A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion

Acta Diabetologica

Volumn 51, Issue 3, 2014, Pages 403-411

  Bonifacio, Ezio ^a,b   Krumsiek, Jan ^c   Winkler, Christiane ^d,e   Theis, Fabian J ^c,e   Ziegler, Anette Gabriele ^d,e  

^a CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^b GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d Forschergruppe Diabetes EV   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Islet autoimmunity; Progression; Type 1 diabetes; Type 1 diabetes susceptibility genes

Indexed keywords

AUTOANTIBODY; PANCREAS ISLET CELL ANTIBODY; DEAD BOX PROTEIN; HLA DQ ANTIGEN; IFIH1 PROTEIN, HUMAN; INSULIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA;

ALLELE; ARTICLE; AUTOIMMUNITY; CD25 GENE; CELL DESTRUCTION; CHILD; COHORT ANALYSIS; CTLA4 GENE; DISEASE COURSE; DISEASE PREDISPOSITION; ERBB3 GENE; FOLLOW UP; GENE; HIGH RISK PATIENT; HUMAN; IFIH1 GENE; IL10 GENE; IL18RAP GENE; IL2 GENE; INS GENE; INSULIN DEPENDENT DIABETES MELLITUS; KIAA0350 GENE; LONGITUDINAL STUDY; LOW RISK PATIENT; PANCREAS ISLET BETA CELL; PATIENT IDENTIFICATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PTPN2 GENE; PTPN22 GENE; RISK ASSESSMENT; SCHOOL CHILD; SEROCONVERSION; SH2B3 GENE; ADOLESCENT; FEMALE; GENETIC PREDISPOSITION; GENETICS; GERMANY; IMMUNOLOGY; INFANT; PANCREAS ISLET; PRESCHOOL CHILD; YOUNG ADULT;

ADOLESCENT; AUTOANTIBODIES; AUTOIMMUNITY; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DEAD-BOX RNA HELICASES; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; GERMANY; HLA-DQ ANTIGENS; HUMANS; INFANT; INSULIN; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; ISLETS OF LANGERHANS; YOUNG ADULT;

EID: 84905401240     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-013-0526-2     Document Type: Article

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