Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis

Respiratory Research

Volumn 12, Issue 1, 2011, Pages 1-16

  Londhe, Vedang A ^a   Maisonet, Tiffany M ^a   Lopez, Benjamin ^a   Jeng, Jade Ming ^a   Xiao, Jing ^c   Li, Changgong ^b   Minoo, Parviz ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Alveolar development; Alveolar maturation; Apoptosis; Inhibitor of kappa B kinase beta (IKK ); Nkx2.1; Nuclear factor B (NF B); Surfactant protein C (SP C); Thyroid transcription factor (TTF 1); Vascular endothelial growth factor (VEGF)

Indexed keywords

I KAPPA B KINASE BETA; MESSENGER RNA; VASCULOTROPIN; APOPTOSIS REGULATORY PROTEIN; I KAPPA B KINASE; IKBKB PROTEIN, MOUSE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

ANIMAL EXPERIMENT; ANIMAL HUSBANDRY; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRANCHING MORPHOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; FETUS LUNG MATURITY; GENETIC RECOMBINATION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS EPITHELIUM; LUNG DEVELOPMENT; MOUSE; NONHUMAN; PROGENY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; COMPARATIVE STUDY; DRUG ANTAGONISM; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; LUNG; LUNG ALVEOLUS; METABOLISM; MYOFIBROBLAST; PATHOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT; RESPIRATORY TRACT MUCOSA;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; I-KAPPA B KINASE; LUNG; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOFIBROBLASTS; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84977750711     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-12-134     Document Type: Article

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