GENETICS; MCF 7 CELL LINE; METABOLISM; PATHOLOGY;

APOPTOSIS; BERBERINE; BREAST NEOPLASMS; CASPASE 3; CELL SURVIVAL; FEMALE; HUMANS; MCF-7 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84923799798     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-2754-7     Document Type: Article

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