Nanoscopic Poly-DNA-cleaver for breast cancer regression with induced oxidative damage

Molecular Pharmaceutics

Volumn 11, Issue 11, 2014, Pages 4218-4227

  Misra, Santosh K ^a,b   Kus, Joseph ^a,b   Kim, Sumin ^a,b   Pan, Dipanjan ^a,b  

^a CARLE FOUNDATION HOSPITAL   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Blood contact properties; Breast cancer; Complement activation; DNA cleaving; DNA fragmentation; Nanometer sized agents; Polymer micelles

Indexed keywords

2 DEOXYRIBOSE; ANTINEOPLASTIC AGENT; ASCORBIC ACID; C POLY DNA CLEAVER; CETOMACROGOL; COPPER; E POLY DNA CLEAVER; PHENANTHROLINE; PLASMID DNA; POLYMER; UNCLASSIFIED DRUG; ANTIOXIDANT; DNA; ESTROGEN RECEPTOR; HYDROGEN PEROXIDE; MOLECULAR LIBRARY; NANOPARTICLE; OXIDIZING AGENT; PROGESTERONE RECEPTOR;

ARTICLE; BIOAVAILABILITY; CANCER CELL CULTURE; CANCER REGRESSION; CHEMICAL STRUCTURE; COMPLEMENT ACTIVATION; COMPLEX FORMATION; DNA CLEAVAGE; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC50; IN VITRO STUDY; MCF 7 CELL LINE; NANOENCAPSULATION; OXIDATIVE STRESS; PRIORITY JOURNAL; SYNTHESIS; ZETA POTENTIAL; BREAST NEOPLASMS; CHEMISTRY; FEMALE; GENETICS; METABOLISM; MOLECULAR LIBRARY; PATHOLOGY; PHARMACOLOGY; REGRESSION ANALYSIS;

ANTIOXIDANTS; ASCORBIC ACID; BREAST NEOPLASMS; DNA, NEOPLASM; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; HYDROGEN PEROXIDE; NANOPARTICLES; OXIDANTS; OXIDATIVE STRESS; POLYMERS; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; REGRESSION ANALYSIS; SMALL MOLECULE LIBRARIES;

EID: 84965185229     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500444c     Document Type: Article

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