Protective effect of curcumin in fructose-induced metabolic syndrome and in streptozotocin-induced diabetes in rats

Iranian Journal of Basic Medical Sciences

Volumn 19, Issue 6, 2016, Pages 585-593

  Bulboacă, Adriana ^a   Bolboacă, Sorana D ^a   Suciu, Habil Soimiţa ^a  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

Curcumin; Diabetes mellitus; Fructose; Metabolic syndrome Oxidative stress; Streptozotocin induced diabetes

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; CURCUMIN; FRUCTOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; STREPTOZOCIN; THIOL; TRIACYLGLYCEROL;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; INFLAMMATION; MALE; METABOLIC SYNDROME X; NONHUMAN; OXIDATIVE STRESS; PLETHYSMOGRAPHY; RAT; SPECTROPHOTOMETRY; SYSTOLIC BLOOD PRESSURE;

EID: 84978159440     PISSN: 20083866     EISSN: 20083874     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Tappy L, Lê KA, Tran C, Paquot N. Fructose and metabolic diseases: new findings, new questions. Nutrition 2010; 26:1044-1049.
2. Kawasaki T, Igarashi K, Koeda T, Sugimoto K, Nakagawa K, Hayashi S, et al. Rats fed fructose-enriched diets have characteristics of nonalcoholic hepatic steatosis. J Nutr 2009; 139:2067-2071.
3. Mamikutty N, Thent ZC, Sapri SR, Sahruddin NN, Mohd Yusof MR, Haji Suhaimi F. The establishment of metabolic syndrome model by induction of fructose drinking water in male Wistar rats. Biomed Res Int 2014; 2014:263897.
4. Spruss A, Kanuri G, Uebel K, Bischoff SC, Bergheim I. Role of the inducible nitric oxide synthase in the onset of fructose-induced steatosis in mice. Antioxid Redox Signal 2011; 14:2121-2135.
5. Cosenzi A, Bernobich E, Bonavita M, Gris F, Odoni G, Bellini G. Role of nitric oxide in the early renal changes induced by high fructose diet in rats. Kidney Blood Press Res 2002; 25:363-369.
6. Wu KL, Chao YM, Tsay SJ, Chen CH, Chan SH, Dovinova I, et al. Role of nitric oxide synthase uncoupling at rostral ventrolateral medulla in redox-sensitive hypertension associated with metabolic syndrome. Hypertension 2014; 64:815-824.
7. Mohamad Shahi M, Haidari F, Shiri MR. Com-parison of effect of resveratrol and vanadium on diabetes related dyslipidemia and hyperglycemia in streptozotocin induced diabetic rats. Adv Pharm Bull 2011; 1:81-86.
8. Musial DC, da Silva Júnior ED, da Silva RM, Miranda-Ferreira R, Lima-Landman MT, Jurkiewicz A, et al. Increase of angiotensin-converting enzyme activity and peripheral sympathetic dysfunction could contribute to hypertension development in streptozotocin-induced diabetic rats. Diab Vasc Dis Res 2013; 10:498-504.
9. Haluzík M, Nedvídková J, Skrha J. The influence of NO synthase inhibitor and free oxygen radicals scavenger-methylene blue-on streptozotocin-induced diabetes in rats. Physiol Res 1998; 47:337-341.
10. Negi PS, Jaypraskasha GK, Jagan Mohan Rao L, Sakariah KK. Antibacterial activity of turmeric oil: a by product from curcumin manufacture. J Agric Food Chem 1999; 47:4297-4300.
11. Nagajyothi F, Zhao D, Weiss LM, Tanowitz HB. Curcumin treatment provides protection against Trypanosoma cruzi infection. Parasitol Res 2012; 110:2491-2499.
12. Dias Ferreira F, Mossini SA, Dias Ferreira FM, Arrotéia CC, da Costa CL, Nakamura CV, et al. The inhibitory effects of Curcuma longa L. essential oil and curcumin on Aspergillus flavus link growth and morphology. Scientific World Journal 2013; 2013:343-804.
13. Jayaprakasha GK, Rao LJ, Sakarian KK. Antioxidant activities of curcumin, demethoxi curcumin and bisdemethoxy curcumin. Food Chem 2006; 98:720-724.
14. Minaiyan M, Zolfaghari B, Kamal A. Effect of hydroalcoholic and buthanolic extract of cucumis sativus seeds on blood glucose level of normal and streptozotocin-induced diabetic rats. Iran J Basic Med Sci 2011; 14:436-442.
15. Aggarwal BB, Kumar A, Bharti AC. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res 2003; 23:363-398.
16. Ashan H, Perveen N, Khan NU, Hadi SM. Pro-oxidant, anti-oxidant and cleavage activities on DNA of curcumin and its derivetes demethoxy curcumin and bisdemethoxi curcumin. Chem Biol Interact 1999; 121:161-175.
17. Chattopadhyay I, Biswas K, Bandyopadhyay U, Banerjee RK. Turmeric and curcumin: biological actions and medicinal applications. Curr Sci 2004; 87:44-53.
18. Bengmark SI, Mesa MD, Gil A. Plant-derived health: the effects of turmeric and curcuminoids. Nutr Hosp 2009; 24:273-281.
19. Rossini AA, Like AAA, Chick WL, Appel MC, Cahill GF Jr. Studies of streptozotocin-induced insulitis and diabetes. Proc Natl Acad Sci USA 1977; 74:2485-2489.
20. Amr AA, Elshazly SM. Ursodeoxycholic acid ameliorates fructose-induced metabolic syndrome in rats. PLoS One 2014; 9:e106993.
21. Alimohammadi S, Hobbenaghi R, Javanbakht J, Kheradmand D, Mortezaee R, Tavakoli M, et al. Protective and antidiabetic effects of extract from Nigella sativa on blood glucose concentrations against streptozotocin (STZ)-induced diabetic in rats: an experimental study with histopathological evaluation. Diagn Pathol 2013; 8:137.
22. Gupta SK, Kumar B, Nag TC, Agrawal SS, Agrawal R, Agrawal P, et al. Curcumin prevents experimental diabetic retinopathy in rats through its hypoglycemic, antioxidant, and anti-inflammatory mechanisms. J Ocul Pharmacol Ther 2011; 27:123-130.
23. Amani M, Noroozzadeh A, Badalzadeh R, Khosh-baten A. Effect of ascorbic acid supplementation on nitric oxide metabolites and systolic blood pressure in rats exposed to lead. Indian J Pharmacol 2010; 42:78-81.
24. Yagl K. Assay for blood plasma and serum peroxides. Methods Enzymol 1984; 105:28-31.
25. Hu ML. Measurement of protein thiol groups and glutathuine in plasma. Methods Enzymol 1994; 233:380-384.
26. Pârvu AE, Pârvu M, Vlase L, Miclea P, Mot AC, Silaghi-Dumitrescu R. Anti-inflammatory effects of Allium Schonoprasum L leaves. J Physiol Pharmacol 2014; 65:309-315.
27. Kawamura T, Yoshida K, Sugawara A, Nagasaka M, Mori N, Takeuchi K, et al. Regulation of skeletal muscle peroxisome proliferator-activated receptor gamma expression by exercise and angiotensin-converting enzyme inhibition in fructose-fed hypertensive rats. Hypertens Res 2004; 27:61-70.
28. Sherajee SJ, Rafiq K, Nakano D, Mori H, Kobara H, Hitomi H, et al. Aldosterone aggravates glucose intolerance induced by high fructose. Eur J Pharmacol 2013; 720:63-68.
29. Hwang IS, Ho H, Hoffman BB, Reaven GM. Fructose-induced insulin resistance and hypertension in rats. Hypertension 1987; 10:512-516.
30. Wu KL, Chan SH, Chan JY. Neuroinflammation and oxidative stress in rostral ventrolateral medulla contribute to neurogenic hypertension induced by systemic inflammation. J Neuroinflammation 2012; 9:212.
31. Soucek M, Kára T. [Stress-induced hypertension and diabetes mellitus]. Vnitr Lek 2001; 4:315-319.
32. Amin F, Mehmood MH, Siddiqui BS, Khatoon N, Gilani AH. Co-administration of Black seeds and Turmeric shows enhanced efficacy in preventing metabolic syndrome in fructose-fed rats. J Cardiovasc Pharmacol 2015; 65:176-183.
33. Suryanarayana P, Satyanarayana A, Balakrishna N, Kumar PU, Reddy GB. Effect of turmeric and curcumin on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rat. Med Sci Monit 2007; 13:BR286-292.
34. Hu GX, Lin H, Lian QQ, Zhou SH, Guo J, Zhou HY, et al. Curcumin as a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase 1: improving lipid profiles in high-fat-diet-treated rats. PLoS One 2013; 8:e49976.
35. Wickenberg J, Ingemansson SL, Hlebowicz J. Effects of Curcuma longa (turmeric) on postprandial plasma glucose and insulin in healthy subjects. Nutr J 2010; 9:43.
36. Srinivasan K. Dietary spices as beneficial modulators of lipid profile in conditions of metabolic disorders and diseases. Food Funct 2013;4:503-521.
37. Hassanin A, Malek HA, Saleh D. Heparin modulation on hepatic nitric oxide synthase in experimental steatohepatitis. Exp Ther Med 2014; 8:1551-1558.
38. Abolfathi AA, Mohajeri D, Rezaie A, Nazeri M. Protective effects of green tea extract against hepatic tissue injury in streptozotocin-induced diabetic rats. Evid Based Complement Alternat Med 2012; 2012:740671.
39. Al-Rubaei ZM, Mohammad TU, Ali LK. Effects of local curcumin on oxidative stress and total antioxidant capacity in vivo study. Pak J Biol Sci 2014; 17:1237-1241.
40. Janero DR. Malondialdehide and thiogbarbituric acid-reactivity as adiagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radic Biol Med 1990; 9:515-540.
41. Suganthi R, Rajamani S, Ravichandran MK, Anuradha CV. Effect of food seasoning spices mixture on biomarkers of oxidative stress in tissues of fructose-fed insulin-resistant rats. J Med Food 2007; 10:149-153.
42. Lung CC, Pinnas JL, Yahya MD, Meinke GC, Mooradian AD. Malondialdehyde modified proteins and their antibodies in the plasma of control and streptozotocin induced diabetic rats. Life Sci 1993; 52:329-337.
43. 2 and peroxynitrite in membranes: physiological implications. Free Radic Res 1999; 31:597-606.
44. Husain K, Hazelrigg SR. Oxidative in jury due to chronic nitric synthase inhibition in rat: effect of regular exercise on the heart. Biochim Biophys Acta 2002; 1587:75-82.
45. Volpe CM, Abreu LF, Gomes PS, Gonzaga RM, Veloso CA, Nogueira-Machado JA. The production of nitric oxide, IL-6, and TNF-alpha in palmitate-stimulated PBMNCs is enhanced through hyperglycemia in diabetes. Oxid Med Cell Longev 2014; 2014:479587.
46. Nathan C, Xie Q-W. Nitric oxide synthases: roles, tolls, and controls. Cell 1994; 78:915-918.
47. Aggarwal BB, Harikumar KB. Potential thera-peutic effects of curcumin, the antiinflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol 2009; 41:40-59.
48. Rokutan K, Thomas JA, Sies H. Specific S-thiolation of a 30-kDa cytosolic protein from rat liver under oxidative stress. Eur J Biochem 1989; 179:233-239.
49. Fisher-Wellman KH, Gilliam LA, Lin CT, Cathey BL, Lark DS, Neufer PD. Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload. Free Radic Biol Med 2013; 65:1201-1208.
50. Francik R, Krośniak M, Sanocka I, Bartoń H, Hebda T, Francik S. Aronia melanocarpa treatment and antioxidant status in selected tissues in wistar rats. Biomed Res Int 2014; 2014:457085.
51. Kishi T. Regulation of the sympathetic nervous system by nitric oxide and oxidative stress in the rostral ventrolateral medulla: 2012 Academic Conference Award from the Japanese Society of Hypertension. Hypertens Res 2013; 36:845-851.